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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1424 products of "Autophagy"

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  • Glucosamine hydrochloride

    CAS:
    <p>Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.</p>
    Formula:C6H13NO5·HCl
    Purity:99.77%
    Color and Shape:White Solid Crystalline
    Molecular weight:215.63
  • Fluvastatin sodium

    CAS:
    <p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>
    Formula:C24H25FNNaO4
    Purity:98.54% - 99.56%
    Color and Shape:Light Yellow Solid Powder
    Molecular weight:433.45
  • Reserpine

    CAS:
    <p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>
    Formula:C33H40N2O9
    Purity:98.85% - 99.81%
    Color and Shape:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)
    Molecular weight:608.68
  • BIX 02565

    CAS:
    <p>BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).</p>
    Formula:C26H30N6O2
    Purity:97.44% - 99.7%
    Color and Shape:Solid
    Molecular weight:458.56
  • Erlotinib hydrochloride

    CAS:
    <p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>
    Formula:C22H23N3O4·HCl
    Purity:99.78% - 99.85%
    Color and Shape:White Or Off-White Powder
    Molecular weight:429.9
  • Dihydroartemisinin

    CAS:
    <p>Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!</p>
    Formula:C15H24O5
    Purity:98% - 99.41%
    Color and Shape:White Solid
    Molecular weight:284.35
  • Imatinib Mesylate

    CAS:
    <p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>
    Formula:C29H31N7O·CH4SO3
    Purity:98% - >99.99%
    Color and Shape:White Crystalline Powder
    Molecular weight:589.71
  • Lapatinib ditosylate monohydrate

    CAS:
    <p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>
    Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2O
    Purity:98% - 99.41%
    Color and Shape:Colourless To Light-Yellow Crystal
    Molecular weight:943.47
  • Carvedilol phosphate hemihydrate

    CAS:
    <p>Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.</p>
    Formula:C24H26N2O4·5H2O·H3O4P
    Purity:99.24% - 99.98%
    Color and Shape:Solid
    Molecular weight:513.49
  • 9-ING-41

    CAS:
    <p>9-ING-41 is a glycogen synthase kinase-3 inhibitor.</p>
    Formula:C22H13FN2O5
    Purity:99.32%
    Color and Shape:Solid
    Molecular weight:404.35
  • Raloxifene hydrochloride

    CAS:
    <p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>
    Formula:C28H28ClNO4S
    Purity:98% - 99.97%
    Color and Shape:Light Yellow Solid
    Molecular weight:510.044
  • ZX-29

    CAS:
    <p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>
    Formula:C23H28ClN7O3S
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:518.03
  • Tranexamic acid

    CAS:
    <p>Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.</p>
    Formula:C8H15NO2
    Purity:99.64% - 99.79%
    Color and Shape:White Crystalline Powder
    Molecular weight:157.21
  • Sinomenine hydrochloride

    CAS:
    <p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>
    Formula:C19H24ClNO4
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:365.851
  • Quetmolimab

    CAS:
    <p>Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis.</p>
    Purity:SDS-PAGE:95% SEC-HPLC:97.59%
    Color and Shape:Liquid
    Molecular weight:150 kDa
  • Daunorubicin hydrochloride

    CAS:
    <p>Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein</p>
    Formula:C27H29NO10·HCl
    Purity:96.21% - 99.53%
    Color and Shape:Cancer Drug
    Molecular weight:563.99
  • Erlotinib

    CAS:
    <p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>
    Formula:C22H23N3O4
    Purity:98.19% - 99.98%
    Color and Shape:White To Off-White Powder
    Molecular weight:393.44
  • Baicalin

    CAS:
    <p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>
    Formula:C21H18O11
    Purity:90.08% - 99.32%
    Color and Shape:Yellow Powder
    Molecular weight:446.36
  • Ambroxol

    CAS:
    <p>Ambroxol treats respiratory diseases by thinning mucus. Active in Mucosolvan, it enhances mucus clearance and protects lungs.</p>
    Formula:C13H18Br2N2O
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:378.1
  • Eldelumab

    CAS:
    <p>Eldelumab (BMS-936557) is an anti-IP-10 IgG 1 monoclonal antibody.Eldelumab has anti-inflammatory activity and is used to study rheumatoid arthritis.</p>
    Purity:95%
    Color and Shape:Liquid
  • Sophocarpine monohydrate

    CAS:
    <p>Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>
    Formula:C15H22N2O
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:246.35
  • Rimantadine hydrochloride

    CAS:
    <p>Rimantadine hydrochloride (Meradane) is an RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.</p>
    Formula:C12H21N·HCl
    Purity:99.47% - 99.85%
    Color and Shape:White Crystalline Solid
    Molecular weight:215.76
  • Clioquinol

    CAS:
    <p>Clioquinol: oral, lipophilic copper-binder; halogenated quinoline with antifungal, antiparasitic, and possible antitumor uses.</p>
    Formula:C9H5ClINO
    Purity:97.02%
    Color and Shape:Brownish-Yellow Bulky Powder Decomposes At 178-179°C Used As A Topical Anti-Infective
    Molecular weight:305.5
  • Sulfacetamide sodium

