
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(985 products)
- Adenosine Receptor(244 products)
- Adrenergic Receptor(2,991 products)
- Bombesin Receptor(32 products)
- Bradykinin Receptor(59 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(209 products)
- Dopamine Receptor(433 products)
- Endothelin Receptor(79 products)
- GNRH Receptor(77 products)
- GPCR19(32 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(181 products)
- Hedgehog/Smoothened(46 products)
- Histamine Receptor(380 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(309 products)
- PAFR(12 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5696 products of "GPCR/G-Protein"
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Falintolol
CAS:<p>Falintolol is a novel beta-adrenergic antagonist with antihypertensive effects and can be used to study glaucoma.</p>Formula:C12H24N2O2Purity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:228.33Rolapitant
CAS:<p>Rolapitant Hydrochloride is an oral NK1-receptor blocker that prevents nausea and has a fast onset and long half-life.</p>Formula:C25H26F6N2O2Purity:99.86%Color and Shape:SolidMolecular weight:500.48MRE3008F20
CAS:MRE3008F20 is an AA3R antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used to study glaucoma and asthma.Formula:C21H20N8O3Purity:97.29%Color and Shape:SolidMolecular weight:432.44(±)-Befunolol
CAS:(±)-Befunolol is a blocking agent of β-adrenoceptor.Formula:C16H21NO4Purity:98%Color and Shape:SolidMolecular weight:291.34A-123189
CAS:<p>A-123189 is a potent, alpha1D-selective antagonist.</p>Formula:C26H28N4O3SPurity:98%Color and Shape:SolidMolecular weight:476.59IMMH001
CAS:<p>IMMH001/SYL930: Oral S1P1 receptor agonist; lowers IL-1β, IL-5, IL-18, IP10, CCL3, CCL5; for RA research.</p>Formula:C23H28N2O3Color and Shape:SolidMolecular weight:380.48A2ti-2
CAS:<p>A2ti-2: selective A2/S100A10 inhibitor, IC50 230 μM, with antiviral action against HPV16.</p>Formula:C18H18N4O2SPurity:98.31%Color and Shape:SolidMolecular weight:354.43Clovoxamine
CAS:Clovoxamine fumarate (DU 23811 fumarate) is a 5-HT reuptake, serotonin and norepinephrine inhibitor with antidepressant and anticonvulsant activity.Formula:C14H21ClN2O2Purity:99.44% - 99.75%Color and Shape:SolidMolecular weight:284.78FR-A 19
CAS:FR-A 19: Histamine H2 agonist, nanomolar inhibition of basophil histamine release; potent anti-allergic.Formula:C25H34Cl3F2N5Color and Shape:SolidMolecular weight:548.93Cinitapride Hydrogen Tartrate
CAS:Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptorsFormula:C25H36N4O10Purity:98%Color and Shape:SolidMolecular weight:552.581Lu AA 47070
CAS:adenosine A2A receptor antagonistFormula:C17H20F2N3O6PSPurity:98%Color and Shape:SolidMolecular weight:463.39CCK-B Receptor Antagonist 2
CAS:CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).Formula:C27H28N6O3Color and Shape:SolidMolecular weight:484.55CAY10590
CAS:CAY10590 (GK115) inhibits sPLA2, used in chronic kidney inflammation research.Formula:C21H33NO3Color and Shape:SolidMolecular weight:347.49Blonanserin HCl
CAS:Blonanserin is an antagonist of dopamine-D2 and serotonin-S2.Formula:C23H32Cl2FN3Purity:98%Color and Shape:SolidMolecular weight:440.42S-1-Propenyl-L-cysteine
CAS:S-1-Propenyl-L-cysteine, a stereoisomer of S-allyl-l-cysteine, exhibits immunomodulatory effects and has been shown to decrease blood pressure in hypertensiveFormula:C6H11NO2SPurity:98%Color and Shape:SolidMolecular weight:161.22RXFP3 agonist 1
CAS:<p>RXFP3 agonist 1 is a nonpeptide RXFP3 agonist ( EC 50 =6937 nM) [1].</p>Formula:C18H18ClN5Color and Shape:SolidMolecular weight:339.82UCSF648
CAS:UCSF648 (Compound 5A6-48) weakly activates MTNR1A and ADRA2A. UCSF648 is a chemical probe for the serotonin receptor 5-HT 5A [1].Formula:C15H19ClN2O2SColor and Shape:SolidMolecular weight:326.84SKF83822 hydrobromide
CAS:SKF83822 hydrobromide is a dopamine D1-like receptor agonist.Formula:C20H23BrClNO2Purity:98%Color and Shape:SolidMolecular weight:424.76SKF-82958
CAS:SKF 82958 is a D1/D5 receptor full agonist.Formula:C19H20ClNO2Purity:98%Color and Shape:SolidMolecular weight:329.82Dopamine D2 receptor antagonist-1
CAS:<p>Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.</p>Formula:C14H17N3SPurity:99.86%Color and Shape:SolidMolecular weight:259.37UR-PI376
CAS:UR-PI376 is a selective histamine H4 receptor agonist with low H1/H2 activity and moderate H3 affinity.Formula:C17H22N6SColor and Shape:SolidMolecular weight:342.46VSN-16
