Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
Subcategories of "Tyrosine Kinase/Adaptors"
- ALK(135 products)
- CSF-1R(42 products)
- EGFR(589 products)
- Ephrin Receptor(25 products)
- FLT(90 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- HER(3 products)
- Hck(3 products)
- IGF-1R(104 products)
- PDGFR(129 products)
- PYK2(7 products)
- Src(82 products)
- TAM Receptor(34 products)
- Tie-2(20 products)
- Trk receptor(56 products)
- Tyrosine Kinases(20 products)
- VEGFR(245 products)
- c-Fms(112 products)
- c-Kit(116 products)
- c-Met/HGFR(139 products)
- c-RET(61 products)
Show 13 more subcategories
Found 1106 products of "Tyrosine Kinase/Adaptors"
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NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Formula:C11H6N4O4SPurity:99.84%Color and Shape:SolidMolecular weight:290.25Ref: TM-T6908
2mg35.00€5mg50.00€10mg66.00€25mg124.00€50mg188.00€100mg354.00€200mg495.00€1mL*10mM (DMSO)52.00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purity:98.11% - 99.87%Color and Shape:SolidMolecular weight:718.08AZD3229
CAS:AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.Formula:C24H26FN7O3Purity:98.83%Color and Shape:SolidMolecular weight:479.51Ref: TM-T5409
1mg44.00€5mg87.00€10mg140.00€25mg248.00€50mg364.00€100mg509.00€200mg698.00€1mL*10mM (DMSO)99.00€Mubritinib
CAS:Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Formula:C25H23F3N4O2Purity:98.61% - 99.85%Color and Shape:SolidMolecular weight:468.471-Naphthyl PP1 hydrochloride
CAS:1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormula:C19H20ClN5Purity:98.63%Color and Shape:SolidMolecular weight:353.85c-Kit-IN-1
CAS:c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).Formula:C26H21F2N5O3Purity:98.72% - 98.73%Color and Shape:SolidMolecular weight:489.47Ref: TM-T4332
1mg39.00€5mg81.00€10mg120.00€25mg235.00€50mg373.00€100mg610.00€200mg840.00€1mL*10mM (DMSO)88.00€Alectinib hydrochloride
CAS:Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)Formula:C30H35ClN4O2Purity:99.74% - 99.96%Color and Shape:SolidMolecular weight:519.08ALW-II-41-27
CAS:ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor), an Eph receptor tyrosine kinase inhibitor, is used for cancer therapy.Formula:C32H32F3N5O2SPurity:97.01% - 99.52%Color and Shape:SolidMolecular weight:607.69Ref: TM-T4344
1mg63.00€5mg159.00€10mg236.00€25mg371.00€50mg522.00€100mg713.00€200mg982.00€1mL*10mM (DMSO)216.00€Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Formula:C24H25ClFN5O2Purity:99.4% - 99.72%Color and Shape:SolidMolecular weight:469.94Ref: TM-T2483
1mg38.00€2mg49.00€5mg79.00€10mg127.00€25mg173.00€50mg227.00€100mg354.00€200mg444.00€500mg730.00€1mL*10mM (DMSO)79.00€LDC1267
CAS:LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).Formula:C30H26F2N4O5Purity:99.38% - 99.88%Color and Shape:SolidMolecular weight:560.55Ref: TM-T2311
1mg34.00€2mg49.00€5mg73.00€10mg100.00€25mg165.00€50mg235.00€100mg396.00€1mL*10mM (DMSO)88.00€Ruxolitinib (S enantiomer)
CAS:Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.Formula:C17H18N6Purity:99.37% - 99.79%Color and Shape:SolidMolecular weight:306.36Tyrphostin AG 528
CAS:Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).Formula:C18H14N2O3Purity:99.64%Color and Shape:SolidMolecular weight:306.32Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormula:C18H22N2OPurity:98.21% - 99.87%Color and Shape:Yellow SolidMolecular weight:282.38Glumetinib
CAS:Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).
