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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • Cyclovirobuxine D

    CAS:
    <p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>
    Formula:C26H46N2O
    Purity:97.78% - 98%
    Color and Shape:Solid
    Molecular weight:402.66
  • Berberine hydrogen sulphate

    CAS:
    <p>Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.</p>
    Formula:C20H19NO8S
    Purity:99% - 99.79%
    Color and Shape:Yellow Crystals Off-White To Yellow Powder
    Molecular weight:433.43
  • Tenovin-1

    CAS:
    <p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>
    Formula:C20H23N3O2S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:369.48
  • Reversine

    CAS:
    <p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>
    Formula:C21H27N7O
    Purity:98% - 98.42%
    Color and Shape:Solid
    Molecular weight:393.49
  • Galangin

    CAS:
    <p>Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.</p>
    Formula:C15H10O5
    Purity:98.24% - 99.93%
    Color and Shape:Yellowish Needle-Like Crystal
    Molecular weight:270.24
  • Gemcitabine hydrochloride

    CAS:
    <p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>
    Formula:C9H11F2N3O4·HCl
    Purity:99.28% - 99.98%
    Color and Shape:White Crystalline Granular Odorless
    Molecular weight:299.66
  • JNJ-42165279

    CAS:
    <p>JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.</p>
    Formula:C18H17ClF2N4O3
    Purity:99.67% - 99.88%
    Color and Shape:Solid
    Molecular weight:410.8
  • Ponatinib

    CAS:
    <p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>
    Formula:C29H27F3N6O
    Purity:98% - 99.60%
    Color and Shape:Solid
    Molecular weight:532.56
  • Purmorphamine

    CAS:
    <p>Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.</p>
    Formula:C31H32N6O2
    Purity:97.19% - 99.48%
    Color and Shape:Light Tan Solid
    Molecular weight:520.62
  • LC3-mHTT-IN-AN2

    CAS:
    <p>LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.</p>
    Formula:C15H10O4
    Purity:98.82% - ≥98%
    Color and Shape:Solid
    Molecular weight:254.24
  • SAR405

    CAS:
    <p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>
    Formula:C19H21ClF3N5O2
    Purity:99.42% - 99.79%
    Color and Shape:Solid
    Molecular weight:443.85
  • Ethyl 3,4-dihydroxybenzoate

    CAS:
    <p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>
    Formula:C9H10O4
    Purity:99.88%
    Color and Shape:White Crystal Or Powder
    Molecular weight:182.17
  • GSK621

    CAS:
    <p>GSK621 is a specific and potent AMPK activator.</p>
    Formula:C26H20ClN3O5
    Purity:97.02% - 97.05%
    Color and Shape:Solid
    Molecular weight:489.91
  • Regorafenib

    CAS:
    <p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>
    Formula:C21H15ClF4N4O3
    Purity:98% - 99.95%
    Color and Shape:Solid
    Molecular weight:482.82
  • Neflamapimod

    CAS:
    <p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>
    Formula:C19H9Cl2F2N3OS
    Purity:97.88% - 99.75%
    Color and Shape:Solid
    Molecular weight:436.26
  • Enalaprilat Dihydrate

    CAS:
    <p>Enalaprilat Dihydrate (MK-422 Dihydrate) (IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor.</p>
    Formula:C18H24N2O5·2H2O
    Purity:99.46% - 99.78%
    Color and Shape:Solid
    Molecular weight:348.4
  • 3BDO

    CAS:
    <p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>
    Formula:C18H17NO5
    Purity:97.76%
    Color and Shape:Solid
    Molecular weight:327.33
  • Mavorixafor trihydrochloride

    CAS:
    <p>Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.</p>
    Formula:C21H30Cl3N5
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:458.86
  • Mirdametinib

    CAS:
    <p>Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.</p>
    Formula:C16H14F3IN2O4
    Purity:99.11% - 99.63%
    Color and Shape:White Powder
    Molecular weight:482.19
  • KN-92 phosphate