CAS:<p>VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis.</p>Formula:C18H26N2O3Color and Shape:SolidMolecular weight:318.41BKM-570
CAS:<p>BKM-570, a bradykinin antagonist, causes impressive growth inhibition of lung and prostate tumors.</p>Formula:C34H34Cl2F5N3O3Purity:98%Color and Shape:SolidMolecular weight:698.55BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Formula:C24H35ClN2O4Purity:98%Color and Shape:SolidMolecular weight:451GSK-215083
CAS:GSK-215083: a PET quinoline-based 5-HT6 antagonist radioligand, binds 5HT6 in striatum and 5HT2A in frontal cortex.Formula:C20H20FN3O2SColor and Shape:SolidMolecular weight:385.46Anamorelin Fumarate
CAS:Anamorelin Fumarate is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).Formula:C35H46N6O7Purity:98%Color and Shape:SolidMolecular weight:662.78PD 144418
CAS:PD 144418 displays potential antipsychotic activity.Formula:C18H22N2OPurity:98%Color and Shape:SolidMolecular weight:282.38Camicinal
CAS:Camicinal is a selective motilin receptor agonist (pEC50: 7.9).Formula:C25H33FN4OColor and Shape:SolidMolecular weight:424.55Zimelidine dihydrochloride
CAS:5-HT re-uptake inhibitorFormula:C16H18BrClN2Purity:98%Color and Shape:SolidMolecular weight:353.69(R)-Carvedilol
CAS:(R)-Carvedilol is a non-selective blocker of β/α-1. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).Formula:C24H26N2O4Purity:98%Color and Shape:SolidMolecular weight:406.47JNJ 10191584 maleate
CAS:JNJ 10191584 maleate (VUF6002 maleate) is an orally active and selective antagonist of H4 receptor (Ki = 26 nM).Formula:C17H19ClN4O5Purity:99.37%Color and Shape:SolidMolecular weight:394.81Tropodifene
CAS:Tropodifene is an inhibitor of the α-Adrenergic receptor.Formula:C25H29NO4Purity:98%Color and Shape:SolidMolecular weight:407.52-Methylthio-AMP diTEA
CAS:<p>2-MeSAMP diTEA blocks P2Y12 receptor, inhibits ADP platelet clumping.</p>Formula:C23H46N7O7PSColor and Shape:SolidMolecular weight:595.69Falintolol, (Z)-
CAS:Falintolol, (Z)-, is a novel β-adrenergic antagonist compound distinguished by the inclusion of an oxime moiety.Formula:C12H24N2O2Purity:98%Color and Shape:SolidMolecular weight:228.33Mezilamine
CAS:Mezilamine is an antagonist of dopamine. It also blocks presynaptic but stimulating postsynaptic alpha-adrenoceptors.Formula:C11H18ClN5SPurity:98%Color and Shape:SolidMolecular weight:287.81TC-G1003
CAS:TC-G1003 is an effective agonist of the somatostatin sst2 receptor.Formula:C26H25ClN2O2Purity:98%Color and Shape:SolidMolecular weight:432.94Cinalukast
CAS:CysLT1 leukotriene receptor antagonistFormula:C23H28N2O3SPurity:98%Color and Shape:SolidMolecular weight:412.55CCG-4986
CAS:CCG-4986 is the first small molecule RGS inhibitor reported that directly bound to an RGS protein.Formula:C13H11ClN2O5S2Color and Shape:SolidMolecular weight:374.82Way 100289
CAS:Way 100289 is a selective 5-HT3 receptor antagonist.Formula:C20H27N3O3Color and Shape:SolidMolecular weight:357.45VUF 8328
CAS:VUF 8328 is an agonist of histamine H(3) receptor.Formula:C7H12N4SPurity:98%Color and Shape:SolidMolecular weight:184.26CM764
CAS:<p>CM764 is a potent and selective antagonist of sigma-2 receptors, a novel derivative of SN79.</p>Formula:C23H27FN4O3Color and Shape:SolidMolecular weight:426.48GSK1614343
CAS:GSK1614343 is an antagonist of ghrelin receptor.Formula:C22H23F6N5OColor and Shape:SolidMolecular weight:487.44BGC 20-761
CAS:BGC20-761: selective 5-HT6/Dopamine antagonist; enhances memory, potential antipsychotic. K i - 5-HT6: 20 nM, 5-HT2A: 69 nM, D2: 140 nM.Formula:C19H22N2OColor and Shape:SolidMolecular weight:294.39WB 4101 hydrochloride
CAS:α1A-adrenergic antagonistFormula:C19H24ClNO5Purity:98%Color and Shape:SolidMolecular weight:381.85Amitriptylinoxide
CAS:<p>Amitriptylinoxide is an antidepressant.</p>Formula:C20H23NOPurity:98%Color and Shape:SolidMolecular weight:293.4PF-3246799
CAS:<p>PF-3246799 is an effective and selective agonist of the 5-HT2C receptor.</p>Formula:C15H17N3Purity:98%Color and Shape:SolidMolecular weight:239.32Impromidine
CAS:Impromidine is a highly potent and specific agonist of the histamine H2 receptor.Formula:C14H23N7SPurity:98%Color and Shape:SolidMolecular weight:321.44L 665871
CAS:L 665871 is used as a beta-agonist. It works as a potential swine growth promoter.Formula:C11H19N3OPurity:98%Color and Shape:SolidMolecular weight:209.29Azatadine
