GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,024 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,029 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(159 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(443 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(83 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(42 products)
- Opioid Receptor(326 products)
- PAFR(14 products)
- PKA(52 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5972 products of "GPCR/G-Protein"
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Diosuxentan
CAS:Diosuxentan is an inhibitor of ETA and is utilized in research pertaining to cardiovascular, renal, and neuronal inflammatory diseases.Formula:C20H21BrN6O7SColor and Shape:SolidMolecular weight:569.39MK-8318
CAS:MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).Formula:C27H26F4N2O5Purity:98%Color and Shape:SolidMolecular weight:534.5Rivenprost
CAS:Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.Formula:C24H34O6SColor and Shape:SolidMolecular weight:450.59CS-003 Free base
CAS:CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.Formula:C34H38Cl2N2O6SPurity:98%Color and Shape:SolidMolecular weight:673.65Dopamine D4 receptor ligand 3
CAS:Dopamine D4 receptor ligand 3 (Compound 16) functions as a dopamine D4 receptor (D4R) antagonist with a pKi of 8.86. In HEK-293T cells, it shows pIC50 values of 5.78, 5.55, and 6.17 for Go, Gi, and βArr2 sensors, respectively. This compound inhibits the activity of human glioma cell lines U87 MG, T98G, and U251 MG, and it induces ROS production and mitochondrial dysfunction in these glioma cells.Formula:C28H31N3O5Color and Shape:SolidMolecular weight:489.56SAR-150640
CAS:SAR-150640, a selective β3-adrenergic receptor agonist, prevents an increase in MMP activity and production observed after LPS stimulation or in cases of chorioamnionitis.Formula:C25H35ClN2O7SColor and Shape:SolidMolecular weight:543.07CB2 receptor antagonist 1
CAS:Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.Formula:C28H47NO3Color and Shape:SolidMolecular weight:445.68Neflumozide
CAS:Neflumozide (HRP 913) is an orally effective derivative of benzisoxazole, characterized by its potent dopamine antagonist properties and antipsychotic activity. It is utilized in research related to psychiatric disorders.Formula:C22H23FN4O2Color and Shape:SolidMolecular weight:394.44Sigma-2 Radioligand 2
CAS:Sigma-2 Radioligand 2 (compound 4) exhibits low nanomolar affinity for the σ2 receptor (Ki=2.30 nM) and high subtype selectivity (Ki(σ1)/Ki(σ2) > 1500).Formula:C23H28FN3O3Color and Shape:SolidMolecular weight:413.49Bzo-poxizid
CAS:Bzo-poxizid is a synthetic cannabinoid and a psychoactive substance.Formula:C20H21N3O2Color and Shape:SolidMolecular weight:335.40Jimscaline
CAS:Jimscaline (compound R-(-)2) is a 5-HT2A agonist and a mescaline analogue, used in neuroscience research.Formula:C13H19NO3Molecular weight:237.295CB1/2 receptor-1
CAS:CB1/2 receptor-1 (compound 5.3) serves as an agonist for CB1/2 receptors and is utilized in angiogenesis research.Formula:C33H48O2Color and Shape:SolidMolecular weight:476.73LPA2 antagonist 6
CAS:LPA2 antagonist 6 (example 2) acts as an antagonist of Lp(a). It inhibits the formation of Lp(a) with an IC50 value of 2.33 nM, making it useful for cardiovascular disease research.Formula:C26H34Cl2N2O6Color and Shape:SolidMolecular weight:541.464Gemilukast
CAS:Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.Formula:C36H37F2NO5Purity:98.27% - 99.5%Color and Shape:SolidMolecular weight:601.68Ref: TM-T11388
1mg115.00€5mg274.00€10mg472.00€25mg914.00€50mg1,415.00€100mg2,517.00€1mL*10mM (DMSO)363.00€MRGPRX2 modulator-1
CAS:MRGPRX2 modulator-1 (example 17), a modulator of the mas-related G-protein receptor X2 (MRGPRX2), is employed in studies focused on inflammation, pain, and autoimmune disorders [1].Formula:C20H19F6N5OColor and Shape:SolidMolecular weight:459.39Burapitant
CAS:<p>Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.</p>Formula:C31H35Cl2F6N3O3Purity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:682.52AL 6598
