
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,024 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,029 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(159 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(443 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(83 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(42 products)
- Opioid Receptor(326 products)
- PAFR(14 products)
- PKA(52 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5972 products of "GPCR/G-Protein"
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A-940894
CAS:A-940894: Potent H4 receptor antagonist, anti-inflammatory, binds well to human/rat H4, low affinity for H1/H2/H3, good pharmacokinetics.Formula:C17H21N5Color and Shape:SolidMolecular weight:295.38Niperotidine
CAS:Niperotidine is an antagonist of histamine H2-receptor.Formula:C20H26N4O5SPurity:98%Color and Shape:SolidMolecular weight:434.51GSK466317A
CAS:GSK466317A is a GRK2 inhibitor.Formula:C21H16ClF3N4O2Purity:98%Color and Shape:SolidMolecular weight:448.83Anamorelin Fumarate
CAS:Anamorelin Fumarate is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).Formula:C35H46N6O7Purity:98%Color and Shape:SolidMolecular weight:662.78ATC0065
CAS:ATC0065 is a melanin-concentrating hormone receptor 1 antagonist with oral activity.Formula:C25H29BrF3N5OColor and Shape:SolidMolecular weight:552.43Alclofenac lysinate
CAS:Alclofenac is an anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also used as an analgesic and an antipyretic.Formula:C17H25ClN2O5Purity:98%Color and Shape:SolidMolecular weight:372.84Cirazoline hydrochloride
CAS:Cirazoline hydrochloride is a synthetic competitive full agonist of α1A-AR (Ki 120 nM) and partial agonist at α1B-AR and α1D-AR.Formula:C13H17ClN2OPurity:99.863%Color and Shape:SolidMolecular weight:252.74Acetylaszonalenin
CAS:Acetylaszonalenin, from A. flavipes, is an NK1 receptor antagonist with a Ki of 170 μM, blocking substance P.Formula:C25H25N3O3Color and Shape:SolidMolecular weight:415.48SKF83822 hydrobromide
CAS:SKF83822 hydrobromide is a dopamine D1-like receptor agonist.Formula:C20H23BrClNO2Purity:98%Color and Shape:SolidMolecular weight:424.76MRS2603
CAS:MRS2603 is an antagonist of P2Y1 and P2Y13 receptors in 1321N1 human astrocytoma cells.Formula:C14H12ClN4O8PPurity:98%Color and Shape:SolidMolecular weight:430.69Indatraline hydrochloride
CAS:Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET)Formula:C16H16Cl3NPurity:98%Color and Shape:SolidMolecular weight:328.66CAY10498
CAS:A3 AR antagonist CAY10498, with Ki of 37 nM, is 60-200x selective over A1/A2A receptors; no dedifferentiation effects shown.Formula:C18H20N6Color and Shape:SolidMolecular weight:320.39Hexoprenaline
CAS:Hexoprenaline is a stimulant of adrenergic beta 2 receptors used as a bronchodilator, antiasthmatic agent, and tocolytic agent.Formula:C22H32N2O6Color and Shape:SolidMolecular weight:420.5KW-8232
CAS:KW-8232, an orally active anti-osteoporotic agent, reduces the biosynthesis of PGE2[1].Formula:C37H41ClN4O6SColor and Shape:SolidMolecular weight:705.27UCSF648
CAS:UCSF648 (Compound 5A6-48) weakly activates MTNR1A and ADRA2A. UCSF648 is a chemical probe for the serotonin receptor 5-HT 5A [1].Formula:C15H19ClN2O2SColor and Shape:SolidMolecular weight:326.84Org-12962 hydrochloride
CAS:Org-12962 hydrochloride is a 5-HT2C receptor agonist.Formula:C10H12Cl2F3N3Purity:98%Color and Shape:SolidMolecular weight:302.12SKF 77434 hydrobromide
CAS:SKF 77434 hydrobromide is a dopamine D1-like receptor partial agonist.Formula:C19H22BrNO2Purity:98%Color and Shape:SolidMolecular weight:376.29SB269652
CAS:SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor.Formula:C27H30N4OPurity:98%Color and Shape:SolidMolecular weight:426.55LEI 101 hydrochloride
CAS:LEI 101 hydrochloride is potent and selective CB2 partial agonist.Formula:C23H26ClFN4O4SColor and Shape:SolidMolecular weight:508.99AZD-1678
CAS:AZD-1678 is a potent CCR4 receptor antagonist.Formula:C11H8Cl2FN3O3SColor and Shape:SolidMolecular weight:352.17Antiplatelet agent 2
CAS:Antiplatelet agent 2 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies.Formula:C21H24F2N6O4SColor and Shape:SolidMolecular weight:494.51CAY10590
CAS:CAY10590 (GK115) inhibits sPLA2, used in chronic kidney inflammation research.Formula:C21H33NO3Color and Shape:SolidMolecular weight:347.49CP 96345
CAS:CP 96345 is a NK1 receptor antagonist.Formula:C28H32N2OPurity:98%Color and Shape:SolidMolecular weight:412.573-epi-Vitamin D3
