GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 18 more subcategories

Found 5378 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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Latanoprost lactone diol
CAS:
- 145667-75-0
Latanoprost lactone diol, a key intermediate for synthesizing Latanoprost (a prostaglandin F2α analogue), lowers IOP by activating FP receptors.
Formula:C₁₈H₂₄O₄
Purity:98%
Color and Shape:White Or Almost White Crystalline Powder
Molecular weight:304.38
Ref: TM-T11821
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1,8-Cineole
CAS:
- 470-82-6
Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.
Formula:C₁₀H₁₈O
Purity:97.44% - 97.44%
Color and Shape:Solid
Molecular weight:154.25
Ref: TM-T1714
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15-keto-17-phenyl trinor Prostaglandin F2α
CAS:
- 949564-89-0
Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.
Formula:C₂₃H₃₀O₅
Color and Shape:Solid
Molecular weight:386.488
Ref: TM-T37934
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PACAP (6-38), human, ovine, rat TFA
PACAP (6-38) is a PACAP receptor blocker with IC50s of 30, 600, 40 nM for type I, VIP1, and VIP2 receptors.
Formula:C₁₈₄H₃₀₁N₅₆FO₄₇S
Purity:98%
Color and Shape:Solid
Molecular weight:4138.76
Ref: TM-TP1438
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Amitraz
CAS:
- 33089-61-1
Amitraz (NSC 324552): white monoclinic crystals, mp 86-87°C, water-insoluble, used as acaricide and in canine demodectic mange.
Formula:C₁₉H₂₃N₃
Purity:99.88%
Color and Shape:White/Pale Yellow Crystalline Solid
Molecular weight:293.41
Ref: TM-T1632
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JNJ-39933673
CAS:
- 1404307-42-1
JNJ-39933673 is a bio-active chemical.
Formula:C₄₈H₅₄F₂N₂O₁₁
Color and Shape:Solid
Molecular weight:872.96
Ref: TM-T32305
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Glucagon receptor antagonists-1
CAS:
- 503559-84-0
Glucagon receptor antagonist -1 is a highly effective glucagon receptor antagonist.
Formula:C₂₉H₃₄FNO₂
Purity:98%
Color and Shape:Solid
Molecular weight:447.58
Ref: TM-T11413
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Parstatin(human) TFA
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, effectively inhibits angiogenesis, as indicated by studies [1] [2].
Formula:C₁₉₃H₃₃₁F₃N₆₄O₅₅S₃
Color and Shape:Solid
Molecular weight:4581.28
Ref: TM-T75873
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AdTx1
Selective non-competitive α1A adrenoceptor antagonist with Ki of 0.35 nM; inactive on other GPCRs; affects phenylephrine actions.
Formula:C₃₁₀H₄₈₁N₈₇O₁₀₀S₈
Purity:98%
Color and Shape:Solid
Molecular weight:7283.22
Ref: TM-TP2086
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Taspoglutide
CAS:
- 275371-94-3
Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes
Formula:C₁₅₂H₂₃₂N₄₀O₄₅
Purity:98%
Color and Shape:Solid
Molecular weight:3339.763
Ref: TM-T13091
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GRL018-21
GRL018-21 is a potent, highly selective inhibitor of G protein-coupled receptor kinase 5 (GRK5), exhibiting an IC50 of 10 nM [1].
Color and Shape:Odour Solid
Ref: TM-T82258
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Misoprostol acid
CAS:
- 112137-89-0
Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers.
Formula:C₂₁H₃₆O₅
Purity:98%
Color and Shape:Solid
Molecular weight:368.51
Ref: TM-T12047
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Adenosine 2',5'-diphosphate sodium
CAS:
- 154146-84-6
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist with non-selective antagonism at recombinant and human platelet P2X1 receptors.
Formula:C₁₀H₁₅N₅NaO₁₀P₂
Color and Shape:Solid
Molecular weight:450.192
Ref: TM-T39025
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[Ala11,D-Leu15]-Orexin B(human)
CAS:
- 532932-99-3
OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).
Formula:C₁₂₀H₂₀₆N₄₄O₃₅S
Purity:98%
Color and Shape:Solid
Molecular weight:2857.28
Ref: TM-TP1975
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Mosapride citrate dihydrate
CAS:
- 636582-62-2
Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.
Formula:C₂₇H₃₅ClFN₃O₁₁
Purity:98%
Color and Shape:Solid
Molecular weight:632.04
Ref: TM-T6597L
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Substance P (alligator)
CAS:
- 113516-47-5
Substance P from alligator: a neuropeptide with structure Arg-Pro-Arg-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2.
Formula:C₆₃H₉₈N₂₀O₁₃S
Color and Shape:Solid
Molecular weight:1375.64
Ref: TM-T76449
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Neurokinin B
CAS:
- 86933-75-7
NKB, a tachykinin peptide, impacts human functions like gonadotropin-releasing hormone secretion.
Formula:C₅₅H₇₉N₁₃O₁₄S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1210.42
Ref: TM-TP1363
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GLP-1R agonist 4
CAS:
- 2401894-26-4
GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.
Formula:C₃₂H₃₀ClF₂N₃O₅
Color and Shape:Solid
Molecular weight:610.05
Ref: TM-T74323
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Y1 receptor antagonist 1 formic
H 409-22 isomer formic, a formate salt of Y1 receptor antagonist 1, is an antagonist of the neuropeptide Y1 receptor (neuropeptide Y1 receptor). This compound effectively blocks the actions of the receptor, playing a crucial role in modulating physiological responses.
Formula:C₂₉H₃₅N₅O₅
Color and Shape:Solid
Molecular weight:533.62
Ref: TM-T200259
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Veldoreotide
CAS:
- 252845-37-7
Veldoreotide (Somatoprim): a somatostatin analogue targeting receptors 2, 4, 5, reduces GH in pituitary adenomas.
Formula:C₆₀H₇₄N₁₂O₁₀
Purity:98%
Color and Shape:Solid
Molecular weight:1123.3
Ref: TM-TP2420
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LAS190792
CAS:
- 1347232-69-2
LAS190792 (AZD8999) is a dual muscarinic antagonist/β2-agonist, pIC50s (M1-M5, β1-β3): 8.9-5.6; used as a bronchodilator.
Formula:C₃₉H₄₃ClN₄O₉S₂
Color and Shape:Solid
Molecular weight:811.36
Ref: TM-T74709
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cAC 253 acetate
cAC 253 acetate (TP2135 Free base) is an amylin antagonist. cAC 253 acetate inhibits 125I-adrenomedullin binding, with an IC50 of 25 nM.
Formula:C₁₂₈H₂₀₆N₄₂O₄₂S₂
Purity:98.16% - 99.99%
Color and Shape:Soild
Molecular weight:3069.39
Ref: TM-TP2135L
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BMS-753426
CAS:
- 1004536-52-0
BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .
Formula:C₂₅H₃₃F₃N₆O₂
Color and Shape:Solid
Molecular weight:506.574
Ref: TM-T38397
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LSN3160440
CAS:
- 2765539-59-9
LSN3160440 is a GLP-1R allosteric modulator and PPI stabilizer aiding inactive GLP-1 attachment.
Formula:C₂₇H₂₇Cl₂N₃O
Color and Shape:Solid
Molecular weight:480.43
Ref: TM-T75112
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AB21 HCl
AB21 HCl: σ1 receptor antagonist, Ki 13 nM; less potent at σ2 (102 nM). Reduces mechanical hypersensitivity.
Formula:C₂₃H₂₉ClN₂O
Purity:99.91%
Color and Shape:Solid
Molecular weight:384.2
Ref: TM-T77340L
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SB-408124
CAS:
- 288150-92-5
SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.
Formula:C₁₉H₁₈F₂N₄O
Purity:99.81%
Color and Shape:Solid
Molecular weight:356.37
Ref: TM-T6658
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Melanostatin, frog TFA
Melanostatin, frog TFA is an α-MSH release inhibitor, a 36 amino acid peptide isolated from the frog brain.
