GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(942 products)
- Adenosine Receptor(242 products)
- Adrenergic Receptor(2,949 products)
- Bombesin Receptor(30 products)
- Bradykinin Receptor(59 products)
- CXCR(149 products)
- CaSR(32 products)
- Cannabinoid Receptor(195 products)
- Dopamine Receptor(410 products)
- Endothelin Receptor(75 products)
- GNRH Receptor(73 products)
- GPCR19(31 products)
- GRK(32 products)
- GTPase(21 products)
- Glucagon Receptor(166 products)
- Hedgehog/Smoothened(45 products)
- Histamine Receptor(359 products)
- LPA Receptor(21 products)
- Melatonin Receptor(24 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
- PAFR(11 products)
- PKA(49 products)
- S1P Receptor(17 products)
- SGLT(30 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5378 products of "GPCR/G-Protein"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BX471
CAS:<p>BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.</p>Formula:C21H24ClFN4O3Purity:98% - 99.94%Color and Shape:SolidMolecular weight:434.89Tolazoline
CAS:<p>Tolazoline (Benzalolin), a vasodilator, treats vessel spasms and reverses 5-HT2A drug overdose effects.</p>Formula:C10H12N2Purity:99.52%Color and Shape:SolidMolecular weight:160.22Jatrorrhizine
CAS:Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species.Formula:C20H20NO4Purity:97.18% - 99.06%Color and Shape:SolidMolecular weight:338.38Etelcalcetide hydrochloride
CAS:<p>Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.</p>Formula:C38H73N21O10S2HClPurity:>99.99%Color and Shape:SolidMolecular weight:1353.33Talastine HCl
CAS:<p>Talastine is an antihistamine drug.</p>Formula:C19H22ClN3OPurity:98%Color and Shape:SolidMolecular weight:343.86Tafluprost
CAS:<p>Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α.</p>Formula:C25H34F2O5Purity:97.7% - 99.67%Color and Shape:LiquidMolecular weight:452.53CB1-IN-1
CAS:CB1-IN-1 (DBPR211) is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.Formula:C33H31Cl2F3N6O3S2Purity:99.08% - 99.76%Color and Shape:SolidMolecular weight:751.67Eltoprazine
CAS:<p>Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.</p>Formula:C12H16N2O2Color and Shape:SolidMolecular weight:220.27Melanin Concentrating Hormone, salmon acetate
<p>Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.</p>Formula:C91H143N27O26S4Purity:99.41%Color and Shape:SolidMolecular weight:2157Bay 55-9837 acetate
Bay 55-9837 acetate is a potent and highly selective VPAC2 agonist(Kd = 0.65 nM) and can be used in type 2 diabetes studies.Purity:98.27%Color and Shape:LiquidMolecular weight:N/AAM281
CAS:<p>AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.</p>Formula:C21H19Cl2IN4O2Purity:98.6% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:557.21Veralipride
CAS:<p>Veralipride ((±)-Veralipride) is an antagonist of D2 receptor.</p>Formula:C17H25N3O5SPurity:99.65%Color and Shape:SolidMolecular weight:383.46OXA (17-33) acetate
<p>OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).</p>Formula:C79H125N23O22Purity:98.52%Color and Shape:SolidMolecular weight:1748.98RBC8
CAS:<p>RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.</p>Formula:C25H20N4O3Purity:98.44% - 99.81%Color and Shape:SolidMolecular weight:424.45Blarcamesine hydrochloride
CAS:Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).Formula:C19H24ClNOPurity:99.57% - 99.9%Color and Shape:SolidMolecular weight:317.85ML 154
CAS:<p>ML 154 is a potent neuropeptide S receptor (NPSR) antagonist.</p>Formula:C29H26BrN2PSPurity:99.53%Color and Shape:SolidMolecular weight:545.47PF-06882961 Tris
CAS:<p>PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>Formula:C35H41FN6O7Purity:98.74% - 99.79%Color and Shape:SolidMolecular weight:676.7Darbufelone mesylate
CAS:Darbufelone mesylate blocks PGF2α, LTB4, PGHS-2 (IC50: 0.19 μM), and PGHS-1 (IC50: 20 μM).Formula:C19H28N2O5S2Purity:96.81% - 99.92%Color and Shape:SolidMolecular weight:428.57MK 212 hydrochloride
CAS:<p>MK 212 hydrochloride is a 5-HT2C receptor agonist</p>Formula:C8H11ClN4·HClPurity:99.88%Color and Shape:SolidMolecular weight:235.12carfenazine
CAS:<p>carfenazine targets the Dopamine receptor and is used for schizophrenia research.</p>Formula:C24H31N3O2SPurity:98.06%Color and Shape:SolidMolecular weight:425.59Peptide YY (PYY) (3-36), human
CAS:<p>Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.</p>Formula:C176H272N52O54Purity:97.76%Color and Shape:SolidMolecular weight:3980.42ELN-441958
CAS:<p>ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM.</p>Formula:C29H29ClN4O2Purity:99.88%Color and Shape:SolidMolecular weight:501.023-AQC
CAS:<p>3-AQC is a competitive antagonist of 5-HT3.</p>Formula:C20H21N5O4Purity:99.45%Color and Shape:SolidMolecular weight:395.41EST64454 hydrochloride
CAS:<p>EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.</p>Formula:C18H23ClF2N4O2Purity:99.15%Color and Shape:SolidMolecular weight:400.85ARN272