CAS:AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.Formula:C23H39ClO5Color and Shape:SolidMolecular weight:431.01Dopamine D3 receptor antagonist-2
Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.Formula:C23H27Cl2N3O3Color and Shape:SolidMolecular weight:464.38Taprostene
CAS:Taprostene (CG-4203), a stable Prostacyclin analogue, protects endothelium and myocardium post-ischemia in cats, with minimal hemodynamic impact.Formula:C24H30O5Color and Shape:SolidMolecular weight:398.49Abarelix acetate
CAS:Abarelix acetate: synthetic GnRHR antagonist, spikes histamine, lowers LH and testosterone temporarily, used in advanced prostate cancer.Formula:C72H95ClN14O14·xC2H4O2Color and Shape:SolidMolecular weight:1476.14LPA5 antagonist 2
LPA5 antagonist 2, compound 65, water-soluble, reduces nociception, for inflammatory/neuropathic pain study.Formula:C26H25FN2O4SColor and Shape:SolidMolecular weight:480.55Disulergine
CAS:Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.Formula:C17H24N4O2SPurity:98%Color and Shape:SolidMolecular weight:348.46ATL444
CAS:ATL444 is an adenosine receptor antagonist with affinity (Ki values) for rA1AR, rA2AAR, rA2BAR, and rA3AR of 7.0, 2.5, 61.8, and >1000 nM, respectively.Formula:C17H19N5OColor and Shape:SolidMolecular weight:309.37Ophiobolin C
CAS:inhibitor of human CCR5 binding to HIV-1 gp120Formula:C25H38O3Purity:98%Color and Shape:SolidMolecular weight:386.57CB2R/5-HT1AR agonist 1
CAS:Compound 2o, also known as CB2R/5-HT1AR agonist 1, serves as a partial orally active agonist for the CB2 receptor (EC50 = 479.6 nM) and a full agonist for the 5-HT1A receptor (EC50 = 2.7 μM). This compound demonstrates both anti-anxiety and anti-depressive effects and has favorable pharmacokinetic properties [1].Formula:C24H33NO3Color and Shape:SolidMolecular weight:383.52Aeruginosin 98-B
CAS:Aeruginosin 98-B, a protease inhibitor, effectively inhibits trypsin, plasmin, and thrombin with IC50 values of 0.6, 7.0, and 10.0 μg/mL, respectively.Formula:C29H46N6O9SColor and Shape:SolidMolecular weight:654.78TAK-024
CAS:TAK-024 is an inhibitor of platelet(IC50s of 31, 79 and 51 nM in human, monkey and guinea pig, respectively).Formula:C27H34N10O6Purity:98%Color and Shape:SolidMolecular weight:594.62Protease-Activated Receptor-1 antagonist 1
Compound 13 is a PAR-1 antagonist with a 3 nM IC50, useful for thrombosis and heart disease research.Formula:C25H24F2N2O3Color and Shape:SolidMolecular weight:438.47LAS195319
CAS:LAS195319 is a potent and selective inhaled PI3Kδ Inhibitor (IC50 = 0.5 nM) for the Treatment of Respiratory Diseases.Formula:C29H26N10O3SColor and Shape:SolidMolecular weight:594.65Atumelnant
CAS:Atumelnant (CRN04894) is an MC2R antagonist used in the study of congenital adrenocortical hyperplasia (CAH) and Cushing's disease (CD).Formula:C33H42F3N5O3Purity:98.41%Color and Shape:SolidMolecular weight:613.71GRPR antagonist-1
GRPR antagonist-1 targets GRPR, kills specific cancer cells (e.g., PC3, Pan02, HGC-27), and promotes apoptosis by modulating Bcl-2 and Bax.Formula:C29H33F3N4O4Color and Shape:SolidMolecular weight:558.59MSX-3
CAS:MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.Formula:C21H23N4Na2O7PPurity:98%Color and Shape:SolidMolecular weight:520.389LY 292728
CAS:LY 292728 is a highly potent antagonist of leukotriene B4 receptor.Formula:C34H29FO9Purity:98%Color and Shape:SolidMolecular weight:600.59TAK-075
CAS:TAK-075 is an orally active CaSR antagonist with an IC50 value of 0.94 nM. It transiently stimulates parathyroid hormone (PTH) secretion in rats and effectively prevents significant reduction in PTH secretion due to the accumulation of active metabolites, thereby maintaining a normal secretion pattern. TAK-075 is applicable in research related to metabolic diseases and osteoporosis.Formula:C36H46N4O4SColor and Shape:SolidMolecular weight:630.84AM9405
AM9405: peripheral CB1/5-HT3 agonist, suppresses gut motility, relieves GI disorder symptoms in mice.Formula:C24H33BrN2O2Purity:98%Color and Shape:SolidMolecular weight:461.44Rodatristat ethyl
