GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 19 more subcategories

Found 5838 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

+ Info
Pasireotide
CAS:
- 396091-73-9
Pasireotide (SOM 230) is a cyclohexapeptide, mimicking somatostatin with high affinity for sst1/2/3/4/5 receptors (pKi=8.2/9.0/9.1/<7.0/9.9).
Formula:C₅₈H₆₆N₁₀O₉
Purity:98%
Color and Shape:Solid
Molecular weight:1047.21
Ref: TM-T12370
+ Info
MAO-B-IN-3
MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki
Formula:C₂₄H₂₅N₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:387.47
Ref: TM-T78648
+ Info
des-Gln14-Ghrelin TFA
Des-Gln14-Ghrelin TFA, a ligand for GHSR, boosts [Ca2+]i with an EC50 of 2.4 nM in CHO-GHSR62 cells.
Formula:C₁₄₄H₂₃₈F₃N₄₃O₄₂
Color and Shape:Solid
Molecular weight:3300.69
Ref: TM-T75928
+ Info
Tirzepatide TFA
Tirzepatide TFA, a GIP and GLP-1 agonist, targets type 2 diabetes treatment.
Formula:C₂₂₇H₃₄₉F₃N₄₈O₇₀
Color and Shape:Solid
Molecular weight:4927.47
Ref: TM-T76006
+ Info
Stressin I
Potent CRF1 agonist; Ki: 1.5 nM (CRF1), 224 nM (CRF2). Boosts ACTH, enhances stool frequency after i.p. administration.
Formula:C₂₀₃H₃₃₇N₅₇O₅₆
Purity:98%
Color and Shape:Solid
Molecular weight:4472.24
Ref: TM-TP2125
+ Info
[Ala11,D-Leu15]-Orexin B(human)
CAS:
- 532932-99-3
OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).
Formula:C₁₂₀H₂₀₆N₄₄O₃₅S
Purity:98%
Color and Shape:Solid
Molecular weight:2857.28
Ref: TM-TP1975
+ Info
Filimelnotide
CAS:
- 2093087-54-6
Filimelnotide is an agonist of the melanocortin receptor.
Formula:C₄₇H₆₉N₁₅O₉S₂
Color and Shape:Solid
Molecular weight:1052.28
Ref: TM-TP3737
+ Info
α-CGRP(human)
CAS:
- 90954-53-3
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.
Formula:C₁₆₃H₂₆₇N₅₁O₄₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3789.33
Ref: TM-TP2044
+ Info
SGLT1/2-IN-2
CAS:
- 2387812-73-7
SGLT1/2-IN-2 is a chemical compound with robust dual inhibitory properties, exhibiting potent activities against SGLT1 (IC50 = 96 nM) and SGLT2 (IC50 = 1.3 nM).
Formula:C₂₃H₂₆F₂O₇
Color and Shape:Solid
Molecular weight:452.451
Ref: TM-T39966
+ Info
α-Helical CRF(9-41)
CAS:
- 90880-23-2
Corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively).
Formula:C₁₆₆H₂₇₄N₄₆O₅₃S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3827
Ref: TM-TP2048
+ Info
AGN 191976
CAS:
- 159359-94-1
AGN 191976 is a novel thromboxane A2-mimetic.
Formula:C₂₁H₃₂O₆
Color and Shape:Solid
Molecular weight:380.481
Ref: TM-T29722
+ Info
Zoliprofen
CAS:
- 56355-17-0
Zoliprofen: potent, oral NSAID with anti-inflammatory, antipyretic, analgesic effects. Exceeds ibuprofen's efficacy in rats and rabbits.
Formula:C₁₂H₁₁NO₃S
Purity:99.62%
Color and Shape:Solid
Molecular weight:249.29
Ref: TM-T68025
+ Info
Angiopeptin TFA
CAS:
- 2478421-60-0
Angiopeptin TFA: somatostatin analogue, sst2/sst5 partial agonist (IC50: 0.26/6.92 nM), suppresses GH & IGF-1, for atherosclerosis research.
Formula:C₅₈H₇₃F₆N₁₁O₁₄S₂
Color and Shape:Solid
Molecular weight:1326.39
Ref: TM-T76042
+ Info
Antisauvagine-30
CAS:
- 220673-95-0
CRF2 receptor antagonist; Kd 1.4 nM (mCRF2β), 153.6 nM (rCRF1). Blocks sauvagine-induced cAMP in cells & stress-related responses in mice.