CAS:3-epi-Vitamin D3 (Epicholecalciferol), an analogue of Vitamin D3, serves as a Hedgehog pathway inhibitor, exhibiting potency with an IC50 value of 39.2 μM inFormula:C27H44OColor and Shape:SolidMolecular weight:384.64CGP 25454A
CAS:CGP 25454A is a novel and selective antagonist of the presynaptic dopamine autoreceptor.Formula:C15H21Cl2N3O2Color and Shape:SolidMolecular weight:346.25Fenmetozole Tosylate
CAS:Fenmetozole Tosylate , acts as an antidepressant drug. is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor,Formula:C17H18Cl2N2O4SPurity:98%Color and Shape:SolidMolecular weight:417.31TH-162
CAS:TH-162 (R)-PIA is an A1 adenosine receptor agonist with ~100× higher affinity than its (+)-isomer.Formula:C19H23N5O4Color and Shape:SolidMolecular weight:385.42Lu AA 47070
CAS:adenosine A2A receptor antagonistFormula:C17H20F2N3O6PSPurity:98%Color and Shape:SolidMolecular weight:463.39S 14063
CAS:S 14063 is a potent 5-HT1A receptor antagonist devoid of beta-adrenoceptor blocking properties.Formula:C22H29Cl2N3O2SColor and Shape:SolidMolecular weight:470.45GSK-345931A
CAS:GSK-345931A is an EP(1) antagonist with CNS uptake in mice/rats, offering strong pain relief in acute and prolonged inflammation.Formula:C22H19ClNNaO3Color and Shape:SolidMolecular weight:403.834VUF 8430 dihydrobromide
CAS:histamine H4 receptor full agonistFormula:C4H12BrN5SPurity:98%Color and Shape:SolidMolecular weight:242.14RUSKI-201
CAS:RUSKI-201 is the first selective Hedgehog acyltransferase (Hhat) chemical probe in cells.Formula:C20H27N3OSColor and Shape:SolidMolecular weight:357.51R-SKF-38393A HCl
CAS:R(+)-SKF-38393A is a D1 dopamine receptor agonist and also is a more active enantiomer of (±)-SKF-38393A.Formula:C16H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:291.77Undecylenoyl phenylalanine
CAS:<p>Undecylenoyl phenylalanine (Sepiwhite msh QD) is a novel depigmenting agent, which possibly acts as an alpha-melanocyte-stimulating hormone antagonist, thus</p>Formula:C20H29NO3Purity:≥98%Color and Shape:White To Pinkish Solid PowderMolecular weight:331.45WAY 629 hydrochloride
CAS:5-HT2C agonistFormula:C15H19ClN2Purity:98%Color and Shape:SolidMolecular weight:262.78A1AR antagonist 4
CAS:Compound 22: A1AR antagonist, pIC50 5.51, pKi 6.29, potent and selective.Formula:C23H25N3O2Color and Shape:SolidMolecular weight:375.465-Methylurapidil
CAS:5-Methylurapidil is an alpha1A-adrenoceptor antagonist.Formula:C21H31N5O3Purity:98%Color and Shape:SolidMolecular weight:401.5JHW 007 hydrochloride
CAS:JHW 007 hydrochloride is a Dopamine uptake inhibitor.Formula:C24H30ClF2NOPurity:98%Color and Shape:SolidMolecular weight:421.95MRS2179
CAS:MRS2179: P2Y1 antagonist, Kb=100 nM, inactive on P2Y2/4/6 (to 30µM), inhibits ADP-induced platelet changes, prolongs bleeding in rodents.Formula:C11H17N5O9P2Color and Shape:SolidMolecular weight:425.23FR-A 19
CAS:FR-A 19: Histamine H2 agonist, nanomolar inhibition of basophil histamine release; potent anti-allergic.Formula:C25H34Cl3F2N5Color and Shape:SolidMolecular weight:548.93CI 1020
CAS:endothelin-A receptor (ETA) antagonistFormula:C28H26O9Purity:98%Color and Shape:SolidMolecular weight:506.5(S)-Carvedilol
CAS:(S)-Carvedilol is a non-selective β/α-1 blocker.It exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).Formula:C24H26N2O4Purity:98%Color and Shape:Less Crystalline Solid Colourless Crystalline SolidMolecular weight:406.47Ipsapirone
CAS:<p>Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.</p>Formula:C19H23N5O3SPurity:99.51%Color and Shape:SolidMolecular weight:401.48Idremcinal
CAS:Idremcinal is a motilin receptor agonist.Formula:C39H69NO12Color and Shape:SolidMolecular weight:743.96CCG-273463
CAS:<p>CCG-273463: Potent GRK5 inhibitor (IC50: 9 nM), used for researching heart failure, hypertrophy, cancer.</p>Formula:C26H25BrN4O3Color and Shape:SolidMolecular weight:521.41Adenosine receptor inhibitor 1
CAS:Potent, selective adenosine receptor blocker with strong affinity, especially A2A (Ki 68.5 nM). Promising for cancer, neurodegeneration study.Formula:C17H19ClFN5O3Color and Shape:SolidMolecular weight:395.82A-123189
CAS:A-123189 is a potent, alpha1D-selective antagonist.Formula:C26H28N4O3SPurity:98%Color and Shape:SolidMolecular weight:476.59DR4485 hydrochloride
CAS:5-HT7 antagonistFormula:C26H29Cl3N2OPurity:98%Color and Shape:SolidMolecular weight:491.88(±)-Befunolol
CAS:(±)-Befunolol is a blocking agent of β-adrenoceptor.Formula:C16H21NO4Purity:98%Color and Shape:SolidMolecular weight:291.34IMMH001