CAS:Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.Formula:C29H31ClF3N5O3Purity:98%Color and Shape:SolidMolecular weight:590.04LY 245769
CAS:LY 245769 is an inhibitor of leukotriene E4 (LTE4).Formula:C25H33F3N8OSPurity:98%Color and Shape:SolidMolecular weight:550.64SST1 receptor antagonist-1
CAS:SST1 receptor antagonist-1 (Compound 23) is a selective antagonist of the somatostatin receptor 1 (SST1), showing a pKd of 9.11 for rSST1 and 8.79 for hSST1. This compound is applicable in research related to retinal and endocrine dysfunction, cancer, and neuropsychiatric disorders.Formula:C29H31F2N3O2Color and Shape:SolidMolecular weight:491.57MDMB-FUBICA
CAS:MDMB-FUBICA is a potent agonist of the cannabinoid receptors and exhibits psychoactive properties. It can be utilized in e-cigarettes.Formula:C23H25FN2O3Color and Shape:SolidMolecular weight:396.455BI-113823
CAS:BI-113823 is an orally active and selective bradykinin B1 receptor antagonist. It alleviates mechanical hyperalgesia induced by complete Freund's adjuvant in rats. BI-113823 is applicable for research on chronic inflammatory pain.Formula:C26H44N4O5SColor and Shape:SolidMolecular weight:524.716YNT-3708
CAS:YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.Formula:C35H36N4O6SColor and Shape:SolidMolecular weight:640.74925B-NBOH hydrochloride
CAS:25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.Formula:C17H21BrClNO3Color and Shape:SolidMolecular weight:402.711UK-432097
CAS:UK 432097 is an adenosine A2A agonist.Formula:C40H47N11O6Color and Shape:SolidMolecular weight:777.87CCR3 antagonist 2
CAS:CCR3 antagonist2 (example 66) is a CCR3 antagonist useful for researching inflammatory or allergic diseases, particularly those affecting the respiratory tract, such as inflammatory or obstructive airway conditions.Formula:C21H28ClN5O3Color and Shape:SolidMolecular weight:433.93Rocavorexant
CAS:Rocavorexant is an antagonist of the orexin-1 receptor (orexin-1 receptor), exhibiting a pIC50 value of 9.1 for human OX1 and a pIC50 of 6.0 for human OX2.Formula:C18H19F3N8OColor and Shape:SolidMolecular weight:420.392RS 12254
CAS:RS 12254 is a dopamine agonist and antihypertensive agent.Formula:C28H40N2O4Purity:98%Color and Shape:SolidMolecular weight:468.63PF-06372222
CAS:<p>PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.</p>Formula:C26H28F3N5O3Purity:98%Color and Shape:SolidMolecular weight:515.53SB 243213 dihydrochloride
CAS:SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 forFormula:C22H21Cl2F3N4O2Purity:98%Color and Shape:SolidMolecular weight:501.33BMS-986120
CAS:BMS-986120: Oral, reversible PAR4 antagonist. IC50: 9.5 nM (human), 2.1 nM (monkey). Potent, selective antiplatelet.Formula:C23H23N5O5S2Color and Shape:SolidMolecular weight:513.59LY3154207
CAS:LY3154207: selective, potent oral human dopamine D1 receptor PAM, low agonist activity, EC50=3 nM.Formula:C24H29Cl2NO3Color and Shape:SolidMolecular weight:450.4LK 11
CAS:LK-11, an alkaloid derivative, inhibits the passive uptake of norepinephrine (NA) by synaptic vesicles in the thalamus, similarly to cocaine.Formula:C15H26N2O3Color and Shape:SolidMolecular weight:282.38Mrgx2 antagonist-3
CAS:<p>Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.</p>Formula:C15H15F2N3OColor and Shape:SolidMolecular weight:291.30Ici D1542
CAS:Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.Formula:C25H30N2O7Purity:98%Color and Shape:SolidMolecular weight:470.51U75302
CAS:U75302 is an antagonist of thymosin beta-4 (TB4) receptor with a Ki value of 159 nM on guinea pig lung membranes.Formula:C22H35NO3Purity:98%Color and Shape:Light Yellow OilMolecular weight:361.52Rimegepant sulfate hydrate
CAS:Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.Formula:C56H64F4N12O13SColor and Shape:SolidMolecular weight:1221.2526NK-1 Antagonist 1
CAS:NK-1 Antagonist 1 is a NK-1 receptor antagonist.Formula:C25H23F6N5O2Purity:98%Color and Shape:SolidMolecular weight:539.47AH22921
CAS:AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.Formula:C29H35NO5Color and Shape:SolidMolecular weight:477.59SEP-363856 mesylate