Purity:99.23%
Color and Shape:Odour Solid
Ref: TM-TP2603L
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LY 344864 racemate
CAS:
- 186543-64-6
LY 344864 racemate is a 5-HT1F receptor agonist.
Formula:C₂₁H₂₂FN₃O
Purity:99.75%
Color and Shape:Soild
Molecular weight:351.42
Ref: TM-T2344L
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CH 275
CAS:
- 174688-78-9
Potent sst1 agonist with 30.9 nM IC50; selective over sst2-5; inhibits somatostatin in rat nucleus accumbens.
Formula:C₇₄H₉₆N₁₄O₁₅S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1485.8
Ref: TM-TP2045
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Substance P(1-7) TFA
CAS:
- 2828433-22-1
Substance P(1-7) TFA is a fragment of neuropeptide P (SP), with anti-harmful effects, used in neurological disease research.
Formula:C₄₃H₆₆F₃N₁₃O₁₂
Purity:98.23%
Color and Shape:Solid
Molecular weight:1014.06
Ref: TM-T75963
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Septide
CAS:
- 79775-19-2
Septide is an NK1 receptor agonist acting at a site distinct from substance P.
Formula:C₃₉H₅₃N₇O₇S
Purity:98%
Color and Shape:Solid
Molecular weight:763.95
Ref: TM-TP2352
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HS014
CAS:
- 207678-81-7
Potent MC4 antagonist; Ki: 3.16 nM (MC4), 108 (MC1), 54.4 (MC3), 694 (MC5). Boosts rat appetite, mouse pain, blocks IL-1β Fos in hypothalamus.
Formula:C₇₁H₉₄N₂₀O₁₇S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1563.77
Ref: TM-TP2015
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9-deoxy-9-methylene Prostaglandin E2
CAS:
- 61263-32-9
9-deoxy-9-methylene PGE2: stable PGE2 analog with similar effects, less side effects, equal potency in rats, gerbils, primates.
Formula:C₂₁H₃₄O₄
Color and Shape:Solid
Molecular weight:350.499
Ref: TM-T36728
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[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide
CAS:
- 313988-89-5
Potent, selective NPY Y5 receptor agonist; IC50: 0.24 nM (Y5), >500 nM (Y2), 530 nM (Y1), 51 nM (Y4); Ki: 0.1-0.15 nM (Y5); increases food intake in vivo.
Formula:C₁₈₃H₂₈₁N₅₇O₅₄S₂
Purity:98%
Color and Shape:Solid
Molecular weight:4207.67
Ref: TM-TP1963
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TRAP-5 amide
CAS:
- 141923-41-3
TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1].
Formula:C₃₀H₅₁N₉O₆
Color and Shape:Solid
Molecular weight:633.78
Ref: TM-T80111
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PACAP (1-27), human, ovine, rat
CAS:
- 127317-03-7
PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.
Formula:C₁₄₂H₂₂₄N₄₀O₃₉S
Purity:98%
Color and Shape:Solid
Molecular weight:3147.66
Ref: TM-TP1070
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Prostaglandin H1
CAS:
- 52589-22-7
Prostaglandin H1 is the cyclooxygenase metabolite of DGLA, a CRTh2 agonist and a precursor of a family of 1 anti-inflammatory prostaglandins.
Formula:C₂₀H₃₄O₅
Color and Shape:Solid
Molecular weight:354.487
Ref: TM-T37328
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MrgprX2 antagonist-5
CAS:
- 2527815-74-1
MrgprX2 antagonist-5 from patent WO2020223255A1 inhibits MrgprX2, useful for inflammatory skin disorder studies.
Formula:C₁₉H₁₃ClF₂N₄O₂S
Color and Shape:Solid
Molecular weight:434.85
Ref: TM-T40176
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d[Cha4]-AVP
CAS:
- 500170-27-4
Potent human V1B vasopressin receptor agonist; Ki: V1B=1.2 nM; increases ACTH, corticosterone; low vasopressor effect.
Formula:C₅₀H₇₁N₁₃O₁₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1094.31
Ref: TM-TP2082
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Cortistatin 14, human, rat
CAS:
- 193829-96-8
Cortistatin 14: a neuropeptide similar to somatostatin; induces sleep, depresses neuronal activity; found in cortex, hippocampus.
Formula:C₈₁H₁₁₃N₁₉O₁₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1721.01
Ref: TM-TP1188
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Hemokinin 1, human TFA
Hemokinin-1 is a human TFA and selective NK1 agonist; also activates NK2 & NK3 and induces opioid-independent analgesia.
Formula:C₅₆H₈₅F₃N₁₄O₁₆S
Color and Shape:Solid
Molecular weight:1299.42
Ref: TM-T75840
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Scyliorhinin II
CAS:
- 112748-19-3
Scyliorhinin II, a cyclic Tachykinin peptide, is a potent NK3 receptor agonist.
Formula:C₇₇H₁₁₉N₂₁O₂₆S₃
Purity:98%
Color and Shape:Solid
Molecular weight:1851.09
Ref: TM-TP1851
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Antisauvagine-30
CAS:
- 220673-95-0
CRF2 receptor antagonist; Kd 1.4 nM (mCRF2β), 153.6 nM (rCRF1). Blocks sauvagine-induced cAMP in cells & stress-related responses in mice.
Formula:C₁₆₁H₂₇₄N₄₈O₄₆S
Purity:98%
Color and Shape:Solid
Molecular weight:3650.29
Ref: TM-TP2091
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ACT-1016-0707
CAS:
- 2569467-78-1
ACT-1016-0707 is a selective, insurmountable LPA1 antagonist with antifibrotic and anti-inflammatory activity in lung fibrosis models
Formula:C₁₉H₂₃ClN₄O₄S
Purity:99.905%
Color and Shape:Solid
Molecular weight:438.93
Ref: TM-T85589
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[Ala1,3,11,15]-Endothelin
CAS:
- 121204-87-3
Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
Formula:C₁₀₉H₁₆₃N₂₅O₃₂S
Purity:98%
Color and Shape:Solid
Molecular weight:2368
Ref: TM-TP2099
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VU0453379
CAS:
- 1638646-27-1
VU0453379 is a highly selective and central nervous system penetrant positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).
Formula:C₂₆H₃₄N₄O₂
Purity:98%
Color and Shape:Solid
Molecular weight:434.57
Ref: TM-T17242
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HAEGTFTSD
CAS:
- 926018-45-3
HAEGTFTSD is GLP-1's initial segment; GLP-1 (7-36) amide, tied to food intake, stems from preproglucagon in L-cells.
Formula:C₄₀H₅₇N₁₁O₁₇
Purity:98%
Color and Shape:Solid
Molecular weight:963.94
Ref: TM-TP1452
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Neuropeptide Y (18-36) (porcine)
CAS:
- 114495-97-5
"Neuropeptide Y (18-36) (porcine) is a NPY heart receptor blocker, halts I-NPY binding, aids in heart failure research."
Formula:C₁₁₂H₁₇₄N₃₆O₂₇
Color and Shape:Solid
Molecular weight:2456.8
Ref: TM-T76357
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pCPA methyl ester hydrochloride
CAS:
- 14173-40-1
pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.
Formula:C₁₀H₁₃Cl₂NO₂
Purity:99.73% - 99.88%
Color and Shape:Solid
Molecular weight:250.12
Ref: TM-T41143
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O-Desmethyl Mebeverine alcohol
CAS:
- 155172-67-1
Mebeverine metabolite O-desmethyl alcohol inhibits α1 receptors, relaxing the gut.
Formula:C₁₅H₂₅NO₂
Purity:98%
Color and Shape:Solid
Molecular weight:251.36
Ref: TM-T11989
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GLP-1(7-36), amide acetate
CAS:
- 1119517-19-9
GLP-1(7-36), amide acetate is a derivative of GLP-1 peptide , activate the GLP-1 receptor, promote insulin secretion,Type 2 diabetes mellitus and obesity.
