GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(985 products)
- Adenosine Receptor(244 products)
- Adrenergic Receptor(2,991 products)
- Bombesin Receptor(32 products)
- Bradykinin Receptor(59 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(209 products)
- Dopamine Receptor(433 products)
- Endothelin Receptor(79 products)
- GNRH Receptor(77 products)
- GPCR19(32 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(181 products)
- Hedgehog/Smoothened(46 products)
- Histamine Receptor(380 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(309 products)
- PAFR(12 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5696 products of "GPCR/G-Protein"
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Eprazinone dihydrochloride
CAS:<p>Eprazinone dihydrochloride (NSC 317935) is a mucolytic with antitussive and mucolytic effect.</p>Formula:C24H32N2O2·2HClPurity:99.25%Color and Shape:A White Or Almost White CrysMolecular weight:453.44Desipramine
CAS:<p>Desipramine: tricyclic antidepressant that blocks norepinephrine reuptake and helps reduce sleep-related pharyngeal collapsibility.</p>Formula:C18H22N2Color and Shape:SolidMolecular weight:266.38Azaperone
CAS:Azaperone, a sedative and antiemetic veterinary tranquilizer, belongs to pyridinylpiperazine and butyrophenone classes.Formula:C19H22FN3OPurity:98.73%Color and Shape:White Or Off-White CrystallineMolecular weight:327.4Facinicline (free base)
CAS:Facinicline (free base) is a partial agonist of the nicotinic alpha-7 (α7) receptor. It is used for the oral treatment of Alzheimer's.Formula:C15H18N4OColor and Shape:SolidMolecular weight:270.33H4 Receptor antagonist 1
CAS:H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.Formula:C16H17ClN4OPurity:98.81%Color and Shape:SolidMolecular weight:316.79Istradefylline
CAS:<p>Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails.</p>Formula:C20H24N4O4Purity:98.18% - 99.95%Color and Shape:SolidMolecular weight:384.43Melanin Concentrating Hormone, salmon acetate
Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.Formula:C91H143N27O26S4Purity:99.41%Color and Shape:SolidMolecular weight:2157SB 204741
CAS:SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.Formula:C14H14N4OSPurity:99.83%Color and Shape:SolidMolecular weight:286.35CYM-5520
CAS:<p>CYM-5520 is a noncompetitive allosteric agonist of S1P2</p>Formula:C21H19N3O2Purity:99.47%Color and Shape:SolidMolecular weight:345.39Rizatriptan benzoate
CAS:<p>Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine</p>Formula:C22H25N5O2Purity:99% - 99.79%Color and Shape:White To Off-White Crystalline PowderMolecular weight:391.47Irdabisant hydrochloride
CAS:<p>Irdabisant (CEP-26401) is a selective H3R inverse agonist, BBB-penetrable, with cognition-enhancing effects.</p>Formula:C18H24ClN3O2Color and Shape:SolidMolecular weight:349.86Geissoschizine methyl ether
CAS:Geissoschizine methyl ether: an alkaloid from Uncaria hook, key in Yokukansan, impacts mood and social behavior enhancing serotonin activity.Formula:C22H26N2O3Purity:99.24% - 99.68%Color and Shape:SolidMolecular weight:366.45ML417
CAS:ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).Formula:C22H25N3O3Purity:98.4% - 99.42%Color and Shape:SolidMolecular weight:379.45ML-178
CAS:ML-178: selective S1PR4 agonist, EC50 of 46 nM; inactive on other S1P receptors at 25 μM.Formula:C13H9Br2Cl2NO2Purity:95.92%Color and Shape:SolidMolecular weight:441.93SB756050