CAS:SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.Formula:C10H17NO4S2Color and Shape:SolidMolecular weight:279.38TM38837
CAS:<p>CB1 antagonist 4 is an inverse agonist of cannabinoid receptor 1 (CB1) with an IC50 of 0.4 nM. It can reduce body weight, improve plasma inflammatory markers, and enhance glucose homeostasis [1].</p>Formula:C27H20Cl2F3N7OColor and Shape:SolidMolecular weight:586.40Cannabigerovarin
CAS:Cannabigerovarin (CBGV) is a compound categorized as a phytocannabinoid.Formula:C19H28O2Molecular weight:288.42A3AR antagonist 5
CAS:A3AR antagonist 5 (Compound 16) acts as a selective antagonist for the human adenosine A3 receptor (human adenosine A3 receptor), with an affinity expressed as a pC value of 4.542 μM.Formula:C18H16N2O2SColor and Shape:SolidMolecular weight:324.405-HT6R/MAO-B modulator 1
5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.Formula:C33H38N4O3SColor and Shape:SolidMolecular weight:570.74DSP-1053 benzenesulfonate
CAS:DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.Formula:C32H38BrNO7SColor and Shape:SolidMolecular weight:660.62(S)-Butaprost free acid
CAS:(S)-Butaprost (free acid) is a potent and highly selective EP2 receptor agonist[1].Formula:C23H38O5Color and Shape:SolidMolecular weight:394.54PF-00446687
CAS:PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).Formula:C28H36F2N2O2Purity:98%Color and Shape:SolidMolecular weight:470.59Anti-MRSA agent 19
CAS:Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against Staphylococcus aureus. It is active against 40 clinical isolates from the CDC, representing diverse bacterial species with various resistance factors, including resistance to vancomycin, aminoglycoside/tetracycline, and oxazolidinone (median MIC=4 μg/mL).Formula:C15H10Cl3NO4Color and Shape:SolidMolecular weight:374.6Lp(a)-IN-8
CAS:LPA2 antagonist 3 (compound 15) serves as an Lp(a) antagonist. Lp(a) is a pathogenic risk factor for atherosclerotic cardiovascular disease (ASCVD).Formula:C21H40Cl2N4O5Color and Shape:SolidMolecular weight:499.472BI 703704
CAS:BI 703704, a soluble guanylate cyclase (sGC) activator, inhibits the progression of diabetic nephropathy in the ZSF1 rat [1].Formula:C32H37N3O4SPurity:98%Color and Shape:SolidMolecular weight:559.72R-137696
CAS:R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.Formula:C17H23N3O2Color and Shape:SolidMolecular weight:301.388 Hydroxy PIPAT oxalate
CAS:8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.Formula:C18H24INO5Color and Shape:SolidMolecular weight:461.295-HT2A/5-HT2C inverse agonist 1
CAS:5-HT2A/5-HT2C inverse agonist 1 serves as a dual and potent inverse agonist for the 5-HT2A and 5-HT2C receptors, with hERG inhibition properties that mitigate cardiovascular risks. Demonstrating significant antipsychotic efficacy in the MK-801-induced mouse model, this compound holds potential for psychosis research.Formula:C24H35N5O2Color and Shape:SolidMolecular weight:425.57AAZ-A 154 hydrobromide
CAS:AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Formula:C14H21BrN2OColor and Shape:SolidMolecular weight:313.23SB 224289
CAS:SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Formula:C32H32N4O3Purity:98%Color and Shape:SolidMolecular weight:520.62L-97-1
CAS:L-97-1 is an antagonist of the adenosine A1 receptor.Formula:C29H38N6O3Purity:98%Color and Shape:SolidMolecular weight:518.65LAB687
CAS:LAB687 (Compound 2a) is an inhibitor of microsomal triglyceride transfer protein (MTP) with an IC50 of 0.9 nM for inhibiting the secretion of apolipoprotein B (apoB) in HepG2 cells. Additionally, LAB687 acts as a Smoothened (Smo) antagonist, exhibiting IC50 values of 2.48 μM and 3.42 μM for mouse and human Smo receptors, respectively. This compound is effective in reducing triglyceride and low-density lipoprotein cholesterol (LDL-C) levels and in inhibiting the Hedgehog signaling pathway.Formula:C26H23F3N2O3Color and Shape:SolidMolecular weight:468.47IMP-1575
CAS:IMP-1575 is a highly effective inhibitor of hedgehog acyltransferase (HHAT), with an IC50 of 0.75 μM when inhibiting purified HHAT. IMP-1575 has potential applications in cancer research.Formula:C19H25N3OSMolecular weight:343.49YM158 free base
