GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(993 products)
- Adenosine Receptor(246 products)
- Adrenergic Receptor(3,004 products)
- Bombesin Receptor(33 products)
- Bradykinin Receptor(59 products)
- CXCR(153 products)
- CaSR(33 products)
- Cannabinoid Receptor(212 products)
- Dopamine Receptor(433 products)
- Endothelin Receptor(79 products)
- GNRH Receptor(77 products)
- GPCR19(32 products)
- GRK(32 products)
- GTPase(22 products)
- Glucagon Receptor(182 products)
- Hedgehog/Smoothened(47 products)
- Histamine Receptor(381 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(310 products)
- PAFR(12 products)
- PKA(51 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5745 products of "GPCR/G-Protein"
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Tripelennamine citrate
CAS:Tripelennamine citrate, an ethylenediamine derivative, blocks H1 receptors to treat allergies and anaphylaxis.Formula:C22H29N3O7Color and Shape:SolidMolecular weight:447.488Triprolidine hydrochloride
CAS:Triprolidine hydrochloride anhydrous, a Histamine H1 antagonist, is used in asthma, allergic rhinitis, and urticaria.Formula:C19H23ClN2Color and Shape:SolidMolecular weight:314.852RS 100329
CAS:RS 100329 HCl is a selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors).Formula:C20H25F3N4O3Color and Shape:SolidMolecular weight:426.43Triprolidine
CAS:Triprolidine: oral H1 receptor blocker with motor/sensory spinal effects, for allergy research.Formula:C19H22N2Color and Shape:SolidMolecular weight:278.39CYM-5541
CAS:<p>CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist.</p>Formula:C19H28N2O2Purity:99.74% - 99.76%Color and Shape:SolidMolecular weight:316.44Flibanserin hydrochloride
CAS:<p>Flibanserin HCl: oral 5-HT1A agonist & 5-HT2A antagonist, Ki values 1 nM & 49 nM, for HSDD, has antidepressant/anxiolytic properties.</p>Formula:C20H22ClF3N4OColor and Shape:SolidMolecular weight:426.87Tesmilifene fumarate
CAS:Tesmilifene fumarate (DPPE fumarate) (DPPE fumarate) is an H1C receptor antagonist。Formula:C23H29NO5Purity:99.86%Color and Shape:SolidMolecular weight:399.48Dolasetron
CAS:<p>Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.</p>Formula:C19H20N2O3Purity:99.84% - 99.86%Color and Shape:White PowderMolecular weight:324.37Netupitant
CAS:Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).Formula:C30H32F6N4OPurity:99.43%Color and Shape:SolidMolecular weight:578.59PAR-2 Activating Peptide acetate
<p>PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate) is an agonist of Protease-Activated Receptor-2 (PAR-2).</p>Formula:C31H60N10O9Purity:98.5% - 99.92%Color and Shape:SolidMolecular weight:716.88Pimavanserin tartrate
CAS:<p>Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist used to treat Parkinson's disease-related psychosis.Cost-effective and quality-assured.</p>Formula:C50H68F2N6O4·C4H6O6Purity:99.24% - 99.98%Color and Shape:SolidMolecular weight:1005.2Ocaperidone
CAS:Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.Formula:C24H25FN4O2Purity:99.33%Color and Shape:SolidMolecular weight:420.48Namodenoson
CAS:<p>Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.</p>Formula:C18H18ClIN6O4Purity:98.97%Color and Shape:SolidMolecular weight:544.73Mozavaptan
CAS:<p>Mozavaptan (OPC-31260) is a competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively.</p>Formula:C27H29N3O2Purity:98.98% - 99.12%Color and Shape:SolidMolecular weight:427.54Pardoprunox hydrochloride
CAS:Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1)Formula:C12H16ClN3O2Purity:98.95% - 99.13%Color and Shape:SolidMolecular weight:269.73JNJ-10229570
CAS:<p>JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland</p>Formula:C22H19N3O2SPurity:98.41%Color and Shape:SolidMolecular weight:389.47NGB 2904
CAS:NGB 2904 is a potent and selective antagonist of dopamine D3 receptor. NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).Formula:C28H29Cl2N3OPurity:98.79%Color and Shape:SolidMolecular weight:494.46ML401
CAS:ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .Formula:C20H20BrClN2OPurity:99.13%Color and Shape:SolidMolecular weight:419.74Vericiguat
CAS:<p>Vericiguat (BAY1021189) is a potent and orally available guanylate cyclase stimulator.</p>Formula:C19H16F2N8O2Purity:98.86% - 99.93%Color and Shape:SolidMolecular weight:426.38Rotigotine Hydrochloride
CAS:<p>Rotigotine HCl, D3-preferential dopamine agonist, is 50x stronger than quinpirole in anti-Parkinson's efficacy.</p>Formula:C19H26ClNOSPurity:99.53% - 99.56%Color and Shape:Almost White To White Crystalline PowderMolecular weight:351.93DPCPX
CAS:DPCPX (PD 116948) is an A1 adenosine receptor antagonistFormula:C16H24N4O2Purity:99.23% - 99.93%Color and Shape:White SolidMolecular weight:304.39MK 212 hydrochloride
CAS:MK 212 hydrochloride is a 5-HT2C receptor agonistFormula:C8H11ClN4·HClPurity:99.88%Color and Shape:SolidMolecular weight:235.12Donitriptan Mesylate
CAS:Donitriptan Mesylate, a 5-HT1B/1D agonist, is used potentially for the treatment of migraines.Formula:C24H29N5O5SColor and Shape:SolidMolecular weight:499.58Tirzepatide Acetate(2023788-19-2 free base)