CAS:<p>SB756050 is a specific TGR5 agonist.</p>Formula:C21H28N2O8S2Purity:98.78% - >99.99%Color and Shape:SolidMolecular weight:500.59Piboserod
CAS:<p>Piboserod (SB-207266) (SB 207266) is a selective 5-HT(4) receptor antagonist.</p>Formula:C22H31N3O2Purity:97.21% - 99.49%Color and Shape:SolidMolecular weight:369.5CAY10444
CAS:<p>CAY10444 is an S1P3 specific antagonist.</p>Formula:C15H29NO2SPurity:99.15% - 99.61%Color and Shape:SolidMolecular weight:287.46MIPS521
CAS:MIPS521 ({2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiophen-3-yl}(4-chlorophenyl)methanone) is a positive allosteric modulator of the A1R.Formula:C19H10ClF6NOSPurity:99.76%Color and Shape:SolidMolecular weight:449.8L-745870 trihydrochloride
CAS:<p>L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.</p>Formula:C18H22Cl4N4Purity:97.52%Color and Shape:SolidMolecular weight:436.21PU02
CAS:<p>PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.</p>Formula:C16H12N4SPurity:99.35%Color and Shape:SolidMolecular weight:292.36Prucalopride Succinate
CAS:Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).Formula:C18H26ClN3O3·C4H6O4Purity:99.24%Color and Shape:SolidMolecular weight:485.96K 41498 aceate
K41498 acetate, a potent CRF2 antagonist (Ki: 0.66/0.62 nM for CRF2α/β) with 425 nM for CRF1; blocks aSvg-30 effect on cAMP in cells.Purity:96.4%Color and Shape:LiquidMolecular weight:N/ATolnapersine
CAS:<p>Tolnapersine is a mixed dopamine agonist and alpha-adrenoceptor antagonist.</p>Formula:C21H26N2OPurity:98%Color and Shape:SolidMolecular weight:322.44Nemifitide acetate(173240-15-8 free base)
<p>Nemifitide acetate, synthetic 5-amino acid antidepressant, has quick effect, mimics MIF.</p>Formula:C35H47FN10O8Purity:97.97%Color and Shape:SolidMolecular weight:754.85Selexipag
CAS:<p>Selexipag (ACT-293987, NS-304) is a drug for PAH that dilates pulmonary vessels.</p>Formula:C26H32N4O4SPurity:99.98% - >99.99%Color and Shape:SolidMolecular weight:496.62Pizuglanstat
CAS:<p>Pizuglanstat is a hematopoietic prostaglandin synthase inhibitor.</p>Formula:C27H36N6O4Purity:99.62%Color and Shape:SolidMolecular weight:508.61Etelcalcetide hydrochloride
CAS:<p>Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.</p>Formula:C38H73N21O10S2HClPurity:>99.99%Color and Shape:SolidMolecular weight:1353.33Zatebradine
CAS:<p>Zatebradine is a potent hyperpolarization-activated cyclic nucleotide-gated (HCN) channels inhibitor(IC50 of 1.96 μM).</p>Formula:C26H36N2O5Purity:98%Color and Shape:SolidMolecular weight:456.57Mini Gastrin I, human acetate
<p>Mini Gastrin I, human acetate is a shorter version of human gastrin, consists of amino acids 5-17 of the parent peptide.</p>Formula:C76H103N15O28SPurity:99.35% - 99.82%Color and Shape:SolidMolecular weight:1706.78Procaterol hydrochloride hydrate
CAS:Short-acting β2-adrenergic receptor agonist used to treat asthma.Formula:C32H48Cl2N4O7Purity:99.71% - 99.97%Color and Shape:SolidMolecular weight:671.65Naratriptan
CAS:<p>Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches.</p>Formula:C17H25N3O2SPurity:99.08%Color and Shape:SolidMolecular weight:335.47Carazolol
CAS:Carazolol (Suacron) is a high-affinity antagonist/partial inverse agonist (also referred to as a beta blocker) of the β-adrenergic receptor.Formula:C18H22N2O2Purity:99% - 99.53%Color and Shape:Yellowish SolidMolecular weight:298.38Human growth hormone-releasing factor acetate