CAS:Azatadine is histamine and cholinergic inhibitor (IC50: 6.5 nM and 10 nM, respectively).Formula:C20H22N2Purity:98%Color and Shape:SolidMolecular weight:290.4SN 003
CAS:SN 003 is a CRF1 antagonist.Formula:C19H25N5O2Purity:98%Color and Shape:SolidMolecular weight:355.43EPAC 5376753
CAS:<p>EPAC 5376753 is an allosteric inhibitor of EPAC1 with an IC50 of 4 µM in Swiss 3T3 cells.</p>Formula:C15H8Cl2N2O3SPurity:97.48%Color and Shape:SolidMolecular weight:367.21Amibegron hydrochloride
CAS:<p>Amibegron hydrochloride is a selective β3-adrenoceptor agonist (EC50: 3.5 nM for β-adrenoceptor in rat colon). It has anxiolytic and antidepressant activity.</p>Formula:C22H27Cl2NO4Color and Shape:SolidMolecular weight:440.36Sograzepide
CAS:Sograzepide (Netazepide) is a gastrin/CCK-B antagonist, inhibits gastrin/CCK-A activity, and can induce regression of type 1 gastric neuroendocrine tumorsFormula:C28H30N6O3Purity:98%Color and Shape:SolidMolecular weight:498.58MRS-1191
CAS:MRS-1191 is an effective and selective A3 adenosine receptor antagonist (KB: 92 nM, a Ki: 31.4 nM for human A3 receptor and an IC50: 120 nM for CHO cells).Formula:C31H27NO4Color and Shape:SolidMolecular weight:477.55Methiothepin maleate
CAS:<p>Methiothepin maleate (Metitepine) is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.</p>Formula:C24H28N2O4S2Purity:98%Color and Shape:SolidMolecular weight:472.62TAK-220
CAS:TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).Formula:C31H41ClN4O3Purity:98%Color and Shape:SolidMolecular weight:553.14Dopamine D4 receptor antagonist-1
CAS:<p>Dopamine D4 receptor antagonist-1 can be used in schizophrenia study.</p>Formula:C18H19ClN4Color and Shape:SolidMolecular weight:326.82Org37684
CAS:<p>5-HT2 receptors agonist</p>Formula:C14H20ClNO2Purity:98%Color and Shape:SolidMolecular weight:269.77OX2R-IN-1
CAS:<p>OX2R-IN-1: OX2R antagonist, low cytotoxicity, blood-brain barrier permeable, short half-life.</p>Formula:C20H28ClN3O5SColor and Shape:SolidMolecular weight:457.97Prasugrel (Maleic acid)
CAS:<p>Prasugrel Maleic acid: oral P2Y12 antagonist, thienopyridine prodrug, inhibits ADP-induced platelet aggregation.</p>Formula:C24H24FNO7SPurity:98%Color and Shape:SolidMolecular weight:489.51RP 67580
CAS:<p>tachykinin NK1 receptor antagonist</p>Formula:C29H30N2O2Purity:98%Color and Shape:White SolidMolecular weight:438.56Amitifadine hydrochloride
CAS:<p>Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).</p>Formula:C11H12Cl3NPurity:98%Color and Shape:SolidMolecular weight:264.58Piperidine-MO-1
CAS:<p>Piperidine-MO-1 is a dopamine receptor modulator, with an ED50 of 68 μmol/kg on increase of DOPAC in the rat striatum.</p>Formula:C14H21ClFNO2SPurity:99.88%Color and Shape:SolidMolecular weight:321.84GSK 894281
CAS:GSK 894281 is a ghrelin receptor agonist. It may produces myocardial degeneration/necrosis in rats.Formula:C24H28FN3O4SPurity:98%Color and Shape:SolidMolecular weight:473.56CB1R Allosteric modulator 4
CAS:<p>Modulates CB1R positively; inhibits cAMP production; strong β-arrestin-2 recruitment.</p>Formula:C20H17N3O2SColor and Shape:SolidMolecular weight:363.43Tiodazosin
CAS:<p>Tiodazosin is a competitive antagonist of the postsynaptic alpha-adrenergic receptor.</p>Formula:C18H21N7O4SPurity:98%Color and Shape:SolidMolecular weight:431.47MS438
CAS:MS438 is an effective agonist of the TSH receptor.Formula:C20H17F3N2O3Purity:98%Color and Shape:SolidMolecular weight:390.36CGS-12066 maleate salt
CAS:CGS-12066 maleate salt is an agonist of 5-HT1B serotonin receptor.Formula:C21H21F3N4O4Color and Shape:SolidMolecular weight:450.41(4-Acetamidocyclohexyl) nitrate
CAS:<p>(4-Acetamidocyclohexyl) nitrate (BM121307) is an activator of guanylate cyclase.</p>Formula:C8H14N2O4Purity:98%Color and Shape:SolidMolecular weight:202.21Lintopride
CAS:Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.Formula:C14H19ClN4O2Purity:98%Color and Shape:SolidMolecular weight:310.78A412997
CAS:<p>A412997 is a selective agonist of dopamine D4 receptor.</p>Formula:C19H23N3OPurity:98%Color and Shape:SolidMolecular weight:309.41GP531
CAS:<p>GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.</p>Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37LG 82-4-01
CAS:LG 82-4-01 is an inhibitor of thromboxane (TX) synthetase.Formula:C10H10Cl2N2O3SPurity:98%Color and Shape:SolidMolecular weight:309.17CB1-IN-2
CAS:CB1-IN-2 (4g) inhibits CB1 receptor with 0.644 μM IC50; crosses blood-brain barrier, may cause CNS side effects like Rimonabant.Formula:C17H19Cl2N5OColor and Shape:SolidMolecular weight:380.27EMD 386088 hydrochloride