CAS:IMMH001/SYL930: Oral S1P1 receptor agonist; lowers IL-1β, IL-5, IL-18, IP10, CCL3, CCL5; for RA research.Formula:C23H28N2O3Color and Shape:SolidMolecular weight:380.48(E)-Guanabenz
CAS:(E)-Guanabenz is an oral α2-adrenoceptor agonist, antihypertensive, GADD34 inhibitor, and has neuroprotective properties.Formula:C8H8Cl2N4Color and Shape:SolidMolecular weight:231.08AZ-GHS-22
CAS:AZ-GHS-22, an inverse agonist for GHS-R1a (ghrelin receptor), binds with 0.77 nM IC50, cutting mice food intake by 54% at 100 mg/kg.Formula:C27H33ClN6O5S2Color and Shape:SolidMolecular weight:621.17Ksg 504
CAS:Ksg 504 has superior selectivity and affinity to CCK-A receptors and derived from proglumide.Formula:C31H49N5O8SColor and Shape:SolidMolecular weight:651.81A2ti-2
CAS:A2ti-2: selective A2/S100A10 inhibitor, IC50 230 μM, with antiviral action against HPV16.Formula:C18H18N4O2SPurity:99.98%Color and Shape:SolidMolecular weight:354.43Ref: TM-T36433
1mg97.00€5mg230.00€10mg349.00€25mg680.00€50mg938.00€100mg1,293.00€500mg2,593.00€1mL*10mM (DMSO)255.00€XCC
CAS:XCC is an Adenosine receptor antagonist.Formula:C19H22N4O5Purity:98%Color and Shape:SolidMolecular weight:386.4Oxetorone fumarate
CAS:Oxetorone fumarate is a non-selective, orally active antagonist of serotonin and 5-HT receptors,used for migraine treatment.Formula:C25H25NO6Purity:99.809%Color and Shape:SolidMolecular weight:435.48Atigliflozin
CAS:Atigliflozin is an antihyperglycaemic drug candidate.Formula:C18H22O7SColor and Shape:SolidMolecular weight:382.43Ro 363 hydrochloride
CAS:Ro 363 hydrochloride: selective β1-adrenoceptor agonist, boosts heart contraction, lowers diastolic pressure.Formula:C19H26ClNO6Color and Shape:SolidMolecular weight:399.87CB1/2 agonist 4
CAS:CB1/2 agonist 4 is a potent CB1 full agonist (EC50: 15.09 nM) and CB2 partial agonist (EC50: 1.16 nM), with anti-pain and TRPV1 activation properties.Formula:C27H45NO3Color and Shape:SolidMolecular weight:431.65LUF 6283
CAS:partial agonist of hydroxycarboxylic acid receptor 2 (HCA2)Formula:C8H12N2O2Color and Shape:SolidMolecular weight:168.19FG-5893
CAS:FG-5893 is a 5-HT1A agonist and 5-HT2 antagonist with potential anxiolytic activity.Formula:C27H29F2N3O2Purity:98%Color and Shape:SolidMolecular weight:465.53PD-156707
CAS:PD-156707 is a selective antagonist of endothelin A receptor.Formula:C28H26NaO9Purity:98%Color and Shape:SolidMolecular weight:529.497ZCZ011
CAS:ZCZ011 enhances CB1 receptor effects, crosses blood-brain barrier, and potentiates cannabimimetic behaviors in mice.Formula:C21H18N2O2SPurity:98%Color and Shape:SolidMolecular weight:362.44S1P1 Agonist III
CAS:S1P1 Agonist III is an orally active S1P1 receptor agonist (EC₅₀ = 18 nM) with applications in inflammation, immunology, and receptor signaling studies.Formula:C21H16F3N3O3Purity:99.08%Color and Shape:SolidMolecular weight:415.37Octoclothepin maleate salt
CAS:Octoclothepin maleate salt is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist.Formula:C23H25ClN2O4SColor and Shape:SolidMolecular weight:460.97Clovoxamine
CAS:Clovoxamine fumarate (DU 23811 fumarate) is a 5-HT reuptake, serotonin and norepinephrine inhibitor with antidepressant and anticonvulsant activity.Formula:C14H21ClN2O2Purity:99.44% - 99.75%Color and Shape:SolidMolecular weight:284.78HEAT hydrochloride
CAS:HEAT hydrochloride is an α1-adrenoceptor antagonist.Formula:C19H22ClNO2Purity:98%Color and Shape:SolidMolecular weight:331.84TSHR antagonist S37a
CAS:TSHR antagonist S37a is a selective, orally bioavailable TSHR antagonist that inhibits TSH-induced cAMP in TSHR-expressing HEK 293 cells.Formula:C25H20N2O3S2Purity:98%Color and Shape:SolidMolecular weight:460.57Ref: TM-T13217
1mg162.00€5mg389.00€10mg604.00€25mg1,175.00€50mg1,696.00€100mg2,480.00€1mL*10mM (DMSO)396.00€CAD031
CAS:CAD031, a more active derivative of the Alzheimer's disease (AD) targeting agent J147, exhibits neuroprotective and memory-enhancing properties.Formula:C18H14F6N2O2Color and Shape:SolidMolecular weight:404.31ICI 192605
CAS:ICI 192605 is a potent thromboxane A2 receptor (TP receptor) antagonist.Formula:C22H23ClO5Color and Shape:SolidMolecular weight:402.87AL-3138
CAS:AL-3138 is a prostaglandin F2alpha (PGF2alpha) analogue which antagonizes FP prostanoid receptor-mediated inositol phosphates generation.Formula:C20H33FO4Color and Shape:SolidMolecular weight:356.47Guanoxabenz
CAS:Guanoxabenz is an α2 adrenergic receptor agonist.Formula:C8H8Cl2N4OPurity:98%Color and Shape:SolidMolecular weight:247.08RTI 336
