GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(248 products)
- Adrenergic Receptor(3,031 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(154 products)
- CaSR(34 products)
- Cannabinoid Receptor(216 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(191 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(59 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5963 products of "GPCR/G-Protein"
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KB-5492 anhydrous
CAS:KB 5492 is an agent of anti-ulcer. It preventing cysteamine-induced duodenal ulcers by stimulating duodenal HCO3- secretion.Formula:C27H34N2O10Color and Shape:SolidMolecular weight:546.57Tripelennamine citrate
CAS:Tripelennamine citrate, an ethylenediamine derivative, blocks H1 receptors to treat allergies and anaphylaxis.Formula:C22H29N3O7Color and Shape:SolidMolecular weight:447.488Nuciferine
CAS:Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera.Formula:C19H21NO2Purity:98.76% - 99.79%Color and Shape:SolidMolecular weight:295.38Lys-Bradykinin acetate(342-10-9 free base)
CAS:Lys-Bradykinin acetate is an endogenous bradykinin receptor agonist.Formula:C58H89N17O14Purity:99.86%Color and Shape:SolidMolecular weight:1248.43Flibanserin hydrochloride
CAS:Flibanserin HCl: oral 5-HT1A agonist & 5-HT2A antagonist, Ki values 1 nM & 49 nM, for HSDD, has antidepressant/anxiolytic properties.Formula:C20H22ClF3N4OColor and Shape:SolidMolecular weight:426.87Netupitant
CAS:Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).Formula:C30H32F6N4OPurity:99.43%Color and Shape:SolidMolecular weight:578.59SB 242084
CAS:SB 242084 dihydrochloride hydrate is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor.Formula:C21H19ClN4O2Purity:99.75% - ≥98%Color and Shape:SolidMolecular weight:394.85CS 2100
CAS:CS 2100 (1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid) is an S1P1 agonist.
Formula:C25H23N3O4SPurity:99.19%Color and Shape:SolidMolecular weight:461.53Pimavanserin tartrate
CAS:Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist used to treat Parkinson's disease-related psychosis.Cost-effective and quality-assured.Formula:C50H68F2N6O4·C4H6O6Purity:99.24% - 99.98%Color and Shape:SolidMolecular weight:1005.2H2L 5765834
CAS:H2L 5765834 is a lysophosphatidic acid receptors antagonistFormula:C21H12N2O7Purity:98.25% - 99.47%Color and Shape:SolidMolecular weight:404.33Ref: TM-T22834
1mg58.00€5mg113.00€10mg177.00€25mg334.00€50mg497.00€100mg708.00€1mL*10mM (DMSO)124.00€9-FLUORENOL
CAS:9-FLUORENOL is a dopamine reuptake inhibitor with IC50 of 9 μM, and a major metabolite of a compound developed as a wakefulness-promoting agent.Formula:C13H10OPurity:99.98%Color and Shape:Off-White Crystalline PowderMolecular weight:182.22Almotriptan Malate
CAS:Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.Formula:C17H25N3O2S·C4H6O5Purity:99.95%Color and Shape:Pale Yellow SolidMolecular weight:469.55Namodenoson
CAS:Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.Formula:C18H18ClIN6O4Purity:98.97%Color and Shape:SolidMolecular weight:544.73Serotonin hydrochloride
CAS:Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (Formula:C10H13ClN2OPurity:98.05% - 99.93%Color and Shape:White To Cream PowderMolecular weight:212.676Glucagon (19-29), human acetate
Glucagon (19-29), human acetate a COOH-terminal fragment processed from glucagon, is a potent and efficient inhibitor of insulin secretion.Formula:C63H93N15O20SPurity:98.11%Color and Shape:SolidMolecular weight:1412.57LGnRH-III, lamprey acetate(147859-97-0 free base)
LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretionFormula:C61H78N18O16Purity:99.66%Color and Shape:SolidMolecular weight:1319.38Taminadenant
CAS:Taminadenant is an adenosine receptor antagonist.Formula:C10H8BrN7Purity:99.11%Color and Shape:SolidMolecular weight:306.12Ref: TM-T16980
2mg35.00€5mg51.00€10mg88.00€25mg120.00€50mg170.00€100mg250.00€200mg373.00€1mL*10mM (DMSO)57.00€Etrasimod
CAS:Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: 1.88 nM in CHO cells).Formula:C26H26F3NO3Purity:98.52% - 99.73%Color and Shape:SolidMolecular weight:457.48Ref: TM-TQ0227
1mg50.00€5mg105.00€10mg170.00€25mg230.00€50mg289.00€100mg401.00€1mL*10mM (DMSO)107.00€BAY 41-8543
CAS:BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
Formula:C21H21FN8OPurity:99.86%Color and Shape:SolidMolecular weight:420.44Mesdopetam hemitartrate
CAS:Mesdopetam hemitartrate antagonizes dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM) and stabilizes psychomotor function.Formula:C28H42F2N2O12S2Purity:99.98%Color and Shape:SolidMolecular weight:700.77JNJ-31020028
CAS:JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity (pIC50=8.07, human; pIC50=8.22, rat).Formula:C34H36FN5O2Purity:95.92% - 99.65%Color and Shape:SolidMolecular weight:565.68Rotigotine Hydrochloride
CAS:Rotigotine HCl, D3-preferential dopamine agonist, is 50x stronger than quinpirole in anti-Parkinson's efficacy.