Formula:C₁₅₁H₂₃₀N₄₀O₄₇
Purity:99.89%
Color and Shape:Solid
Molecular weight:3357.68
Ref: TM-TP1141
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Linaclotide acetate
CAS:
- 851199-60-5
Linaclotide acetate, an oral guanylate cyclase C agonist with 14 amino acids, treats constipation-predominant IBS and chronic constipation.
Formula:C₆₁H₈₃N₁₅O₂₃S₆
Purity:98%
Color and Shape:Solid
Molecular weight:1586.79
Ref: TM-T11852L
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Dipentylone hydrochloride
CAS:
- 17763-13-2
Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.
Formula:C₁₄H₂₀ClNO₃
Purity:99.94%
Color and Shape:Solid
Molecular weight:285.77
Ref: TM-T205977
+ Info
σ1 Receptor ligand 1
σ1 Receptor ligand 1 (compound 5I) is a σ1 receptor ligand with a Ki value of 3.9 nM. It demonstrates a high plasma protein binding rate (89%) and exhibits good metabolic stability in the presence of mouse liver microsomes and NADPH. σ1 Receptor ligand 1 is applicable in neuroscience and cancer research.
Formula:C₂₂H₂₈N₂O₂
Color and Shape:Solid
Molecular weight:352.47
Ref: TM-T201225
+ Info
LY-53857 free base
CAS:
- 32896-53-0
LY-53857 free base is a bioactive chemical.
Formula:C₂₃H₃₂N₂O₃
Color and Shape:Solid
Molecular weight:384.51
Ref: TM-T33018
+ Info
Thielavin A
CAS:
- 71950-66-8
Thielavin A, from T. terricola, inhibits COX and glucose-6-phosphatase; non-competitive α-glucosidase inhibitor.
Formula:C₂₉H₃₀O₁₀
Color and Shape:Solid
Molecular weight:538.549
Ref: TM-T37774
+ Info
Quetiapine-d4 fumarate
CAS:
- 1287376-15-1
Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.
Formula:C₂₅H₂₉N₃O₆S
Purity:98%
Color and Shape:Solid
Molecular weight:503.61
Ref: TM-T12618
+ Info
S1PR1 modulator 1
CAS:
- 2328109-05-1
S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
Formula:C₂₃H₂₄N₂O₃S
Purity:99.69%
Color and Shape:Solid
Molecular weight:408.51
Ref: TM-T12821
+ Info
β2AR/M-receptor agonist-1
CAS:
- 2230520-62-2
β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and
Formula:C₄₃H₅₆BrN₃O₇
Color and Shape:Solid
Molecular weight:806.82
Ref: TM-T74708
+ Info
Human growth hormone-releasing factor TFA
Human growth hormone-releasing factor TFA is a hypothalamic peptide that promotes GH secretion by targeting pituitary GHRHR.
Formula:C₂₁₇H₃₅₉F₃N₇₂O₆₈S
Color and Shape:Solid
Molecular weight:5153.67
Ref: TM-T75713
+ Info
Benzquinamide
CAS:
- 63-12-7
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer
Formula:C₂₂H₃₂N₂O₅
Purity:94.86%
Color and Shape:Solid
Molecular weight:404.5
Ref: TM-T12343
+ Info
Kisspeptin-10, human
CAS:
- 374675-21-5
Kisspeptin-10, human is an effective vasoconstrictor and inhibitor of angiogenesis.
Formula:C₆₃H₈₃N₁₇O₁₄
Purity:98%
Color and Shape:Solid
Molecular weight:1302.462
Ref: TM-TP1396
+ Info
GLP-1 moiety from Dulaglutide
GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist.
Formula:C₁₄₉H₂₂₁N₃₇O₄₉
Purity:98%
Color and Shape:Solid
Molecular weight:3314.62
Ref: TM-TP1316
+ Info
CCZ01048 TFA
CCZ01048 TFA, α-MSH analog, binds MC1R with 0.31 nM affinity, internalizes in melanoma cells, and is stable for melanoma PET imaging.
Formula:C₇₃H₁₀₆F₃N₂₁O₁₈
Color and Shape:Solid
Molecular weight:1622.75
Ref: TM-T76072L
+ Info
Tetrahydro-β-carboline
CAS:
- 16502-01-5
Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
Formula:C₁₁H₁₂N₂
Purity:96.31%
Color and Shape:Tan Solid
Molecular weight:172.2264
Ref: TM-Fr12161
+ Info
Secretin, porcine
CAS:
- 17034-34-3
Porcine secretin: 27-amino acid peptide for diagnosing pancreatic dysfunction and gastrinoma, stimulates bicarbonate fluid.
Formula:C₁₃₀H₂₂₀N₄₄O₄₁·xC₂H₄O₂
Purity:98%
Color and Shape:Solid
Molecular weight:N/A
Ref: TM-TP1048
+ Info
tetranor-PGJM
CAS:
- 1352751-83-7
Tetranor-PGJM is a metabolite of prostaglandin D2 and is associated with the anti-inflammatory effects of curcumin.
Formula:C₁₆H₂₂O₆
Color and Shape:Solid
Molecular weight:310.346
Ref: TM-T38307
+ Info
Propranolol hydrochloride
CAS:
- 318-98-9
Propranolol hydrochloride is a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse
Formula:C₁₆H₂₂ClNO₂
Purity:99.94% - >99.99%
Color and Shape:White Or Almost White Powder White Powder
Molecular weight:295.80
Ref: TM-T0812
+ Info
Leukotriene B4 Ethanolamide
CAS:
- 877459-63-7
LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.
Formula:C₂₂H₃₇NO₄
Color and Shape:Solid
Molecular weight:379.541
Ref: TM-T37619
+ Info
PF-9184
CAS:
- 1221971-47-6
PF-9184 inhibits human mPGES-1 selectively, with an IC50 of 16.5 nM, and reduces IL-1β-stimulated PGE2 production in vitro.
Formula:C₂₁H₁₄Cl₂N₂O₄S
Purity:97.43%
Color and Shape:Solid
Molecular weight:461.32
Ref: TM-T21738
+ Info
Substance P(1-7)
CAS:
- 68060-49-1
Substance P(1-7) is a bioactive metabolite of tachykinin SP with anti-inflammatory and analgesic properties.
Formula:C₄₁H₆₅N₁₃O₁₀
Purity:98%
Color and Shape:Solid
Molecular weight:900.04
Ref: TM-T7396
+ Info
Neuropeptide S(Mouse)
CAS:
- 412938-74-0
Endogenous NPSR agonist, EC50 = 3 nM. Boosts Ca2+ levels, activity, wakefulness, reduces anxiety in mice.
Formula:C₉₃H₁₅₆N₃₄O₂₇
Purity:98%
Color and Shape:Solid
Molecular weight:2182.47
Ref: TM-TP1981
+ Info
Glucagon-like peptide 1 (1-37), human
CAS:
- 87805-34-3
Human GLP-1 (1-37) is a potent GLP-1 receptor agonist without impact on rat food intake or insulin secretion.
Formula:C₁₈₆H₂₇₅N₅₁O₅₉
Purity:98%
Color and Shape:Solid
Molecular weight:4169.48
Ref: TM-TP1148
+ Info
Cholecystokinin (27-32)-amide
CAS:
- 86367-90-0
Cholecystokinin (27-32)-amide is a CCK receptor antagonist.
Formula:C₃₆H₄₈N₈O₁₂S₃
Purity:98%
Color and Shape:Solid
Molecular weight:881.01
Ref: TM-T23886
+ Info
QWF
CAS:
- 126088-82-2
Tripeptide SP antagonist (IC50: 90 μM); blocks SP-MRGPR X2 binding and mast cell degranulation; reduces 48/80-induced scratching in mice.
