GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(2,994 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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SUN B8155
CAS:SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.Formula:C14H15N3O3Purity:99.38% - 99.38%Color and Shape:SolidMolecular weight:273.29Allura Red AC (Standard)
CAS:Allura Red AC (Standard) is the standard substance of Allura Red AC, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Allura Red AC (CI 16035) is a very important food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries.Allura Red AC promotes susceptibility to experimental colitis via mouse intestinal serotonin.Formula:C18H14N2Na2O8S2Color and Shape:Dark Maroon Solid PowderMolecular weight:496.42Emedastine Difumarate
CAS:Emedastine Difumarate, an H1 receptor blocker for allergic conjunctivitis, reduces histamine-induced eye inflammation.Formula:C25H34N4O9Color and Shape:SolidMolecular weight:534.56Bromperidol hydrochloride
CAS:Bromperidol hydrochloride is a D2 dopamine receptor antipsychotic; enhances Spectinomycin's mycobactericidal effects.Formula:C21H24BrClFNO2Color and Shape:SolidMolecular weight:456.78Gizzerosine
CAS:Gizzerosine, a biogenic amine formed during feed processing, is a toxicant that induces mortality in livestock.Formula:C11H20N4O2Color and Shape:SolidMolecular weight:240.3Fexofenadine-d6
CAS:Fexofenadine D6 is an antihistamine pharmaceutical drug.Fexofenadine D6 is deuterium labeled is Fexofenadine.Formula:C32H39NO4Purity:98%Color and Shape:SolidMolecular weight:507.694,4-Diphenylbutylamine hydrochloride
CAS:4,4-Diphenylbutylamine shows affinity for the 5-HT2A and H1 receptors with Kis of 2589 and 1670 nM, respectively[1].Formula:C16H20ClNColor and Shape:SolidMolecular weight:261.79β2AR/M-receptor agonist-2
CAS:β2AR/M-receptor agonist-2 is a dual-function compound acting as a muscarinic antagonist and β2 adrenoceptor agonist (MABA).Formula:C36H49ClN4O7SColor and Shape:SolidMolecular weight:717.311-Phenylbiguanide HCl
CAS:Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.Formula:C8H12ClN5Purity:99.31%Color and Shape:SolidMolecular weight:213.67Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Formula:C23H24N2O2Color and Shape:SolidMolecular weight:360.45Ceralifimod
CAS:Ceralifimod (ONO-4641) is a potent agonist for sphingosine 1-phosphate receptors 1 and 5 (EC50s: 27.3, 334 pM for human S1P receptor 1 and 5).Formula:C27H33NO4Color and Shape:SolidMolecular weight:435.56GLP-1 receptor agonist 2
CAS:GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist.Formula:C30H31ClFN5O4Color and Shape:SolidMolecular weight:580.05MK-761 TFA
MK-761 TFA is an effective, orally active β2-adrenergic receptor blocker. It exhibits antihypertensive properties and positive inotropic effects, along with vasodilatory activity.Formula:C15H20F3N3O4Color and Shape:SolidMolecular weight:363.332Lysosphingomyelin (d18:1)
CAS:Sphingomyelins are phosphorylcholine, sphingosine, and fatty acid. Lysosphingomyelin, missing the fatty acid, activates diverse cellular pathways.Formula:C23H49N2O5PColor and Shape:SolidMolecular weight:464.628Bradykinin (1-5)
CAS:Bradykinin (1-5), a stable metabolite of BK produced by ACE, serves as a marker for in vivo BK generation.Formula:C27H40N8O6Color and Shape:SolidMolecular weight:572.66(S)-ZINC-3573
CAS:(S)-ZINC 3573 is a negative control for (R)-ZINC 3573. (S)-ZINC 3573 displays no activity at MRGPRX2 at concentrations below 100 μM.Formula:C18H21N5Color and Shape:SolidMolecular weight:307.401Endothelin-3 (Rat,Human) (TFA)