Formula:C21H17N9O2SPurity:99.79%Color and Shape:SolidMolecular weight:459.48PP 3
CAS:PP 3 is a Negative control for the Src kinase inhibitor PP 2Formula:C11H9N5Purity:98.61%Color and Shape:Whit To Off-White SolidMolecular weight:211.22Ensartinib hydrochloride
CAS:Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of knownFormula:C26H29Cl4FN6O3Purity:98.73%Color and Shape:SolidMolecular weight:634.36Ref: TM-T22324
1mg59.00€5mg127.00€10mg188.00€25mg404.00€50mg645.00€100mg938.00€200mg1,264.00€1mL*10mM (DMSO)170.00€MID-1
CAS:MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.Formula:C12H11N3O4SPurity:99.39%Color and Shape:SolidMolecular weight:293.3Ref: TM-T8773
1mg50.00€5mg97.00€10mg145.00€25mg259.00€50mg383.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)109.00€Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formula:C36H56O13Purity:99.66% - 99.74%Color and Shape:SolidMolecular weight:696.82Ref: TM-T5S1982
1mg35.00€5mg77.00€10mg106.00€25mg170.00€50mg253.00€100mg375.00€500mg892.00€1mL*10mM (DMSO)107.00€UNC569
CAS:UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.Formula:C22H29FN6Purity:98.91% - 99.67%Color and Shape:SolidMolecular weight:396.5Ehp-inhibitor-2
CAS:Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.Formula:C17H13N5OPurity:97.88%Color and Shape:SolidMolecular weight:303.32Ref: TM-T5452
2mg35.00€5mg55.00€10mg96.00€25mg146.00€50mg210.00€100mg309.00€200mg444.00€1mL*10mM (DMSO)62.00€GIP (1-30) amide, porcine acetate
GIP (1-30) amide, porcine is a GIP receptor agonist that stimulates insulin and mildly inhibits gastric acid.Formula:C164H249N41O49SPurity:98.50%Color and Shape:SolidMolecular weight:3611.04Osimertinib
CAS:Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.Formula:C28H33N7O2Purity:99.32% - >99.99%Color and Shape:SolidMolecular weight:499.61Ref: TM-T2490
1g138.00€2g197.00€5g329.00€2mg34.00€5mg52.00€10mg55.00€25mg67.00€50mg80.00€100mg94.00€500mg114.00€1mL*10mM (DMSO)52.00€EGFR/ErbB-2/ErbB-4 inhibitor-2
CAS:EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)Formula:C23H21N3O3Purity:99.55%Color and Shape:SolidMolecular weight:387.43Ref: TM-T21954
1mg50.00€5mg94.00€10mg140.00€25mg245.00€50mg369.00€100mg537.00€200mg712.00€1mL*10mM (DMSO)103.00€CHIR-98014
CAS:CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.
Formula:C20H17Cl2N9O2Purity:97.25% - 99.59%Color and Shape:SolidMolecular weight:486.31CREBtide acetate(149155-45-3 free base)
CREBtide acetate is a synthetic substrate for PKA (Km=3.9 μM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).Formula:C75H133N29O21Purity:96.13%Color and Shape:SolidMolecular weight:1777.07Taletrectinib
CAS:Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3.