Formula:C₃₈H₄₃N₅O₈
Purity:98%
Color and Shape:Solid
Molecular weight:697.78
Ref: TM-TP1946
+ Info
JKC363
CAS:
- 436083-30-6
MC4 receptor antagonist; IC50: 0.5 nM (MC4), 44.9 nM (MC3). Blocks α-MSH, reduces TRH, food intake, and pain.
Formula:C₆₉H₉₁N₁₉O₁₆S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1506.72
Ref: TM-TP2011
+ Info
Tecastemizole
CAS:
- 75970-99-9
Tecastemizole (R 43512) is a selective antagonist of H1 receptor and a major metabolite of astemizole with anti-inflammatory effects.
Formula:C₁₉H₂₁FN₄
Purity:99.70%
Color and Shape:Solid
Molecular weight:324.4
Ref: TM-T26253
+ Info
(±)5(6)-EET
CAS:
- 87173-80-6
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.
Formula:C₂₀H₃₂O₃
Color and Shape:Solid
Molecular weight:320.473
Ref: TM-T36070
+ Info
Sarafotoxin S6a
CAS:
- 126738-34-9
Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.
Formula:C₁₀₅H₁₅₆N₂₈O₃₄S₅
Purity:98%
Color and Shape:Solid
Molecular weight:2514.85
Ref: TM-TP2119
+ Info
HCGRP-(8-37)
CAS:
- 119911-68-1
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist
Formula:C₁₃₉H₂₃₀N₄₄O₃₈
Purity:98%
Color and Shape:Solid
Molecular weight:3125.59
Ref: TM-TP1134
+ Info
G-Protein antagonist peptide
CAS:
- 143675-79-0
Peptide inhibits G protein-receptor binding; competitively blocks M2 and β-adrenoceptor-induced Gs/Gi/Go activation.
Formula:C₅₇H₆₄N₁₂O₉S
Purity:98%
Color and Shape:Solid
Molecular weight:1093.27
Ref: TM-TP1902
+ Info
Relamorelin TFA
CAS:
- 2863659-22-5
Relamorelin (RM-131) TFA: ghrelin analog, GHSR agonist, 0.42 nM affinity, boosts growth hormone, enhances gastric emptying, potential in motility disorders.
Formula:C₄₅H₅₁F₃N₈O₇S
Color and Shape:Solid
Molecular weight:905
Ref: TM-T75262
+ Info
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
CAS:
- 211190-38-4
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype
Formula:C₄₂H₆₃FN₁₂O₈
Color and Shape:Solid
Molecular weight:883.02
Ref: TM-T80240
+ Info
PAR650097
PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.
Purity:96.67% (SEC-HPLC) - 98.83% (SEC-HPLC)
Color and Shape:Liquid
Molecular weight:145.5kDa
Ref: TM-T77402
+ Info
Zoliprofen
CAS:
- 56355-17-0
Zoliprofen: potent, oral NSAID with anti-inflammatory, antipyretic, analgesic effects. Exceeds ibuprofen's efficacy in rats and rabbits.
Formula:C₁₂H₁₁NO₃S
Purity:99.62%
Color and Shape:Solid
Molecular weight:249.29
Ref: TM-T68025
+ Info
Proglumide hemicalcium
CAS:
- 85068-56-0
Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.
Formula:C₁₈H₂₈CaN₂O₄
Purity:98%
Color and Shape:Solid
Molecular weight:376.51
Ref: TM-T12544
+ Info
Sphinganine 1-phosphate
CAS:
- 19794-97-9
Sphinganine 1-phosphate has protects kidney and liver through activation of the S1P1 receptor in mice and acts as an agonist for S1P4 in Homo sapien.
Formula:C₁₈H₄₀NO₅P
Color and Shape:Solid
Molecular weight:381.49
Ref: TM-T39401
+ Info
B7-33
CAS:
- 1818415-56-3
B7-33 is a single-chain relaxin analog and a selective agonist for relaxin receptor 1 (RXFP1). It binds to RXFP1 and preferentially activates the pERK pathway in cells expressing RXFP1, rather than cAMP. B7-33 serves as an antifibrotic agent and provides cardioprotective effects.
Formula:C₁₃₁H₂₂₉N₄₁O₃₆S
Color and Shape:Solid
Molecular weight:2986.54
Ref: TM-TP2903
+ Info
Cetirizine D8 dihydrochloride
CAS:
- 2070015-04-0
Cetirizine D8 dihydrochloride is a deuterated H1-antihistamine with long-acting effects.
Formula:C₂₁H₂₆Cl₂N₂O₃
Purity:98%
Color and Shape:Solid
Molecular weight:433.4
Ref: TM-T19234
+ Info
Atrial Natriuretic Peptide (ANP) (1-28), rat
CAS:
- 88898-17-3
Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
Formula:C₁₂₈H₂₀₅N₄₅O₃₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3062.41
Ref: TM-TP1221
+ Info
Calcitonin (8-32), salmon
CAS:
- 155069-90-2
Calcitonin (8-32), salmon: selective amylin receptor antagonist, regulates calcium/phosphorus, thyroid origin, 32-aa peptide.
Formula:C₁₁₉H₁₉₈N₃₆O₃₇
Purity:98%
Color and Shape:Solid
Molecular weight:2725.06
Ref: TM-TP1677
+ Info
CYM5442 hydrochloride
CAS:
- 1783987-80-3
CYM 5442 HCl: potent, selective S1P1 agonist (EC50 = 1.35 nM), induces MAPK activation & lymphopenia, brain-penetrant.
Formula:C₂₃H₂₈ClN₃O₄
Color and Shape:Solid
Molecular weight:445.94
Ref: TM-T41144
+ Info
Anthramycin
CAS:
- 4803-27-4
Anthramycin: a PBD family antibiotic with antitumor effects and CNS cholecystokinin antagonist properties in mice.
Formula:C₁₆H₁₇N₃O₄
Color and Shape:Solid
Molecular weight:315.32
Ref: TM-T74863
+ Info
Prostaglandin F2α 1,11-lactone
CAS:
- 62410-84-8
Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma.
Formula:C₂₀H₃₂O₄
Purity:98%
Color and Shape:Solid
Molecular weight:336.47
Ref: TM-T37326
+ Info
CB1R antagonist 2
CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.
Formula:C₂₄H₂₆N₄O
Color and Shape:Solid
Molecular weight:386.49
Ref: TM-T205110
+ Info
19(R)-hydroxy Prostaglandin E1
CAS:
- 64625-55-4
19(R)-hydroxy Prostaglandin E1 is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle and is the major prostaglandin
Formula:C₂₀H₃₄O₆
Color and Shape:Solid
Molecular weight:370.486
Ref: TM-T37778
+ Info
(+)-Cloprostenol sodium
CAS:
- 62561-03-9
Cloprostenol sodium is a water-soluble PGF2α analog and FP receptor agonist, promoting luteolysis in rats and hamsters.
Formula:C₂₂H₂₈ClNaO₆
Color and Shape:Solid
Molecular weight:446.9
Ref: TM-T29245
+ Info
Amylin (1-37), human acetate
Amylin (1-37), human acetate, a peptide hormone containing 37 amino acids secreted by the pancreas in conjunction with insulin, inhibits glucagon secretion.
Purity:96.21%
Color and Shape:Odour Solid
Ref: TM-T76480L
+ Info
Sibenadet hydrochloride
CAS:
- 154189-24-9
Sibenadet, a D2/beta2-agonist, is potential useful for the treatment of symptoms of chronic obstructive pulmonary disease.
Formula:C₂₂H₂₉ClN₂O₅S₂
Color and Shape:Solid
Molecular weight:501.06
Ref: TM-T28774
+ Info
d[Cha4]-AVP TFA
d[Cha4]-AVP TFA: potent, selective V1b agonist, K i 1.2 nM, favors V1b over V1a, V2, oxytocin receptors.
