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GPCR/G-Protein

GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5838 products of "GPCR/G-Protein"

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  • 5-HT2 agonist-1 free base

    CAS:
    Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,
    Formula:C19H22N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:310.39
  • YM543 free base

    CAS:
    "YM543 is an effective, oral SGLT2 inhibitor that lowers blood glucose, useful for diabetes research."
    Formula:C23H24O6
    Color and Shape:Solid
    Molecular weight:396.43
  • GSK-1004723

    CAS:
    GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.
    Formula:C39H49ClN4O2
    Color and Shape:Solid
    Molecular weight:641.28
  • S1P1 agonist 6 hemicalcium

    CAS:
    <p>Compound I (S1P1 agonist 6 hemicalcium) is an S1P1 agonist that diminishes autoimmune activity by inhibiting lymphocyte trafficking, and serves as an</p>
    Formula:C25H26F3NO3Ca
    Purity:98%
    Color and Shape:Solid
    Molecular weight:465.51
  • RBC10

    CAS:
    RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-
    Formula:C24H25ClN2O2
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:408.92
  • NKP608

    CAS:
    NKP608 is a NK-1 receptor antagonist with anticancer and anxiolytic activities.
    Formula:C31H24ClF6N3O2
    Purity:99.88% - 99.88%
    Color and Shape:Solid
    Molecular weight:619.99
  • LTB4 antagonist 2

    CAS:
    LTB4 antagonist 2, a carboxamide-acid compound, serves as an antagonist to leukotriene B4 (LTB4), possessing potential anti-inflammatory properties.
    Formula:C26H23NO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:445.46
  • Bivamelagon

    CAS:
    MC-4R Agonist 2 (Example 1), a melanocortin 4 receptor (MC4R) agonist, is employed in the research of conditions such as obesity, diabetes, inflammation, and
    Formula:C35H53ClN4O4
    Purity:100%
    Color and Shape:Solid
    Molecular weight:629.27
  • Dothiepin

    CAS:
    Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing
    Formula:C19H21NS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:295.44
  • Todralazine hydrochloride

    CAS:
    Todralazine hydrochloride, a β2AR blocker with antioxidant properties, is used in hypertension studies.
    Formula:C11H13ClN4O2
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:268.7
  • 1-Carboxycyclohexaneacetic Acid

    CAS:
    1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A.
    Formula:C9H14O4
    Color and Shape:Solid
    Molecular weight:186.207
  • FR-181877

    CAS:
    FR-181877: nonprostanoid PGI2 agonist, ADP-induced platelet aggregation inhibitor (IC50=0.081μM), orally bioavailable (56%), long half-life (4.3h) in rats.
    Formula:C30H28N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:480.55
  • GW-597901

    CAS:
    GW-597901, an β2 adrenergic receptor agonist, is used potentially for the treatment of asthma and chronic obstructive.
    Formula:C25H38N2O6S
    Color and Shape:Solid
    Molecular weight:494.64
  • AH13205

    CAS:
    AH13205 is an agonist of EP2 prostanoid receptor.
    Formula:C24H36O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:388.54
  • RS100329 hydrochloride

    CAS:
    RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.
    Formula:C20H26ClF3N4O3
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:462.89
  • Pecavaptan

    CAS:
    Pecavaptan is a vasopressin receptor antagonist.
    Formula:C22H19Cl2F3N6O3
    Color and Shape:Solid
    Molecular weight:543.33
  • GLP-1R agonist 10

    CAS:
    GLP-1R agonist 10 is a GLP-1 agonist (EC50: 0.051 nM).
    Formula:C29H29ClFN5O4
    Color and Shape:Solid
    Molecular weight:566.02
  • TA-1887

    CAS:
    TA-1887: Selective SGLT2 inhibitor, treats type 2 diabetes, lowers glucose in high-fat diet mice, boosts UGE, has good pharmacokinetics.
    Formula:C24H26FNO5
    Color and Shape:Solid
    Molecular weight:427.47
  • SAG 21k

    CAS:
    <p>SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.</p>
    Formula:C29H28ClF2N3O2S
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:556.07
  • Ertugliflozin L-pyroglutamic acid

    CAS:
    Ertugliflozin is a potent oral hSGLT2 inhibitor (IC50: 0.877 nM) for type 2 diabetes treatment studies.
    Formula:C27H32ClNO10
    Purity:99.88% - 99.94%
    Color and Shape:Solid
    Molecular weight:566