Formula:C29H34FN5O5Purity:99.87% - 99.96%Color and Shape:SolidMolecular weight:551.61WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formula:C16H15N3O3Purity:99.21%Color and Shape:SolidMolecular weight:297.31BMS 777607
CAS:BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3. BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.Formula:C25H19ClF2N4O4Purity:98.89% - >99.99%Color and Shape:SolidMolecular weight:512.89Ref: TM-T2699
1mg35.00€5mg79.00€10mg124.00€25mg217.00€50mg359.00€100mg533.00€500mg1,169.00€1mL*10mM (DMSO)92.00€Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:272.25Ref: TM-T6427
1mg40.00€2mg52.00€5mg84.00€10mg101.00€25mg202.00€50mg326.00€100mg520.00€1mL*10mM (DMSO)82.00€SKLB 610
CAS:SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively,
Formula:C21H16F3N3O3Purity:99.33% - 99.83%Color and Shape:SolidMolecular weight:415.37MK-8033
CAS:MK-8033 is a new and selective dual ATP competitive c-Met/Ron inhibitor (IC50: 1 nM Wt c-Met).Formula:C25H21N5O3SPurity:97.16%Color and Shape:SolidMolecular weight:471.53GLPG0634 analog
CAS:GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formula:C23H18N6O2Purity:99.52% - >99.99%Color and Shape:SolidMolecular weight:410.43Ref: TM-T3076
1mg40.00€2mg52.00€5mg88.00€10mg144.00€25mg264.00€50mg465.00€100mg658.00€500mg1,378.00€1mL*10mM (DMSO)87.00€PD158780
CAS:PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.Formula:C14H12BrN5Purity:98.81%Color and Shape:SolidMolecular weight:330.18Ref: TM-T5410
1mg38.00€5mg80.00€10mg113.00€25mg205.00€50mg358.00€100mg523.00€200mg750.00€1mL*10mM (DMSO)93.00€Eph inhibitor 2
CAS:Eph inhibitor 2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.Formula:C18H15N5OPurity:99.01%Color and Shape:SolidMolecular weight:317.34Ref: TM-T5451
1mg95.00€2mg125.00€5mg188.00€10mg284.00€25mg515.00€50mg742.00€100mg1,035.00€500mg2,080.00€1mL*10mM (DMSO)187.00€FGFR4-IN-1
CAS:FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
Formula:C24H27N7O5Purity:98.96%Color and Shape:SolidMolecular weight:493.52SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purity:99.46%Color and Shape:SolidMolecular weight:265.31PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formula:C15H16ClN5Purity:98% - 98.21%Color and Shape:White SolidMolecular weight:301.77Ref: TM-T6266
2mg44.00€5mg65.00€10mg110.00€25mg178.00€50mg304.00€100mg482.00€200mg687.00€1mL*10mM (DMSO)71.00€Tyrphostin AG30
CAS:Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.Formula:C10H7NO4Purity:99.02%Color and Shape:SolidMolecular weight:205.17PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurity:99.92%Color and Shape:SolidMolecular weight:532.51Ref: TM-T23127
1mg34.00€5mg96.00€10mg141.00€25mg289.00€50mg465.00€100mg662.00€200mg888.00€1mL*10mM (DMSO)118.00€Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formula:C30H34N8O3Purity:98.7% - 99.90%Color and Shape:SolidMolecular weight:554.64Ref: TM-T4485
1mg48.00€2mg63.00€5mg92.00€10mg137.00€25mg226.00€50mg325.00€100mg469.00€200mg692.00€1mL*10mM (DMSO)110.00€β-Hydroxyisovalerylshikonin
CAS:Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFormula:C21H24O7Purity:98.16%Color and Shape:SolidMolecular weight:388.41PKG drug G1
CAS:PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.Formula:C13H11N3OSPurity:97.57% - 97.67%Color and Shape:SolidMolecular weight:257.31MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.382-D08
CAS:2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.Formula:C15H10O5Purity:98.58% - 98.95%Color and Shape:SolidMolecular weight:270.24Ref: TM-T7379
2mg39.00€5mg54.00€10mg93.00€25mg170.00€50mg268.00€100mg447.00€200mg650.00€1mL*10mM (DMSO)59.00€Dacomitinib hydrate
CAS:Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family ofFormula:C24H27ClFN5O3Purity:99.52%Color and Shape:SolidMolecular weight:487.96Ref: TM-T19965
5mg50.00€10mg80.00€25mg105.00€50mg140.00€100mg212.00€200mg311.00€1mL*10mM (DMSO)60.00€CH7057288
CAS:CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.Formula:C32H31N3O5SPurity:99.92%Color and Shape:SolidMolecular weight:569.67TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C23H20N6OPurity:99.71%Color and Shape:SolidMolecular weight:396.44Ref: TM-T16996
1mg87.00€2mg124.00€5mg188.00€10mg311.00€25mg628.00€50mg838.00€100mg1,130.00€200mg1,549.00€1mL*10mM (DMSO)215.00€Olmutinib hydrochloride
CAS:Olmutinib is a third-gen EGFR inhibitor for T790M-positive lung cancer, blocking phosphorylation and tumor pathways. Approved in Korea (2016).Formula:C26H28Cl2N6O2SColor and Shape:SolidMolecular weight:559.51Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:SolidMolecular weight:938.71Pralsetinib
CAS:Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918TFormula:C27H32FN9O2Purity:97.88% - 99.8%Color and Shape:SolidMolecular weight:533.6Ref: TM-TQ0277
1mg43.00€5mg103.00€10mg145.00€25mg283.00€50mg439.00€100mg660.00€1mL*10mM (DMSO)120.00€LDN-214117
CAS:LDN-214117 is a potent and selective ALK2 inhibitor.
