Acids and Synthetic Reagents

<p>Applications 11α-Hydroxy Canrenone is the key intermediate in the synthesis of Eplerenone, a cardiovascular drug. Canrenone was biotransformed into 11α-Hydroxycanrenone by Aspergillus ochraceus SIT34205.<br>References Luetscher, J., et al.: J. Clin. Invest., 29, 1576 (1950), Gaunt, R., et al.: J. Clin. Endocrinol. Metab., 15, 621 (1955), McMahon, E., et al.: Curr. Opin. Pharm., 1, 190 (2001), McMahon, E., et al.: Curr. Pharm. Des., 9, 1065 (2003),<br></p>

<p>Applications Tin(II) Acetate is used in stannous oral care compositions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Surerus, K., et al.: Biochemistry, 1994, 33, 4980 (1994),<br></p>

<p>Applications A fungal metabolite which is a potent inhibitor of HMG-CoA reductase.<br>References Endo, A., et al.: FEBS Letters, 72, 323 (1976), Endo, A.: J. Med. Chem., 28, 401 (1985)<br></p>

<p>Stability Hygroscopic<br>Applications Specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Richardson, B.P., et al.: Nature, 316, 126 (1985), Williams, F.M., et al.: J. Cardiovasc. Pharmacol., 7, 550 (1985), Waeber, C., et al.: Neuroscience, 31, 393 (1989), Seynaeve, C., et al.: Anti-Cancer Drugs, 2, 343 (1991), Fischer, V., et al.: Dug Metab. Dispos., 20, 603 (1992),<br></p>

<p>Applications Deuterated Tolterodine (T535800), a muscarinic receptor antagonist. Used in the treatment of urinary incontinence.<br>References Nilvebrant, L., et al.: Life Sci., 60, 1129 (1997), Nilvebrant, L., et al.: Eur. J. Pharmacol., 327, 195 (1997), Brynne, N., et al.: Int. J. Clin. Pharmacol. Ther., 35, 287 (1997)<br></p>

<p>Stability Moisture and Temperature Sensitive<br>Applications An inhibitor of O-GlcNAcase, hexosaminidase A, and hexosaminidase B.<br>References Baji, H., et al,: Eur. J. Med. Chem., 30, 617 (1995), Vaaje-Kolstad, G., et al.: J. Biol. Chem., 279, 3612 (2004), Perreira, M., et al.: Bioorg. Med. Chem., 14, 837 (2006).<br></p>

<p>Applications The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. Potent Histone deacetylase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Claus, R., et al.: Oncogene, 22, 6489 (2003), Johnstone, R., et al.: Cancer Cell., 4, 13 (2003), Ying, J., et al.: Clin. Cancer Res., 11, 6442 (2005), Catley, L., et al.: Blood, 108, 3441 (2006), Steinberg, M., et al.: Clin. Ther., 29, 2289 (2007),<br></p>

<p>Applications p-Hydroxymesocarb is the urinary metabolite of Mesocarb (M225650), a CNS stimulant that acts as a dopamine reuptake inhibitor.<br>References Vahermo, M., et al.: Archiv. Der. Pharmazie., 342, 201 (2009); Pyo, H., et al.: J. Chromatograph. Biomed. App., 687, 261 (1996);<br></p>

<p>Stability Hygroscopic<br>Applications Dihydrogen Hexachloroplatinate Hexahydrate is a reactant used in the synthesis of platinum, carbon dot hybrid nanoparticles.<br>References Shin, H. et al.: ACS. Catal., 6, 3914 (2016);<br></p>

<p>Applications An inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. Potent selective serotonin reuptake inhibitor (SSRI).<br>References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001),<br></p>

<p>Stability Light Sensitive<br>Applications α-Methacrylic acid is used in chemistry as a stabilizing agent, forming a thin capping layer on the surface of nanoparticles. α-Methacrylic acid is also used as a surfactant, so that control is maintained during nanocrystal growth. α-Methacrylic acid is also used as a chelating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peng, W., et al.: J. Cryst. Growth, 279, 454 (2005); Qu, S., et al.: Appl. Phys. Lett., 80, 3605 (2002); Zhao, G., et al.: Phys. C: Supercond., 468, 2317 (2008)<br></p>