CAS:RTI 336 is used as a chronic brain dopamine transporter (DAT) inhibitor.Formula:C24H26Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:429.38L-826266
CAS:L-826266 is an antagonist of EP(1) receptor.Formula:C27H21BrClNO4SColor and Shape:SolidMolecular weight:570.88Ampreloxetine
CAS:Ampreloxetine (TD-9855) is a norepinephrine reuptake inhibitor used to study neurological diseases.Formula:C18H18F3NOPurity:98%Color and Shape:SolidMolecular weight:321.34LY314228
CAS:LY314228 is an antagonist of 5-HT2A receptor.Formula:C20H24N4O3Color and Shape:SolidMolecular weight:368.43Bavisant dihydrochloride
CAS:Bavisant (JNJ-310010740) is an oral, selective H3 receptor antagonist enhancing wakefulness and cognition.Formula:C19H29Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:402.36PQ-69
CAS:PQ-69 is a selective adenosine A1 receptor antagonist with inverse agonist activity.Formula:C20H19FN4OColor and Shape:SolidMolecular weight:350.39Autotaxin-IN-6
CAS:Autotaxin-IN-6 is a strong ATX inhibitor with a 30 nM IC50, potentially aiding anticancer research by hindering cell migration.Formula:C35H54BNO6Color and Shape:SolidMolecular weight:595.62Izuforant
CAS:Izuforant (JW1601) has anti-inflammatory effects, binds h5-HT3R (IC50: 9.1 μM), and blocks H4R orally (IC50: 36 nM).Formula:C12H12BrN7Color and Shape:SolidMolecular weight:334.17Methyldopate hydrochloride
CAS:Methyldopate HCl is an agent of antihypertensive.Formula:C12H18ClNO4Color and Shape:SolidMolecular weight:275.73Denopamine
CAS:Denopamine is an agonist of 1-Adrenoceptor.Formula:C18H23NO4Color and Shape:SolidMolecular weight:317.38GT 2016
CAS:GT 2016 is a H3 receptor antagonist.Formula:C19H31N3OPurity:98%Color and Shape:SolidMolecular weight:317.47CCK-B Receptor Antagonist 2
CAS:CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).Formula:C27H28N6O3Color and Shape:SolidMolecular weight:484.55Fluprostenol methyl ester
CAS:Fluprostenol, a vet-approved luteolytic, has an isopropyl ester, travoprost, used as an eye pressure reducer. CAY10532 is its methyl ester form.Formula:C24H31F3O6Color and Shape:SolidMolecular weight:472.49Blonanserin HCl
CAS:Blonanserin is an antagonist of dopamine-D2 and serotonin-S2.Formula:C23H32Cl2FN3Purity:98%Color and Shape:SolidMolecular weight:440.42SB 207710
CAS:SB 207710 is a selective and high affinity antagonist of 5-HT4 receptor.Formula:C19H27IN2O4Color and Shape:SolidMolecular weight:474.33SEP-363856
CAS:SEP-363856, a non-D2/5-HT2A, orally active CNS psychotropic may treat schizophrenia.Formula:C9H13NOSPurity:98%Color and Shape:SolidMolecular weight:183.27Roxindole hydrochloride
CAS:Dopamine D2 autoreceptor agonistFormula:C23H27ClN2OPurity:98%Color and Shape:SolidMolecular weight:382.935-trans-Prostaglandin E2
CAS:5-trans-PGE2 speeds up fibrinolysis, boosts tissue-PA mediated plasminogen activation, and blocks platelet clumping in human PRP.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.47QCC-374
CAS:QCC-374 is a prostanoid agonist. It potentially for the treatment of pulmonary arterial hypertension.Formula:C28H33N3O2Purity:98%Color and Shape:SolidMolecular weight:443.58UK 1745
CAS:UK 1745 is a novel drug of cardiotonic.Formula:C16H23ClN2O2Color and Shape:SolidMolecular weight:310.82Fluphenazine Decanoate Dihydrochloride
CAS:Fluphenazine Decanoate Dihydrochloride: antipsychotic that blocks D2 dopamine receptors in brain regions.Formula:C32H46Cl2F3N3O2SPurity:98%Color and Shape:SolidMolecular weight:664.69Zenidolol
CAS:Zenidolol (ICI-118551) is a β2 adrenoceptor blocker with K i values: β2 (0.7 nM), β1 (49.5 nM), β3 (611 nM); used in eye disease research.Formula:C17H27NO2Color and Shape:SolidMolecular weight:277.4PD168,077
CAS:PD168,077 is an agonist of dopamine D4 receptor. It has a facilitatory effect on memory consolidation.Formula:C20H22N4OPurity:98%Color and Shape:SolidMolecular weight:334.41PGD2-IN-1
CAS:PGD2-IN-1 (PGD2-inhibitor) is an effective DP receptor antagonist (IC50:0.3 nM), a compound that can inhibit prostaglandin D2 (PGD2) signaling.Formula:C23H23Cl2N3O3Purity:98.21%Color and Shape:SolidMolecular weight:460.35Ref: TM-T4624
1mg70.00€5mg159.00€10mg259.00€25mg437.00€50mg643.00€100mg914.00€500mg1,833.00€1mL*10mM (DMSO)168.00€Arbutamine hydrochloride
CAS:Arbutamine hydrochloride is a catecholamine which acts as a cardiac stimulant.Formula:C18H24ClNO4Color and Shape:SolidMolecular weight:353.84Guanethidine
CAS:Guanethidine sulphate, made in 1959, lowers blood pressure by disrupting neurotransmitters in sympathetic nerves.Formula:C10H22N4Color and Shape:SolidMolecular weight:198.31EP4 receptor antagonist 4
