GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,024 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,029 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(441 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(83 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(326 products)
- PAFR(13 products)
- PKA(51 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5965 products of "GPCR/G-Protein"
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AZD-4818
CAS:AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C27H32Cl2N2O7Purity:99.01%Color and Shape:SolidMolecular weight:567.46BX471
CAS:<p>BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.</p>Formula:C21H24ClFN4O3Purity:98% - 99.94%Color and Shape:SolidMolecular weight:434.89Glasdegib
CAS:Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.Formula:C21H22N6OPurity:98.72%Color and Shape:SolidMolecular weight:374.44Maraviroc
CAS:Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.Formula:C29H41F2N5OPurity:97.13% - 99.59%Color and Shape:Brown SolidMolecular weight:513.67Cenicriviroc
CAS:Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.Formula:C41H52N4O4SPurity:97.87%Color and Shape:SolidMolecular weight:696.94RS102895
CAS:<p>RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.</p>Formula:C21H21F3N2O2Purity:97.64% - 99.80%Color and Shape:SolidMolecular weight:390.4Vercirnon
CAS:<p>Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.</p>Formula:C22H21ClN2O4SPurity:99.23%Color and Shape:SolidMolecular weight:444.93SAG hydrochloride (912545-86-9(free base))
CAS:SAG hydrochloride (912545-86-9(free base)) (Smoothened Agonist HCl) acts as an SMO agonist.Formula:C28H29Cl2N3OSPurity:99.19% - 99.97%Color and Shape:SolidMolecular weight:526.52R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Formula:C21H27NO4Purity:99.03%Color and Shape:SolidMolecular weight:357.44Sonidegib
CAS:Sonidegib (Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.Formula:C26H26F3N3O3Purity:98% - 99.97%Color and Shape:SolidMolecular weight:485.5Salmeterol Xinafoate
CAS:<p>Salmeterol Xinafoate (GR 33343X xinafoate) is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma.</p>Formula:C36H45NO7Purity:98% - 98.24%Color and Shape:White SolidMolecular weight:603.75MRT-81
CAS:MRT-81 blocks Smo receptors in Shh-light2 cells at 41 nM IC50, showing strong hedgehog pathway inhibition, useful in cancer research.Formula:C31H29N3O5SPurity:99.72%Color and Shape:SolidMolecular weight:555.64SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Formula:C18H18N2O5Purity:99.59%Color and Shape:SolidMolecular weight:342.35Treprostinil
CAS:<p>Treprostinil (Orenitram) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM).</p>Formula:C23H34O5Purity:99.29%Color and Shape:SolidMolecular weight:390.51Binodenoson
CAS:Binodenoson (WRC 0470), a selective A2A adenosine receptor agonist, aids in coronary imaging.Formula:C17H25N7O4Purity:99.74%Color and Shape:SolidMolecular weight:391.42Nelotanserin
CAS:Nelotanserin (APD125): strong 5-HT2A inverse agonist (IC50: 1.7 nM), moderate 5-HT2C (79 nM), weak 5-HT2B (791 nM).Formula:C18H15BrF2N4O2Purity:98.42% - 99.88%Color and Shape:SolidMolecular weight:437.24Asapiprant
CAS:Asapiprant (S-555739) is a potent and selective DP1 receptor antagonist (Ki: 0.44 nM). It exhibited high affinity and selectivity for the DP1 receptor.Formula:C24H27N3O7SPurity:99.64%Color and Shape:SolidMolecular weight:501.55Nelociguat
CAS:<p>Nelociguat (BAY60-4552) is an sGC stimulator, crucial in NO signal pathways.</p>Formula:C19H17FN8O2Purity:99.19%Color and Shape:SolidMolecular weight:408.39Neurokinin A
CAS:Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene.Formula:C50H80N14O14SPurity:>99.99%Color and Shape:White To Off-White Lyophilized SolidMolecular weight:1133.32Ticagrelor metabolite M5
CAS:Ticagrelor metabolite M5 (T437700) is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor.Formula:C14H22N6O4SPurity:99.35%Color and Shape:SolidMolecular weight:370.43