Endothelin-3 (Rat, Human) (TFA) is a 21-amino acid vasoactive peptide of endothelial origi, an agonist for the endothelin receptor type B (EDNRB).Formula:C123H169F3N26O35S4·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:2757.07 (free base)Lanreotide
CAS:Lanreotide, a somatostatin analogue, suppresses GH/IGF-I hypersecretion in acromegaly patients. It also used to manage neuroendocrine tumours.Formula:C54H69N11O10S2Color and Shape:SolidMolecular weight:1096.32Timapiprant sodium
CAS:Timapiprant sodium: potent DP2 antagonist; inhibits mast cell activation; displaces [3H]PGD2, Ki=3-13 nM.Formula:C21H17FN2NaO2Purity:98%Color and Shape:SolidMolecular weight:371.367BMS-986020 sodium
CAS:BMS-986020 sodium (AM152 sodium) is a high-affinity LPA1 antagonist for investigating idiopathic pulmonary fibrosis.Formula:C29H25N2NaO5Purity:99.83%Color and Shape:SolidMolecular weight:504.51Altanserin
CAS:Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.Formula:C22H22FN3O2SColor and Shape:SolidMolecular weight:411.49Methyldopate
CAS:Methyldopate, an ethyl ester prodrug of methyldopa, inhibits dopamine decarboxylase to treat hypertension.Formula:C12H17NO4Color and Shape:SolidMolecular weight:239.274-Hydroxypropranolol-d7 hydrochloride
CAS:Deuterium-labeled 4-Hydroxypropranolol HCl, a Propranolol metabolite that blocks β1/β2 receptors.Formula:C16H22ClNO3Purity:98%Color and Shape:SolidMolecular weight:318.85Doxepin D3 Hydrochloride
CAS:Doxepin D3 Hydrochloride is a deuterium-labeled doxepin hydrochloride.Doxepin hydrochloride is an oral active tricyclic antidepressant used as a sedative.Doxepin hydrochloride is also an effective CYP450 inhibitor, significantly inhibiting CYP450 2C19 andFormula:C19H22ClNOPurity:98%Color and Shape:SolidMolecular weight:318.86Substance P TFA
CAS:Substance P TFA is a CNS neuropeptide, serving as a neurotransmitter and modulator, targeting NK1R.Formula:C65H99F3N18O15SPurity:98%Color and Shape:SolidMolecular weight:1461.67Diacetolol D7
CAS:Diacetolol D7 is deuterium-labeled diacetone Roller. Diacetol is the main metabolite of Acetolol. Diacetololβ-adrenoceptor shielding and anti-arrhythmic agent.Formula:C16H24N2O4Purity:98%Color and Shape:SolidMolecular weight:315.42Etofylline clofibrate
CAS:Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.Formula:C19H21ClN4O5Color and Shape:SolidMolecular weight:420.85Diphenylpyraline
CAS:Diphenylpyridine is the first generation antihistamine, which has the anticholinergic effect of diphenylpiperidine.Formula:C19H23NOColor and Shape:SolidMolecular weight:281.39R121919
CAS:R121919 (NBI30775) is an adrenocorticotropin-releasing factor receptor 1 (CRF1) receptor antagonist with antidepressant and anxiolytic activity.Formula:C22H32N6Purity:99.75%Color and Shape:SolidMolecular weight:380.53Zaloglanstat
CAS:Zaloglanstat (ISC-27864) is a selective, orally active mPGES-1 inhibitor with an IC50 of 5 nM, analgesic in osteoarthritis and inflammatory arthritis.Formula:C21H20ClF3N4O2Purity:99.97%Color and Shape:SolidMolecular weight:452.86Ref: TM-T39000
1mg154.00€5mg371.00€10mg620.00€25mg1,305.00€50mg1,765.00€100mg2,367.00€1mL*10mM (DMSO)409.00€Flibanserin-d4
CAS:Flibanserin: Serotonin 5-HT1A agonist (Ki=1 nM), 5-HT2A antagonist (49 nM). Flibanserin D4 is deuterium-labeled.Formula:C20H21F3N4OPurity:98%Color and Shape:SolidMolecular weight:394.43RU-SKI 43 Hydrochloride
CAS:RU-SKI 43 Hydrochloride is a selective Hedgehog acyltransferase inhibitor (IC50 850 nM) with reported anticancer activity in tumor biology studies.Formula:C22H31ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:423.01Dapagliflozin impurity