CAS:EP4 receptor antagonist 4 is an agonist of EP4 receptor (human pEC 50 = 6.3) [1].Formula:C19H14N2OSColor and Shape:SolidMolecular weight:318.39Ridazolol
CAS:Ridazolol is a vasodilating and cardioselective beta adrenergic blocker.Formula:C15H18Cl2N4O3Purity:99.05%Color and Shape:SolidMolecular weight:373.23Nafadotride
CAS:Nafadotride is a dopamine D3 receptor antagonist.Formula:C22H27N3O2Color and Shape:SolidMolecular weight:365.47Midodrine D6 hydrochloride
CAS:Midodrine D6 hydrochloride is a vasopressor/antihypotensive agent.Formula:C12H19ClN2O4Purity:98%Color and Shape:SolidMolecular weight:296.78SKF-75670 Hydrobromide
CAS:SKF-75670 hydrobromide is an atypical D1DR (dopamine receptor) agonist. It displays agonist activity in vivo and antagonist activity in vitro.Formula:C17H20BrNO2Color and Shape:SolidMolecular weight:350.25Zicronapine
CAS:Zicronapine (LU 31-130), an atypical antipsychotic with monoaminergic action, targets dopamine D1/D2 and serotonin 5HT2A.Formula:C22H27ClN2Color and Shape:SolidMolecular weight:354.92S-1-Propenyl-L-cysteine
CAS:S-1-Propenyl-L-cysteine, a stereoisomer of S-allyl-l-cysteine, exhibits immunomodulatory effects and has been shown to decrease blood pressure in hypertensiveFormula:C6H11NO2SPurity:98%Color and Shape:SolidMolecular weight:161.22A 55453
CAS:A 55453 is a radiated ionophore used as a reversibl, high-affinity alpha 1-adrenergic receptor probe.Formula:C25H32N6O3Color and Shape:SolidMolecular weight:464.56EP1-antagonist-1
CAS:EP1-antagonist-1 (EP1 antagonist 1) is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).Formula:C19H15BrCl2N2O3Purity:97.06%Color and Shape:SolidMolecular weight:470.14JTC-017
CAS:JTC-017 is an antagonist of Corticotropin-releasing hormone receptor 1.Formula:C20H25Cl2N3O5SColor and Shape:SolidMolecular weight:490.4FRG8701
CAS:FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.Formula:C22H30N2O4SPurity:98%Color and Shape:SolidMolecular weight:418.555-HT7 agonist 1
CAS:<p>5-HT7 agonist 1 (4-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-1H-indole) is a selective agonist of 5-HT7 (IC50 = 222.93 nM).</p>Formula:C19H20ClN3Purity:98.61%Color and Shape:SolidMolecular weight:325.84NAEPA
CAS:NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor.Formula:C20H40NO5PPurity:98%Color and Shape:SolidMolecular weight:405.51JPC-211
CAS:JPC-211 is an agonist of dopamine-receptor.Formula:C17H27NO2Purity:98%Color and Shape:SolidMolecular weight:277.4EP2 receptor antagonist-1
CAS:EP2 receptor antagonist-1: reversible, potent, depends on agonist; anti-inflammatory.Formula:C24H22N4O5Color and Shape:SolidMolecular weight:446.46RXFP3 agonist 1
CAS:RXFP3 agonist 1 is a nonpeptide RXFP3 agonist ( EC 50 =6937 nM) [1].Formula:C18H18ClN5Color and Shape:SolidMolecular weight:339.82A1AR antagonist 2
CAS:Compound 18h is a potent A1 adenosine receptor blocker with Ki of 1.49 nM for hA1, 10.2 nM for hA2A, 50.1 nM for hA2B.Formula:C17H12N4OColor and Shape:SolidMolecular weight:288.3BMS-192364
CAS:BMS-192364 is a bio-active chemical.Formula:C15H9ClF3N3O2Color and Shape:SolidMolecular weight:355.70hBChE-IN-2
CAS:<p>hBChE-IN-2 is a BChE inhibitor and CB2R agonist with neuroprotective activity for the study of Alzheimer's disease-like neurological disorders.</p>Formula:C27H36N4O3Purity:99.60% - 99.83%Color and Shape:SoildMolecular weight:464.6WB403
CAS:WB403 activates TGR5, lowers fasting/postprandial glucose and HbA1c, enhances glucose tolerance, and normalizes pancreatic α/β-cells in diabetic mice.Formula:C19H19BrN2OSPurity:98%Color and Shape:SolidMolecular weight:403.34SKF-82958
CAS:SKF 82958 is a D1/D5 receptor full agonist.Formula:C19H20ClNO2Purity:98%Color and Shape:SolidMolecular weight:329.82Sulfisoxazole diethanolamine
CAS:Sulfisoxazole diethanolamine: a sulfonamide antibacterial, endothelin receptors A and B antagonist, inhibits breast cancer exosomes.Formula:C15H24N4O5SColor and Shape:SolidMolecular weight:372.44PD-135666
CAS:PD-135666 is an antagonist of CCK receptor.Formula:C33H39N3O5Purity:98%Color and Shape:SolidMolecular weight:557.68Isoetharine
CAS:Isoetharine is a selective agonist of β2-adrenergic receptor used as a bronchodilator for emphysema, bronchitis, and asthma.Formula:C13H21NO3Color and Shape:SolidMolecular weight:239.31Modipafant
CAS:Modipaafant is a potent dihydropyridine PAF (platelet activating factor) antagonist.Formula:C34H29ClN6O3Color and Shape:SolidMolecular weight:605.09UCM710
