
GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(942 products)
- Adenosine Receptor(242 products)
- Adrenergic Receptor(2,949 products)
- Bombesin Receptor(30 products)
- Bradykinin Receptor(59 products)
- CXCR(149 products)
- CaSR(32 products)
- Cannabinoid Receptor(195 products)
- Dopamine Receptor(410 products)
- Endothelin Receptor(75 products)
- GNRH Receptor(73 products)
- GPCR19(31 products)
- GRK(32 products)
- GTPase(21 products)
- Glucagon Receptor(166 products)
- Hedgehog/Smoothened(45 products)
- Histamine Receptor(359 products)
- LPA Receptor(21 products)
- Melatonin Receptor(24 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
- PAFR(11 products)
- PKA(49 products)
- S1P Receptor(17 products)
- SGLT(30 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5378 products of "GPCR/G-Protein"
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FAUC 346
CAS:<p>FAUC 346 is a highly selective D3 partial agonist with EC50 of 1.5 nM.</p>Formula:C24H29N3O2SPurity:99.46%Color and Shape:SolidMolecular weight:423.57ML-178
CAS:<p>ML-178: selective S1PR4 agonist, EC50 of 46 nM; inactive on other S1P receptors at 25 μM.</p>Formula:C13H9Br2Cl2NO2Purity:95.92%Color and Shape:SolidMolecular weight:441.93H4 Receptor antagonist 1
CAS:H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.Formula:C16H17ClN4OPurity:98.81%Color and Shape:SolidMolecular weight:316.791-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID
CAS:<p>1-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID targets GRK2.</p>Formula:C13H13NO5Purity:99.55%Color and Shape:SolidMolecular weight:263.25Trazodone
CAS:<p>Trazodone (AF-1161), a 5-HT 2A/2C receptor antagonist, is used as an antidepressant for treating major anxiety disorders and depressive disorder.</p>Formula:C19H22ClN5OPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:371.86Harmine
CAS:<p>Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.</p>Formula:C13H12N2OPurity:98.29% - 99.92%Color and Shape:Off-White SolidMolecular weight:212.25Pramipexole dihydrochloride hydrate
CAS:<p>Pramipexole dihydrochloride hydrate (Mirapex) is a selective, blood-brain barrier-crossing D2 dopamine receptor agonist, and is used in the study of PD.</p>Formula:C10H17N3S·2HCl·H2OPurity:99.68%Color and Shape:White To Off-White Crystalline PowderMolecular weight:302.265-Iodotubercidin
CAS:<p>5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM.</p>Formula:C11H13IN4O4Purity:99.98%Color and Shape:Tan SolidMolecular weight:392.15Relenopride hydrochloride
CAS:<p>Relenopride, a 5-HT agonist, is used potentially for the treatment of chronic constipation.</p>Formula:C24H31Cl2FN4O4Color and Shape:SolidMolecular weight:529.43ELA-11 (human) acetate(1784687-32-6 free base)
<p>ELA-11: potent apelin receptor agonist, Ki=14 nM. Blocks cAMP, boosts β-arrestin. Part of ELA-32.</p>Formula:C60H94N16O15S2Purity:99.53%Color and Shape:SolidMolecular weight:1343.61Dobutamine tartrate
CAS:<p>Dobutamine tartrate is a cardiotonic.</p>Formula:C22H29NO9Color and Shape:SolidMolecular weight:451.472Afamelanotide acetate
CAS:<p>Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist.</p>Formula:C80H115N21O21Purity:98% - 99.494%Color and Shape:SolidMolecular weight:1706.9NPS2390
CAS:<p>NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)</p>Formula:C19H21N3OPurity:97.13%Color and Shape:SolidMolecular weight:307.39Talnetant hydrochloride