Formula:C19H26ClNOSPurity:99.53% - 99.56%Color and Shape:Almost White To White Crystalline PowderMolecular weight:351.93PRX-07034 hydrochloride
CAS:PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and decreases body weight in rodents.Formula:C21H29Cl2N3O4SPurity:98.5%Color and Shape:SolidMolecular weight:490.44Otenabant hydrochloride
CAS:Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).Formula:C25H26Cl3N7OPurity:99.79% - ≥95%Color and Shape:SolidMolecular weight:546.88Bombesin acetate(31362-50-2 free base)
CAS:Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina).Formula:C73H114N24O20SPurity:98.44%Color and Shape:SolidMolecular weight:1679.92Rotigotine-
CAS:Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome.Formula:C19H25NOSPurity:98.08% - 99.59%Color and Shape:SolidMolecular weight:315.47Ref: TM-T6647
5mg50.00€10mg73.00€25mg138.00€50mg241.00€100mg358.00€200mg523.00€500mg822.00€1mL*10mM (DMSO)52.00€Blarcamesine hydrochloride
CAS:Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).Formula:C19H24ClNOPurity:99.57% - 99.9%Color and Shape:SolidMolecular weight:317.85Ref: TM-T4111
1mg35.00€2mg48.00€5mg70.00€10mg104.00€25mg207.00€50mg359.00€100mg588.00€200mg833.00€1mL*10mM (DMSO)78.00€LY2828360
CAS:LY2828360: CB2 agonist, Ki=40.3 nM; biases CB2 over CB1 with EC50s of 20.1 nM and >100 μM.Formula:C22H27ClN6OPurity:98.45% - 99.51%Color and Shape:SolidMolecular weight:426.94carfenazine
CAS:carfenazine targets the Dopamine receptor and is used for schizophrenia research.Formula:C24H31N3O2SPurity:98.06%Color and Shape:SolidMolecular weight:425.59LY 78335
CAS:LY 78335 (1-(2,3-Dichlorophenyl)ethanamine hydrochloride) is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.Formula:C8H10Cl3NPurity:99.30% - 99.81%Color and Shape:SolidMolecular weight:226.532-ATHBI
CAS:2-ATHBI is a S1P lyase inhibitor.Formula:C9H14N2O5Purity:99.10%Color and Shape:SolidMolecular weight:230.22Parethoxycaine hydrochloride
CAS:Parethoxycaine hydrochloride (2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride) is an anesthetic[1].Formula:C15H24ClNO3Purity:99.46%Color and Shape:SolidMolecular weight:301.81Ref: TM-T9397
1mg93.00€5mg182.00€10mg266.00€25mg425.00€50mg605.00€100mg803.00€200mg1,063.00€1mL*10mM (DMSO)177.00€ACTH (1-39) human
CAS:Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH (1-39), human) is an agonist of melanocortin receptor.Formula:C207H308N56O58SPurity:99.6%Color and Shape:White Lyophilised SolidMolecular weight:4541.14Ref: TM-T8231
1mg57.00€2mg82.00€5mg120.00€10mg192.00€25mg409.00€50mg590.00€100mg827.00€200mg1,108.00€Endothelin-2 (49-69), human
CAS:Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.Formula:C115H160N26O32S4Purity:98.26%Color and Shape:SolidMolecular weight:2546.92Ornipressin Acetate(3397-23-7,free)
CAS:Ornipressin Acetate (POR-8) is a potent vasoconstrictor, hemostatic and renal agent.Formula:C47H67N13O124S2Purity:>99.99%Color and Shape:SolidMolecular weight:1102.25Acitazanolast
CAS:Acitazanolast (WP-871) is an anti-allergic drug candidate.