CAS:YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).Formula:C32H33ClN6O5S2Purity:98%Color and Shape:SolidMolecular weight:681.22RXFP1 receptor agonist-10
CAS:RXFP1 receptor agonist-10 (Compound 188) is an RXFP1 receptor agonist with an EC50 of 0.5 nM. It is useful for research into heart failure.Formula:C39H44F6N4O5Color and Shape:SolidMolecular weight:762.78(Rac)-BI 703704
CAS:(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC).Formula:C32H37N3O4SPurity:98%Color and Shape:SolidMolecular weight:559.72MK-0812
CAS:MK-0812 is a dual antagonist of the CCR2 and CCR5 receptors that can alleviate adipose inflammation in ob/ob mice.Formula:C24H34F3N3O3Purity:98%Color and Shape:SolidMolecular weight:469.54GRK6-IN-5
CAS:GRK6-IN-5 is an inhibitor of the GRK6 polypeptide, with an IC50 of 4.48 μM. GRK6-IN-5 is utilized in research focused on hematological malignancies, inflammatory diseases, and autoimmune disorders.Formula:C23H21N3O2Color and Shape:SolidMolecular weight:371.432MRT-92
CAS:MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.Formula:C33H34N4O5Color and Shape:SolidMolecular weight:566.65APJ receptor agonist 3
CAS:APJ receptor agonist 3 is a highly effective and orally administerable agonist of the APJ receptor, demonstrating a potent EC50 value of 0.027 nM.Formula:C26H29ClN4O5Color and Shape:SolidMolecular weight:512.98Revexepride
CAS:Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.Formula:C21H32ClN3O4Purity:98%Color and Shape:SolidMolecular weight:425.95Flucopride
CAS:Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.Formula:C22H33FN2O2Color and Shape:SolidMolecular weight:376.51Mafoprazine
CAS:Mafoprazine, a phenylpiperazine derivative, exhibits varying affinities for neuronal receptors, primarily exerting its antipsychotic effects through blocking D2 receptors and enhancing α-adrenergic activity. It also increases the activity of dopamine metabolites.Formula:C22H28FN3O3Color and Shape:SolidMolecular weight:401.47Sulamserod hydrochloride
CAS:Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.Formula:C19H29Cl2N3O5SColor and Shape:SolidMolecular weight:482.42GRK6-IN-4
CAS:GRK6-IN-4 is an inhibitor of G protein-coupled receptor kinase 6 (GRK6) with an IC50 value of 1.56 μM. GRK6-IN-4 is applicable for research related to hematological malignancies, inflammatory diseases, and autoimmune disorders.Formula:C15H15N5Color and Shape:SolidMolecular weight:265.313CI-988
CAS:CCK2 (CCK-B) receptor antagonistFormula:C35H42N4O6Purity:98%Color and Shape:SolidMolecular weight:614.73Alixorexton
CAS:Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.Formula:C21H30N2O5SColor and Shape:SolidMolecular weight:422.538Etoperidone
CAS:Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).Formula:C19H28ClN5OColor and Shape:SolidMolecular weight:377.91SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFormula:C22H20ClF3N4O2Purity:98%Color and Shape:SolidMolecular weight:464.87GPBAR1-IN-3
CAS:GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].Formula:C21H23NO2Color and Shape:SolidMolecular weight:321.41(S)-Bucindolol
CAS:(S)-Bucindolol is an enantiomer of bucindolol, specifically a β1-adrenergic receptor antagonist. It is primarily utilized in research related to heart failure.Formula:C22H25N3O2Color and Shape:SolidMolecular weight:363.45TAK-661
CAS:TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.Formula:C13H21N5O3SColor and Shape:SolidMolecular weight:327.40LPA receptor antagonist-1
CAS:LPA receptor antagonist-1 (example 52) serves as an antagonist for the lysophosphatidic acid (LPA) receptor and is applicable in various types of studies [1].Formula:C30H26ClNO5SMolecular weight:548.05CVT-5440
CAS:CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.Formula:C27H28N6O5Color and Shape:SolidMolecular weight:516.55Avitriptan
CAS:Avitriptan is a 5-HT1B/1D receptor agonist with pKi values of 7.44 for 5-HT1Brat, 7.68 for 5-HT1Bhuman, and 8.36 for 5-HT1Dhuman. It can induce contraction in isolated coronary arteries and is used for the treatment of migraines.Formula:C22H30N6O3SMolecular weight:458.577VGD071