CAS:<p>Talnetant (SB 223412) hydrochloride, an NK3 antagonist, selectively binds hNK-3 at 1.4 nM, much less to hNK-2, none to hNK-1 at 100 μM.</p>Formula:C25H23ClN2O2Color and Shape:SolidMolecular weight:418.92Poloxamer 407
CAS:<p>Poloxamer 407 is a nonionic surfactant.</p>Purity:98%Color and Shape:White Crystalline PowderMolecular weight:7700(Average)Tandospirone hydrochloride
CAS:<p>Tandospirone (SM-3997) HCl: potent 5-HT1A partial agonist; Ki: 27 nM; anxiolytic, antidepressant, for CNS disorder research.</p>Formula:C21H30ClN5O2Color and Shape:SolidMolecular weight:419.95ML-191
CAS:<p>ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.</p>Formula:C24H25N3O3Purity:99.58%Color and Shape:SolidMolecular weight:403.47Eltoprazine dihydrochloride
CAS:<p>Eltoprazine dihydrochloride, a drug developed for aggression, is now studied for L-DOPA-induced dyskinesia in Parkinson's.</p>Formula:C12H18Cl2N2O2Purity:99.64%Color and Shape:SolidMolecular weight:293.19BCTC
CAS:<p>BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)</p>Formula:C20H25ClN4OPurity:99.21%Color and Shape:SolidMolecular weight:372.89Loxapine hydrochloride
CAS:<p>Loxapine hydrochloride, an oral anti-psychotic, inhibits dopamine and blocks 5-HT receptors.</p>Formula:C18H19Cl2N3OColor and Shape:SolidMolecular weight:364.27CYM 50358 hydrochloride (1314212-39-9 free base)
CAS:CYM50358 HCl is an S1P4 antagonist.Formula:C20H19Cl3N2O2Purity:99.57%Color and Shape:SolidMolecular weight:425.73GR 125743
CAS:GR 125743 is a novel antagonist of 5-HT1B/1D receptor.Formula:C25H28N4O2Purity:99.76%Color and Shape:SolidMolecular weight:416.52SB 242084 dihydrochloride
CAS:SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.Formula:C21H21Cl3N4O2Color and Shape:SolidMolecular weight:467.78HAEGTFTSDVSSYLE
<p>HAEGTFTSDVSSYLE is a peptide. GLP-I analog contains the sequence.</p>Formula:C71H103N17O28Purity:>99.99%Color and Shape:SolidMolecular weight:1642.71Alimemazine hemitartrate
CAS:<p>Alimemazine hemitartrate (Trimeprazine hemitartrate) is aphenothiazine derivative that is used as an antipruritic.</p>Formula:C18H22N2SC4H6O6Purity:98.16% - 99.69%Color and Shape:SolidMolecular weight:448.53CCR2 antagonist 4 hydrochloride
CAS:CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).Formula:C21H22Cl2F3N3O2Color and Shape:SolidMolecular weight:476.32CYM-5520
CAS:<p>CYM-5520 is a noncompetitive allosteric agonist of S1P2</p>Formula:C21H19N3O2Purity:99.47%Color and Shape:SolidMolecular weight:345.39Samelisant dihydrochloride
CAS:<p>SUVN-G3031: H3 receptor antagonist; may treat cognitive issues, ADHD, epilepsy, sleep, obesity, schizophrenia, eating disorders, pain.</p>Formula:C21H33Cl2N3O3Color and Shape:SolidMolecular weight:446.41Bevantolol
CAS:<p>Bevantolol, a selective β-1 adrenoceptor antagonist, is utilized for the investigation of angina pectoris and hypertension [1].</p>Formula:C20H27NO4Color and Shape:SolidMolecular weight:345.43Quipazine maleate
CAS:<p>Quipazine maleate is a 5-HT agonist affecting L-02 hepatocytes and raphe neurons, causing smooth muscle contracture and bronchospasm.</p>Formula:C17H19N3O4Color and Shape:SolidMolecular weight:329.36Sigma-LIGAND-1 hydrochloride
CAS:<p>Sigma-LIGAND-1 HCl: selective sigma receptor ligand; DTG IC50: 16 nM, PPP IC50: 19 nM; weak D2 receptor affinity, Ki: 4000 nM.</p>Formula:C27H34ClNO4Color and Shape:SolidMolecular weight:472.02Niaprazine
CAS:<p>Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.</p>Formula:C20H25FN4OPurity:99.56%Color and Shape:SolidMolecular weight:356.44γ-L-Glutamyl-L-alanine