CAS:EMD 386088 hydrochloride is a 5-HT6 receptor agonist.Formula:C14H16Cl2N2Purity:98%Color and Shape:SolidMolecular weight:283.2Guanadrel
CAS:<p>Guanadrel is an antihypertensive agent.</p>Formula:C10H19N3O2Purity:98%Color and Shape:SolidMolecular weight:213.288-M-PDOT
CAS:8-M-PDOT (AH-002) is an MT2 receptor agonist that inhibits MT1.8-M-PDOT has anxiolytic activity and may be used in the study of neuropathic pain.Formula:C14H19NO2Purity:99.54% - 99.54%Color and Shape:SolidMolecular weight:233.31SKI 5C
CAS:SKI 5C is a selective inhibitor of Sphingosine Kinase 1.Formula:C26H45NO4Purity:98%Color and Shape:SolidMolecular weight:435.64LY 290324
CAS:LY 290324 is an orally active, potent and selective antagonist of cysteinyl leukotriene (LTD4) receptor.Formula:C29H24Cl2N6Purity:98%Color and Shape:SolidMolecular weight:527.45ST-198
CAS:ST-198 is a dopamine D3 receptor antagonist.Formula:C22H26N2OPurity:98%Color and Shape:SolidMolecular weight:334.45SR 49059
CAS:vasopressin V1A receptor antagonistFormula:C28H27Cl2N3O7SPurity:98%Color and Shape:SolidMolecular weight:620.5PD-159020
CAS:<p>PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).</p>Formula:C32H25NO8Purity:98%Color and Shape:SolidMolecular weight:551.54BIIL 260
CAS:<p>BIIL 260 is a leukotriene B4 (BLT1) receptor antagonist with anti-inflammatory activity.</p>Formula:C30H30N2O3Color and Shape:SolidMolecular weight:466.57N-0861 racemate
CAS:<p>N-0861 racemate is the racemate of N-0861.</p>Formula:C13H17N5Purity:98%Color and Shape:SolidMolecular weight:243.31PD 120697
CAS:PD 120697 is a dopamine antagonist with central dopamine agonist properties.Formula:C11H15N3SPurity:98%Color and Shape:SolidMolecular weight:221.32Zaltidine
CAS:Zaltidine is an antagonist of H2-receptor, and has the antisecretory action.Formula:C8H10N6SPurity:98%Color and Shape:SolidMolecular weight:222.27(+)-UH 232 maleate
CAS:D2 antagonistFormula:C18H29NOPurity:98%Color and Shape:SolidMolecular weight:275.43Vestipitant
CAS:Vestipitant (GW597599): a potent NK1 antagonist, may treat anxiety, depression, nausea, tinnitus, insomnia.Formula:C23H24F7N3OColor and Shape:SolidMolecular weight:491.45Avosentan
CAS:<p>Avosentan(Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.</p>Formula:C23H21N5O5SPurity:98.31% - 99.47%Color and Shape:SolidMolecular weight:479.51Tetrahydrozoline nitrate
CAS:Tetrahydrozoline, an imidazoline derivative, is an α-adrenergic agonist for nasal and eye congestion studies.Formula:C13H17N3O3Color and Shape:SolidMolecular weight:263.297UCM 707
CAS:endocannabinoid transport inhibitorFormula:C25H37NO2Purity:98%Color and Shape:SolidMolecular weight:383.57SKF 83959 hydrobromide
CAS:SKF 83959 hydrobromide is a Dopamine D1-like receptor partial agonist.Formula:C18H21BrClNO2Purity:98%Color and Shape:SolidMolecular weight:398.72CYM-5478
CAS:CYM-5478, a strong S1P2 agonist, boosts C6 cell survival over 100nM under serum-starvation.Formula:C21H19F3N2O2Purity:98%Color and Shape:SolidMolecular weight:388.38R(+)-6-Bromo-APB HBr
CAS:<p>R(+)-6-Bromo-APB HBr is used as a D1 Dopamine receptor agonist.</p>Formula:C19H21Br2NO2Purity:98%Color and Shape:SolidMolecular weight:455.18Veliflapon
CAS:<p>Veliflapon is an orally active and selective inhibitor of 5-lipoxygenase activating protein (FLAP).</p>Formula:C23H23NO3Purity:98%Color and Shape:SolidMolecular weight:361.43Apadenoson
CAS:<p>Apadenoson: potent A2 agonist, A3 inhibitor (IC 45 nM), anti-inflammatory, for neurological research.</p>Formula:C23H30N6O6Purity:98%Color and Shape:SolidMolecular weight:486.52Setastine
CAS:Setastine, a highly selective H1 receptor antagonist, acts as a non-sedative antihistamine.Formula:C22H28ClNOColor and Shape:SolidMolecular weight:357.92LY 344864 S-enantiomer
CAS:<p>LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist.</p>Formula:C21H22FN3OPurity:98%Color and Shape:SolidMolecular weight:351.42Talipexole
CAS:<p>Talipexole (B-HT920) is an agonist of dopamine, and is an antiparkinsonian agent.</p>Formula:C10H15N3SPurity:98%Color and Shape:SolidMolecular weight:209.31JNJ-28610244
CAS:JNJ-28610244 is a specific agonist of the H4 receptor. It acts by blocking Mac-1-dependent activation of p38 MAPK.Formula:C16H21N3OPurity:98%Color and Shape:SolidMolecular weight:271.36Bopindolol fumarate