Formula:C9H7N5O3Purity:98.25%Color and Shape:SolidMolecular weight:233.18Emorfazone
CAS:Emorfazone (PH011085) has an anti-nociceptive effect.Formula:C11H17N3O3Purity:99.89%Color and Shape:SolidMolecular weight:239.27Ref: TM-T9132
1mg84.00€5mg168.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€1mL*10mM (DMSO)152.00€TRAP-6 amide acetate
TRAP-6 amide acetate is a PAR-1 thrombin receptor agonist peptide[1].
Formula:C36H61N11O10Purity:98.55%Color and Shape:SolidMolecular weight:807.94cicloprofen
CAS:cicloprofen is Cell division cycle 7-related protein kinase (human) inhibitor.Formula:C16H14O2Purity:98.15%Color and Shape:SolidMolecular weight:238.2812Ref: TM-T8586
1mg62.00€5mg123.00€10mg180.00€25mg298.00€50mg419.00€100mg567.00€200mg752.00€1mL*10mM (DMSO)111.00€Melperone
CAS:Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.Formula:C16H22FNOPurity:98.84%Color and Shape:SolidMolecular weight:263.35Grapiprant
CAS:Grapiprant (AAT-007) is a selective EP4 receptor antagonist.Formula:C26H29N5O3SPurity:99.49% - 99.843%Color and Shape:SolidMolecular weight:491.61GSK163090
CAS:GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).Formula:C25H29N5OPurity:99.2%Color and Shape:SolidMolecular weight:415.53Ref: TM-TQ0311
1mg34.00€2mg49.00€5mg75.00€10mg118.00€25mgTo inquire50mgTo inquire1mL*10mM (DMSO)82.00€Histrelin acetate
CAS:Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency.Formula:C68H90N18O14Purity:99.92%Color and Shape:SolidMolecular weight:1383.55Alprenolol benzoate
CAS:Alprenolol benzoate is the benzoate salt of Alprenolol -- a beta blocker.Formula:C22H29NO4Color and Shape:SolidMolecular weight:371.48DOPEXAMINE
CAS:Dopexamine is a dopaminergic agonistFormula:C22H32N2O2Purity:99.42%Color and Shape:SolidMolecular weight:356.5Ref: TM-T8653
1mg131.00€2mg188.00€5mg284.00€10mg430.00€25mg710.00€50mg998.00€100mg1,349.00€1mL*10mM (DMSO)306.00€Tianeptine
CAS:Tianeptine (Tianeptine sodium) 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。Formula:C21H25ClN2O4SPurity:99.04%Color and Shape:SolidMolecular weight:436.95TG4-155
CAS:TG4-155: brain-penetrant EP2 inhibitor, KB 2.4 nM; >1000x weaker at EP4, KB 11.4 μM; selective over other receptors/channels.
Formula:C23H26N2O4Purity:97.2%Color and Shape:SolidMolecular weight:394.46Neuropeptide S (Rat) acetate
Neuropeptide S (Rat) acetate is an endogenous ligand of a previously orphan G-protein-coupled receptor now named NPS receptor.Formula:C97H164N34O29Purity:95.36%Color and Shape:SolidMolecular weight:2270.59Ref: TM-TP1982L
1mg87.00€2mg124.00€5mg192.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€BRL-15572 dihydrochloride
CAS:BRL-15572 dihydrochloride: 5-HT1D antagonist, pKi 7.9, also binds 5-HT1A/2B, 60x selective over 5-HT1B.Formula:C25H27ClN2O·2HClPurity:99.74%Color and Shape:SolidMolecular weight:479.87BisfluoroModafinil
CAS:CRL-40940 is a selective dopaminergic reuptake inhibitorFormula:C15H13F2NO2SPurity:99.19%Color and Shape:SolidMolecular weight:309.33
