GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,030 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(159 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(196 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(42 products)
- Opioid Receptor(325 products)
- PAFR(14 products)
- PKA(55 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5985 products of "GPCR/G-Protein"
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D3-βArr
CAS:D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by directFormula:C20H23N5Purity:98.82%Color and Shape:SolidMolecular weight:333.43Ropinirole hydrochloride
CAS:Ropinirole HCl (SKF-101468A) is a selective D2 dopamine agonist (Ki: 29 nM) with antiparkinsonian effects.Formula:C16H24N2O·HClPurity:99.87% - 99.98%Color and Shape:Off-White SolidMolecular weight:296.84Hypidone hydrochloride
CAS:Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitorFormula:C18H23ClN2O2Purity:99.82% - 99.93%Color and Shape:SolidMolecular weight:334.84Acrivastine
CAS:Acrivastine (Acrivastin) is a short-acting histamine 1 receptor antagonist.Formula:C22H24N2O2Purity:99.73% - >99.99%Color and Shape:SolidMolecular weight:348.44Melitracen hydrochloride
CAS:Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Formula:C21H26ClNPurity:99.99%Color and Shape:Crystalline SolidMolecular weight:327.90Ref: TM-T4274
10mg44.00€25mg64.00€50mg93.00€100mg110.00€200mg161.00€500mg264.00€1mL*10mM (DMSO)48.00€Tasimelteon
CAS:Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.Formula:C15H19NO2Purity:98.93% - 99.93%Color and Shape:SolidMolecular weight:245.32Doxazosin
CAS:Doxazosin (UK 33274) is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.Formula:C23H25N5O5Purity:99.47% - 99.87%Color and Shape:SolidMolecular weight:451.48Relugolix
CAS:Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, withFormula:C29H27F2N7O5SPurity:98.64% - 99.97%Color and Shape:SolidMolecular weight:623.63Ref: TM-T3630
2mg39.00€5mg58.00€10mg93.00€25mg167.00€50mg250.00€100mg408.00€200mg585.00€1mL*10mM (DMSO)81.00€Protease-Activated Receptor-4 diTFA
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonistFormula:C37H48F6N8O11Purity:98.54%Color and Shape:SolidMolecular weight:894.81Ref: TM-T7740
1mg48.00€2mg60.00€5mg86.00€10mg138.00€25mg274.00€50mg411.00€100mg607.00€1mL*10mM (DMSO)170.00€Clozapine HCl
CAS:Clozapine HCl, an atypical antipsychotic, binds CNS receptors, targets 5-HT2A/2C, has weaker D2 antagonism. Risk: Agranulocytosis.Formula:C18H20Cl2N4Color and Shape:SolidMolecular weight:363.29ML-191
CAS:ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.Formula:C24H25N3O3Purity:99.58%Color and Shape:SolidMolecular weight:403.47Peptide YY (PYY) (3-36), human
CAS:Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.Formula:C176H272N52O54Purity:97.76%Color and Shape:SolidMolecular weight:3980.42JNJ-37822681
CAS:JNJ-37822681 is a novel, highly selective dopamine D₂ receptor antagonist characterized by a rapid dissociation rate from the dopamine D₂ receptor.Formula:C17H17F5N4Purity:99.84%Color and Shape:SolidMolecular weight:372.34A2B receptor antagonist 2
CAS:A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).Formula:C12H15N5Purity:100%Color and Shape:SolidMolecular weight:229.28Bavisant dihydrochloride hydrate
CAS:Bavisant dihydrochloride (JNJ31001074AAC) is an oral H3 receptor antagonist for ADHD treatment. Phase 2 trials show no significant benefits at 10 mg/day.Formula:C19H31Cl2N3O3Color and Shape:SolidMolecular weight:420.38lumateperone Tosylate
CAS:lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist, a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors.Formula:C31H36FN3O4SPurity:95.83% - 99.95%Color and Shape:SolidMolecular weight:565.7Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-Formula:C24H35ClO9Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:502.98Hydroxyzine dihydrochloride
CAS:Hydroxyzine dihydrochloride treats allergies, pruritus, anxiety; causes drowsiness; also an antiemetic and sedative.Formula:C21H27ClN2O2·2HClPurity:99.46% - 99.79%Color and Shape:Oil PowderMolecular weight:447.83Mecamylamine