CAS:UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).Formula:C19H34O3Purity:98%Color and Shape:SolidMolecular weight:310.47Fenmetozole HCl
CAS:Fenmetozole HCl is an antagonist of the actions of ethanol. It attenuates the ethanol-induced reduction in cerebellar cyclic guanosine monophosphate content.Formula:C10H11Cl3N2OPurity:98%Color and Shape:SolidMolecular weight:281.57MRGPRX4 modulator-1
CAS:MRGPRX4 modulator-1 (compound 31-2), potent MRGPR X4 antagonist, IC50 < 100nM, for itch, pain, autoimmune research.Formula:C16H13ClF3NO3Color and Shape:SolidMolecular weight:359.73L-733060 hydrochloride
CAS:<p>Potent NK1 antagonist</p>Formula:C20H20ClF6NOPurity:98%Color and Shape:SolidMolecular weight:439.82LY 344864 hydrochloride
CAS:<p>LY 344864 hydrochloride is a selective receptor agonist with an affinity of 6 nM (Ki) at the 5-HT1F receptor.</p>Formula:C21H23ClFN3OColor and Shape:SolidMolecular weight:387.88LY377604
CAS:LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM) and β1/2-adrenergic receptor antagonist for the study of obesity.Formula:C31H32N4O4Purity:99.72% - >99.99%Color and Shape:SolidMolecular weight:524.61Imnopitant
CAS:Imnopitant is an antagonist of the NK1 receptor [1].Formula:C28H28F6N4OColor and Shape:SolidMolecular weight:550.54Dopamine D2 receptor antagonist-1
CAS:Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.Formula:C14H17N3SPurity:99.86%Color and Shape:SolidMolecular weight:259.37Ref: TM-T11077
1mg60.00€5mg127.00€10mg188.00€25mg354.00€50mg518.00€100mg730.00€1mL*10mM (DMSO)140.00€MK-4256
CAS:MK-4256 is an effective and selective SSTR3 antagonist (IC50s: 0.66 nM and 0.36 nM in human and mouse receptor binding assays, respectively).Formula:C27H23FN8OColor and Shape:SolidMolecular weight:494.52S-777469
CAS:S-777469: Selective CB2 agonist, oral, inhibits itching in mice (Ki: 36 nM). Anti-pruritic.Formula:C23H27FN2O4Color and Shape:SolidMolecular weight:414.47CB2 receptor agonist 3
CAS:GP 2A is a selective agonist of CB2 receptor.Formula:C24H23Cl2N3OColor and Shape:SolidMolecular weight:440.36ATL-801
CAS:ATL-801 is anselective antagonist of A2B receptor with herapeutic activity for colitis.Formula:C24H25N7O3Color and Shape:SolidMolecular weight:459.5L 648051
CAS:L 648051 is a leukotriene D4 receptor antagonist.Formula:C24H28O8SPurity:98%Color and Shape:SolidMolecular weight:476.54JNJ-28610244
CAS:JNJ-28610244 is a specific agonist of the H4 receptor. It acts by blocking Mac-1-dependent activation of p38 MAPK.Formula:C16H21N3OPurity:98%Color and Shape:SolidMolecular weight:271.36Talipexole
CAS:Talipexole (B-HT920) is an agonist of dopamine, and is an antiparkinsonian agent.Formula:C10H15N3SPurity:98%Color and Shape:SolidMolecular weight:209.31UR-PI376
CAS:UR-PI376 is a selective histamine H4 receptor agonist with low H1/H2 activity and moderate H3 affinity.Formula:C17H22N6SColor and Shape:SolidMolecular weight:342.46VSN-16
CAS:VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis.Formula:C18H26N2O3Color and Shape:SolidMolecular weight:318.41Setastine
CAS:Setastine, a highly selective H1 receptor antagonist, acts as a non-sedative antihistamine.Formula:C22H28ClNOColor and Shape:SolidMolecular weight:357.92PF 03654746 FA
PF 03654746 FA is a human histamine receptor H(3) antagonist that can be used to study cognitive impairment and Alzheimer's disease.Formula:C19H26F2N2O3Purity:99.44%Color and Shape:SoildMolecular weight:368.42Ziprasidone mesylate trihydrate
CAS:Ziprasidone mesylate hydrate is an oral 5-HT/D2 antagonist with Ki: D2=4.8nM, 5-HT2A=0.42nM, 5-HT1A=3.4nM in rats.Formula:C22H31ClN4O7S2Color and Shape:SolidMolecular weight:563.08Nebidrazine
CAS:Nebidrazine is an alpha-adrenoceptor agonist.Formula:C9H8Cl2N6Color and Shape:SolidMolecular weight:271.11Veliflapon
CAS:Veliflapon is an orally active and selective inhibitor of 5-lipoxygenase activating protein (FLAP).Formula:C23H23NO3Purity:98%Color and Shape:SolidMolecular weight:361.43CYM-5478
CAS:CYM-5478, a strong S1P2 agonist, boosts C6 cell survival over 100nM under serum-starvation.Formula:C21H19F3N2O2Purity:98%Color and Shape:SolidMolecular weight:388.38Rec 15/2615 dihydrochloride
CAS:Rec 15/2615 dihydrochloride is an antagonist of α1B-adrenergic receptor.Formula:C26H35Cl2N5O5Purity:97.04% - 99.76%Color and Shape:SolidMolecular weight:568.49BKM-570
CAS:BKM-570, a bradykinin antagonist, causes impressive growth inhibition of lung and prostate tumors.Formula:C34H34Cl2F5N3O3Purity:98%Color and Shape:SolidMolecular weight:698.55Latanoprost ethyl amide