Formula:C25H29N3O3Purity:98% - 99.82%Color and Shape:SolidMolecular weight:419.52RG14620
CAS:RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.Formula:C14H8Cl2N2Purity:99.82% - 99.87%Color and Shape:SolidMolecular weight:275.13squarunkinA
CAS:squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-Formula:C25H32F3N5O4Purity:99.29%Color and Shape:SolidMolecular weight:523.55Malantide acetate(86555-35-3 free base)
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptideFormula:C74H128N22O23Purity:>99.99%Color and Shape:SolidMolecular weight:1693.97PKI 14-22 amide, myristoylated Acetate
PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP.Formula:C55H104N20O14Purity:96.34%Color and Shape:SolidMolecular weight:1269.54Ref: TM-T21983L
1mg269.00€5mg603.00€10mg898.00€25mg1,333.00€50mg1,791.00€100mg2,422.00€1mL*10mM (DMSO)1,161.00€SU5205
CAS:SU5205 is a VEGFR2 inhibitor.
Formula:C15H10FNOPurity:99.62% - 99.67%Color and Shape:SolidMolecular weight:239.24Allitinib tosylate
CAS:Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.Formula:C31H26ClFN4O5SPurity:98.46% - 98.68%Color and Shape:SolidMolecular weight:621.08PKG inhibitor peptide TFA (82801-73-8 free base)
PKG inhibitor peptide TFA (82801-73-8 free base) is an inhibitor of ATP-competitive cGMP-dependent protein kinase (PKG).Formula:C40H75F3N18O12Purity:98%Color and Shape:SolidMolecular weight:1057.13Bemcentinib
CAS:Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.Formula:C30H34N8Purity:97% - 99.8%Color and Shape:SolidMolecular weight:506.64Ref: TM-T6269
1mg40.00€2mg52.00€5mg87.00€10mg144.00€25mg212.00€50mg274.00€100mg465.00€200mg622.00€500mg948.00€1mL*10mM (DMSO)92.00€BIBF0775
CAS:BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).