CAS:Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.Formula:C11H21NColor and Shape:SolidMolecular weight:167.29Neuropeptide S (Rat) acetate
Neuropeptide S (Rat) acetate is an endogenous ligand of a previously orphan G-protein-coupled receptor now named NPS receptor.Formula:C97H164N34O29Purity:95.36%Color and Shape:SolidMolecular weight:2270.59Ref: TM-TP1982L
1mg87.00€2mg124.00€5mg192.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€BML-190
CAS:BML-190 (Indomethacin morpholinylamide) 是一种 CB2 受体的配体，其对 CB2 受体 (Ki:435 nM) 和 CB1受体 (Ki> 2 μM)。Formula:C23H23ClN2O4Purity:97.70%Color and Shape:SolidMolecular weight:426.89(±)-Ibipinabant
CAS:(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.Formula:C23H20Cl2N4O2SPurity:99.28% - 99.83%Color and Shape:SolidMolecular weight:487.4BRL-15572 hydrochloride
CAS:BRL-15572 hydrochloride: selective h5-HT1D antagonist with high affinity; useful for studying h5-HT1D responses.Formula:C25H28Cl2N2OColor and Shape:SolidMolecular weight:443.41VKGILS-NH2 Acetate
VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.Formula:C30H58N8O9Purity:98.83%Color and Shape:SolidMolecular weight:674.83Ref: TM-T21699L
1mg34.00€2mg52.00€5mg65.00€10mg97.00€25mg163.00€50mg235.00€100mg349.00€200mg497.00€1mL*10mM (DMSO)97.00€Trimethobenzamide hydrochloride
CAS:Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.Formula:C21H29ClN2O5Purity:99.52%Color and Shape:SolidMolecular weight:424.92Obestatin (rat) acetate
Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39).Formula:C114H174N34O31Purity:99.05%Color and Shape:SolidMolecular weight:2516.81Ref: TM-TP2279L
1mg77.00€2mg97.00€5mg156.00€10mg225.00€25mg375.00€50mg535.00€100mg730.00€200mg938.00€AdipoRon hydrochloride
CAS:AdipoRon hydrochloride is a specific, orally active AdipoR agonist, capable of binding AdipoR1 (Kd: 1.8 μM) and AdipoR2 (Kd: 3.1 μM).Formula:C27H29ClN2O3Color and Shape:SolidMolecular weight:464.991-[(5-methylisoxazol-3-yl)methyl]piperazine
CAS:1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI)) is a P2Y12 inhibitor.
Formula:C9H15N3OPurity:95%Color and Shape:SolidMolecular weight:181.23CRF (6-33) acetate(120066-38-8 free base)
CRFBP inhibitor peptide; reduces weight gain, boosts activity in obese rats.Formula:C143H235N41O45SPurity:97.12%Color and Shape:SolidMolecular weight:3280.76Midodrine
CAS:Midodrine ((±)-Midodrin), an adrenergic alpha-1 agonist, belongs to the class of medications known as vasopressors.Formula:C12H18N2O4Purity:99.89%Color and Shape:SolidMolecular weight:254.28Ditolylguanidine
CAS:Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).Formula:C15H17N3Purity:98.42%Color and Shape:White To Pinkish Solid PowderMolecular weight:239.32Tiapride
CAS:Tiapride, an atypical neuroleptic, is a selective dopamine D2-receptor antagonist with varying IC50 values for D1-D4.Formula:C15H24N2O4SColor and Shape:SolidMolecular weight:328.43BRL-15572 dihydrochloride
CAS:BRL-15572 dihydrochloride: 5-HT1D antagonist, pKi 7.9, also binds 5-HT1A/2B, 60x selective over 5-HT1B.Formula:C25H27ClN2O·2HClPurity:99.74%Color and Shape:SolidMolecular weight:479.87Cariprazine hydrochloride
CAS:Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)Formula:C21H33Cl3N4OPurity:99.78% - >99.99%Color and Shape:SolidMolecular weight:463.87Spexin acetate(1370290-58-6 free base)
Spexin acetate: GAL2/GAL3 agonist. EC50: 45.7/112.2 nM. Inactive at GAL1. Reduces appetite, fat uptake, and food intake; lowers LH in fish; anxiolytic.Formula:C76H117N19O22SPurity:95.43%Color and Shape:SolidMolecular weight:1680.94Quipazine
CAS:Quipazine: 5-HT agonist, Ki 1.4 nM at 5-HT3R, anti-SARS-CoV-2 (EC50 31.64 μM), for neurological research.Formula:C13H15N3Color and Shape:SolidMolecular weight:213.28Glucagon-like peptide 1 (1-37), human acetate
Glucagon-like peptide 1 (1-37), human acetate is a highly potent the GLP-1 receptor agonist.Purity:98%Color and Shape:LiquidMolecular weight:N/ABrefonalol
CAS:Brefonalol is a vasodilating beta-adrenergic receptor blocker.