Formula:C₁₆₁H₂₇₄N₄₈O₄₆S
Purity:98%
Color and Shape:Solid
Molecular weight:3650.29
Ref: TM-TP2091
+ Info
(+)-Cloprostenol
CAS:
- 54276-21-0
(+)-Cloprostenol is a analogue of prostaglandin F2α (PGF2α), and is selective prostaglandin receptor agonistic.
Formula:C₂₂H₂₉ClO₆
Purity:98%
Color and Shape:Solid
Molecular weight:424.92
Ref: TM-T13461
+ Info
Spns2-IN-2
Spns2-IN-2 (compound 3a) is an inhibitor of SPNS2.
Formula:C₂₂H₃₀ClN₃O₂
Color and Shape:Solid
Molecular weight:403.95
Ref: TM-T200979
+ Info
Amylin (8-37), human
CAS:
- 135702-23-7
Human-derived Amylin (8-37) is a vasodilator in rat arteries and forms aggregates linked to type II diabetes.
Formula:C₁₃₈H₂₁₆N₄₂O₄₅
Color and Shape:Solid
Molecular weight:3183.495
Ref: TM-T38764
+ Info
Neuropeptide Y (13-36), amide, human
CAS:
- 122341-40-6
Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.
Formula:C₁₃₄H₂₀₇N₄₁O₃₆S
Purity:98%
Color and Shape:Solid
Molecular weight:3000.4
Ref: TM-TP1081
+ Info
OXA(17-33) TFA
OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).
Formula:C₈₁H₁₂₆F₃N₂₃O₂₄
Color and Shape:Solid
Molecular weight:1863
Ref: TM-T75922
+ Info
MK-7246 S enantiomer
MK-7246 S enantiomer is a potent and selective CRTH2 antagonist.
Formula:C₂₁H₂₁FN₂O₄S
Purity:98%
Color and Shape:Solid
Molecular weight:416.47
Ref: TM-T12067
+ Info
Dexbrompheniramine
CAS:
- 132-21-8
Dexbrompheniramine: oral H1 antagonist, antihistamine for hay fever and urticaria research.
Formula:C₁₆H₁₉BrN₂
Color and Shape:Solid
Molecular weight:319.24
Ref: TM-T75276
+ Info
Icatibant
CAS:
- 130308-48-4
Icatibant is a selective and specific antagonist of the bradykinin B2 receptor (IC50 and Ki: 1.07 nM and 0.798 nM respectively).
Formula:C₅₉H₈₉N₁₉O₁₃S
Purity:98%
Color and Shape:White Solid
Molecular weight:1304.52
Ref: TM-T15547
+ Info
Dulaglutide
CAS:
- 923950-08-7
Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).
Color and Shape:Solid
Ref: TM-T75718
+ Info
RF9 acetate
RF9 acetate is an effective and selective antagonist of Neuropeptide FF receptor with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.
Formula:C₂₈H₄₂N₆O₅
Purity:99.77%
Color and Shape:Solid
Molecular weight:542.67
Ref: TM-T16738L
+ Info
P2Y6R antagonist 1
P2Y6R antagonist 1 (compound 5ab) is a selective, orally active antagonist of P2Y6R, featuring an IC50 value of 19.6 nM. This compound also exhibits anti-inflammatory properties.
Color and Shape:Odour Solid
Ref: TM-T200515
+ Info
Methdilazine
CAS:
- 1982-37-2
Methdilazine: oral antibiotic, histamine antagonist, fights mycobacterium (MIC 5-15 μg/mL) for infectious disease research.
Formula:C₁₈H₂₀N₂S
Color and Shape:Solid
Molecular weight:296.43
Ref: TM-T75313
+ Info
d[Cha4]-AVP TFA
d[Cha4]-AVP TFA: potent, selective V1b agonist, K i 1.2 nM, favors V1b over V1a, V2, oxytocin receptors.
Formula:C₅₂H₇₂F₃N₁₃O₁₃S₂
Color and Shape:Solid
Molecular weight:1208.33
Ref: TM-T75933
+ Info
(Pro34)-Peptide YY (human)
CAS:
- 179986-93-7
(Pro34)-Peptide YY (human) is a highly Y 1 -selective full agonist of Peptide YY /neuropeptide Y receptors [1] .