Tirzepatide (LY3298176) Acetate (2023788-19-2 free base) is a new molecule that can control blood glucose levels.Cost-effective and quality-assured.Formula:C227H352N48O70Purity:97.3% - 98.05%Color and Shape:SolidMolecular weight:4873.5Fipamezole HCl
CAS:Fipamezole HCl, a α2-adrenoceptor antagonist, is used potentially for the treatment of dyskinesia associated with Parkinson's disease.Formula:C14H16ClFN2Color and Shape:SolidMolecular weight:266.74Abaperidone Hydrochloride
CAS:<p>Abaperidone Hydrochloride is an atypical antipsychotic, potently binging to5-HT2 receptors and D2 receptors.</p>Formula:C25H26ClFN2O5Color and Shape:SolidMolecular weight:488.94Fabomotizole
CAS:Fabomotizole (Obenoxazine) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.Formula:C15H21N3O2SPurity:99.4%Color and Shape:SolidMolecular weight:307.41Parethoxycaine hydrochloride
CAS:<p>Parethoxycaine hydrochloride (2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride) is an anesthetic[1].</p>Formula:C15H24ClNO3Purity:99.46%Color and Shape:SolidMolecular weight:301.81ARN272
CAS:ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).Formula:C27H20N4O2Purity:98.23%Color and Shape:SolidMolecular weight:432.47Reboxetine
CAS:Reboxetine (Norebox) is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD.Formula:C19H23NO3Purity:98%Color and Shape:SolidMolecular weight:313.39Acitazanolast
CAS:<p>Acitazanolast (WP-871) is an anti-allergic drug candidate.</p>Formula:C9H7N5O3Purity:98.25%Color and Shape:SolidMolecular weight:233.18Neuropeptide W-23(human)
CAS:Neuropeptide W-23(human) (NPW-23) is an endogenous ligand for NPBW1 and NPBW2.Formula:C119H183N35O28SPurity:98.5%Color and Shape:SolidMolecular weight:2584.01Gastrin I (1-14), human
CAS:Gastrin I (1-14), human: a short peptide from the hormone gastrin, which regulates gastric acid secretion.Formula:C79H100N16O27Purity:98.19%Color and Shape:SolidMolecular weight:1705.73cicloprofen
CAS:<p>cicloprofen is Cell division cycle 7-related protein kinase (human) inhibitor.</p>Formula:C16H14O2Purity:98.15%Color and Shape:SolidMolecular weight:238.2812Melperone
CAS:<p>Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.</p>Formula:C16H22FNOPurity:98.84%Color and Shape:SolidMolecular weight:263.35Lanreotide acetate
CAS:Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndromeFormula:C56H73N11O12S2Purity:>99.99%Color and Shape:SolidMolecular weight:1156.39RS-127445 hydrochloride
CAS:<p>RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).</p>Formula:C17H17ClFN3Purity:99.48%Color and Shape:SolidMolecular weight:317.79ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139BD 1008 Free Base
CAS:BD 1008 Free Base: Sigma-1 receptor antagonist, Kᵢ = 2 ± 1 nM, 4x more selective for sigma-1 than sigma-2.Formula:C15H22Cl2N2Color and Shape:SolidMolecular weight:301.25Sonepiprazole hydrochloride
CAS:Sonepiprazole HCl is a a selective dopamine D4 antagonist.Formula:C21H28ClN3O3SColor and Shape:SolidMolecular weight:437.98Carmoxirole (free base)
CAS:Carmoxirole: a dopamine D2 agonist, reduces pre-load/afterload, aids heart failure, lowers blood pressure by inhibiting noradrenaline release.Formula:C24H26N2O2Color and Shape:SolidMolecular weight:374.48SB-203186 hydrochloride
CAS:<p>SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist</p>Formula:C16H20N2O2·HClPurity:99.64%Color and Shape:SolidMolecular weight:308.81Zacopride
CAS:Zacopride is a selective agonist of inward rectifier potassium current (I K1) channel, inhibiting ventricular arrhythmias without affecting atrial arrhythmias.Formula:C15H20ClN3O2Purity:98%Color and Shape:SolidMolecular weight:309.79DSP 4
CAS:DSP 4: neurotoxin targeting locus coeruleus, crosses blood-brain barrier, forms aziridinium, enters nerves via noradrenaline transporter.Formula:C11H15BrClNColor and Shape:SolidMolecular weight:276.6Bindarit
CAS:<p>Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.</p>Formula:C19H20N2O3Purity:98.35% - 98.55%Color and Shape:SolidMolecular weight:324.37Evatanepag sodium
CAS:Evatanepag (CP-533536), an EP2-specific PGE2 agonist, promotes bone growth and heals fractures in rats with a single dose.Formula:C25H27N2NaO5SColor and Shape:SolidMolecular weight:490.55Haloperidol lactate
CAS:Haloperidol lactate: a potent antipsychotic for acute/chronic schizophrenia and polyarousal syndrome research.Formula:C24H29ClFNO5Color and Shape:SolidMolecular weight:465.95Moxisylyte
CAS:Moxisylyte (thymoxamine) treats erectile dysfunction, Reynaud's syndrome, and reverses eye mydriasis; it's an α1-adrenergic blocker.Formula:C16H25NO3Color and Shape:SolidMolecular weight:279.37Hydroxyzine
CAS:<p>Hydroxyzine (Hydroxyzine free base) is an antagonist of histamine H1-receptor.</p>Formula:C21H27ClN2O2Purity:99.54% - ≥95%Color and Shape:Oil SolidMolecular weight:374.9GUANABENZ
CAS:<p>GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.</p>Formula:C8H8Cl2N4Purity:98.31%Color and Shape:White Solid From Acetonitrile SolidMolecular weight:231.08