    CAS:
    <p>KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.</p>
    Formula:C24H28ClN2O7PS
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:554.98
  • WYC-209

    CAS:
    <p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>
    Formula:C20H20N2O3S
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:368.45
  • Afatinib Dimaleate

    CAS:
    <p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>
    Formula:C32H33ClFN5O11
    Purity:98.11% - 99.87%
    Color and Shape:Solid
    Molecular weight:718.08
  • DBEQ

    CAS:
    <p>DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.</p>
    Formula:C22H20N4
    Purity:98.93% - ≥95%
    Color and Shape:Solid
    Molecular weight:340.42
  • Pseudolaric Acid B

    CAS:
    <p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>
    Formula:C23H28O8
    Purity:98.91% - 99.84%
    Color and Shape:Solid
    Molecular weight:432.46
  • Regorafenib monohydrate

    CAS:
    <p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>
    Formula:C21H17ClF4N4O4
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:500.83
  • Oleanolic Acid

    CAS:
    <p>Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.</p>
    Formula:C30H48O3
    Purity:97.04% - 98.51%
    Color and Shape:Solid
    Molecular weight:456.7
  • GW 4064

    CAS:
    <p>GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).</p>
    Formula:C28H22Cl3NO4
    Purity:98% - 99.94%
    Color and Shape:Solid
    Molecular weight:542.84
  • Fangchinoline

    CAS:
    <p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>
    Formula:C37H40N2O6
    Purity:99.86% - >99.99%
    Color and Shape:Solid
    Molecular weight:608.72
  • AZD 6482

    CAS:
    <p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values ​​of 0.69nM and 10nM.Cost-effective and quality-assured.</p>
    Formula:C22H24N4O4
    Purity:99.79% - 99.95%
    Color and Shape:Solid
    Molecular weight:408.45
  • JZL195

    CAS:
    <p>JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.</p>
    Formula:C24H23N3O5
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:433.46
  • ZSTK474

    CAS:
    <p>PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential</p>
    Formula:C19H21F2N7O2
    Purity:98.29% - 99.95%
    Color and Shape:White Powder
    Molecular weight:417.41
  • Obeticholic Acid

    CAS:
    <p>Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.</p>
    Formula:C26H44O4
    Purity:99.88% - 99.97%
    Color and Shape:Solid
    Molecular weight:420.63
  • Torin 2

    CAS:
    <p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>
    Formula:C24H15F3N4O
    Purity:98.31% - 99.32%
    Color and Shape:Solid
    Molecular weight:432.4
  • BC1618

    CAS:
    <p>BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.</p>
    Formula:C24H24F3NO2
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:415.45
  • Genipin

    CAS:
    <p>Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.</p>
    Formula:C11H14O5
    Purity:99.09% - 99.21%
    Color and Shape:Solid
    Molecular weight:226.23
  • 4,4'-Dimethoxychalcone

    CAS:
    <p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>
    Formula:C17H16O3
    Purity:99.57%
    Color and Shape:Solid
    Molecular weight:268.31
  • Typhaneoside

    CAS:
    <p>Typhaneoside (Aervitrin) is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.</p>
    Formula:C34H42O20
    Purity:98.92% - 99.95%
    Color and Shape:Solid
    Molecular weight:770.69
  • sbp-7455

    CAS:
    <p>SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.</p>
    Formula:C16H17F3N4O2
    Purity:97.90% - 99.842%
    Color and Shape:Solid
    Molecular weight:354.33
  • SNX2112

    CAS:
    <p>SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.</p>
    Formula:C23H27F3N4O3
    Purity:98.75% - 99.46%
    Color and Shape:Solid
    Molecular weight:464.48
  • BX795

    CAS:
    <p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>
    Formula:C23H26IN7O2S
    Purity:98% - 99.57%
    Color and Shape:Solid
    Molecular weight:591.47
  • Hoechst 33342 trihydrochloride