Formula:C₁₉₄H₂₉₄N₅₄O₅₆
Color and Shape:Solid
Molecular weight:4278.73
Ref: TM-T76441
+ Info
HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.
Color and Shape:Odour Solid
Ref: TM-T200554
+ Info
Cortistatin 14, human, rat
CAS:
- 193829-96-8
Cortistatin 14: a neuropeptide similar to somatostatin; induces sleep, depresses neuronal activity; found in cortex, hippocampus.
Formula:C₈₁H₁₁₃N₁₉O₁₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1721.01
Ref: TM-TP1188
+ Info
Adrenomedullin (16-31), human TFA
Human adrenomedullin (16-31) TFA, fragment 16-31, binds CGRP1 receptor, raises rat blood pressure, not cats’.
Formula:C₈₄H₁₃₀F₃N₂₅O₂₃S₂
Color and Shape:Solid
Molecular weight:1979.21
Ref: TM-T76011
+ Info
BAY-747
CAS:
- 1609342-18-8
BAY-747: oral, brain-penetrant sGC stimulator; improves rat memory, cognition, lowers blood pressure, aids Duchenne muscular dystrophy.
Formula:C₂₂H₂₆F₂N₄O₂
Color and Shape:Solid
Molecular weight:416.46
Ref: TM-T75137
+ Info
Adrenocorticotropic Hormone (ACTH) (1-39), rat
CAS:
- 77465-10-2
ACTH (1-39), rat: potent MC2 agonist, forms fragments in vitro, isolated by HPLC, characterized by amino acids and NH2-terminus.
Formula:C₂₁₀H₃₁₅N₅₇O₅₇S
Purity:98%
Color and Shape:Solid
Molecular weight:4582.23
Ref: TM-TP1249
+ Info
PACAP (1-27), human, ovine, rat
CAS:
- 127317-03-7
PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.
Formula:C₁₄₂H₂₂₄N₄₀O₃₉S
Purity:98%
Color and Shape:Solid
Molecular weight:3147.66
Ref: TM-TP1070
+ Info
Apelin-36(human)
CAS:
- 252642-12-9
Endogenous APJ agonist, EC50=20nM, regulates cardiovascular function, fluid balance, and feeding; blocks certain HIV strains.
Formula:C₁₈₄H₂₉₇N₆₉O₄₃S
Purity:98%
Color and Shape:Solid
Molecular weight:4195.87
Ref: TM-TP2093
+ Info
CCG258208 hydrochloride
GRKs-IN-1 HCl (14as) strongly inhibits GRK2 (IC50=130nM) & GRK5 (IC50=7.1μM), is a paroxetine derivative with 100x cardiac boost.
Color and Shape:Solid
Ref: TM-T35875
+ Info
Syk Inhibitor II hydrochloride
CAS:
- 2490508-82-0
Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.
Formula:C₁₄H₁₆ClF₃N₆O
Purity:99.05%
Color and Shape:Solid
Molecular weight:376.77
Ref: TM-T9543
+ Info
8-iso-15-keto Prostaglandin F2α
CAS:
- 191919-01-4
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans.
Formula:C₂₀H₃₂O₅
Color and Shape:Solid
Molecular weight:352.471
Ref: TM-T36166
+ Info
Dipentylone hydrochloride
CAS:
- 17763-13-2
Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.
Formula:C₁₄H₂₀ClNO₃
Purity:99.94%
Color and Shape:Solid
Molecular weight:285.77
Ref: TM-T205977
+ Info
CB1R agonist 1
CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.
Formula:C₂₀H₁₈F₃N₃O₃S
Color and Shape:Solid
Molecular weight:437.435
Ref: TM-T206337
+ Info
Cortistatin 14, human, rat acetate
Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and
Formula:C₈₀H₁₁₂N₁₈O₁₉S₂
Purity:97.86%
Color and Shape:Solid
Molecular weight:1693.98
Ref: TM-TP1188L
+ Info
GI-560192
CAS:
- 301326-41-0
GI-560192 (RL-0070933), a potent smo modulator, EC50: 0.02µM; affects smoothened in cilia via hedgehog signaling.