CAS:<p>γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is the substrate of CRF21 (gamma-Glutamylcyclotransferase, GGCT).</p>Formula:C8H14N2O5Purity:99.49%Color and Shape:SolidMolecular weight:218.21YIL781 hydrochloride
CAS:<p>YIL781 is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM) with no significant affinity for the motilin receptor (Ki = 6 μM).</p>Formula:C24H29ClFN3O2Color and Shape:SolidMolecular weight:445.96Dolasetron Mesylate hydrate
CAS:<p>Dolasetron Mesylate hydrate blocks 5HT3 to prevent chemo and radiotherapy nausea.</p>Formula:C20H26N2O7SPurity:99.86% - 99.9%Color and Shape:SolidMolecular weight:438.49BMY-25368
CAS:<p>BMY-25368 is a long-acting antagonist of the H2-receptor.</p>Formula:C19H25N3O3Color and Shape:SolidMolecular weight:343.42Fertirelin
CAS:<p>Fertirelin, or fertirelin acetate, sold under the brand name Ovalyse, is a gonadotropin-releasing hormone agonist (GnRH agonist).</p>Formula:C55H76N16O12Purity:>99.99%Color and Shape:SolidMolecular weight:1153.29Seltorexant hydrochloride
CAS:<p>Seltorexant hydrochloride is a selective, orally active and high-affinity antagonist of OX2R with pKi values of 8.0 and 8.1 for human and rat OX2R.</p>Formula:C21H23ClFN7OPurity:98%Color and Shape:SolidMolecular weight:443.91Ritanserin
CAS:<p>Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist.Cost-effective and quality-assured.</p>Formula:C27H25F2N3OSPurity:99.77% - 99.89%Color and Shape:SolidMolecular weight:477.57MK 571
CAS:<p>MK 571 (L660711) is an orally active antagonist of CysLT1 receptor.</p>Formula:C26H27ClN2O3S2Purity:98.69% - 99.65%Color and Shape:SolidMolecular weight:515.09Mecamylamine
CAS:<p>Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.</p>Formula:C11H21NColor and Shape:SolidMolecular weight:167.29CRF (6-33) acetate(120066-38-8 free base)
<p>CRFBP inhibitor peptide; reduces weight gain, boosts activity in obese rats.</p>Formula:C143H235N41O45SPurity:97.12%Color and Shape:SolidMolecular weight:3280.76TNCA
CAS:<p>TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.</p>Formula:C12H12N2O2Purity:97.33% - 97.73%Color and Shape:SolidMolecular weight:216.24Clobenpropit 2HBr
CAS:<p>Clobenpropit 2HBr is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in the brain.</p>Formula:C14H17ClN4SColor and Shape:SolidMolecular weight:308.83Bromodiphenhydramine hydrochloride
CAS:<p>Bromodiphenhydramine hydrochloride is a new antihistaminic in the control of cutaneous.</p>Formula:C17H21BrClNOPurity:97.29%Color and Shape:SolidMolecular weight:370.71Nonapeptide-1
CAS:<p>Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.</p>Formula:C61H87N15O9SPurity:100%Color and Shape:SolidMolecular weight:1206.5ACTH 1-14 acetate(25696-21-3 free base)
<p>ACTH 1-14 acetate regulates cortisol and androgen, is part of the hypothalamic-pituitary-adrenal stress response.</p>Formula:C79H113N21O22SPurity:>99.99%Color and Shape:SolidMolecular weight:1740.96Ambrisentan sodium
CAS:<p>Ambrosentan (BSF 208075) sodium is a selective and oral effective antagonist of ET type A receptor ( ETAR ).</p>Formula:C22H21N2NaO4Color and Shape:SolidMolecular weight:400.41LM11A-31 dihydrochloride
CAS:<p>LM11A-31 dihydrochloride is a water-soluble, BBB-penetrating p75NTR ligand and proNGF antagonist.</p>Formula:C12H27Cl2N3O2Purity:99.9%Color and Shape:SolidMolecular weight:316.27AdipoRon
CAS:<p>AdipoRon (SC-396658) is an orally bioavailable adiponectin receptor agonist. It can combine with AdipoR1/2 (KD: 1.8/3.1 μM).</p>Formula:C27H28N2O3Purity:97.90% - 99.86%Color and Shape:SolidMolecular weight:428.52