<p>Applications A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.<br>References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),<br></p>

<p>Applications Potassium Hydroxide is inorganic compound and strong base with many applications. It is used in the production of biodiesel. Potassium Hydroxide is also used in the manufacture of soaps.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nadarajan, R., Ismail, R.: J. Surfactants Deterg., 14, 463 (2011); Hajek, M., et al.: Fuel, 96, 85 (2012);<br></p>

<p>Applications (R)-(+)-α-Methylbenzylamine (cas# 3886-69-9) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications An aromatase inhibitor. Also blocks adrenal steroidogenesis.<br>References Santen, R.J. and Misbin, R.I.: Pharmacotherapy, 1, 95 (1981), Havlin, K.A. and Trump, D.L.: Cancer Threat. Res., 39, 83 (1988)<br></p>

<p>Applications Vasodilator, used in treatments for angina.<br>References Miyamoto, S., et al.: Toxicol. Mech. Method., 19, 477 (2009), Perez-Reyes, E., et al.: J. Pharmacol. Exper. Ther., 328, 621(2009), Isoherranen, N., et al.: Chem. Res. Toxicol., 22, 294 (2009),<br></p>

<p>Applications Dibutyltin(IV) Oxide is used in studies pertaining to discovering novel antitumor agents. Antifungal activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Boualam, M. et al.: App. Organometal. Chem., 6, 197 (1992); Hadi, S. et al.: Ori. J. Chem., 26, 775 (2010); Hadi, S. et al.: Modern. App. Sci., 3, 12 (2009);<br></p>

<p>Applications A selective ATP-competitive inhibitor of protein kinase CK2 from such divergent sources as yeast, rat liver, Neurospora erassa and Candida tropicalis, with Ki values in the range of 0.5-1uM. It is virtually inactive against PKA, PKC, and a very weak inhibitor of protein kinase CK1.<br>References Zien, P., et al.: Biochemical and Biophysical Res. Commun., 306, 129 (2003)<br></p>

<p>Applications Selenourea is an excellent antiradical agent and biomimetic catalysts of glutathione peroxidase for the scavenging of hydrogen peroxide. It is also potent and selective cytotoxic agent against cancer cells. Chalcogenizing agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marset, A., et al.: Future Med. Chem., 8, 2185-2195 (2016); Tulenin, S. S., et al.: Russ. J. Inorg. Chem., 61, 488-495 (2016)<br></p>

<p>Applications Tropolone is found in many natural compounds. It is an inhibitor of grape polyphenol oxidase (PPO).<br>References Nunez-Delicado, E., et al.: J. Agric. Food Chem., 53, 6087 (2005); Okumura, S., et al.: Food Sci Technol Res., 17, 251 (2011);<br></p>

<p>Applications BARIUM CARBONATE (cas# 513-77-9) is a useful research chemical.<br></p>

<p>Applications An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.<br>References Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984), Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984), Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995), Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002), Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004),<br></p>

<p>Applications CDDO Methyl Ester is a synthetic triterpenoid that inhibits IκBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer.<br>References Shishodia, S. et al.: Clin. Cancer Res., 12, 1828 (2006); Konopleva, M. et al.: Leukemia, 19, 1350 (2005); Deeb, D. et al.: Cancers, 2, 1779 (2010); Gao, X. et al.: J. Exp. Therap. Oncol., 9, 119 (2011);<br></p>

<p>Applications Sodium Triphosphate is used in method and device for preparing concrete board with adjustable light aggregate position.<br>References Zhong, B., et al.: Faming Zhuanli Shenqing, (2021);<br></p>

<p>Applications Ethyl Acetate is a chemical intermediate used in the production of various analgesics, antibiotics and antimalarial agents.<br>References Mutti, F.G., et al.: Adv. Syn. Cata., 354, 3409 (2012); Subudhi, B., et al.: Bull. Chem. Soc., Ethiopia., 26, 455 (2012);<br></p>