Formula:C31H34N4O2Purity:99.45% - 99.79%Color and Shape:SolidMolecular weight:494.63Epidermal Growth Factor
CAS:EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.Formula:C270H401N73O83S7Purity:97.17%Color and Shape:SolidMolecular weight:6222CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formula:C14H18N2O5Purity:99.68%Color and Shape:White To Off-White SolidMolecular weight:294.3RU-301
CAS:RU-301 is a novel pan-tam inhibitorFormula:C21H19F3N4O4SPurity:98.87%Color and Shape:SolidMolecular weight:480.46Ref: TM-T7425
1mg98.00€5mg222.00€10mg344.00€25mg587.00€50mg803.00€100mg1,063.00€1mL*10mM (DMSO)241.00€AZ-5104
CAS:AZ5104 is a potent EGFR inhibitor.Formula:C27H31N7O2Purity:98.40% - 99.59%Color and Shape:Solid PowderMolecular weight:485.58eCF506
CAS:eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)Formula:C26H38N8O3Purity:97.85% - 98.16%Color and Shape:SolidMolecular weight:510.63EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formula:C21H18F3N5OPurity:98.3% - 99.76%Color and Shape:SolidMolecular weight:413.4Ref: TM-T5168
1mg82.00€5mg159.00€10mg259.00€25mg520.00€50mg740.00€100mg1,008.00€500mg2,015.00€1mL*10mM (DMSO)168.00€Poziotinib hydrochloride
CAS:Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.Formula:C23H22Cl3FN4O3Purity:99.69% - 99.81%Color and Shape:SolidMolecular weight:527.8SAR-20347
CAS:SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).Formula:C21H18ClFN4O4Purity:98.99% - 99.77%Color and Shape:SolidMolecular weight:444.84Ref: TM-T4210
1mg35.00€5mg80.00€10mg116.00€25mg227.00€50mg354.00€100mg588.00€200mg818.00€1mL*10mM (DMSO)88.00€cFMS Receptor Inhibitor II
CAS:cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFormula:C23H20N4OPurity:99.8%Color and Shape:SolidMolecular weight:368.43Ref: TM-T5586
1mg49.00€2mg65.00€5mg97.00€10mg154.00€25mg255.00€50mg376.00€100mg547.00€1mL*10mM (DMSO)106.00€BLU9931
CAS:BLU9931 is the first selective small molecule inhibitor of FGFR4.
Formula:C26H22Cl2N4O3Purity:96.958% - 99.85%Color and Shape:SolidMolecular weight:509.38Rebastinib
CAS:DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,
Formula:C30H28FN7O3Purity:99.53% - 99.79%Color and Shape:SolidMolecular weight:553.59Methyl 2,5-dihydroxycinnamate
CAS:Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.Formula:C10H10O4Purity:99.60%Color and Shape:CrystallineMolecular weight:194.18HG-14-10-04
CAS:HG-14-10-04 is a potent and specific ALK inhibitor.Formula:C29H34ClN7OPurity:99.75% - >99.99%Color and Shape:SolidMolecular weight:532.08Ref: TM-T4015
1mg49.00€5mg92.00€10mg152.00€25mg222.00€50mg289.00€100mg409.00€200mg590.00€1mL*10mM (DMSO)111.00€PKG Substrate acetate(81187-14-6 free base)
PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG).PKG Substrate is a selective substrate for protein kinase G (PKG) with aFormula:C37H71N17O13Purity:99.30%Color and Shape:SolidMolecular weight:962.08UM-164
CAS:UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.
Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68KYL acetate(676657-00-4 free base)
EphA4 inhibitor, Kd: 0.8 μM, IC50: 6.34 μM. Protects synapses and spines, maintains LTP. Long half-life: 8-12h. Neuroprotective.Formula:C76H112N14O19Purity:99.75%Color and Shape:SolidMolecular weight:1525.78Saracatinib
CAS:Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formula:C27H32ClN5O5Purity:98% - 99.63%Color and Shape:SolidMolecular weight:542.03Tuxobertinib
CAS:Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.Formula:C29H29ClN6O4Purity:99.22%Color and Shape:SolidMolecular weight:561.03Ref: TM-T9072
2mg40.00€5mg60.00€10mg96.00€25mg188.00€50mg354.00€100mg525.00€200mg752.00€1mL*10mM (DMSO)74.00€LOXO-195
CAS:(6RS)-LOXO-195 (BAY 2731954) is a potent and selective Trk tyrosine kinase inhibitor.Formula:C20H21FN6OPurity:99.54%Color and Shape:SolidMolecular weight:380.42Olafertinib
CAS:Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.Formula:C29H28F2N6O2Purity:98.62% - 99.706%Color and Shape:SolidMolecular weight:530.57Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formula:C22H23ClFN5O3Purity:98.20% - 99.36%Color and Shape:White To Off-White SolidMolecular weight:459.9ML167
CAS:ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.