CAS:<p>Bopindolol fumarate: non-selective β1/β2-adrenoceptor blocker, partial agonist, low β3 affinity, treats hypertension.</p>Formula:C27H32N2O7Color and Shape:SolidMolecular weight:496.56L 648051
CAS:L 648051 is a leukotriene D4 receptor antagonist.Formula:C24H28O8SPurity:98%Color and Shape:SolidMolecular weight:476.54MK-4256
CAS:MK-4256 is an effective and selective SSTR3 antagonist (IC50s: 0.66 nM and 0.36 nM in human and mouse receptor binding assays, respectively).Formula:C27H23FN8OColor and Shape:SolidMolecular weight:494.52I-SAP
CAS:<p>I-SAP: TP receptor blocker, alters platelet shape without causing clumping, EC50 9.7 nM, max binding pH 6.5-7.4, Kd 468-490 pM.</p>Formula:C22H30INO4SColor and Shape:SolidMolecular weight:531.45LY 344864 hydrochloride
CAS:<p>LY 344864 hydrochloride is a selective receptor agonist with an affinity of 6 nM (Ki) at the 5-HT1F receptor.</p>Formula:C21H23ClFN3OColor and Shape:SolidMolecular weight:387.88L-733060 hydrochloride
CAS:<p>Potent NK1 antagonist</p>Formula:C20H20ClF6NOPurity:98%Color and Shape:SolidMolecular weight:439.82PD-89211
CAS:PD 89211 selectively blocks dopamine D4.2 receptor >800x vs. other subtypes; reverses quinpirole effect in vitro (IC50 = 2.1 nM).Formula:C19H21ClN4OPurity:98%Color and Shape:SolidMolecular weight:356.855-HT6/5-HT2A receptor ligand-1
CAS:<p>Compound 33 is a dual 5-HT6/5-HT2A antagonist with Ki values of 2 nM and 11 nM, respectively, useful in neuro/psychiatric research.</p>Formula:C21H19FN2O2Color and Shape:SolidMolecular weight:350.39MRGPRX4 modulator-1
CAS:<p>MRGPRX4 modulator-1 (compound 31-2), potent MRGPR X4 antagonist, IC50 < 100nM, for itch, pain, autoimmune research.</p>Formula:C16H13ClF3NO3Color and Shape:SolidMolecular weight:359.73Fenmetozole HCl
CAS:Fenmetozole HCl is an antagonist of the actions of ethanol. It attenuates the ethanol-induced reduction in cerebellar cyclic guanosine monophosphate content.Formula:C10H11Cl3N2OPurity:98%Color and Shape:SolidMolecular weight:281.57UCM710
CAS:UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).Formula:C19H34O3Purity:98%Color and Shape:SolidMolecular weight:310.47BMS-192364
CAS:<p>BMS-192364 is a bio-active chemical.</p>Formula:C15H9ClF3N3O2Color and Shape:SolidMolecular weight:355.70A1AR antagonist 2
CAS:Compound 18h is a potent A1 adenosine receptor blocker with Ki of 1.49 nM for hA1, 10.2 nM for hA2A, 50.1 nM for hA2B.Formula:C17H12N4OColor and Shape:SolidMolecular weight:288.3JPC-211
CAS:<p>JPC-211 is an agonist of dopamine-receptor.</p>Formula:C17H27NO2Purity:98%Color and Shape:SolidMolecular weight:277.4Pridefine
CAS:Pridefine: antidepressant, balances serotonin, dopamine, norepinephrine reuptake, weakly releases them.Formula:C19H21NPurity:99.15% - 99.66%Color and Shape:SolidMolecular weight:263.38CL-216303 HCl
CAS:CL-216303 HCl, a dopamine transporter inhibitor and a 5-HT inhibitor, is used potentially for the treatment of depression.Formula:C11H12Cl3NPurity:98%Color and Shape:SolidMolecular weight:264.58Midodrine D6 hydrochloride
CAS:Midodrine D6 hydrochloride is a vasopressor/antihypotensive agent.Formula:C12H19ClN2O4Purity:98%Color and Shape:SolidMolecular weight:296.78Nafadotride
CAS:<p>Nafadotride is a dopamine D3 receptor antagonist.</p>Formula:C22H27N3O2Color and Shape:SolidMolecular weight:365.47Ridazolol
CAS:<p>Ridazolol is a vasodilating and cardioselective beta adrenergic blocker.</p>Formula:C15H18Cl2N4O3Purity:99.05%Color and Shape:SolidMolecular weight:373.23ZK-90055 hydrochloride
CAS:ZK-90055 hydrochloride is a β2 adrenergic receptor agonist used to study asthma.Formula:C16H23ClN2O4Purity:99.26%Color and Shape:SolidMolecular weight:342.82PD168,077
CAS:<p>PD168,077 is an agonist of dopamine D4 receptor. It has a facilitatory effect on memory consolidation.</p>Formula:C20H22N4OPurity:98%Color and Shape:SolidMolecular weight:334.41Fluphenazine Decanoate Dihydrochloride
CAS:<p>Fluphenazine Decanoate Dihydrochloride: antipsychotic that blocks D2 dopamine receptors in brain regions.</p>Formula:C32H46Cl2F3N3O2SPurity:98%Color and Shape:SolidMolecular weight:664.69Roxindole hydrochloride
CAS:Dopamine D2 autoreceptor agonistFormula:C23H27ClN2OPurity:98%Color and Shape:SolidMolecular weight:382.93Oxiperomide
CAS:Oxiperomide is a dopamine D2 and muscarinic M1 receptor ligand. It also has putative antipsychotic and pro-cognitive potential.Formula:C20H23N3O2Purity:98%Color and Shape:SolidMolecular weight:337.42Glucagon receptor antagonists-2