Formula:C₂₀H₁₆N₂O₂
Purity:99.53%
Color and Shape:Soild
Molecular weight:316.35
Ref: TM-T64351
+ Info
β2AR/M-receptor agonist-1
CAS:
- 2230520-62-2
β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and
Formula:C₄₃H₅₆BrN₃O₇
Color and Shape:Solid
Molecular weight:806.82
Ref: TM-T74708
+ Info
Orexin B, rat, mouse TFA
Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.
Formula:C₁₂₈H₂₁₆F₃N₄₅O₃₆S
Color and Shape:Solid
Molecular weight:3050.42
Ref: TM-T75925
+ Info
Selank
CAS:
- 129954-34-3
Selank is a synthetic analog of tuftsin.
Formula:C₃₃H₅₇N₁₁O₉
Purity:98%
Color and Shape:Solid
Molecular weight:751.87
Ref: TM-T20515
+ Info
11-deoxy Prostaglandin E2
CAS:
- 35536-53-9
11-deoxy PGE2 is a synthetic PGE2 analog, a potent bronchoconstrictor, 5-30x stronger than PGF2α on human respiratory muscles.
Formula:C₂₀H₃₂O₄
Color and Shape:Solid
Molecular weight:336.47
Ref: TM-T38342
+ Info
Eletriptan
CAS:
- 143322-58-1
Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.
Formula:C₂₂H₂₆N₂O₂S
Color and Shape:Solid
Molecular weight:382.52
Ref: TM-T0216L
+ Info
DSP-1053
CAS:
- 1176326-76-3
Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.
Formula:C₂₆H₃₂BrNO₄
Purity:98%
Color and Shape:Solid
Molecular weight:502.44
Ref: TM-T11107
+ Info
Preclamol hydrochloride
CAS:
- 88768-67-6
Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.
Formula:C₁₄H₂₂ClNO
Color and Shape:Solid
Molecular weight:255.78
Ref: TM-T73684
+ Info
[Nle11]-Substance P
CAS:
- 57462-42-7
'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'
Formula:C₆₄H₁₀₀N₁₈O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1329.59
Ref: TM-TP1831
+ Info
(±)5-iPF2α-VI
CAS:
- 179094-11-2
Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation.
Formula:C₂₀H₃₄O₅
Color and Shape:Solid
Molecular weight:354.487
Ref: TM-T36605
+ Info
QWF
CAS:
- 126088-82-2
Tripeptide SP antagonist (IC50: 90 μM); blocks SP-MRGPR X2 binding and mast cell degranulation; reduces 48/80-induced scratching in mice.
Formula:C₃₈H₄₃N₅O₈
Purity:98%
Color and Shape:Solid
Molecular weight:697.78
Ref: TM-TP1946
+ Info
VIP36
VIP36 is an agonist of the cannabinoid type 1 receptor (CB1) with analgesic properties. It reduces the recruitment of inhibitory proteins, thereby exerting its pain-relieving effects, and is applicable in research related to chronic pain.
Formula:C₂₇H₃₅FN₆O₄
Color and Shape:Solid
Molecular weight:526.603
Ref: TM-T206705
+ Info
Ghrelin receptor full agonist-2
CAS:
- 2602452-73-1
Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist.
Formula:C₂₆H₂₈ClN₅O₅S
Color and Shape:Solid
Molecular weight:558.05
Ref: TM-T40234
+ Info
Chemerin-9, Mouse
CAS:
- 686324-96-9
Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156.
Formula:C₅₁H₆₈N₁₀O₁₂
Color and Shape:Solid
Molecular weight:1013.163
Ref: TM-T37128
+ Info
(3R,5R,6S)-Atogepant
(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.
Formula:C₂₉H₂₃F₆N₅O₃
Color and Shape:Solid
Molecular weight:603.52
Ref: TM-T73703
+ Info
S 16474
CAS:
- 149250-10-2
S 16474 is an antagonist of Neurokinin-1 Receptor.
Formula:C₄₄H₄₈N₆NaO₈
Purity:98%
Color and Shape:Solid
Molecular weight:811.892
Ref: TM-T26169
+ Info
GRL018-21
GRL018-21 is a potent, highly selective inhibitor of G protein-coupled receptor kinase 5 (GRK5), exhibiting an IC50 of 10 nM [1].