    CAS:
    <p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>
    Formula:C27H31Cl3N6O
    Purity:98.73% - ≥98%
    Color and Shape:Solid
    Molecular weight:561.93
  • PI-103

    CAS:
    <p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>
    Formula:C19H16N4O3
    Purity:97.79% - 99.3%
    Color and Shape:Solid
    Molecular weight:348.36
  • Rasagiline Mesylate

    CAS:
    <p>Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.</p>
    Formula:C13H17NO3S
    Purity:99.33%
    Color and Shape:White Powder
    Molecular weight:267.34
  • Nordihydroguaiaretic acid

    CAS:
    <p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>
    Formula:C18H22O4
    Purity:97.82% - 99.91%
    Color and Shape:Solid
    Molecular weight:302.36
  • Dioscin

    CAS:
    <p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>
    Formula:C45H72O16
    Purity:99.85% - 99.87%
    Color and Shape:Solid
    Molecular weight:869.04
  • Elubrixin HCl

    CAS:
    <p>Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist.</p>
    Formula:C17H18Cl3FN4O4S
    Color and Shape:Solid
    Molecular weight:499.77
  • Piperlongumine

    CAS:
    <p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>
    Formula:C17H19NO5
    Purity:97.03% - 99.90%
    Color and Shape:Solid
    Molecular weight:317.34
  • Oxyresveratrol

    CAS:
    <p>1.</p>
    Formula:C14H12O4
    Purity:98.09% - 99.69%
    Color and Shape:Yellow Solid
    Molecular weight:244.24
  • LC3-mHTT-IN-AN1

    CAS:
    <p>LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B.</p>
    Formula:C15H9Br2NO3
    Purity:97.26%
    Color and Shape:Solid
    Molecular weight:411.04
  • Tezacaftor

    CAS:
    <p>Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.</p>
    Formula:C26H27F3N2O6
    Purity:98.84% - >99.99%
    Color and Shape:Solid
    Molecular weight:520.5
  • AS-605240

    CAS:
    <p>AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).</p>
    Formula:C12H7N3O2S
    Purity:97% - 99.91%
    Color and Shape:Solid
    Molecular weight:257.27
  • 3-Bromopyruvic acid

    CAS:
    <p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>
    Formula:C3H3BrO3
    Purity:95% - 99.644%
    Color and Shape:White To Pale Yellow Crystalline Powder
    Molecular weight:166.96
  • ML327

    CAS:
    <p>ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).</p>
    Formula:C19H18N4O4
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:366.37
  • Dorsomorphin

    CAS:
    <p>Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.</p>
    Formula:C24H25N5O
    Purity:98% - 99.06%
    Color and Shape:Solid
    Molecular weight:399.49
  • Rac-Belinostat

    CAS:
    <p>Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.</p>
    Formula:C15H14N2O4S
    Purity:99.67% - 99.96%
    Color and Shape:Solid
    Molecular weight:318.35
  • PHA-665752

    CAS:
    <p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), &gt;50-fold selectivity for c-Met than STKs or RTKs.</p>
    Formula:C32H34Cl2N4O4S
    Purity:97.05% - 98.82%
    Color and Shape:Solid
    Molecular weight:641.61
  • Alisertib

    CAS:
    <p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is &gt;200-fold higher for Aurora A than Aurora B.</p>
    Formula:C27H20ClFN4O4
    Purity:98.31% - >99.99%
    Color and Shape:Solid
    Molecular weight:518.92
  • LYS01

    CAS:
    <p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>
    Formula:C23H23Cl2N5
    Purity:98.28%
    Color and Shape:Solid
    Molecular weight:440.37
  • Polydatin

    CAS:
    <p>Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.</p>
    Formula:C20H22O8
    Purity:97.2% - 98.94%
    Color and Shape:White Fine Powder
    Molecular weight:390.38
  • Juglanin

    CAS:
    <p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>
    Formula:C20H18O10
    Purity:98.8% - 99.33%
    Color and Shape:Solid
    Molecular weight:418.35
  • Tubastatin A