Human growth hormone-releasing factor acetate is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) onPurity:99.26%Color and Shape:LiquidMolecular weight:N/ARaclopride
CAS:Raclopride is a selective antagonist of dopamine D2/D3 receptor.Formula:C15H20Cl2N2O3Purity:99.17%Color and Shape:SolidMolecular weight:347.24Neurotensin(8-13) 3TFA(60482-95-3(free base))
CAS:Neurotensin(8-13) 3TFA is Neurotensin (NT) fragment. Neurotensin(8-13) 3TFA results in a decrease in cell-surface NT1 receptors (NTR1) density.Formula:C40H65F3N12O10Purity:98.31%Color and Shape:SolidMolecular weight:931.03SCH 58261
CAS:SCH 58261 is a potent and selective A2a adenosine receptor antagonist.The Ki =2.3 nM for rat A2a and 2 nM is for bovine A2a.Formula:C18H15N7OPurity:99.07% - 99.75%Color and Shape:SolidMolecular weight:345.36Mosapride
CAS:Mosapride (AS-4370) is a selective 5HT4 agonistFormula:C21H25ClFN3O3Purity:99.56%Color and Shape:White To Off-White Crystalline SolidMolecular weight:421.89ACEPROMAZINE MALEATE
CAS:ACEPROMAZINE MALEATE is a dopamine receptor antagonistFormula:C23H26N2O5SPurity:98.87% - 99.51%Color and Shape:Off White Or Yellow Crystalline PowderMolecular weight:442.53Betahistine dihydrochloride
CAS:Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator.Formula:C8H14Cl2N2Purity:99.22% - 99.88%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:209.12Lecirelin acetate(61012-19-9 free base)
<p>Lecirelin acetate is a synthetic GnRH (gonadotropin releasing hormone) analogue which shows a great efficacy in the treatment of bovine ovarian follicular cysts</p>Formula:C61H88N16O14Purity:98.1%Color and Shape:SolidMolecular weight:1269.45Perospirone
CAS:<p>Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors.</p>Formula:C23H30N4O2SPurity:99.23%Color and Shape:White PowderMolecular weight:426.57DAPTA
CAS:DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.Formula:C35H56N10O15Purity:>99.99%Color and Shape:SolidMolecular weight:856.88Neurokinin A(4-10) TFA(97559-35-8 free base)
Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].Formula:C36H55F3N8O12SPurity:>99.99%Color and Shape:SolidMolecular weight:880.93RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purity:98.64% - 99.62%Color and Shape:SolidMolecular weight:417.5Idazoxan hydrochloride
CAS:<p>Idazoxan hydrochloride (RX 781094) is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity.</p>Formula:C11H12N2O2·HClPurity:99.42% - 99.84%Color and Shape:SolidMolecular weight:240.69BAR 501 impurity
CAS:<p>BAR 501 impurity 在 BAR501 制剂中发现的一种杂质，可作为 G 蛋白偶联胆汁酸激活受体 (GP-BAR1) 的激动剂。 BAR501 杂质 (10 µM) 在 GP-BAR1 报告基因检测中诱导荧光素酶活性增加 150%。</p>Formula:C26H46O3Purity:98.78%Color and Shape:SolidMolecular weight:406.64Dimaprit dihydrochloride
CAS:<p>Dimaprit dihydrochloride: selective H2 agonist, inhibits nNOS (IC50: 49 μM), boosts gastric acid.</p>Formula:C6H15N3S·2HClPurity:99.79%Color and Shape:SolidMolecular weight:234.19Chlorphenesin
CAS:<p>Chlorphenesin (Chlorophenesin) is an antigen-associated immunosuppressant that inhibits IgE-mediated histamine release. It is also used as an antimycotic agent.</p>Formula:C9H11ClO3Purity:99.59%Color and Shape:SolidMolecular weight:202.63BD1063 dhydrochloride
CAS:BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).Formula:C13H20Cl4N2Purity:99.52% - ≥95%Color and Shape:SolidMolecular weight:346.12Tolazoline
CAS:<p>Tolazoline (Benzalolin), a vasodilator, treats vessel spasms and reverses 5-HT2A drug overdose effects.</p>Formula:C10H12N2Purity:99.52%Color and Shape:SolidMolecular weight:160.22