Color and Shape:Odour Solid
Ref: TM-T82258
+ Info
Urocortin III (human)
CAS:
- 357952-09-1
Urocortin III, a human peptide, binds CRF-R2, affecting insulin via somatostatin feedback with K i values 13.5-100+ nM.
Formula:C₁₈₅H₃₀₇N₅₃O₅₀S₂
Color and Shape:Solid
Molecular weight:4137.93
Ref: TM-T76180
+ Info
Glucagon-like peptide 1 (1-37), human
CAS:
- 87805-34-3
Human GLP-1 (1-37) is a potent GLP-1 receptor agonist without impact on rat food intake or insulin secretion.
Formula:C₁₈₆H₂₇₅N₅₁O₅₉
Purity:98%
Color and Shape:Solid
Molecular weight:4169.48
Ref: TM-TP1148
+ Info
INCB 3284 dimesylate
CAS:
- 887401-93-6
INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.
Formula:C₂₈H₃₉F₃N₄O₁₀S₂
Purity:98%
Color and Shape:Solid
Molecular weight:712.76
Ref: TM-T11647
+ Info
12-epi Leukotriene B4
CAS:
- 83709-73-3
LTB4 is made enzymatically (12(R)-specific) and non-enzymatically (6-trans-12-epi mix). 12-epi LTB4 has low receptor activity.
Formula:C₂₀H₃₂O₄
Color and Shape:Solid
Molecular weight:336.472
Ref: TM-T37970
+ Info
Imelciment
CAS:
- 2845128-03-0
Imelciment (REGN-9035) is a humanised monoclonal antibody targeting NPR1, which can be used for research into heart failure.
Purity:95%
Color and Shape:Soild
Ref: TM-T9901A-366
+ Info
Protease-Activated Receptor-1 antagonist 2
CAS:
- 1454588-34-1
Orally active PAR-1 antagonist with 7 nM IC50; potential for CVD research.
Formula:C₂₄H₂₃F₂N₃O₂
Color and Shape:Solid
Molecular weight:423.46
Ref: TM-T74266
+ Info
Adrenomedullin (16-31), human
CAS:
- 318480-38-5
Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).
Formula:C₈₂H₁₂₉N₂₅O₂₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1865.19
Ref: TM-TP1486
+ Info
Chir 2279
CAS:
- 158198-45-9
CHIR 2279, a peptoid trimer, binds alpha 1-adrenoceptors, blocking epinephrine effects in dogs (pseudo pA2 6.86).
Formula:C₃₄H₃₆N₄O₄
Color and Shape:Solid
Molecular weight:564.67
Ref: TM-T30880
+ Info
PSB 0777 ammonium salt
CAS:
- 2122196-16-9
adenosine A2A receptor full agonist
Formula:C₁₈H₂₄N₆O₇S₂
Purity:98%
Color and Shape:Solid
Molecular weight:500.55
Ref: TM-T23196
+ Info
Cannabidiolic acid methyl ester
CAS:
- 55658-71-4
Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.
Formula:C₂₃H₃₂O₄
Color and Shape:Solid
Molecular weight:372.5
Ref: TM-T203571
+ Info
CB2R probe 1
CAS:
- 2634714-79-5
CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of
Formula:C₃₆H₄₂N₄O₄
Color and Shape:Solid
Molecular weight:594.74
Ref: TM-T74604
+ Info
Prostaglandin F1α
CAS:
- 745-62-0
Prostaglandin F1α (PGF1α) is a lipid mediator and an endogenous metabolite of prostacyclin, regulate smooth muscle contraction.
Formula:C₂₀H₃₆O₅
Color and Shape:Solid
Molecular weight:356.5
Ref: TM-T37919
+ Info
L-threo Lysosphingomyelin (d18:1)
CAS:
- 105615-55-2
L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).
Formula:C₂₃H₄₉N₂O₅P
Color and Shape:Solid
Molecular weight:464.62
Ref: TM-T38452
+ Info
12(S)-HpEPE
CAS:
- 103239-14-1
12(S)-HpEPE, a fatty acid created by 12-lipoxygenase on EPA, has unclear biological activities but may resemble 12(S)-HpETE.
Formula:C₂₀H₃₀O₄
Color and Shape:Solid
Molecular weight:334.456
Ref: TM-T37968
+ Info
Poly-D-lysine hydrobromide (MW 1000-5000)
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.
