
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,003 products)
- Adenosine Receptor(247 products)
- Adrenergic Receptor(3,010 products)
- Bombesin Receptor(33 products)
- Bradykinin Receptor(60 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(215 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(435 products)
- Endothelin Receptor(83 products)
- GNRH Receptor(82 products)
- GPCR19(33 products)
- GRK(32 products)
- GTPase(22 products)
- Glucagon Receptor(190 products)
- Hedgehog/Smoothened(48 products)
- Histamine Receptor(381 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(321 products)
- PAFR(13 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5838 products of "GPCR/G-Protein"
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5-HT2 agonist-1 free base
CAS:Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Formula:C19H22N2O2Purity:98%Color and Shape:SolidMolecular weight:310.39YM543 free base
CAS:"YM543 is an effective, oral SGLT2 inhibitor that lowers blood glucose, useful for diabetes research."Formula:C23H24O6Color and Shape:SolidMolecular weight:396.43GSK-1004723
CAS:GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.Formula:C39H49ClN4O2Color and Shape:SolidMolecular weight:641.28S1P1 agonist 6 hemicalcium
CAS:<p>Compound I (S1P1 agonist 6 hemicalcium) is an S1P1 agonist that diminishes autoimmune activity by inhibiting lymphocyte trafficking, and serves as an</p>Formula:C25H26F3NO3CaPurity:98%Color and Shape:SolidMolecular weight:465.51RBC10
CAS:RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-Formula:C24H25ClN2O2Purity:99.71%Color and Shape:SolidMolecular weight:408.92NKP608
CAS:NKP608 is a NK-1 receptor antagonist with anticancer and anxiolytic activities.Formula:C31H24ClF6N3O2Purity:99.88% - 99.88%Color and Shape:SolidMolecular weight:619.99LTB4 antagonist 2
CAS:LTB4 antagonist 2, a carboxamide-acid compound, serves as an antagonist to leukotriene B4 (LTB4), possessing potential anti-inflammatory properties.Formula:C26H23NO6Purity:98%Color and Shape:SolidMolecular weight:445.46Bivamelagon
CAS:MC-4R Agonist 2 (Example 1), a melanocortin 4 receptor (MC4R) agonist, is employed in the research of conditions such as obesity, diabetes, inflammation, andFormula:C35H53ClN4O4Purity:100%Color and Shape:SolidMolecular weight:629.27Dothiepin
CAS:Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancingFormula:C19H21NSPurity:98%Color and Shape:SolidMolecular weight:295.44Todralazine hydrochloride
CAS:Todralazine hydrochloride, a β2AR blocker with antioxidant properties, is used in hypertension studies.Formula:C11H13ClN4O2Purity:99.91%Color and Shape:SolidMolecular weight:268.71-Carboxycyclohexaneacetic Acid
CAS:1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A.Formula:C9H14O4Color and Shape:SolidMolecular weight:186.207FR-181877
CAS:FR-181877: nonprostanoid PGI2 agonist, ADP-induced platelet aggregation inhibitor (IC50=0.081μM), orally bioavailable (56%), long half-life (4.3h) in rats.Formula:C30H28N2O4Purity:98%Color and Shape:SolidMolecular weight:480.55GW-597901
CAS:GW-597901, an β2 adrenergic receptor agonist, is used potentially for the treatment of asthma and chronic obstructive.Formula:C25H38N2O6SColor and Shape:SolidMolecular weight:494.64AH13205
CAS:AH13205 is an agonist of EP2 prostanoid receptor.Formula:C24H36O4Purity:98%Color and Shape:SolidMolecular weight:388.54RS100329 hydrochloride
CAS:RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.Formula:C20H26ClF3N4O3Purity:99.95%Color and Shape:SolidMolecular weight:462.89Pecavaptan
CAS:Pecavaptan is a vasopressin receptor antagonist.Formula:C22H19Cl2F3N6O3Color and Shape:SolidMolecular weight:543.33GLP-1R agonist 10
CAS:GLP-1R agonist 10 is a GLP-1 agonist (EC50: 0.051 nM).Formula:C29H29ClFN5O4Color and Shape:SolidMolecular weight:566.02TA-1887
CAS:TA-1887: Selective SGLT2 inhibitor, treats type 2 diabetes, lowers glucose in high-fat diet mice, boosts UGE, has good pharmacokinetics.Formula:C24H26FNO5Color and Shape:SolidMolecular weight:427.47SAG 21k
CAS:<p>SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.</p>Formula:C29H28ClF2N3O2SPurity:99.51%Color and Shape:SolidMolecular weight:556.07Ertugliflozin L-pyroglutamic acid
CAS:Ertugliflozin is a potent oral hSGLT2 inhibitor (IC50: 0.877 nM) for type 2 diabetes treatment studies.Formula:C27H32ClNO10Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:566