Formula:C₅₂H₇₂F₃N₁₃O₁₃S₂
Color and Shape:Solid
Molecular weight:1208.33
Ref: TM-T75933
+ Info
M40
CAS:
- 143896-17-7
Potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat
Formula:C₉₄H₁₄₅N₂₃O₂₄
Purity:98%
Color and Shape:Solid
Molecular weight:1981.33
Ref: TM-TP1992
+ Info
MrgprX2 antagonist-2
CAS:
- 2642346-30-1
MrgprX2 antagonist-2, from patent WO2021092262A1 E163, is potent for skin inflammation studies.
Formula:C₁₇H₁₆F₅N₃O₃
Color and Shape:Solid
Molecular weight:405.325
Ref: TM-T40273
+ Info
5-HT5AR/5-HT6R ligand-1
5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.
Formula:C₂₅H₃₀N₄O₂S
Color and Shape:Solid
Molecular weight:450.6
Ref: TM-T205096
+ Info
ACTH (1-14)
CAS:
- 25696-21-3
ACTH (1-14) is a pituitary hormone fragment that controls cortisol and androgen levels.
Formula:C₇₇H₁₀₉N₂₁O₂₀S
Purity:98%
Color and Shape:Solid
Molecular weight:1680.88
Ref: TM-TP1238
+ Info
Beraprost
CAS:
- 88430-50-6
Beraprost is a stable prostacyclin analog.
Formula:C₂₄H₃₀O₅
Color and Shape:Solid
Molecular weight:398.49
Ref: TM-T30426
+ Info
PG-931 TFA
PG-931 TFA, a potent MC4 receptor agonist (IC50 0.58 nM), excels in selectivity and helps reverse hemorrhagic shock in vivo.
Formula:C₆₁H₈₆F₃N₁₅O₁₃
Color and Shape:Solid
Molecular weight:1294.42
Ref: TM-T75847
+ Info
D[LEU4,LYS8]-VP TFA
D[LEU4,LYS8]-VP TFA: V1b receptor agonist; K_i: 0.16 nM (rat), 0.52 nM (human), 1.38 nM (mouse); weak antidiuretic/vasopressor/oxytocic.
Formula:C₄₉H₆₈F₃N₁₁O₁₃S₂
Color and Shape:Solid
Molecular weight:1140.25
Ref: TM-T75826
+ Info
γ-2-MSH (41-58), amide
CAS:
- 799841-81-9
Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor.
Formula:C₇₄H₁₀₀N₂₂O₁₅S
Purity:98%
Color and Shape:Solid
Molecular weight:1569.79
Ref: TM-TP1532
+ Info
Ornipressin
CAS:
- 3397-23-7
Ornipressin is a vasoconstrictor, haemostatic and renal agent.
Formula:C₄₅H₆₃N₁₃O₁₂S₂
Purity:98%
Color and Shape:White Powder
Molecular weight:1042.19
Ref: TM-TP1049
+ Info
AC-263093
CAS:
- 849459-86-5
AC-263093 is an NPFFR2 agonist with anxiolytic activity that increases c-Fos protein expression in the paraventricular nucleus of the hypothalamus.
Formula:C₈H₈Br₂N₄
Purity:99.78%
Color and Shape:Soild
Molecular weight:319.98
Ref: TM-T83651
+ Info
BE-24566B
CAS:
- 149466-04-6
BE-24566B, a polyketide from S. violaceusniger, inhibits various bacteria and blocks ET receptors (ETA IC50=11 μM, ETB=3.9 μM).
Formula:C₂₇H₂₄O₇
Color and Shape:Solid
Molecular weight:460.482
Ref: TM-T38167
+ Info
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
CAS:
- 150646-45-0
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a corticotropin-releasing factor (CRF) antagonist known to counteract the inhibitory effects of IL-1a
Formula:C₁₅₉H₂₆₇N₄₉O₄₃
Color and Shape:Solid
Molecular weight:3553.12
Ref: TM-T76602
+ Info
Amylin (IAPP), feline TFA
Amylin (IAPP), feline TFA: 37-amino acid peptide; inhibits insulin/glucagon; secreted by pancreatic β-cells.
Formula:C₁₆₇H₂₇₁F₃N₅₂O₅₆S₂
Color and Shape:Solid
Molecular weight:4024.47
Ref: TM-T76028
+ Info
BMS-196085
CAS:
- 170686-10-9
BMS-196085 is an effective and selective human β( 3) All agonists of adrenergic receptors, in β( 1) Partial agonist activity was 45%.
Formula:C₂₄H₂₆F₂N₂O₅S
Color and Shape:Solid
Molecular weight:492.54
Ref: TM-T30504
+ Info
rGHRH(1-29)NH2
RGHRH (1-29)NH2 is a synthetic peptide that stimulates the secretion of growth hormone (GH).
Formula:C₁₅₅H₂₅₁N₄₉O₄₀S
Purity:98%
Color and Shape:Solid
Molecular weight:3473.02
Ref: TM-TP1393
+ Info
Alsactide
CAS:
- 34765-96-3
Alsactide, an adrenocorticotropic hormone (ACTH) agonist and a heptadecapeptide analogue, is utilized in the study of the central nervous system [1].
Formula:C₉₉H₁₅₅N₂₉O₂₁S
Color and Shape:Solid
Molecular weight:2119.53
Ref: TM-T76297
+ Info
CRF(6-33)(human)
CAS:
- 120066-38-8
CRFBP inhibitor peptide; blocks CRF, reduces weight gain, boosts activity in obese rats.
Formula:C₁₄₁H₂₃₁N₄₁O₄₃S
Purity:98%
Color and Shape:Solid
Molecular weight:3220.68
Ref: TM-TP2047
+ Info
Apelin-36(rat, mouse)
CAS:
- 230299-95-3
Endogenous APJ agonist from adipocytes; binds APJ tightly, inhibits cAMP, regulates heart function and fluid balance, blocks some HIV strains.
Formula:C₁₈₅H₃₀₄N₆₈O₄₃S
Purity:98%
Color and Shape:Solid
Molecular weight:4200.93
Ref: TM-TP2094
+ Info
Ilatreotide
CAS:
- 119719-11-8
Ilatreotide is a Amadori compound of octreotide.
Formula:C₆₁H₈₆N₁₀O₂₀S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1343.53
Ref: TM-TP2387
+ Info
tBPC
CAS:
- 1942-71-8
Enhances Y4R response to PP, NPY & PYY with EC50 of 0.03, 0.4, 0.5 nM; selective for Y4R over Y1R, Y2R, Y5R.
Formula:C₁₆H₂₄O₂
Color and Shape:Solid
Molecular weight:248.36
Ref: TM-T37528
+ Info
4-P-PDOT
CAS:
- 134865-74-0
4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
Formula:C₁₉H₂₁NO
Purity:99.91%
Color and Shape:Solid
Molecular weight:279.38
Ref: TM-T14042
+ Info
TT-OAD2 free base
CAS:
- 1246826-07-2
TT-OAD2 free base, a non-peptide GLP-1 receptor agonist, can treat diabetes; has an EC50 of 5 nM.
Formula:C₅₀H₄₇Cl₂N₃O₆
Purity:98%
Color and Shape:Solid
Molecular weight:856.83
Ref: TM-T11406
+ Info
Kisspeptin-10, human TFA
"Kisspeptin-10, human TFA: vasoconstrictor, angiogenesis inhibitor, metastasis suppressor via GPR54, key in kidney development & osteoblast differentiation."
Formula:C₆₃H₈₃N₁₇O₁₄·C₂HF₃O₂
Color and Shape:Solid
Molecular weight:1416.46
Ref: TM-T75745
+ Info
Meluadrine tartrate
CAS:
- 134865-37-5
Meluadrine tartrate is an endogenous metabolite.