Color and Shape:Odour Solid
Ref: TM-TCL-01108
+ Info
LAS190792
CAS:
- 1347232-69-2
LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.
Formula:C₃₉H₄₃ClN₄O₉S₂
Color and Shape:Solid
Molecular weight:811.36
Ref: TM-T74709
+ Info
Cenderitide
CAS:
- 507289-11-4
Cenderitide fuses CNP with DNP, stimulates pGC-A/B, ups cGMP, curbs aldosterone, and aids GFR, not affecting BP—used in heart failure studies.
Formula:C₁₅₈H₂₆₃N₄₉O₅₀S₃
Color and Shape:Solid
Molecular weight:3745.27
Ref: TM-T76334
+ Info
[Gly8]-GLP-1(7-37) acetate
[Gly8]-GLP-1(7-37) acetate is a derivative of GLP-1, where glycine at position 8 is replaced with alanine. [Gly8]-GLP-1(7-37) acetate is also a peptide fragment of the GLP-1 receptor (GLP-1R) agonist, Dulaglutide.
Color and Shape:Odour Solid
Ref: TM-TP3691
+ Info
D5R agonist 1
D5R Agonist 1 (Compound 5j) is a selective, orally active partial agonist of the D5 receptor that can penetrate the blood-brain barrier (EC50: 269.7 nM). It has been demonstrated to enhance cognitive abilities in a scopolamine-induced amnesia model.
Color and Shape:Odour Solid
Ref: TM-T200501
+ Info
Haloperidol D4
CAS:
- 1189986-59-1
Haloperidol D4 is deuterium-labeled haloperidol.
Formula:C₂₁H₂₃ClFNO₂
Purity:98%
Color and Shape:Solid
Molecular weight:379.89
Ref: TM-T11535
+ Info
[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
CAS:
- 118122-39-7
Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.
Formula:C₅₀H₇₅N₁₅O₁₀
Purity:98%
Color and Shape:Solid
Molecular weight:1046.23
Ref: TM-TP2076
+ Info
Efranarelaxin alfa
CAS:
- 2969217-22-7
Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.
Color and Shape:Liquid
Ref: TM-T9901A-865
+ Info
Vortioxetine D8
CAS:
- 2140316-62-5
Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).
Formula:C₁₈H₂₂N₂S
Purity:98%
Color and Shape:Solid
Molecular weight:306.5
Ref: TM-T13308
+ Info
GLP-1R agonist 15
CAS:
- 2763621-11-8
GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .
Formula:C₄₆H₄₇FN₈O₇S
Color and Shape:Solid
Molecular weight:874.98
Ref: TM-T74609
+ Info
Poly-D-lysine hydrobromide (MW 150000-300000)
Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.
Color and Shape:Odour Solid
Ref: TM-TCL-01090
+ Info
Sauvagine TFA
Sauvagine TFA: frog-derived, 40-amino-acid CRF agonist; stimulates ACTH release, affects diuresis, cardiovascular system, endocrine glands.
Formula:C₂₀₄H₃₄₇F₃N₅₆O₆₅S₁
Color and Shape:Solid
Molecular weight:4713.33
Ref: TM-T75894
+ Info
FR 113680
CAS:
- 126088-92-4
FR 113680 is a tripeptide substance P antagonist with NK1 receptor selectivity.
Formula:C₃₅H₃₉N₅O₆
Purity:98%
Color and Shape:Solid
Molecular weight:625.726
Ref: TM-T27360
+ Info
Leukotriene B4 Ethanolamide
CAS:
- 877459-63-7
LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.
Formula:C₂₂H₃₇NO₄
Color and Shape:Solid
Molecular weight:379.541
Ref: TM-T37619
+ Info
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
CAS:
- 68059-94-9
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a synthetic LHRH analog and a GnRH receptor antagonist.
Formula:C₆₇H₈₄N₁₆O₁₃
Color and Shape:Solid
Molecular weight:1321.48
Ref: TM-T76350
+ Info
Cinnamtannin A2
CAS:
- 86631-38-1
Cinnamtannin A2, a tetrameric procyanidin, boosts GLP-1, insulin, CRH expression, and has antioxidant, anti-diabetic, nephroprotective properties.