CAS:VGD071, a compound that targets sortilin, presents a promising avenue for forthcoming research utilizing mouse models of breast cancer.Formula:C32H41N3O4S2Color and Shape:SolidMolecular weight:595.82RTIOXA-43
CAS:RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.Formula:C37H37N5O5SPurity:99.17%Color and Shape:SolidMolecular weight:663.79Ref: TM-T87345
1mg221.00€5mg545.00€10mg879.00€25mg1,696.00€50mg2,725.00€100mg3,686.00€1mL*10mM (DMSO)795.00€Mesulergine hydrochloride
CAS:5-HT2A and 2C receptor antagonistFormula:C18H27ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:398.95S1P1 agonist 5
Selective oral S1P1 agonist 5 inhibits lymphocyte drainage, potential for MS research.Formula:C23H24ClN2NaO4Color and Shape:SolidMolecular weight:450.89Acyline
CAS:Acyline, a GnRH antagonist, suppresses gonadotropins and testosterone in animals and maintains the effect for 2 weeks in men with one dose.Formula:C80H102ClN15O14Color and Shape:SolidMolecular weight:1533.21Cloprostenol
CAS:Cloprostenol is a synthetic prostaglandin and PGF2α analogue used in animals to terminate pregnancy and induce corpus luteum dissolution.Formula:C22H29ClO6Purity:99.81%Color and Shape:Clear Colorless To Light Yellowish LiquidMolecular weight:424.92GPR27 agonist-1
CAS:GPR27 agonist-1 (compound I) is a selective agonist for GPR27 with a pEC50 value of 6.34.Formula:C19H14Cl2N2O3SColor and Shape:SolidMolecular weight:421.30BQ-788
CAS:BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formula:C34H51N5O7Purity:98.81%Color and Shape:SolidMolecular weight:641.8Ref: TM-T10595
1mg137.00€2mg188.00€5mg329.00€10mg472.00€25mg753.00€50mg1,017.00€100mg1,378.00€500mg2,737.00€1mL*10mM (DMSO)360.00€Treprostinil diethanolamine
CAS:<p>Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,</p>Formula:C27H45NO7Purity:99.86%Color and Shape:SolidMolecular weight:495.65LSN3318839
CAS:<p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>Formula:C26H23Cl2N3O2Purity:99.21%Color and Shape:SolidMolecular weight:480.39AZD-5672
CAS:AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.Formula:C32H38F2N2O5S2Purity:98.1%Color and Shape:SolidMolecular weight:632.78Ref: TM-T30260
1mg202.00€5mg459.00€10mg643.00€25mg938.00€50mg1,311.00€100mg1,786.00€1mL*10mM (DMSO)560.00€Dersimelagon
CAS:Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.Formula:C36H45F4N3O5Purity:97.35% - 98.23%Color and Shape:SolidMolecular weight:675.75SB-224289 hydrochloride
CAS:SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formula:C32H33ClN4O3Purity:98.99% - 99.96%Color and Shape:SolidMolecular weight:557.08AZD5462
CAS:AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.Formula:C30H41FN2O6Purity:98.32% - 99.63%Color and Shape:SolidMolecular weight:544.65SB-423562
CAS:SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.Formula:C26H32N2O4Purity:99.22%Color and Shape:SolidMolecular weight:436.54Ref: TM-T12846
1mg39.00€5mg85.00€10mg126.00€25mg221.00€50mg338.00€100mg467.00€200mg640.00€1mL*10mM (DMSO)94.00€Vofopitant
CAS:Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).Formula:C21H23F3N6OPurity:97.86%Color and Shape:SolidMolecular weight:432.44PF-07258669
CAS:PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.Formula:C25H27FN6O2Purity:99.9%Color and Shape:SolidMolecular weight:462.52BMS-986141
CAS:BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Formula:C27H23N5O5S2Purity:98.43% - 99.26%Color and Shape:SolidMolecular weight:561.63Vofopitant dihydrochloride
CAS:Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.Formula:C21H25Cl2F3N6OPurity:98.99%Color and Shape:SolidMolecular weight:505.36Ref: TM-T13329L
1mg99.00€5mg235.00€10mg376.00€25mg712.00€50mg1,064.00€100mg1,454.00€500mg2,822.00€1mL*10mM (DMSO)261.00€Rolapitant hydrochloride
CAS:Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.Formula:C25H27ClF6N2O2Purity:98.35% - 99.79%Color and Shape:SolidMolecular weight:536.94Ref: TM-T3724
1mg153.00€5mg365.00€10mg520.00€25mg780.00€50mg1,054.00€100mg1,425.00€200mg1,882.00€1mL*10mM (DMSO)439.00€Protease-Activated Receptor-4