Formula:C19H17N3O3Purity:99.82% - >99.99%Color and Shape:SolidMolecular weight:335.36MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formula:C20H14Cl2FN5O2SPurity:97.6% - >99.99%Color and Shape:SolidMolecular weight:478.33Ref: TM-T4296
1mg64.00€2mg95.00€5mg170.00€10mg274.00€25mg464.00€50mg640.00€100mg847.00€200mg1,159.00€1mL*10mM (DMSO)180.00€Bafetinib
CAS:Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.Formula:C30H31F3N8OPurity:94.16% - 99.68%Color and Shape:SolidMolecular weight:576.62Ref: TM-T6311
1mg34.00€2mg49.00€5mg74.00€10mg98.00€25mg150.00€50mg178.00€100mg333.00€200mg432.00€1mL*10mM (DMSO)95.00€WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2Repotrectinib
CAS:Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01/5.3/1.08/1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.
Formula:C18H18FN5O2Purity:99.92% - >99.99%Color and Shape:SolidMolecular weight:355.37XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ref: TM-T17267
1mg52.00€2mg73.00€5mg94.00€10mg141.00€25mg244.00€50mg371.00€100mg552.00€1mL*10mM (DMSO)104.00€Tetramethylcurcumin
CAS:Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it alsoFormula:C25H28O6Purity:97.69% - 99.94%Color and Shape:SolidMolecular weight:424.49AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Formula:C19H18N2O3Purity:98.02% - 99.94%Color and Shape:SolidMolecular weight:322.36PKA inhibitor fragment (6-22) amide Acetate
PKA inhibitor fragment (6-22) amide Acetate is a synthetic peptide which selectively inhibits PKA activity by binding to its substrate site (IC50 < 2 nM).Formula:C82H134N28O26Purity:99.30%Color and Shape:SolidMolecular weight:1928.11Ref: TM-T21674L
1mg95.00€2mg123.00€5mg170.00€10mg279.00€25mg467.00€50mg680.00€100mg938.00€1mL*10mM (DMSO)457.00€123C4
CAS:123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase EPHA4 (Ki=0.65 μM)[1].Formula:C43H47ClN8O6Purity:98.94%Color and Shape:SolidMolecular weight:807.34Ref: TM-TP1561
1mg137.00€5mg295.00€10mg485.00€25mg772.00€50mg1,035.00€100mg1,395.00€1mL*10mM (DMSO)480.00€AG-1478
CAS:AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
Formula:C16H14ClN3O2Purity:99.03% - 99.71%Color and Shape:SolidMolecular weight:315.75AG 1406
CAS:AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.Formula:C16H18N2OPurity:98.12%Color and Shape:SolidMolecular weight:254.33ZAP-180013
CAS:ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).
Formula:C19H17Cl2N3O4SPurity:98.89%Color and Shape:SolidMolecular weight:454.33Su1498
CAS:Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.
Formula:C25H30N2O2Purity:99.54%Color and Shape:SolidMolecular weight:390.527-Hydroxy-4H-chromen-4-one
CAS:7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).Formula:C9H6O3Purity:97.65%Color and Shape:SolidMolecular weight:162.14WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Formula:C16H15N3O2Purity:99.66% - 99.92%Color and Shape:SolidMolecular weight:281.31UNC2250
CAS:UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM).Formula:C24H36N6O2Purity:98.57% - 99.87%Color and Shape:SolidMolecular weight:440.58BTK IN-1
CAS:BTK IN-1 (SNS062 analog) (SNS062 analog) is an effective BTK inhibitor (IC50: <100 nM).
Formula:C19H21ClN6OPurity:97.38%Color and Shape:SolidMolecular weight:384.86Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purity:97.89% - 98.66%Color and Shape:SolidMolecular weight:491.39Ref: TM-TQ0166
1mg107.00€2mg156.00€5mg236.00€10mg457.00€25mg750.00€50mg1,026.00€1mL*10mM (DMSO)255.00€