CAS:Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist.Formula:C22H30FNO2Purity:98%Color and Shape:SolidMolecular weight:359.48GT 2016
CAS:GT 2016 is a H3 receptor antagonist.Formula:C19H31N3OPurity:98%Color and Shape:SolidMolecular weight:317.47Guanoxabenz
CAS:Guanoxabenz is an α2 adrenergic receptor agonist.Formula:C8H8Cl2N4OPurity:98%Color and Shape:SolidMolecular weight:247.08TSHR antagonist S37a
CAS:TSHR antagonist S37a is a selective, orally bioavailable TSHR antagonist that inhibits TSH-induced cAMP in TSHR-expressing HEK 293 cells.Formula:C25H20N2O3S2Purity:98%Color and Shape:SolidMolecular weight:460.57JNJ-10191584
CAS:JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammationFormula:C13H15ClN4OColor and Shape:SolidMolecular weight:278.74LUF 6283
CAS:partial agonist of hydroxycarboxylic acid receptor 2 (HCA2)Formula:C8H12N2O2Color and Shape:SolidMolecular weight:168.19CB1/2 agonist 4
CAS:<p>CB1/2 agonist 4 is a potent CB1 full agonist (EC50: 15.09 nM) and CB2 partial agonist (EC50: 1.16 nM), with anti-pain and TRPV1 activation properties.</p>Formula:C27H45NO3Color and Shape:SolidMolecular weight:431.65Oxetorone fumarate
CAS:<p>Oxetorone fumarate is a non-selective, orally active antagonist of serotonin and 5-HT receptors,used for migraine treatment.</p>Formula:C25H25NO6Purity:99.809%Color and Shape:SolidMolecular weight:435.48Alimemazine
CAS:Alimemazine, an antipruritic and HA-receptor antagonist, also partially activates H1R and other GPCRs.Formula:C18H22N2SPurity:98%Color and Shape:Crystals SolidMolecular weight:298.45NGB 2904 hydrochloride
CAS:dopamine D3 receptor antagonistFormula:C28H30Cl3N3OPurity:98%Color and Shape:SolidMolecular weight:530.92Aminopotentidine
CAS:H2 antagonistFormula:C26H35N7O2Purity:98%Color and Shape:SolidMolecular weight:477.6TC-C 14G
CAS:CB1 receptor inverse agonistFormula:C24H17Cl2F2NO4Purity:98%Color and Shape:SolidMolecular weight:492.3RS 64459-193
CAS:<p>RS 64459-193 has a high affinity for the 5-HT1A binding site.</p>Formula:C26H36Cl2N2O2Color and Shape:SolidMolecular weight:479.48Alosetron ((Z)-2-butenedioate)
CAS:<p>Alosetron (GR 68755) (Z)-2-butenedioate is a Serotonin 5HT3-receptor antagonist that is used in the treatment of irritable bowel syndrome.</p>Formula:C21H22N4O5Purity:98%Color and Shape:SolidMolecular weight:410.42LEI-101
CAS:LEI-101: potent CB2 agonist, pEC50=8, bioavailable, >100x selective over CB1, potential for inflammatory diseases.Formula:C23H25FN4O4SPurity:98%Color and Shape:SolidMolecular weight:472.53GSK-894490A
CAS:GSK-894490A is an agonist of ghrelin receptor. GSK-894490A crosses the blood/brain barrier and elicit pro-cognitive effects.Formula:C24H30ClN3O4SColor and Shape:SolidMolecular weight:492.03WAY 629 hydrochloride
CAS:5-HT2C agonistFormula:C15H19ClN2Purity:98%Color and Shape:SolidMolecular weight:262.78Undecylenoyl phenylalanine
CAS:<p>Undecylenoyl phenylalanine (Sepiwhite msh QD) is a novel depigmenting agent, which possibly acts as an alpha-melanocyte-stimulating hormone antagonist, thus</p>Formula:C20H29NO3Purity:≥98%Color and Shape:White To Pinkish Solid PowderMolecular weight:331.45VUF 8430 dihydrobromide
CAS:histamine H4 receptor full agonistFormula:C4H12BrN5SPurity:98%Color and Shape:SolidMolecular weight:242.14Zolantidine dimaleate
CAS:H2 receptor antagonistFormula:C26H31N3O5SPurity:98%Color and Shape:SolidMolecular weight:497.61Antiplatelet agent 2
CAS:<p>Antiplatelet agent 2 is a ticagrelor analogue that exhibits anti-platelet effects and can be used in platelet agglutination studies.</p>Formula:C21H24F2N6O4SColor and Shape:SolidMolecular weight:494.51SB269652
CAS:SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor.Formula:C27H30N4OPurity:98%Color and Shape:SolidMolecular weight:426.55Repinotan HCl
CAS:<p>Repinotan HCl (Bay-x-3702) is a 5-HT1A receptor agonist with potent neuroprotective effects for the study of ischemic stroke and traumatic brain injury.</p>Formula:C21H25ClN2O4SPurity:99.57%Color and Shape:SolidMolecular weight:436.95Indatraline hydrochloride
CAS:Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET)Formula:C16H16Cl3NPurity:98%Color and Shape:SolidMolecular weight:328.66ABT-239
CAS:ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.Formula:C22H22N2OPurity:99.94%Color and Shape:SolidMolecular weight:330.42Cirazoline hydrochloride
CAS:<p>Cirazoline hydrochloride is a synthetic competitive full agonist of α1A-AR (Ki 120 nM) and partial agonist at α1B-AR and α1D-AR.</p>Formula:C13H17ClN2OPurity:99.863%Color and Shape:SolidMolecular weight:252.74GB83