Formula:C₁₆H₂₄ClNO₈
Purity:98%
Color and Shape:Solid
Molecular weight:393.82
Ref: TM-T11999
+ Info
Crustacean Cardioactive Peptide (CCAP)
CAS:
- 309247-84-5
Crustacean Cardioactive Peptide (CCAP) is a conserved modified cyclic nonapeptide primary structure of PFCNAFTGC-NH2, a disulfide bridge between Cys3 and Cys9.
Formula:C₄₂H₅₈N₁₀O₁₂S₂
Purity:95.40%
Color and Shape:Solid
Molecular weight:959.1
Ref: TM-TP1413
+ Info
Parstatin(human)
CAS:
- 1065755-99-8
Cell-permeable PAR1-derived peptide; inhibits endothelial migration, proliferation (IC50 ~3μM), induces apoptosis, and has cardioprotective effects.
Formula:C₁₉₁H₃₃₀N₆₄O₅₃S₃
Purity:98%
Color and Shape:Solid
Molecular weight:4467.29
Ref: TM-TP1965
+ Info
RFRP-1(human)
CAS:
- 311309-25-8
Endogenous NPFF agonist with EC50 of 0.0011 nM (NPFF2) and 29 nM (NPFF1); reduces cardiac function and raises prolactin in rats. GnIH homolog.
Formula:C₆₇H₁₀₁N₁₉O₁₄S
Purity:98%
Color and Shape:Solid
Molecular weight:1428.72
Ref: TM-TP1937
+ Info
SR-140603
CAS:
- 154728-59-3
SR-140603, the less potent enantiomer of SR 140333, is used as the negative control.
Formula:C₃₇H₄₅Cl₃N₂O₂
Purity:98%
Color and Shape:Solid
Molecular weight:656.12
Ref: TM-T26222
+ Info
Bradykinin (1-3)
CAS:
- 23815-91-0
Bradykinin (1-3) is a fragment of Bradykinin. Bradykinin is an activates pain receptors.
Formula:C₁₆H₂₈N₆O₄
Purity:98%
Color and Shape:Solid
Molecular weight:368.43
Ref: TM-TP1780
+ Info
(R,R)-Palonosetron Hydrochloride
CAS:
- 135729-75-8
(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron
Formula:C₁₉H₂₅ClN₂O
Purity:98%
Color and Shape:Solid
Molecular weight:332.87
Ref: TM-T13437
+ Info
OXA(17-33)
CAS:
- 343268-91-7
Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.
Formula:C₇₉H₁₂₅N₂₃O₂₂
Purity:98%
Color and Shape:Solid
Molecular weight:1749
Ref: TM-TP1973
+ Info
Methionyl-Lysyl-Bradykinin
CAS:
- 550-19-6
Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin analogue, is a kinin [1] [2] .
Formula:C₆₁H₉₄N₁₈O₁₃S
Color and Shape:Solid
Molecular weight:1319.58
Ref: TM-T76384
+ Info
Peptide YY (PYY), human
CAS:
- 118997-30-1
PYY: a 36-amino-acid hormone, amidated, part of neuroendocrine control, acts via Neuropeptide Y receptors.
Formula:C₁₉₄H₂₉₅N₅₅O₅₇
Purity:98%
Color and Shape:Solid
Molecular weight:4309.75
Ref: TM-TP1762
+ Info
Angiopeptin TFA
CAS:
- 2478421-60-0
Angiopeptin TFA: somatostatin analogue, sst2/sst5 partial agonist (IC50: 0.26/6.92 nM), suppresses GH & IGF-1, for atherosclerosis research.
Formula:C₅₈H₇₃F₆N₁₁O₁₄S₂
Color and Shape:Solid
Molecular weight:1326.39
Ref: TM-T76042
+ Info
M617
CAS:
- 860790-38-1
Galanin GAL1 agonist, Ki: GAL1 0.23 nM, GAL2 5.71 nM; boosts rat appetite, lessens inflammation pain.
Formula:C₁₁₂H₁₆₁N₂₉O₂₈
Purity:98%
Color and Shape:Solid
Molecular weight:2361.68
Ref: TM-TP1993
+ Info
Dexchlorpheniramine free base
CAS:
- 25523-97-1
Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.
Formula:C₁₆H₁₉ClN₂
Purity:98%
Color and Shape:Oily Liquid Solid
Molecular weight:274.79
Ref: TM-T0785L
+ Info
α-CGRP(human)
CAS:
- 90954-53-3
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.
Formula:C₁₆₃H₂₆₇N₅₁O₄₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3789.33
Ref: TM-TP2044
+ Info
GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.
Formula:C₃₀H₃₃FN₂O₄
Color and Shape:Solid
Molecular weight:504.59
Ref: TM-T201190
+ Info
(Ala13)-Apelin-13 TFA
'(Ala13)-Apelin-13 TFA acts as a potent antagonist of the apelin receptors (APJ) and impedes gastric motility via the vagal cholinergic pathway [1].'
Formula:C₆₃H₁₀₇N₂₃O₁₆S·xC₂HF₃O₂
Color and Shape:Solid
Molecular weight:1474.73 (free acid)
Ref: TM-T78109
+ Info
Adrenomedullin (16-31), human TFA
Human adrenomedullin (16-31) TFA, fragment 16-31, binds CGRP1 receptor, raises rat blood pressure, not cats’.
Formula:C₈₄H₁₃₀F₃N₂₅O₂₃S₂
Color and Shape:Solid
Molecular weight:1979.21
Ref: TM-T76011
+ Info
Sphingosine-1-phosphate (d16:1)
CAS:
- 709026-60-8
C16 S1P binds S1P1/EDG-1 (115%), S1P3/EDG-3 (83%), S1P2/EDG-5 (103%) receptors; elevated in glaucoma.
Formula:C₁₆H₃₄NO₅P
Color and Shape:Solid
Molecular weight:351.424
Ref: TM-T37955
+ Info
Dehydro Aripiprazole (hydrochloride)
CAS:
- 1008531-60-9
Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.
Formula:C₂₃H₂₆Cl₃N₃O₂
Color and Shape:Solid
Molecular weight:482.83
Ref: TM-T36664
+ Info
Naratriptan D3 Hydrochloride
CAS:
- 1190021-64-7
Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.
Formula:C₁₇H₂₆ClN₃O₂S
Purity:98%
Color and Shape:Solid
Molecular weight:374.94
Ref: TM-T12176
+ Info
TGR5 agonist 1
Compound 18 (TGR5 agonist 1) is a potent agonist of TGR5, exhibiting an EC50 value of 0.31 µM [1].
Formula:C₂₈H₄₈NNaO₆S
Color and Shape:Solid
Molecular weight:549.74
Ref: TM-T74824
+ Info
17-phenoxy trinor Prostaglandin F2α ethyl amide
CAS:
- 1421369-12-1
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
Formula:C₂₅H₃₇NO₅
Color and Shape:Solid
Molecular weight:431.573
Ref: TM-T37938
+ Info
Orexin B, rat, mouse TFA
Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.
Formula:C₁₂₈H₂₁₆F₃N₄₅O₃₆S
Color and Shape:Solid
Molecular weight:3050.42
Ref: TM-T75925
+ Info
Sulamserod
CAS:
- 219757-90-1
Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related
Formula:C₁₉H₂₈ClN₃O₅S
Purity:98.76%
Color and Shape:Solid
Molecular weight:445.96
Ref: TM-T13021
+ Info
Lys-[Hyp3]-Bradykinin
CAS:
- 113662-39-8
Lys-[Hyp3]-Bradykinin, a human urine-derived kinin and bradykinin agonist, is used for inflammation research.
Formula:C₅₆H₈₅N₁₇O₁₃
Color and Shape:Solid
Molecular weight:1204.38
Ref: TM-T76293
+ Info
Neurokinin B (TFA)
CAS:
- 101536-55-4
Neurokinin B TFA, a tachykinin, targets NK1R, NK2R, nk3r GPCRs, modulating effects.