    CAS:
    <p>Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.</p>
    Formula:C20H21N3O2
    Purity:97.22% - 99.51%
    Color and Shape:Solid
    Molecular weight:335.4
  • Meglutol

    CAS:
    <p>Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.</p>
    Formula:C6H10O5
    Purity:99.73% - 99.94%
    Color and Shape:Solid
    Molecular weight:162.14
  • Retro-2

    CAS:
    <p>Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.</p>
    Formula:C19H16N2OS
    Purity:98.15%
    Color and Shape:Solid
    Molecular weight:320.41
  • NVP-AEW541

    CAS:
    <p>NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based</p>
    Formula:C27H29N5O
    Purity:98.7% - 99.86%
    Color and Shape:Solid
    Molecular weight:439.55
  • Lys05

    CAS:
    <p>Lys05, a potent autophagy inhibitor, outperforms HCQ in cancer treatment, showing promise for drug development.</p>
    Formula:C23H26Cl5N5
    Purity:99.13% - 99.55%
    Color and Shape:Solid
    Molecular weight:549.75
  • MK-2206 dihydrochloride

    CAS:
    <p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>
    Formula:C25H23Cl2N5O
    Purity:99.228% - 99.94%
    Color and Shape:Solid
    Molecular weight:480.39
  • Bicyclol

    CAS:
    <p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>
    Formula:C19H18O9
    Purity:99.64% - 99.85%
    Color and Shape:Solid
    Molecular weight:390.34
  • Fasudil dihydrochloride

    CAS:
    <p>Fasudil dihydrochloride (HA-1077/AT877) is a RhoA/ROCK inhibitor with kinase-blocking properties and acts as a vasodilator.</p>
    Formula:C14H19Cl2N3O2S
    Color and Shape:Solid
    Molecular weight:364.29
  • Diosgenin glucoside

    CAS:
    <p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>
    Formula:C33H52O8
    Purity:97.17% - 99.44%
    Color and Shape:Solid
    Molecular weight:576.76
  • PD146176

    CAS:
    <p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>
    Formula:C15H11NS
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:237.32
  • Quisinostat dihydrochloride

    CAS:
    <p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性,高效的 pan-HDAC 抑制剂,具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>
    Formula:C21H28Cl2N6O2
    Purity:97.13%
    Color and Shape:Solid
    Molecular weight:467.39
  • MRT68921 dihydrochloride

    CAS:
    <p>MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).</p>
    Formula:C25H36Cl2N6O
    Purity:98.91% - 99.92%
    Color and Shape:Solid
    Molecular weight:507.499
  • FIPI HCl

    CAS:
    <p>FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.</p>
    Formula:C23H25ClFN5O2
    Color and Shape:Solid
    Molecular weight:457.93
  • Schisandrol B

    CAS:
    <p>Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.</p>
    Formula:C23H28O7
    Purity:99.14% - 99.95%
    Color and Shape:Solid
    Molecular weight:416.46
  • Lapatinib tosylate

    CAS:
    <p>Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) &amp; 9.8 nM (ErbB-2).</p>
    Formula:C36H34ClFN4O7S2
    Color and Shape:Solid
    Molecular weight:753.26
  • Brefeldin A

    CAS:
    <p>Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).</p>
    Formula:C16H24O4
    Purity:96.45% - 99.89%
    Color and Shape:White Solid
    Molecular weight:280.36
  • Sanguinarine

    CAS:
    <p>Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.</p>
    Formula:C20H14NO4
    Purity:99.04% - 99.76%
    Color and Shape:Solid
    Molecular weight:332.33
  • Idarubicin

    CAS:
    <p>Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.</p>
    Formula:C26H27NO9
    Color and Shape:Solid
    Molecular weight:497.49
  • FIPI

    CAS:
    <p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>
    Formula:C23H24FN5O2
    Purity:97.21% - 98.68%
    Color and Shape:Solid
    Molecular weight:421.47
  • MRT68921 HCl

