GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,018 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(194 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5983 products of "GPCR/G-Protein"
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NPC 567
CAS:NPC 567 is an antagonist of the bradykinin receptor.Formula:C60H87N19O13Purity:98%Color and Shape:SolidMolecular weight:1282.48Neuropeptide S(Mouse) TFA
Neuropeptide S(Mouse) TFA: Endogenous NPSR agonist, EC50 3 nM, boosts Ca2+, activity, wakefulness, and lowers mouse anxiety.
Formula:C92H157F3N34O29Color and Shape:SolidMolecular weight:2296.49PAR-2 (1-6) (human)
CAS:PAR-2 (1-6) (human) (SLIGKV), a peptide ligand, is a PAR-2 agonist [1] .Formula:C28H53N7O8Color and Shape:SolidMolecular weight:615.76Pindolol
CAS:Pindolol is an effective, non-selective, and specific beta-receptor blocker that acts as a partial beta-adrenergic receptor agonist and a localized 5-HT1A receptor antagonist (Ki=33nM). Pindolol has intrinsic sympathetic activity (ISA) and is primarily used to treat high blood pressure and certain heart conditions. Exhaustion.Formula:C14H20N2O2Color and Shape:Crystals From Ethanol SolidMolecular weight:248.32Urodilatin
CAS:Urodilatin, an analogue of ANF-(99-126), serves as a diuretic-natriuretic regulatory peptide with applications in the study of acute renal failure, congestiveColor and Shape:SolidMRS 2957 triethylammonium salt
CAS:MRS 2957 triethylammonium salt is a P2Y6 agonist.Formula:C19H28N5O20P3Purity:98%Color and Shape:SolidMolecular weight:739.37[Nle11]-Substance P
CAS:'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'
Formula:C64H100N18O13Purity:98%Color and Shape:SolidMolecular weight:1329.59LP 12 hydrochloride
CAS:LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).Formula:C32H40ClN3OColor and Shape:SolidMolecular weight:518.14Kisspeptin-10, rat TFA
Kisspeptin-10, a rat TFA, constricts blood vessels, inhibits vessel growth, and counters Methotrexate reproductive toxicity.Formula:C65H84F3N17O17Color and Shape:SolidMolecular weight:1432.46M871
CAS:GAL2 receptor antagonist; Ki: 13.1 nM (GAL2), 420 nM (GAL1); inhibits GAL2-induced pain.Formula:C108H163N27O28Purity:98%Color and Shape:SolidMolecular weight:2287.64Prostaglandin F1α
CAS:Prostaglandin F1α (PGF1α) is a lipid mediator and an endogenous metabolite of prostacyclin, regulate smooth muscle contraction.Formula:C20H36O5Color and Shape:SolidMolecular weight:356.5JNJ-10181457 (hydrochloride)
CAS:JNJ-10181457 (hydrochloride) is a non-imidazole H3 receptor antagonist that is brain-penetrating and selective, increasing NE and acetylcholine concentrationsFormula:C20H30Cl2N2OColor and Shape:SolidMolecular weight:385.37Guanylin(human) TFA
Guanylin (human) TFA, a 15-amino acid peptide, activates intestinal guanylate cyclase, regulating electrolyte and water transport via cGMP.Color and Shape:LiquidALD1613
ALD1613 is a potent neutralizing monoclonal antibody targeting adrenocorticotropic hormone (ACTH). It neutralizes ACTH-induced signaling and inhibits cyclic adenosine monophosphate accumulation in ACTH-stimulated Y1 (mouse adrenal cell line) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats and is applicable in studies involving elevated ACTH-related conditions.Color and Shape:Odour Liquid(Phe2,Orn8)-Oxytocin
CAS:(Phe2,Orn8)-Oxytocin: Selective V1 agonist, induces rabbit epididymis contractility, EC50=280 nM.Formula:C42H65N13O11S2Color and Shape:SolidMolecular weight:992.18AC 187 TFA
AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM.Formula:C129H206F3N37O42Color and Shape:SolidMolecular weight:3004.27Neurokinin B
CAS:NKB, a tachykinin peptide, impacts human functions like gonadotropin-releasing hormone secretion.Formula:C55H79N13O14S2Purity:98%Color and Shape:SolidMolecular weight:1210.425-HT2A receptor agonist-5
CAS:5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.Formula:C23H29N3OColor and Shape:SolidMolecular weight:363.58-iso-15-keto Prostaglandin F2α
CAS:8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans.Formula:C20H32O5Color and Shape:SolidMolecular weight:352.471Orforglipron hemicalcium hydrate
CAS:Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) represents the hemicalcium hydrate form of the calcium salt of Orforglipron, an orally active agonist targeting the Glucagon-like peptide-1 receptor (GLP-1R). This compound has demonstrated efficacy in mitigating type 2 diabetes [1].Formula:C48H48F2N10O5Ca·H2OColor and Shape:SolidMolecular weight:921.02
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