CAS:Lat-NEt, a latanoprost analog, is an ocular hypotensive prodrug with slower hydrolysis, converting to free acids in corneal tissue.Formula:C25H39NO4Color and Shape:SolidMolecular weight:417.58JNJ-10191584
CAS:JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammationFormula:C13H15ClN4OColor and Shape:SolidMolecular weight:278.74Sipagladenant
CAS:Sipagladenant: oral inverse agonist for A2A adenosine receptor, may aid frontal lobe dysfunction research.Formula:C20H19N3O4SColor and Shape:SolidMolecular weight:397.45BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Formula:C24H35ClN2O4Purity:98%Color and Shape:SolidMolecular weight:451GSK-215083
CAS:GSK-215083: a PET quinoline-based 5-HT6 antagonist radioligand, binds 5HT6 in striatum and 5HT2A in frontal cortex.Formula:C20H20FN3O2SColor and Shape:SolidMolecular weight:385.46Remogliflozin
CAS:Remogliflozin is an effective sodium-glucose transporter 2 inhibitor (Kis = 12.4 and 26 nM for human and rat SGLT2, respectively).Formula:C23H34N2O7Color and Shape:SolidMolecular weight:450.53Tetrahydrozoline nitrate
CAS:Tetrahydrozoline, an imidazoline derivative, is an α-adrenergic agonist for nasal and eye congestion studies.Formula:C13H17N3O3Color and Shape:SolidMolecular weight:263.297FR-171113
CAS:Protease-activated receptor 1 antagonistFormula:C19H11Cl3N2O4SPurity:98%Color and Shape:SolidMolecular weight:469.73ADR-851 HCl
CAS:ADR-851 HCl is an HT3 receptor antagonist. It works against mechanical, acute thermal, and formalin-induced inflammatory pain.Formula:C14H19Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:332.23E2508
CAS:E2508 is a selective antagonist of corticotropin-releasing factor 1 receptor.Formula:C36H47N3O7SPurity:98%Color and Shape:SolidMolecular weight:665.84BPIPP
CAS:guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitorFormula:C22H16BrN3O3Purity:98%Color and Shape:SolidMolecular weight:450.28Trimipramine
CAS:Trimipramine is an antidepressant with an anxiety-reducing sedative component to its action.Formula:C20H26N2Purity:98%Color and Shape:SolidMolecular weight:294.43Avosentan
CAS:<p>Avosentan(Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.</p>Formula:C23H21N5O5SPurity:98.31% - 99.47%Color and Shape:SolidMolecular weight:479.51Vestipitant
CAS:Vestipitant (GW597599): a potent NK1 antagonist, may treat anxiety, depression, nausea, tinnitus, insomnia.Formula:C23H24F7N3OColor and Shape:SolidMolecular weight:491.45Zimelidine dihydrochloride
CAS:5-HT re-uptake inhibitorFormula:C16H18BrClN2Purity:98%Color and Shape:SolidMolecular weight:353.69AP-521 (Free base)
CAS:AP-521, a 5-HT1A receptor antagonist, is used potentially for the treatment of anxiety.Formula:C20H18N2O3SColor and Shape:SolidMolecular weight:366.43BRD5814
CAS:BRD5814 is a highly brain penetrant β-arrestin biased D2R antagonist.Formula:C21H23ClF3NO2Color and Shape:SolidMolecular weight:413.86(R)-Carvedilol
CAS:(R)-Carvedilol is a non-selective blocker of β/α-1. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).Formula:C24H26N2O4Purity:98%Color and Shape:SolidMolecular weight:406.47PD 120697
CAS:PD 120697 is a dopamine antagonist with central dopamine agonist properties.Formula:C11H15N3SPurity:98%Color and Shape:SolidMolecular weight:221.32N-0861 racemate
CAS:N-0861 racemate is the racemate of N-0861.Formula:C13H17N5Purity:98%Color and Shape:SolidMolecular weight:243.31Alimemazine
CAS:Alimemazine, an antipruritic and HA-receptor antagonist, also partially activates H1R and other GPCRs.Formula:C18H22N2SPurity:98%Color and Shape:Crystals SolidMolecular weight:298.45Tropodifene
CAS:Tropodifene is an inhibitor of the α-Adrenergic receptor.Formula:C25H29NO4Purity:98%Color and Shape:SolidMolecular weight:407.5FR 139317
CAS:highly potent and selective ETA endothelin receptor antagonistFormula:C33H44N6O5Purity:98%Color and Shape:SolidMolecular weight:604.74PD-159020
CAS:PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).Formula:C32H25NO8Purity:98%Color and Shape:SolidMolecular weight:551.54Befetupitant
CAS:Befupupitant(Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization.Formula:C29H29F6N3O2Purity:98.72%Color and Shape:SolidMolecular weight:565.55S-22153
CAS:S22153 is an antagonist of melatonin receptor.Formula:C14H17NOSColor and Shape:SolidMolecular weight:247.36GR 128107
CAS:GR 128107 is an antagonist of melatonin receptor.Formula:C16H20N2O2Color and Shape:SolidMolecular weight:272.34HAMI 3379