Formula:C₅₉H₈₁F₆N₁₃O₁₈S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1438.47
Ref: TM-TP1279
+ Info
Kisspeptin-10, rat
CAS:
- 478507-53-8
Kisspeptin-10, rat is an Endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54).
Formula:C₆₃H₈₃N₁₇O₁₅
Purity:98%
Color and Shape:Solid
Molecular weight:1318.44
Ref: TM-TP1666
+ Info
PF-4348235 HCl
PF-4348235 HCl (β2AR/M-receptor agonist-2 HCl) is a muscarinic M3 receptor antagonist (Ki: 0.73 nM) and β2 adrenergic receptor agonist (MABA, EC50: 3.7 nM). PF-4348235 HCl is also a bronchial BM213 acetate is a bronchodilator used to study cardiovascular and respiratory diseases such as chronic obstructive pulmonary disease (COPD).
Formula:C₃₆H₅₀Cl₂N₄O₇S
Purity:98.81%
Color and Shape:Solid
Molecular weight:753.78
Ref: TM-T72226L
+ Info
OXA(17-33) TFA
OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).
Formula:C₈₁H₁₂₆F₃N₂₃O₂₄
Color and Shape:Solid
Molecular weight:1863
Ref: TM-T75922
+ Info
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
CAS:
- 124199-90-2
(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].
Formula:C₄₉H₆₉N₁₃O₉
Color and Shape:Solid
Molecular weight:984.15
Ref: TM-T76601
+ Info
Flunarizine
CAS:
- 52468-60-7
Flunarizine is an orally administered peripheral vasodilator, a dual blocker of voltage-gated Na+/Ca2+ channels and a D2 dopamine receptor antagonist.
Formula:C₂₆H₂₆F₂N₂
Purity:99.9%
Color and Shape:Solid
Molecular weight:404.50
Ref: TM-T21392
+ Info
Calcitonin Gene Related Peptide (CGRP) II, rat
CAS:
- 99889-63-1
CGRP II is a potent vasodilator that boosts pancreatic enzyme levels by activating β-cell receptors.
Formula:C₁₆₃H₂₆₇N₅₁O₅₀S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3805.31
Ref: TM-TP1202
+ Info
INCB3344 R-isomer
INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.
Formula:C₂₉H₃₄F₃N₃O₆
Purity:98%
Color and Shape:Solid
Molecular weight:577.59
Ref: TM-T11650
+ Info
Cortistatin-8
CAS:
- 485803-62-1
ghrelin receptor antagonist
Formula:C₄₇H₆₈N₁₂O₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1009.25
Ref: TM-TP2236
+ Info
AL 34662
CAS:
- 210580-75-9
AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a
Formula:C₁₀H₁₃N₃O
Purity:99.77%
Color and Shape:Solid
Molecular weight:191.23
Ref: TM-T22029
+ Info
IRL-1620 acetate
IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.
Formula:C₈₈H₁₂₁N₁₇O₂₉
Purity:96.64%
Color and Shape:Solid
Molecular weight:1881
Ref: TM-T15595L
+ Info
Angiopeptin
CAS:
- 113294-82-9
Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.
Formula:C₅₄H₇₁N₁₁O₁₀S₂
Color and Shape:Solid
Molecular weight:1098.34
Ref: TM-T25087
+ Info
MCUF-651
CAS:
- 2747162-85-0
MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 μM.
Formula:C₁₇H₂₂F₂N₄OS
Purity:99.83%
Color and Shape:Soild
Molecular weight:368.44
Ref: TM-T67734
+ Info
[Des-Arg10]-HOE I40 TFA
[Des-Arg10]-HOE I40 TFA is a potent antagonist of the bradykinin B1 receptor.
Formula:C₅₃H₇₇N₁₅O₁₂S·xC₂HF₃O₂
Color and Shape:Solid
Ref: TM-T207446
+ Info
[Lys4] Sarafotoxin S6c
CAS:
- 1219444-22-0
[Lys4] Sarafotoxin S6c: potent partial endothelin receptor agonist; causes pig coronary contraction, EC50=1.5 nM.
Formula:C₁₀₅H₁₅₃N₂₇O₃₆S₅
Color and Shape:Solid
Molecular weight:2529.82
Ref: TM-T76302
+ Info
CKLF1-C27 TFA
CKLF1-C27 peptide activates ERK1/2 via CCR4, competes with CKLF1, promotes HUVEC growth, and has psoriasis research potential.
Formula:C₁₅₃H₂₄₄F₃N₃₉O₃₉
Color and Shape:Solid
Molecular weight:3310.8
Ref: TM-T76245L
+ Info
V-0219 hydrochloride
V-0219 hydrochloride: oral GLP-1R PAM for obesity-linked diabetes study.
Formula:C₂₀H₂₆ClF₃N₄O₂
Purity:99.97%
Color and Shape:Soild
Molecular weight:446.89
Ref: TM-T60047L
+ Info
(D-Ala2)-GRF (1-29) amide (human)
CAS:
- 89453-59-8
(D-Ala2)-GRF (1-29) amide (human) is a potent superagonist of Growth Hormone-Releasing Factor (GRF), demonstrating an exceptionally high Growth Hormone (GH)-
Formula:C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular weight:3357.88
Ref: TM-T83549
+ Info
LTB4-IN-2
LTB4-IN-2 (Compound 6x) is a selective inhibitor of Leukotriene B4 (LTB4), acting by specifically targeting the 5-Lipoxygenase-activating protein (FLAP) with an
Formula:C₂₄H₁₇N₅S₂
Purity:98%
Color and Shape:Solid
Molecular weight:439.56
Ref: TM-T79389
+ Info
Adrenomedullin (11-50), rat
CAS:
- 163648-32-6
Adrenomedullin 11-50 rat is a peptide, stimulates CGRP1 receptor for vasodilation, used in bone growth research.
Formula:C₁₉₄H₃₀₄N₅₈O₅₉S₄
Purity:98%
Color and Shape:Solid
Molecular weight:4521.17
Ref: TM-TP1625
+ Info
Nemifitide diTFA
CAS:
- 204992-09-6
Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.
Formula:C₃₇H₄₅F₇N₁₀O₁₀
Purity:99.78% - 99.84%
Color and Shape:Solid
Molecular weight:922.8
Ref: TM-TP1127
+ Info
N-Desmethyl Pimavanserin
CAS:
- 639863-77-7
N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.
Formula:C₂₄H₃₂FN₃O₂
Purity:98.02%
Color and Shape:Solid
Molecular weight:413.53
Ref: TM-T37979
+ Info
(D-Trp6)-LHRH free acid
CAS:
- 129418-54-8
(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone ( LHRH ) agonist [1] .
Formula:C₆₄H₈₁N₁₇O₁₄
Molecular weight:1312.43
Ref: TM-T76617
+ Info
ZL-1101
ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.
Color and Shape:Odour Liquid
Ref: TM-T9901A-1091
+ Info
20-Carboxy-Leukotriene B4
CAS:
- 80434-82-8
20-COOH LTB4, a metabolite of LTB4, binds BLT1 receptor and inhibits LTB4-induced neutrophil responses.
Formula:C₂₀H₃₀O₆
Color and Shape:Solid
Molecular weight:366.45
Ref: TM-T73793
+ Info
Satoreotide
CAS:
- 1801415-23-5
Satoreotide (JR11) is an SSTR2 antagonist, typically conjugated with radiolabeled chelators for use in neuroendocrine tumor imaging [1].
Formula:C₅₈H₇₂ClN₁₅O₁₄S₂
Color and Shape:Solid
Molecular weight:1302.87
Ref: TM-TP2620
+ Info
Benzomalvin B
CAS:
- 157047-97-7
Benzomalvin B, a metabolite from Penicillium, blocks 24% NK1 receptor binding at 100 μg/ml.
Formula:C₂₄H₁₇N₃O₂
Color and Shape:Solid
Molecular weight:379.419
Ref: TM-T38033
+ Info
GHRF, bovine
CAS:
- 88894-91-1
bGRF(1-44)-NH2 is a bovine GH-releasing factor that stimulates GH release and synergizes with Hydrocortisone.
