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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5378 products of "GPCR/G-Protein"

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  • ML-178
    Targetmol
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    ML-178

    CAS:
    <p>ML-178: selective S1PR4 agonist, EC50 of 46 nM; inactive on other S1P receptors at 25 μM.</p>
    Formula:C13H9Br2Cl2NO2
    Purity:95.92%
    Color and Shape:Solid
    Molecular weight:441.93

    Ref: TM-T22102

  • ML417
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    ML417

    CAS:
    <p>ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).</p>
    Formula:C22H25N3O3
    Purity:98.4% - 99.42%
    Color and Shape:Solid
    Molecular weight:379.45

    Ref: TM-T8423

  • Rizatriptan benzoate
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    Rizatriptan benzoate

    CAS:
    <p>Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine</p>
    Formula:C22H25N5O2
    Purity:99% - 99.79%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:391.47

    Ref: TM-T1512

  • SB 204741
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    SB 204741

    CAS:
    SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.
    Formula:C14H14N4OS
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:286.35

    Ref: TM-T23312

  • Istradefylline
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    Istradefylline

    CAS:
    <p>Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails.</p>
    Formula:C20H24N4O4
    Purity:98.18% - 99.95%
    Color and Shape:Solid
    Molecular weight:384.43

    Ref: TM-T6552

  • H4 Receptor antagonist 1
    Targetmol
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    H4 Receptor antagonist 1

    CAS:
    H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.
    Formula:C16H17ClN4O
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:316.79

    Ref: TM-T5829

  • 1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID
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    1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID

    CAS:
    <p>1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.</p>
    Formula:C13H13NO5
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:263.25

    Ref: TM-T8913

  • AZD4635
    Targetmol
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    AZD4635

    CAS:
    AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
    Formula:C15H11ClFN5
    Purity:99.15% - 99.90%
    Color and Shape:Solid
    Molecular weight:315.73

    Ref: TM-T4265

  • RVD-Hpα acetate(1193362-76-3 free base)
    Targetmol
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    RVD-Hpα acetate(1193362-76-3 free base)

    <p>RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.</p>
    Formula:C67H109N19O19
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:1484.71

    Ref: TM-TP1939L1

  • BIM-23190 aceate
    Targetmol
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    BIM-23190 aceate

    <p>BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies.</p>
    Formula:C59H83N13O14S2
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:1262.5

    Ref: TM-T39262L

  • LP-211
    Targetmol
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    LP-211

    CAS:
    LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.
    Formula:C30H34N4O
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:466.62

    Ref: TM-T5387

  • Montelukast
    Targetmol
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    Montelukast

    CAS:
    <p>Montelukast (Singular), oral asthma med, linked to rare liver injury.</p>
    Formula:C35H36ClNO3S
    Purity:98.56% - >99.99%
    Color and Shape:Solid
    Molecular weight:586.18

    Ref: TM-T1677

  • Ramosetron hydrochloride
    Targetmol
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    Ramosetron hydrochloride

    CAS:
    <p>Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant irritable bowel syndrome and nausea.</p>
    Formula:C17H18ClN3O
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:315.8

    Ref: TM-T4562L

  • Harmine
    Targetmol
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    Harmine

    CAS:
    <p>Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.</p>
    Formula:C13H12N2O
    Purity:98.29% - 99.92%
    Color and Shape:Off-White Solid
    Molecular weight:212.25

    Ref: TM-T1711

  • Capromorelin Tartrate
    Targetmol
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    Capromorelin Tartrate

    CAS:
    <p>Capromorelin Tartrate (CP 424391-18) is a potent, orally active growth hormone secretagogue receptor (GHSR) agonist (Ki: 7 nM for hGHS-R1a).</p>
    Formula:C32H41N5O10
    Purity:97.69%
    Color and Shape:Solid
    Molecular weight:655.7

    Ref: TM-TQ0022

  • Pramipexole dihydrochloride hydrate
    Targetmol
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    Pramipexole dihydrochloride hydrate

    CAS:
    <p>Pramipexole dihydrochloride hydrate (Mirapex) is a selective, blood-brain barrier-crossing D2 dopamine receptor agonist, and is used in the study of PD.</p>
    Formula:C10H17N3S·2HCl·H2O
    Purity:99.68%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:302.26

    Ref: TM-T6951

  • Sultopride hydrochloride
    Targetmol
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    Sultopride hydrochloride

    CAS:
    <p>Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective dopamine D2 and D3 receptor antagonist.</p>
    Formula:C17H27ClN2O4S
    Purity:≥95%
    Color and Shape:White Or Yellowish Powder
    Molecular weight:390.93

    Ref: TM-T7180

  • SHU 9119 acetate
    Targetmol
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    SHU 9119 acetate

    <p>SHU 9119 acetate: hMC3R &amp; hMC4R antagonist, hMC5R partial agonist. IC50: MC3R 0.23nM, MC4R 0.06nM, MC5R 0.09nM.</p>
    Formula:C56H75N15O11
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:1134.29

    Ref: TM-T16879L

  • Metoclopramide
    Targetmol
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    Metoclopramide

    CAS:
    <p>Metoclopramide: dopamine D2 antagonist, treats nausea, vomiting, gastroparesis, GERD; safe for pregnancy.</p>
    Formula:C14H22ClN3O2
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:299.80

    Ref: TM-T4616

  • Naftopidil dihydrochloride
    Targetmol
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    Naftopidil dihydrochloride

    CAS:
    <p>Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.</p>
    Formula:C24H28N2O3·2HCl
    Purity:99.76%
    Color and Shape:White Solid
    Molecular weight:465.41

    Ref: TM-T6600