CAS:Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.Formula:C33H46N8O7Purity:98%Color and Shape:SolidMolecular weight:666.77Arotinolol
CAS:Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Formula:C15H21N3O2S3Color and Shape:White SolidMolecular weight:371.547-Desmethyl-agomelatine
CAS:7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.Formula:C14H15NO2Color and Shape:SolidMolecular weight:229.27CYM 9484
CAS:CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.Formula:C27H31N3O3S2Color and Shape:SolidMolecular weight:509.68BIBP3226 TFA
CAS:BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).Formula:C29H32F3N5O5Color and Shape:SolidMolecular weight:587.59SHA 68
CAS:SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.Formula:C26H24FN3O3Purity:98%Color and Shape:SolidMolecular weight:445.49ML-00253764 hydrochloride
CAS:ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).Formula:C18H19BrClFN2OColor and Shape:SolidMolecular weight:413.71SR 146131
CAS:SR 146131 is a potent and selective agonist of the nonpeptide receptor.Formula:C32H36ClN3O5SPurity:98%Color and Shape:SolidMolecular weight:610.16HOKU-81
CAS:HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.Formula:C12H18ClNO2Color and Shape:SolidMolecular weight:243.73JMV 2959
CAS:JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).Formula:C30H32N6O2Color and Shape:SolidMolecular weight:508.61Pumosetrag Hydrochloride
CAS:Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formula:C15H18ClN3O2SPurity:98%Color and Shape:SolidMolecular weight:339.84SB-399885 hydrochloride
CAS:SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Formula:C18H22Cl3N3O4SPurity:98%Color and Shape:SolidMolecular weight:482.81Beraprost sodium
CAS:Beraprost sodium is a stable and orally active prodrug of PGI2.Formula:C24H29NaO5Color and Shape:SolidMolecular weight:420.481ML-290
CAS:ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.Formula:C24H21F3N2O5SColor and Shape:SolidMolecular weight:506.49BRL 15572
CAS:BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.Formula:C25H27ClN2OColor and Shape:SolidMolecular weight:406.95GSK-3050002
<p>GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.</p>Color and Shape:Odour LiquidAmelubant
CAS:Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.Formula:C33H34N2O5Purity:98%Color and Shape:SolidMolecular weight:538.63SKF 89748
CAS:SKF 89748 is an agonists of alpha 1-adrenoceptor.Formula:C12H17NOSPurity:98%Color and Shape:SolidMolecular weight:223.333-Hydroxybenzylamine
CAS:3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.Formula:C7H9NOColor and Shape:SolidMolecular weight:123.155TAK-448
CAS:TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.Formula:C58H80N16O14Purity:98%Color and Shape:SolidMolecular weight:1225.36Sarizotan
CAS:Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.Formula:C22H21FN2OColor and Shape:SolidMolecular weight:348.421N-methyl-2-AI (hydrochloride)
CAS:N-methyl-2-AI (hydrochloride) is a useful organic compound for research related to life sciences. The catalog number is T66396 and the CAS number is 10408-85-2.Formula:C10H14ClNColor and Shape:SolidMolecular weight:183.68(Rac)-Zevaquenabant
CAS:(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.Formula:C25H21ClF3N5O2SColor and Shape:SolidMolecular weight:547.98(R)-(-)-α-Methylhistamine dihydrochloride
CAS:R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.Formula:C6H13Cl2N3Color and Shape:SolidMolecular weight:198.09Picumeterol
CAS:Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.Formula:C21H29Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:426.38TAK-683
CAS:TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.Formula:C64H83N17O13Purity:98%Color and Shape:SolidMolecular weight:1298.456-Chloro-5-(2-chloroethyl)indolin-2-one
CAS:6-Chloro-5-(2-chloroethyl)indolin-2-one is a useful organic compound for research related to life sciences. The catalog number is T64862 and the CAS number is 118289-55-7.Formula:C10H9Cl2NOColor and Shape:SolidMolecular weight:230.09CRTh2 antagonist 3