Formula:C₂₂₀H₃₆₆N₇₂O₆₆S
Color and Shape:Solid
Molecular weight:5104.72
Ref: TM-T76325
+ Info
[D-Trp8,Tyr11] Somatostatin
CAS:
- 75176-06-6
[D-Trp8,Tyr11] Somatostatin, an analogue of the hormone somatostatin that modulates numerous bodily functions, is characterized by the substitution of DTrp8,
Formula:C₇₆H₁₀₄N₁₈O₂₀S₂
Molecular weight:1653.88
Ref: TM-T83494
+ Info
DOTA-EB-TATE
DOTA-EB-TATE is formed by combining the SST peptide derivative DOTA-octreotate with an Evans blue analog (EB). This peptide drug conjugate (PDC) enhances the pharmacokinetics of SSTR2 analogs and reduces PRRT toxicity. Additionally, DOTA-EB-TATE serves in the synthesis/research of radiopharmaceutical conjugates (RDC).
Formula:C₁₀₅H₁₃₃N₂₁O₃₀S₅
Molecular weight:2329.63
Ref: TM-TP2996
+ Info
Urotensin I
CAS:
- 83930-33-0
Urotensin I, 41-aa neuropeptide, agonist for human/rat CRF receptors, lowers blood pressure in rats, isolated from white suckers.
Formula:C₂₁₀H₃₄₀N₆₂O₆₇S₂
Purity:98%
Color and Shape:Solid
Molecular weight:4869.46
Ref: TM-TP1199
+ Info
ACTH (34-39)
CAS:
- 69454-10-0
ACTH (34-39) is an adrenocorticotropic hormone fragment.
Formula:C₃₇H₅₀N₆O₉
Purity:98%
Color and Shape:Solid
Molecular weight:722.83
Ref: TM-TP1751
+ Info
[Tyr0] Corticotropin Releasing Factor, ovine
CAS:
- 83930-34-1
[Tyr^0] Corticotropin Releasing Factor, ovine, is a hypothalamic hormone sourced from sheep that prompts the secretion of adrenocorticotropic hormone (ACTH) and
Ref: TM-T83484
+ Info
Levitide
CAS:
- 114281-19-5
Levitide is a neurohormone-like peptide which is from the skin of Xenopus laevis.
Formula:C₆₆H₁₁₉N₂₁O₁₉S
Purity:98%
Color and Shape:Solid
Molecular weight:1542.85
Ref: TM-T20704
+ Info
Dapiglutide
CAS:
- 2296814-85-0
Dapiglutide (ZP7570) is a long-acting GLP-1R & GLP-2R dual agonist for SBS research.
Color and Shape:Solid
Ref: TM-T39820
+ Info
Lanepitant
CAS:
- 170566-84-4
Lanepitant (LY303870) is a non-peptide neurokinin-1 (NK-1) antagonist with analgesic activity for the prevention of migraine.
Formula:C₃₃H₄₅N₅O₃
Purity:97.71%
Color and Shape:Solid
Molecular weight:559.74
Ref: TM-T25615
+ Info
Sorbinicate
CAS:
- 6184-06-1
Sorbinicate is an antihypercholesterolaemic and vasodilating nicotinic acid ester.
Formula:C₄₂H₃₂N₆O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:812.74
Ref: TM-T26201
+ Info
CTP-amiodarone
CTP-amiodarone, a cellular-penetrating conjugate of myocardial cell-targeting peptide and Amiodarone, exhibits anti-arrhythmic activity by blocking Na+, K+, and Ca2+ channels as well as β-adrenergic receptors.
Formula:C₉₇H₁₃₁F₃I₂N₂₀O₂₅S₂
Color and Shape:Solid
Molecular weight:2352.13
Ref: TM-TP2921
+ Info
Brain Natriuretic Peptide-45, rat
CAS:
- 123337-89-3
BNP-45 (rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency.
Formula:C₂₁₃H₃₄₉N₇₁O₆₅S₃
Purity:98%
Color and Shape:Solid
Molecular weight:5040.67
Ref: TM-TP1207
+ Info
BA 1 TFA
BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.
Formula:C₅₉H₇₇F₃N₁₄O₁₃
Color and Shape:Solid
Molecular weight:1247.32
Ref: TM-T75945
+ Info
FR167344 free base
CAS:
- 215258-13-2
FR167344 free base: oral, nonpeptide B2 bradykinin receptor antagonist, high-affinity (IC50: 65 nM), no B1 affinity.
Formula:C₃₀H₂₈BrCl₂N₅O₄
Purity:98%
Color and Shape:Solid
Molecular weight:673.38
Ref: TM-T15347
+ Info
Mirtazapine N-oxide
CAS:
- 155172-12-6
Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.
Formula:C₁₇H₁₉N₃O
Color and Shape:Solid
Molecular weight:281.359
Ref: TM-T37430
+ Info
[Tyr11]-Somatostatin
CAS:
- 59481-27-5
[Tyr11]-Somatostatin, a neuroactive peptide, aids proteomics research and modulates retinal function.
Formula:C₇₆H₁₀₄N₁₈O₂₀S₂
Molecular weight:1653.89
Ref: TM-T40680
+ Info
MM 54
CAS:
- 1313027-43-8
Potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM), counters [Pyr1]-Apelin-13, inhibits glioblastoma growth in mice.
Formula:C₇₀H₁₂₁N₂₉O₁₅S₄
Purity:98%
Color and Shape:Solid
Molecular weight:1737.15
Ref: TM-TP2001
+ Info
Dexbrompheniramine maleate
CAS:
- 2391-03-9
Dexbrompheniramine is an antihistamine used for hay fever and urticaria, blocking H1 receptors in the body.
Formula:C₂₀H₂₃BrN₂O₄
Color and Shape:Solid
Molecular weight:435.318
Ref: TM-T31396
+ Info
26Rfa, Hypothalamic Peptide, human
CAS:
- 600171-68-4
26RFa, a human neuropeptide, stimulates appetite and possibly regulates feeding and the gonadotropic axis, with ≈80% identity across human, rat, and frog.
Formula:C₁₂₇H₁₉₅N₃₇O₃₇
Purity:98%
Color and Shape:Solid
Molecular weight:2832.13
Ref: TM-TP1542
+ Info
Xylamidine
CAS:
- 6443-50-1
Xylamidine is a biochemical.
Formula:C₁₉H₂₄N₂O₂
Color and Shape:Solid
Molecular weight:312.41
Ref: TM-T35195
+ Info
GR 82334
CAS:
- 129623-01-4
Tachykinin NK1 receptor antagonist.
Formula:C₆₉H₉₁N₁₅O₁₆
Purity:98%
Color and Shape:Solid
Molecular weight:1386.57
Ref: TM-TP2024
+ Info
RF9
CAS:
- 876310-60-0
RF9 is an effective and selective antagonist of the Neuropeptide FF receptor (Kis: 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively).
Formula:C₂₆H₃₈N₆O₃
Purity:98%
Color and Shape:Solid
Molecular weight:482.62
Ref: TM-T16738
+ Info
IRL-1038
CAS:
- 144602-02-8
ETB endothelin receptor antagonist
Formula:C₆₈H₉₂N₁₄O₁₅S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1409.67
Ref: TM-TP2262
+ Info
α-MSH acetate
α-MSH acetate is an endogenous neuromodulatory peptide derived from POMC and an agonist of MC4R (melanocortin receptor 4).
Purity:99.71%
Color and Shape:Odour Solid
Ref: TM-T7813L
+ Info
Physalaemin
CAS:
- 2507-24-6
Physalaemin is a non-mammalian tachykinin.
Formula:C₅₈H₈₄N₁₄O₁₆S
Purity:98%
Color and Shape:Solid
Molecular weight:1265.45
Ref: TM-T19518