GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,018 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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TRV045
CAS:TRV045 is a selective agonist of the sphingosine-1-phosphate (S1P) subtype 1 receptor and does not impact lymphocyte trafficking. It possesses antiepileptic properties.Formula:C18H18N4O3Color and Shape:SolidMolecular weight:338.36[Nle11]-Substance P
CAS:'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'
Formula:C64H100N18O13Purity:98%Color and Shape:SolidMolecular weight:1329.59Hemokinin 1, human TFA
Hemokinin-1 is a human TFA and selective NK1 agonist; also activates NK2 & NK3 and induces opioid-independent analgesia.Formula:C56H85F3N14O16SColor and Shape:SolidMolecular weight:1299.42Endothelin-2 (49-69), human TFA
Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.Formula:C117H161N26F3O34S4Purity:98%Color and Shape:SolidMolecular weight:2660.94LY 344864 racemate
CAS:LY 344864 racemate is a 5-HT1F receptor agonist.Formula:C21H22FN3OPurity:99.75%Color and Shape:SoildMolecular weight:351.428-iso-15-keto Prostaglandin F2α
CAS:8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.471HPP-9
HPP-9, a Proteolysis-Targeting Chimera (PROTAC) derived from Hedgehog Pathway Inhibitor-1 (HPI-1) with a pIC50 value of 6.71, is designed to degrade BETFormula:C49H52N6O11Color and Shape:SolidMolecular weight:900.97Tamuzimod
CAS:Tamuzimod, an effective immunomodulator, exhibits modulatory activity on S1P Receptors with EC50 values below 1 μM [1] [2].Formula:C21H13Cl3F3N5O3Color and Shape:SolidMolecular weight:546.71SAE-14
CAS:GPR183, a chemotactic receptor aiding B cell maturation, binds 7α,25-OHC; studied in IBD research.Formula:C19H19F3N2O2Purity:99.85%Color and Shape:SolidMolecular weight:364.36Ro60-0175
CAS:Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.Formula:C11H12ClFN2Purity:97.09%Color and Shape:SolidMolecular weight:226.68Ref: TM-T39161
1mg93.00€5mg205.00€10mg334.00€25mg587.00€50mg802.00€100mg1,108.00€1mL*10mM (DMSO)187.00€PAR 4 (1-6)
CAS:PAR 4 (1-6) can be used for relevant research in the life sciences. Its product number is T36293 and CAS number is 225779-44-2.Formula:C28H41N7O9Color and Shape:SolidMolecular weight:619.676GLP-1R agonist 4
CAS:GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.Formula:C32H30ClF2N3O5Color and Shape:SolidMolecular weight:610.05Pellotine
CAS:Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formula:C13H19NO3Color and Shape:SolidMolecular weight:237.295Upacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Formula:C11H15Cl2N3O6SPurity:98.56%Color and Shape:SoildMolecular weight:388.22Paynantheine
CAS:Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.Formula:C23H28N2O4Color and Shape:SolidMolecular weight:396.48Piperulin A
CAS:Piperulin A effectively inhibits platelet-activating factor receptor (PAFR) by specifically blocking its binding to isolated rabbit platelet plasma membranes,Formula:C23H28O6Color and Shape:SolidMolecular weight:400.46M871
CAS:GAL2 receptor antagonist; Ki: 13.1 nM (GAL2), 420 nM (GAL1); inhibits GAL2-induced pain.Formula:C108H163N27O28Purity:98%Color and Shape:SolidMolecular weight:2287.64RC-3095
CAS:RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.Formula:C56H79N15O9Purity:98%Color and Shape:SolidMolecular weight:1106.32EP4 receptor antagonist 3
CAS:EP4 receptor antagonist 3 from patent WO2010019796 A1 targets EP4 for research on pain, arthritis, and cancer.Formula:C26H21F3N2O3SColor and Shape:SolidMolecular weight:498.52Lenbelintide
CAS:Lenbelintide is a dual amylin/calcitonin receptor agonist, useful in studies related to obesity.Color and Shape:Solid
![[Nle11]-Substance P](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1831.webp&w=3840&q=75)