Formula:C22H28N2O2Color and Shape:SolidMolecular weight:352.47carfenazine
CAS:carfenazine targets the Dopamine receptor and is used for schizophrenia research.
Formula:C24H31N3O2SPurity:98.06%Color and Shape:SolidMolecular weight:425.59Opiranserin hydrochloride
CAS:Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μMFormula:C21H35ClN2O5Purity:99.33%Color and Shape:SolidMolecular weight:430.97Ref: TM-T9833
1mg90.00€5mg215.00€10mg340.00€25mg618.00€50mg879.00€100mg1,224.00€500mg2,457.00€1mL*10mM (DMSO)236.00€Oxyntomodulin acetate
Oxyntomodulin acetate, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1].Purity:99.24%Color and Shape:LiquidMolecular weight:N/ABRL 54443
CAS:BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively).Formula:C14H18N2OPurity:98.07%Color and Shape:SolidMolecular weight:230.31BIBO3304
CAS:BIBO3304: Selective NPY Y1 blocker, IC50 of 0.38nM (human), 0.72nM (rat); curbs hunger from NPY/fasting when injected centrally.Formula:C29H35N7O3Color and Shape:SolidMolecular weight:529.63Bradykinin (acetate)
CAS:Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system.Formula:C52H77N15O13Purity:>99.99%Color and Shape:SolidMolecular weight:1120.26ANP(1-28) Acetate (human, porcine)
CAS:Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.Formula:C129H207N45O41S3Purity:98.24%Color and Shape:SolidMolecular weight:3140.5Ref: TM-TP1220L
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,388.00€100mg1,872.00€200mg2,527.00€SB-334867 free base
CAS:SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.Formula:C17H13N5O2Purity:99.67% - >99.99%Color and Shape:SolidMolecular weight:319.32Ref: TM-T6140
2mg42.00€5mg70.00€10mg99.00€25mg160.00€50mg226.00€100mg338.00€200mg502.00€1mL*10mM (DMSO)78.00€Raclopride tartrate
CAS:Raclopride is a selective antagonist on D2 dopamine receptor ( D2 Ki: 1.8 nm, D3 Ki: 3.5 nm, D4 Ki: 2400, D1 Ki: 18000 nM).Formula:C19H26Cl2N2O9Color and Shape:SolidMolecular weight:497.32Ibutamoren Mesylate
CAS:Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.Formula:C28H40N4O8S2Purity:97.98% - ≥98%Color and Shape:SolidMolecular weight:624.77MK 212 hydrochloride
CAS:MK 212 hydrochloride is a 5-HT2C receptor agonistFormula:C8H11ClN4·HClPurity:99.88%Color and Shape:SolidMolecular weight:235.12Mini Gastrin I, human acetate
Mini Gastrin I, human acetate is a shorter version of human gastrin, consists of amino acids 5-17 of the parent peptide.Formula:C76H103N15O28SPurity:99.35% - 99.82%Color and Shape:SolidMolecular weight:1706.78
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