CAS:HAMI 3379 (HAMI3379) is a CysLT2 antagonist that attenuates brain damage and inhibits microglia inflammation following focal cerebral ischemia in rats.Formula:C34H45NO8Purity:99.75%Color and Shape:SolidMolecular weight:595.72Medroxalol
CAS:Medroxalol (RMI81968), an oral α- & β-adrenergic blocker, has antihypertensive and vasodilatory effects.Formula:C20H24N2O5Color and Shape:SolidMolecular weight:372.422-Methylthio-AMP diTEA
CAS:2-MeSAMP diTEA blocks P2Y12 receptor, inhibits ADP platelet clumping.Formula:C23H46N7O7PSColor and Shape:SolidMolecular weight:595.69Falintolol, (Z)-
CAS:Falintolol, (Z)-, is a novel β-adrenergic antagonist compound distinguished by the inclusion of an oxime moiety.Formula:C12H24N2O2Purity:98%Color and Shape:SolidMolecular weight:228.33Benzamide Derivative 1
CAS:Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.Formula:C22H34ClN3O3Purity:>99.99%Color and Shape:SolidMolecular weight:423.98Clenproperol
CAS:Clenproperol is a β2-adrenergic agonist.Formula:C11H16Cl2N2OColor and Shape:SolidMolecular weight:263.16GPR183-IN-2
CAS:<p>GPR183-IN-2 (compound 23) is an effective, orally active inhibitor of GPR183, displaying an IC50 value of 39.45 nM in Ca2+ mobilization assays. This compound has potential applications in research related to cancer, autoimmune diseases, pain, and osteoporosis.</p>Formula:C19H23BrN2O3Color and Shape:SolidMolecular weight:407.3PF-04628935
CAS:PF-04628935: potent GHS-R1a antagonist/inverse agonist, IC50=4.6 nM, orally bioavailable, brain penetrant.Formula:C24H26ClN7OSPurity:98%Color and Shape:SolidMolecular weight:496.03LY 290324
CAS:LY 290324 is an orally active, potent and selective antagonist of cysteinyl leukotriene (LTD4) receptor.Formula:C29H24Cl2N6Purity:98%Color and Shape:SolidMolecular weight:527.45OUP-186
CAS:OUP-186 is a selective H3 receptor antagonist that suppresses breast cancer cell growth with an IC50 of ~50 μM and induces apoptosis.Formula:C19H30ClN3SColor and Shape:SolidMolecular weight:367.98SKI 5C
CAS:SKI 5C is a selective inhibitor of Sphingosine Kinase 1.Formula:C26H45NO4Purity:98%Color and Shape:SolidMolecular weight:435.648-M-PDOT
CAS:8-M-PDOT (AH-002) is an MT2 receptor agonist that inhibits MT1.8-M-PDOT has anxiolytic activity and may be used in the study of neuropathic pain.Formula:C14H19NO2Purity:99.54% - 99.54%Color and Shape:SolidMolecular weight:233.31(2R,3R)-E1R
CAS:(2R,3R)-E1R is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders.Formula:C13H16N2O2Purity:98%Color and Shape:SolidMolecular weight:232.28Prostaglandin D2
CAS:<p>Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals,and is a potent endogenous sleep promoting substances.</p>Formula:C20H32O5Purity:>99.99%Color and Shape:SolidMolecular weight:352.47Guanadrel
CAS:Guanadrel is an antihypertensive agent.Formula:C10H19N3O2Purity:98%Color and Shape:SolidMolecular weight:213.28EMD 386088 hydrochloride
CAS:EMD 386088 hydrochloride is a 5-HT6 receptor agonist.Formula:C14H16Cl2N2Purity:98%Color and Shape:SolidMolecular weight:283.2Zinterol
CAS:<p>Zinterol is a potent and selective agonist of β2-adrenoceptor. Zinterol increases ICa in a concentration-dependent manner(EC50 of 2.2 nM).</p>Formula:C19H26N2O4SPurity:98%Color and Shape:SolidMolecular weight:378.49Mezilamine
CAS:Mezilamine is an antagonist of dopamine. It also blocks presynaptic but stimulating postsynaptic alpha-adrenoceptors.Formula:C11H18ClN5SPurity:98%Color and Shape:SolidMolecular weight:287.81LG 82-4-01
CAS:LG 82-4-01 is an inhibitor of thromboxane (TX) synthetase.Formula:C10H10Cl2N2O3SPurity:98%Color and Shape:SolidMolecular weight:309.17GP531
CAS:GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37A412997
CAS:A412997 is a selective agonist of dopamine D4 receptor.Formula:C19H23N3OPurity:98%Color and Shape:SolidMolecular weight:309.41TC-G1003
CAS:TC-G1003 is an effective agonist of the somatostatin sst2 receptor.Formula:C26H25ClN2O2Purity:98%Color and Shape:SolidMolecular weight:432.94U-101958 Maleate
CAS:U-101958 Maleate binds to dopamine D4 and sigma1 receptors with high affinity in neuroblastoma cells and human cerebellum.Formula:C25H33N3O5Purity:98%Color and Shape:SolidMolecular weight:455.55(4-Acetamidocyclohexyl) nitrate
CAS:(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.Formula:C8H14N2O4Purity:98%Color and Shape:SolidMolecular weight:202.21GTS-21
CAS:GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.Formula:C19H20N2O2Purity:98%Color and Shape:SolidMolecular weight:308.37