    CAS:
    <p>MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).</p>
    Formula:C25H34N6O·HCl
    Purity:99.86% - 99.98%
    Color and Shape:Solid
    Molecular weight:471.04
  • ABT-737

    CAS:
    <p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>
    Formula:C42H45ClN6O5S2
    Purity:98.15% - >99.99%
    Color and Shape:Solid
    Molecular weight:813.43
  • Dinoprost tromethamine salt

    CAS:
    <p>Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.</p>
    Formula:C24H45NO8
    Purity:99.73%
    Color and Shape:Natural Form Crystals Solid
    Molecular weight:475.62
  • Calcimycin

    CAS:
    <p>Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.</p>
    Formula:C29H37N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:523.62
  • Sophocarpine

    CAS:
    <p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>
    Formula:C15H22N2O
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:246.35
  • Fasudil hydrochloride hydrate

    CAS:
    <p>Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.</p>
    Formula:C28H38Cl2N6O5S2
    Color and Shape:Solid
    Molecular weight:673.67
  • Oprozomib

    CAS:
    <p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>
    Formula:C25H32N4O7S
    Purity:98% - 99.87%
    Color and Shape:Solid
    Molecular weight:532.61
  • Paris saponin VII

    CAS:
    <p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>
    Formula:C51H82O21
    Purity:99.51% - 99.63%
    Color and Shape:Solid
    Molecular weight:1031.18
  • Quercitrin

    CAS:
    <p>Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.</p>
    Formula:C21H20O11
    Purity:98.89% - 99.66%
    Color and Shape:Yellow Crystals From Dil Methanol Or Ethanol Solid
    Molecular weight:448.38
  • Everolimus

    CAS:
    <p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>
    Formula:C53H83NO14
    Purity:97.76% - 99.78%
    Color and Shape:Off-White To Light Yellow Powd
    Molecular weight:958.22
  • Vandetanib

    CAS:
    <p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>
    Formula:C22H24BrFN4O2
    Purity:99.7% - >99.99%
    Color and Shape:White Solid
    Molecular weight:475.35
  • Nutlin-3a

    CAS:
    <p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C30H30Cl2N4O4
    Purity:95.62% - 99.71%
    Color and Shape:Solid
    Molecular weight:581.49
  • PD168393

    CAS:
    <p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>
    Formula:C17H13BrN4O
    Purity:99.13% - 99.83%
    Color and Shape:Solid
    Molecular weight:369.22
  • Schisandrin

    CAS:
    <p>Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.</p>
    Formula:C24H32O7
    Purity:98.97% - 99.32%
    Color and Shape:White Powder
    Molecular weight:432.51
  • NS1643

    CAS:
    <p>NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.</p>
    Formula:C15H10F6N2O3
    Purity:98.37% - 99.31%
    Color and Shape:Solid
    Molecular weight:380.24
  • GLPG1837

    CAS:
    <p>GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.</p>
    Formula:C16H20N4O3S
    Purity:99.64% - 99.91%
    Color and Shape:Solid
    Molecular weight:348.42
  • DPN

    CAS:
    <p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>
    Formula:C15H13NO2
    Purity:99.01%
    Color and Shape:Off-White Solid
    Molecular weight:239.27
  • Tacrolimus monohydrate

    CAS:
    <p>Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.</p>
    Formula:C44H71NO13
    Purity:97.07% - 98.05%
    Color and Shape:Solid
    Molecular weight:822.05
  • UBCS039

    CAS:
    <p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>
    Formula:C16H13N3
    Purity:98.31%
    Color and Shape:Solid
    Molecular weight:247.29
  • Capivasertib

    CAS:
    <p>Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.</p>
    Formula:C21H25ClN6O2
    Purity:97.59% - 99.6%
    Color and Shape:Solid
    Molecular weight:428.92
  • Carbamazepine

    CAS:
    <p>Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.</p>
    Formula:C15H12N2O
    Purity:99.78% - 99.79%
    Color and Shape:Solid
    Molecular weight:236.27