CAS:Dapagliflozin impurity is the enantiomer of Dapagliflozin, Dapagliflozin is a sodium glucose transporter 2 inhibitor.Formula:C21H25ClO7Color and Shape:SolidMolecular weight:424.875-HT2B antagonist-1
CAS:Orally active 5-HT2B antagonist; IC50 = 33.4 nM; potential for hepatocellular, cardiovascular, GI disease research.Formula:C11H14BrN5Purity:99.965%Color and Shape:SolidMolecular weight:296.17Fenoterol-d6 Hydrobromide
CAS:Fenoterol-d6 Hydrobromide is a deuterated compound of Fenoterol Hydrobromide. Fenoterol Hydrobromide has a CAS number of 1944-12-3. Fenoterol hydrobromide, the hydrobromide salt of fenoterol, is a β2 adrenoreceptor agonist with bronchodilator activity.Formula:C17H16D6BrNO4Molecular weight:390.30Terlipressin
CAS:Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells.Formula:C52H74N16O15S2Purity:98%Color and Shape:SolidMolecular weight:1227.37Fipexide hydrochloride
CAS:Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.Formula:C20H22Cl2N2O4Color and Shape:SolidMolecular weight:425.31Cefaclor
CAS:Cefaclor (Panoral) is a cephalosporin antibiotic.Formula:C15H14ClN3O4SPurity:99.03% - 99.98%Color and Shape:SolidMolecular weight:367.81Antazoline phosphate
CAS:Antazoline phosphate: H1 histamine receptor antagonist with anticholinergic effects, eases allergies.Formula:C17H22N3O4PPurity:98%Color and Shape:CoaMolecular weight:363.35Thioridazine
CAS:Thioridazine: an antipsychotic, anti-anxiety drug, blocks dopamine D2, PI3K-Akt-mTOR; halts angiogenesis, kills cancer cells, targets CSCs.Formula:C21H26N2S2Color and Shape:SolidMolecular weight:370.57NBI-27914
CAS:NBI-27914 is a selective and non-peptide CRFR1 (corticotropin-releasing factor receptor 1) antagonist with analgesic effects, capable of blocking CRF-induced anxiety.Formula:C18H20Cl4N4Purity:99.47% - 99.64%Color and Shape:SolidMolecular weight:434.19SKF-82958 hydrobromide
CAS:SKF-82958 hydrobromide is a D1/D5 receptor full agonist.Formula:C19H21BrClNO2Purity:98%Color and Shape:SolidMolecular weight:410.73Nadolol-d9
CAS:Nadolol D9 is the deuterium labeled Nadolol is a blocker of non-selective beta.
Formula:C17H27NO4Purity:98%Color and Shape:SolidMolecular weight:318.46(R)-Praziquantel-d11
CAS:(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel.Formula:C19H24N2O2Purity:98%Color and Shape:SolidMolecular weight:323.47JNJ-10397049
CAS:OX2 receptor antagonistFormula:C19H20Br2N2O3Color and Shape:SolidMolecular weight:484.18SB-674042
CAS:SB-674042 is a nonpeptide dual antagonist of the appetite peptides OX1 and OX2 receptors.SB-674042 is used in the treatment of depression.Formula:C24H21FN4O2SPurity:99.87% - 99.9%Color and Shape:SolidMolecular weight:448.51Clorprenaline
CAS:Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.Formula:C11H16ClNOPurity:98.9%Color and Shape:SolidMolecular weight:213.7Docosahexaenoic acid ethyl ester
CAS:Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) enhances 6-hydroxydopamine-induced neuronal damage by inducing lipid peroxidation in the mouse striatum, and can be used to study oxidative diseases of the retina or neurons.Formula:C24H36O2Purity:98.35%Color and Shape:SolidMolecular weight:356.54TP-16
CAS:TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
Formula:C24H22FNO4SPurity:98.53% - 99.15%Color and Shape:SolidMolecular weight:439.5Mozavaptan hydrochloride
CAS:Mozavaptan is a vasopressin receptor antagonist.Formula:C27H30ClN3O2Color and Shape:SolidMolecular weight:464