Formula:C₆₀H₅₀O₂₄
Color and Shape:Solid
Molecular weight:1155.02
Ref: TM-T40977
+ Info
15(S)-15-methyl Prostaglandin E2
CAS:
- 35700-27-7
15(S)-15-methyl PGE2: A stable PGE2 analog; strong antiulcer with double PGE2 affinity; excels PGE1 in uterine contraction.
Formula:C₂₁H₃₄O₅
Color and Shape:Solid
Molecular weight:366.49
Ref: TM-T36154
+ Info
(S)-V-0219 hydrochloride
(S)-V-0219 hydrochloride, a GLP-1R PAM, triggers calcium in hGLP-1R HEK cells, lowers glucose in mice, and reduces fasting hunger.
Formula:C₂₀H₂₆ClF₃N₄O₂
Color and Shape:Solid
Molecular weight:446.89
Ref: TM-T74265
+ Info
Cyclosomatostatin TFA
Cyclosomatostatin TFA blocks SST receptor, reduces CRC cell growth, ALDH+ size, and sphere-formation.
Formula:C₄₆H₅₈F₃N₇O₈
Color and Shape:Solid
Molecular weight:893.99
Ref: TM-T75842
+ Info
Labradimil
CAS:
- 159768-75-9
Labradimil, a bradykinin B2 agonist, boosts brain drug delivery and tumor survival rates.
Formula:C₄₉H₇₅N₁₅O₁₂S
Purity:98%
Color and Shape:Solid
Molecular weight:1098.29
Ref: TM-T27790
+ Info
GS-2278
CAS:
- 2750508-72-4
GS-2278 is an antagonist of LPAR1 (lysophosphatidic acid receptor 1) with potential applications in the study of idiopathic pulmonary fibrosis (IPF).
Formula:C₂₂H₁₆F₅N₉O₃
Color and Shape:Solid
Molecular weight:549.41
Ref: TM-T203480
+ Info
Bremelanotide
CAS:
- 189691-06-3
Bremelanotide is a synthetic peptide analog of alpha-MSH and is an agonist at melanocortin receptors including the MC3R and MC4R.
Formula:C₅₀H₆₈N₁₄O₁₀
Purity:98%
Color and Shape:White Powder
Molecular weight:1025.16
Ref: TM-T20467
+ Info
Endothelin 1 (swine, human), Alexa Fluor 488-labeled
Synthetic human/swine Endothelin 1 peptide, tagged with Alexa Fluor 488, acts as a strong vasoconstrictor via ET A/B receptors.
Color and Shape:Solid
Molecular weight:2848.4
Ref: TM-T76081
+ Info
Cannabigerorcinic Acid
CAS:
- 69734-83-4
Cannabigerorcinic acid, structurally akin to recognized phytocannabinoids, serves as an analytical reference standard designed for research and forensic purposes.
Formula:C₁₈H₂₄O₄
Color and Shape:Solid
Molecular weight:304.386
Ref: TM-TN7556
+ Info
5-OMe-UDP trisodium salt
CAS:
- 1207530-98-0
Potent P2Y6 agonist
Formula:C₁₀H₁₆N₂O₁₃P₂
Purity:98%
Color and Shape:Solid
Molecular weight:434.19
Ref: TM-T22525
+ Info
Synephrine hemitartrate
CAS:
- 16589-24-5
Synephrine hemitartrate, an alkaloid from Citrus aurantium, is a sympathomimetic for weight loss, with α and β-adrenergic action.
Formula:C₉H₁₃NO₂C₄H₆O₆
Color and Shape:Solid
Molecular weight:242.26
Ref: TM-T75425
+ Info
Kisspeptin-10, human TFA
"Kisspeptin-10, human TFA: vasoconstrictor, angiogenesis inhibitor, metastasis suppressor via GPR54, key in kidney development & osteoblast differentiation."
Formula:C₆₃H₈₃N₁₇O₁₄·C₂HF₃O₂
Color and Shape:Solid
Molecular weight:1416.46
Ref: TM-T75745
+ Info
Prepro-ANF (56-92), human
CAS:
- 112199-06-1
Human prepro-ANF (56-92) activates renal guanylate cyclase and boosts its activity.
Formula:C₁₇₃H₂₇₀N₄₄O₅₇
Color and Shape:Solid
Molecular weight:3878.26
Ref: TM-T76389