    CAS:
    <p>Sulfacetamide sodium (Sulamyd sodium) is an anti-infective agent. It is used topically to treat orally for urinary tract infections and skin infections.</p>
    Formula:C8H9N2NaO3S
    Purity:99.90% - 99.96%
    Color and Shape:White Crystalline Powder
    Molecular weight:236.22
  • Vitamin B3-d4

    CAS:
    <p>Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is a deuterated substitute for Niacin and can be used to track Niacin metabolism in vivo.</p>
    Formula:C6HD4NO2
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:127.13
  • Ponatinib Hydrochloride

    CAS:
    <p>Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib.</p>
    Formula:C29H28ClF3N6O
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:569.02
  • Dexamethasone

    CAS:
    <p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>
    Formula:C22H29FO5
    Purity:98% - 99.91%
    Color and Shape:Crystals From Ether (Ntp 1992)
    Molecular weight:392.46
  • Amiodarone hydrochloride

    CAS:
    <p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>
    Formula:C25H29I2NO3·HCl
    Purity:99.82% - ≥95%
    Color and Shape:White To Cream Crystalline Powder
    Molecular weight:681.78
  • Dexamethasone acetate

    CAS:
    <p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>
    Formula:C24H31FO6
    Purity:99.22% - 99.65%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:434.50
  • Phenformin hydrochloride

    CAS:
    <p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>
    Formula:C10H16ClN5
    Purity:97.11% - 99.80%
    Color and Shape:Lactic Acidosis
    Molecular weight:241.72
  • Mevastatin

    CAS:
    <p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>
    Formula:C23H34O5
    Purity:99.12%
    Color and Shape:White-Yellowish To Yellow Powder Solid Powder
    Molecular weight:390.51
  • Avermectin B1

    CAS:
    <p>Avermectin B1 is served as anthelmintic and insecticide.</p>
    Formula:C48H72O14
    Purity:mixture - mixture
    Color and Shape:White Powder
    Molecular weight:873.09
  • Cytarabine

    CAS:
    <p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>
    Formula:C9H13N3O5
    Purity:99.83% - 99.93%
    Color and Shape:Fine Off-White Crystalline Powder
    Molecular weight:243.22
  • Lomustine

    CAS:
    <p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>
    Formula:C9H16ClN3O2
    Purity:98.36% - 99.44%
    Color and Shape:Solid Solid
    Molecular weight:233.7
  • Crustecdysone

    CAS:
    <p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>
    Formula:C27H44O7
    Purity:99.06% - 99.67%
    Color and Shape:Canary Yellow Fine Powder
    Molecular weight:480.63
  • Silmitasertib sodium salt

    CAS:
    <p>Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).</p>
    Formula:C19H11ClN3NaO2
    Purity:99.49% - 99.62%
    Color and Shape:Solid
    Molecular weight:371.75
  • Nicardipine hydrochloride

    CAS:
    <p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>
    Formula:C26H30ClN3O6
    Purity:99.58% - 99.89%
    Color and Shape:Yellow Solid
    Molecular weight:515.99
  • NBDHEX

    CAS:
    <p>NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).</p>
    Formula:C12H15N3O4S
    Purity:97.38%
    Color and Shape:Solid
    Molecular weight:297.33
  • AZD7624

    CAS:
    <p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>
    Formula:C27H30FN5O3
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:491.56
  • Carboplatin

    CAS:
    <p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>
    Formula:C6H12N2O4Pt
    Purity:98% - 99.72%
    Color and Shape:White Crystalline Powder
    Molecular weight:371.25
  • Matrine

    CAS:
    <p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>
    Formula:C15H24N2O
    Purity:97.16% - >99.99%
    Color and Shape:Solid
    Molecular weight:248.36
  • Paclitaxel

    CAS:
    <p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>
    Formula:C47H51NO14
    Purity:98% - 99.92%
    Color and Shape:White Powder
    Molecular weight:853.91
  • Oxaliplatin

    CAS:
    <p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>
    Formula:C8H14N2O4Pt
    Purity:97% - 99.93%
    Color and Shape:Solid
    Molecular weight:397.29
  • Sunitinib Malate

    CAS:
    <p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>
    Formula:C26H33FN4O7
    Purity:98% - 99.26%
    Color and Shape:Solid
    Molecular weight:532.56
  • Rhein

    CAS:
    <p>Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.</p>
    Formula:C15H8O6
    Purity:99.04%
    Color and Shape:Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)
    Molecular weight:284.22
  • Vancomycin hydrochloride

    CAS:
    <p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>
    Formula:C66H76Cl3N9O24
    Purity:97.20% - 99.19%
    Color and Shape:Off White Powder
    Molecular weight:1485.71
  • Doxazosin mesylate

    CAS:
    <p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>
    Formula:C24H29N5O8S
    Purity:99.92%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:547.58
  • Memantine hydrochloride

    CAS:
    <p>Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.</p>
    Formula:C12H22ClN
    Purity:99.56% - 99.96%
    Color and Shape:Crystalline Solid
    Molecular weight:215.76
  • TTNPB

    CAS:
    <p>TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),</p>
    Formula:C24H28O2
    Purity:99.55%
    Color and Shape:White Solid
    Molecular weight:348.48
  • Amoxapine

    CAS:
    <p>Amoxapine (CL-67772) exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve</p>
    Formula:C17H16ClN3O
    Purity:98.25% - 98.80%
    Color and Shape:Solid
    Molecular weight:313.78