CAS:GB83 is a selective human protease activated receptor 2 (PAR2) antagonist.Formula:C32H44N4O4Purity:98%Color and Shape:SolidMolecular weight:548.72BAY-27-9955
CAS:<p>BAY-27-9955 is a glucagon receptor antagonist.</p>Formula:C23H31FOColor and Shape:SolidMolecular weight:342.49Alclofenac lysinate
CAS:Alclofenac is an anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also used as an analgesic and an antipyretic.Formula:C17H25ClN2O5Purity:98%Color and Shape:SolidMolecular weight:372.84CCK-B Receptor Antagonist 1
CAS:<p>CCK-B Receptor Antagonist 1 is a cholecystokinin B (CCK-B) receptor agonist and has the potential of reducing the secretion of gastric acid.</p>Formula:C28H30N6O3Purity:98%Color and Shape:SolidMolecular weight:498.58Bucumarol (HCl)
CAS:Bucumarol is a beta-adrenergic blocking agent.Formula:C17H24ClNO4Color and Shape:SolidMolecular weight:341.83MHP 133
CAS:<p>MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).</p>Formula:C17H20ClN5O3Purity:98%Color and Shape:SolidMolecular weight:377.83SB-226552
CAS:<p>SB-226552 is an aryloxypropanolamine selective beta3AR agonist.</p>Formula:C25H36NO5PColor and Shape:SolidMolecular weight:461.53BIIL-260 hydrochloride
CAS:BIIL-260 hydrochloride is an LTB4 antagonist with anti-inflammatory activity, inhibiting LTB(4)-induced intracellular Ca(2+) release in human neutrophils.Formula:C30H31ClN2O3Purity:98.89%Color and Shape:SolidMolecular weight:503.03LY 125180
CAS:LY 125180 is a serotonin antagonist.Formula:C18H24ClNOPurity:98%Color and Shape:SolidMolecular weight:305.84(R)-Viloxazine Hydrochloride
CAS:<p>(R)-Viloxazine Hydrochloride, the R-isomer of Viloxazine.</p>Formula:C13H20ClNO3Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:273.76Ro 363
CAS:<p>RO 363: Potent β1-adrenoceptor agonist, boosts heart contractility, lowers diastolic pressure.</p>Formula:C19H25NO6Purity:98%Color and Shape:SolidMolecular weight:363.4A 987306
CAS:<p>A-987306: Potent, oral histamine H4 antagonist; Ki: 3.4 nM (rat), 5.8 nM (human); reduces inflammation in mouse peritonitis.</p>Formula:C18H25N5OColor and Shape:SolidMolecular weight:327.42A1AR antagonist 3
CAS:<p>Compound 13: selective A1AR antagonist, Ki human A1: 9.69 nM, rat A1: 0.529 nM, useful for neurological research.</p>Formula:C25H20N2O3SColor and Shape:SolidMolecular weight:428.5MS47134
<p>MS47134: potent MRGPRX4 agonist, EC50 = 149 nM, for pain/itch/hypersensitivity research.</p>Formula:C22H29NO3Color and Shape:SolidMolecular weight:355.47RWJ 52353
CAS:<p>α2D adrenergic receptor agonist</p>Formula:C11H10N2SPurity:98%Color and Shape:SolidMolecular weight:202.28L-749372
CAS:L-749372 is the beta 3 adrenergic receptor 3-Pyridyloxypropanolamine agonist.Formula:C22H24IN3O4SPurity:98%Color and Shape:SolidMolecular weight:553.41L 641953
CAS:L 641953 is an antagonist of the thromboxane receptor.Formula:C15H9FO3SColor and Shape:SolidMolecular weight:288.29Pancopride
CAS:Pancopride(LAS 30451) is a novel, orally available, long-acting, selective 5-HT3 receptor antagonist that blocks nitrogen mustard and dacarbazine-inducedFormula:C18H24ClN3O2Purity:93.64%Color and Shape:SolidMolecular weight:349.86AF40431
CAS:AF40431 is the first reported small-molecule ligand of sortilin (IC50: 4.4 μM; Kd: 0.7 μM). AF40431 is bound in the neurotensin-binding site of sortilin.Formula:C17H21NO5Color and Shape:SolidMolecular weight:319.35Iloperidone hydrochloride
CAS:Iloperidone hydrochloride is a D(2)/5-HT(2) receptor antagonist. It is also an atypical antipsychotic for the treatment of schizophrenia symptoms.Formula:C24H28ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:462.95ASP1126
CAS:ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist (EC50s: 7.12 nM, 517 nM for hS1P1 and hS1P3).Formula:C26H26ClF6NO5Purity:98%Color and Shape:SolidMolecular weight:581.932-CMDO
CAS:2-CMDO is a Dopamine D2-like receptor antagonist.Formula:C23H23ClN2O5Purity:98%Color and Shape:SolidMolecular weight:442.89A1AR antagonist 5
CAS:<p>A1AR antagonist 5 (compound 20) is a potent and selective antagonist of A1 adenosine receptor (A1AR) with a pKi of 6.11 and a pIC 50 of 5.83 [1].</p>Formula:C17H15ClN4OColor and Shape:SolidMolecular weight:326.78Piclozotan
CAS:Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral artery occlusion (t-MCAO)Formula:C23H24ClN3O2Purity:98.59%Color and Shape:SolidMolecular weight:409.91MRS1097