CAS:CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.Formula:C19H20N2O3SPurity:98%Color and Shape:SolidMolecular weight:356.441-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol
CAS:1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol is a useful organic compound for research related to life sciences. The catalog number is T65156 and the CAS number is 24155-42-8.Formula:C11H10Cl2N2OColor and Shape:SolidMolecular weight:257.11Anti-GLP1R Antibody
<p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>Color and Shape:Odour Liquid4-Hydroxyatomoxetine
CAS:4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.Formula:C17H21NO2Purity:98%Color and Shape:SolidMolecular weight:271.35dapitant
CAS:Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.Formula:C37H39NO4Color and Shape:SolidMolecular weight:561.71Vornorexant
CAS:Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.Formula:C23H22FN7O2Color and Shape:SolidMolecular weight:447.474Patecibart
CAS:<p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>Purity:98%Color and Shape:Liquid1-Oleoyl Lysophosphatidic Acid
CAS:<p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>Formula:C21H41O7PColor and Shape:SolidMolecular weight:436.52Ref: TM-T36907
Discontinued product4-Hydroxypropranolol hydrochloride
CAS:4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).Formula:C16H22ClNO3Purity:98%Color and Shape:SolidMolecular weight:311.8Desmethyl cariprazine
CAS:Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).Formula:C20H30Cl2N4OPurity:98%Color and Shape:SolidMolecular weight:413.38BX471 hydrochloride
CAS:BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.Formula:C21H25Cl2FN4O3Purity:98%Color and Shape:SolidMolecular weight:471.35Goserelin acetate(65807-02-5 Free base)
<p>Goserelin acetate （ICI-118630 acetate） is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.</p>Purity:99.77%Color and Shape:Odour SolidRef: TM-T36918L
Discontinued productPropiram fumarate HCl
CAS:<p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>Formula:C16H25N3O·xClHPurity:99.25%Color and Shape:SoildCanagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Formula:C24H25FO5SPurity:98%Color and Shape:SolidMolecular weight:448.542-Methyl-5-HT hydrochloride
CAS:2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formula:C11H15ClN2OPurity:98%Color and Shape:SolidMolecular weight:226.7RU 24969 succinate
CAS:<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Formula:C18H22N2O5Color and Shape:SolidMolecular weight:346.38Pamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Formula:C23H16O6Purity:99.99%Color and Shape:Fine Yellow PowderMolecular weight:388.37SB251023
CAS:SB251023 is an agonist of β3-adrenoceptor.Formula:C28H34NO6PColor and Shape:SolidMolecular weight:511.55Neurokinin antagonist 1
CAS:Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.Formula:C38H40N4O3Purity:>99.99%Color and Shape:SolidMolecular weight:600.75MEN11467
CAS:MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.Formula:C38H40N4O3Purity:>99.99%Color and Shape:SolidMolecular weight:600.75Imetit dihydrobromide
CAS:Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Formula:C6H12Br2N4SPurity:98%Color and Shape:SolidMolecular weight:332.06GR 218,231
CAS:GR 218,231 is a selective antagonist of D3 dopamine receptor.Formula:C24H33NO3SPurity:98%Color and Shape:SolidMolecular weight:415.59Flumexadol
CAS:Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Formula:C11H12F3NOPurity:98%Color and Shape:SolidMolecular weight:231.21S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Formula:C25H26F3NO3Purity:98%Color and Shape:SolidMolecular weight:445.47AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Formula:C29H40O3Purity:99.58%Color and Shape:SolidMolecular weight:436.63Dimethandrolone Undecanoate
CAS:Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.Formula:C31H50O3Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:470.73Ref: TM-T27176
Discontinued product2-MNG
CAS:<p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>Formula:C8H8N2O3SColor and Shape:LiquidMolecular weight:212.23