CAS:<p>ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).</p>Formula:C27H20N4O2Purity:98.23%Color and Shape:SolidMolecular weight:432.47Opromazine hydrochloride
CAS:<p>Opromazine hydrochloride, a phenothiazine antipsychotic, blocks brain dopamine receptors to treat schizophrenia and psychosis.</p>Formula:C17H20Cl2N2OSPurity:98.03%Color and Shape:SolidMolecular weight:371.32SB-203186 hydrochloride
CAS:<p>SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist</p>Formula:C16H20N2O2·HClPurity:99.64%Color and Shape:SolidMolecular weight:308.81Pridopidine
CAS:<p>Pridopidine (FR310826), a low-affinity D2R antagonist, enhances motor skills and has neuroprotective effects in Huntington's R6/2 mice.</p>Formula:C15H23NO2SPurity:95.2% - 99.89%Color and Shape:SolidMolecular weight:281.41Abaperidone Hydrochloride
CAS:<p>Abaperidone Hydrochloride is an atypical antipsychotic, potently binging to5-HT2 receptors and D2 receptors.</p>Formula:C25H26ClFN2O5Color and Shape:SolidMolecular weight:488.94Tianeptine
CAS:Tianeptine (Tianeptine sodium) 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。Formula:C21H25ClN2O4SPurity:99.04%Color and Shape:SolidMolecular weight:436.95[Lys8, Lys9]-Neurotensin (8-13) acetate
<p>[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2</p>Formula:C40H68N8O10Purity:99.31%Color and Shape:SolidMolecular weight:821.02REV 5901
CAS:<p>REV 5901: oral leukotriene receptor antagonist and 5-lipoxygenase inhibitor with Ki of 0.7 μM, researched for asthma.</p>Formula:C22H25NO2Color and Shape:SolidMolecular weight:335.445-Benzyloxygramine
CAS:5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.Formula:C18H20N2OPurity:99.13%Color and Shape:SolidMolecular weight:280.36IPSU
CAS:<p>IPSU is an antagonist of OX2 receptor. IPSU Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors.</p>Formula:C23H27N5O2Purity:97.05%Color and Shape:SolidMolecular weight:405.49Emorfazone
CAS:Emorfazone (PH011085) has an anti-nociceptive effect.Formula:C11H17N3O3Purity:99.89%Color and Shape:SolidMolecular weight:239.27CYM2503
CAS:<p>CYM2503 is a GAL2 receptor PAM enhancing galanin-induced IP1 without binding the galanin site.</p>Formula:C45H55N5O7Purity:97.04%Color and Shape:SolidMolecular weight:777.95Talinolol
CAS:(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.Formula:C20H33N3O3Purity:98.8%Color and Shape:SolidMolecular weight:363.49JNJ-5207852
CAS:JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor.Formula:C20H32N2OPurity:97.19%Color and Shape:SolidMolecular weight:316.48ABT-724
CAS:<p>ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM)</p>Formula:C17H19N5Purity:99.73%Color and Shape:SolidMolecular weight:293.37LGnRH-III, lamprey acetate(147859-97-0 free base)
<p>LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretion</p>Formula:C61H78N18O16Purity:99.66%Color and Shape:SolidMolecular weight:1319.38BD1063 dhydrochloride
CAS:BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).Formula:C13H20Cl4N2Purity:99.52% - ≥95%Color and Shape:SolidMolecular weight:346.12Taminadenant
CAS:<p>Taminadenant is an adenosine receptor antagonist.</p>Formula:C10H8BrN7Purity:99.11%Color and Shape:SolidMolecular weight:306.12Pardoprunox hydrochloride
CAS:Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1)Formula:C12H16ClN3O2Purity:98.95% - 99.13%Color and Shape:SolidMolecular weight:269.73Reboxetine mesylate
CAS:<p>Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor (Ki: 8.2 nM).</p>Formula:C19H23NO3·CH4O3SPurity:99.18% - 99.87%Color and Shape:Tan Or Off-White Cyrstalline SolidMolecular weight:409.5Betazole dihydrochloride
CAS:<p>Betazole dihydrochloride (Betazole hydrochloride) is an agonist of H2 receptor.</p>Formula:C5H11Cl2N3Purity:99.12%Color and Shape:SolidMolecular weight:184.067CRF (6-33) acetate(120066-38-8 free base)
<p>CRFBP inhibitor peptide; reduces weight gain, boosts activity in obese rats.</p>Formula:C143H235N41O45SPurity:97.12%Color and Shape:SolidMolecular weight:3280.76Cinacalcet hydrochloride
CAS:<p>Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-</p>Formula:C22H23ClF3NPurity:99.96% - >99.99%Color and Shape:Off-White To Tan SolidMolecular weight:393.87BAY 41-8543
CAS:<p>BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).</p>Formula:C21H21FN8OPurity:99.86%Color and Shape:SolidMolecular weight:420.44Ursodeoxycholic acid sodium
CAS:<p>Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities.</p>Formula:C24H40NaO4Purity:99.66% - 99.96%Color and Shape:SolidMolecular weight:415.56PF-06291874
CAS:<p>PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor.</p>Formula:C26H28F3N3O4Purity:99.12% - 99.27%Color and Shape:SolidMolecular weight:503.51
![[Lys8, Lys9]-Neurotensin (8-13) acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT38807L.webp&w=3840&q=75)