CAS:MRS1097 is a selective antagonist A3 adenosine receptor.Formula:C26H27NO4Purity:98%Color and Shape:SolidMolecular weight:417.5CBK289001
CAS:<p>CBK289001 inhibits TRAP 5b MV, 5b OX & 5a OX with IC50s: 125μM, 4.21μM, 14.2μM.</p>Formula:C19H20N6O4Color and Shape:SolidMolecular weight:396.4AS604872
CAS:AS604872: Selective FP receptor antagonist, expedites cerebral/aorta degeneration, aids vascular disease models, inhibits uterine contraction.Formula:C28H25N3O3S2Color and Shape:SolidMolecular weight:515.65RP101988
RP101988, a potent Ozanimod metabolite, selectively targets S1PR1 with EC50 of 0.19 nM and S1PR5 at 32.8 nM.Formula:C23H22N4O4Color and Shape:SolidMolecular weight:418.45SB 258719 hydrochloride
CAS:Selective 5-HT7 receptor antagonistFormula:C18H31ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:374.97Fulimetibant
CAS:<p>Fulimetibant is a bradykinin receptor antagonist.</p>Formula:C25H21F4N3O3Color and Shape:SolidMolecular weight:487.45Pirolate
CAS:<p>Pirolate is a receptor of histamine H1.</p>Formula:C16H15N3O5Purity:98%Color and Shape:SolidMolecular weight:329.31UNC9995
CAS:UNC9995 is a β-Arrestin-Biased Dopamine D2 Receptor agonist (β-Arrestin, EC50 = 120 nM; Emax = 88%).Formula:C20H21Cl2N3OSPurity:98%Color and Shape:SolidMolecular weight:422.37Belaperidone
CAS:Belaperidone, an antipsychotic, resembles clozapine, binds D(4) and 5-HT(2A) receptors, minimally extends Q-T without causing arrhythmias.Formula:C22H22FN3O2Color and Shape:SolidMolecular weight:379.43L-692585
CAS:ghrelin receptor (GHS-R1a) agonistFormula:C32H37N7O3Purity:98%Color and Shape:SolidMolecular weight:567.68Argtide
CAS:Argtide is an luteinizing hormone releasing hormone (LHRH) antagonist.Formula:C80H104ClN21O14Color and Shape:SolidMolecular weight:1619.27Bepotastine tosylate
CAS:Bepotastine tosylate: Oral 2nd-gen H1 antagonist, inhibits histamine effects on NGF; treats conjunctivitis, urticaria.Formula:C28H33ClN2O6SColor and Shape:SolidMolecular weight:561.09CVT-2759
CAS:CVT-2759, potential A(1)-ADOR partial agonist, could slow ventricular rate without severe cardiac side effects.Formula:C17H24N6O6Color and Shape:SolidMolecular weight:408.41Ono 1301
CAS:Ono 1301 mimics prostaglandin I2, inhibits thromboxane A2 synthase, reduces pancreatic fibrosis, and boosts cAMP via IP receptor.Formula:C26H24N2O4Color and Shape:SolidMolecular weight:428.48TBC3711
CAS:TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.Formula:C20H21N3O5S2Purity:98%Color and Shape:SolidMolecular weight:447.53VUF-10497
CAS:VUF-10497: H4 receptor inverse agonist, anti-inflammatory in rats, binds human H1 receptor (pKi=7.57).Formula:C18H20ClN5SPurity:98%Color and Shape:SolidMolecular weight:373.9Ticalopride
CAS:Ticalopride: 5-HT3 agonist for digestive, orofacial, ENT disorders, and bulimia, GERD, IBS research.Formula:C14H20ClN3O3Purity:99.51%Color and Shape:SolidMolecular weight:313.78Neldazosin
CAS:<p>Neldazosin is used as a potent α1-adrenoceptor antagonist.</p>Formula:C18H25N5O4Purity:99.74% - 99.76%Color and Shape:SolidMolecular weight:375.42Quinupramine
CAS:Quinupramine: an oral antidepressant targeting the serotonin system; penetrates CNS; doesn’t affect β-adrenergic system.Formula:C21H24N2Purity:99.77%Color and Shape:SolidMolecular weight:304.43SLF1081851
CAS:<p>SLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM.</p>Formula:C21H33N3OPurity:99.26%Color and Shape:SolidMolecular weight:343.51BMY-14802 hydrochloride
CAS:BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects.Formula:C18H23ClF2N4OPurity:99.97%Color and Shape:SolidMolecular weight:384.85Dabelotine
CAS:<p>Dabelotine (UNII-6RY56RB98P) is an adrenergic agonist used in the study of dementia.</p>Formula:C15H22N2O2Purity:98.55%Color and Shape:SolidMolecular weight:262.35CP 96021
CAS:<p>"CP 96021 is an antagonist of 5-HT1/2 receptors, with anti-inflammatory and anti-ulcer effects for treating GI tract and asthma."</p>Formula:C29H21FN4OSPurity:97.81% - 99.62%Color and Shape:SoildMolecular weight:492.57LY 272015 hydrochloride
CAS:LY 272015 hydrochloride is a 5-HT2B receptor antagonist.Formula:C21H25ClN2O2Purity:99.47%Color and Shape:SolidMolecular weight:372.89JZP-361
CAS:JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.Formula:C22H20ClN5OPurity:99.82%Color and Shape:SolidMolecular weight:405.88MM 77 dihydrochloride
CAS:<p>MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.</p>Formula:C19H29Cl2N3O3Purity:99.91%Color and Shape:SolidMolecular weight:418.36