<p>Stability Moisture Sensitive<br>Applications 3-Glycidoxypropyltrimethoxysilane (cas# 2530-83-8) is a useful research chemical.<br></p>

<p>Applications Ammonium Persulfate is used as a reagent in the low temperature synthesis of carbon-encapsulated spherical Fe7S8 nanocrystals as high-performance anode for lithium-ion batteries.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, B., et al.: Mater. Chem. Phys., 151, 60 (2015)<br></p>

<p>Applications (±)-Rolipram is a cAMP-specific phosphodiesterase 4 (PDE4) inhibitor.<br>References Xin, W., et. al.: J. Pharmacol. Exp. Ther., 349, 56 (2014);<br></p>

<p>Applications (-)-Verbenone is used to study antioxidant activity of essential oil components in lipid model systems.<br>References Ruberto, G., et al.: Food Chem., 69, 167 (2000);<br></p>

<p>Applications L-Leucic Acid is a reagent in the synthesis of cryptophycins based macrocyclic depsipeptides which are used as tubulin inhibitors.<br>References Kumar, A., et al.: Eur. J. Med. Chem., 93, 55 (2015)<br></p>

<p>Applications A selective serotonin reuptake inhibitor. Used as an antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>

<p>Applications BENZAMIDINE (cas# 618-39-3) is a useful research chemical.<br></p>

<p>Applications Hexadecanedioic Acid is a useful research intermediate for the studies of blood pressure regulations in humans. Hexadecandedioate works in collaboration with SLCO1B1 as a potential therapy for statin.<br>References Menni, C., et al.: J. Hypertens., 34, 80 (2016)<br></p>

<p>Applications Pilsicainide is a Class IC drug, which induce the ST segment elevationin study with patients with Brugada syndrome.<br>References Fujiki, A., et al.: J. Cardiovasc. Electrophysiol., 10, 214 (1999); Ikeda, T., et al.: J. Cardiovasc. Electrophysiol., 17, 602 (2006);<br></p>

<p>Applications Foscarnet inhibits viral DNA polymerase and reverse transcriptase. Foscarnet is used as an antiviral.<br>References Helgstrand, E., et al.: Science, 201, 819 (1978), Reno, J.M., et al.: Antimicrob. Agents Chemother., 13, 188, (1978), Alenius, S., et al.: Arch. Virol., 60, 197 (1979),<br></p>

<p>Applications Peiminine is a derivative of Peimine (P218375) a steroidal alkaloid compound extracted from the Fritillaria species of medicinal plants.<br>References Zhou, J. et al.: J. Chrom. A., 1177, 126 (2008); Li, S. et al.: J. Chrom. A., 873, 221 (2000);<br></p>

<p>Applications Potassium Bisnonafluoro-1-butanesulfonimidate (cas# 129135-87-1) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Perindopril L-Arginine, is a complex compound of Perindopril (P287500), having the antihypertensive, cardiovascular protective and antithrombotic properties, and has been shown to exists as a neutral complex.<br>References Remko, M., et al.: Euro. J. Med. Chem., 44, 101 (2009); Morgan, T., et al.: J. Cardiovasc. Pharmacol., 10, Supp. 7, S116, (1987);<br></p>

<p>Applications Palladium(II) Acetylacetonate is an active anticancer agent. Exhibits growth inhibitory effect more than cisplatin in several cancer cells and treatment with Palladium(II) Acetylacetonate inhibits H460 cells. Palladium(II) Acetylacetonate is a catalyst for various organic transformations.<br>References Wang, Y., et al.: J. Med. Chem., 56, 9601 (2013); Fang, W., et al.: Small, 8, 3816 (2012); Yao, H., et al.: ACS Catalysis, 7, 5456 (2017)<br></p>

<p>Applications The S-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>

<p>Applications Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer's disease (AD).<br>References Portelius, E. et al.: Alzheim. Res. Ther., 22. No pp. given (2010); Imbimbo, B.P. et al.: Curr. Opin. Invest. Drugs, 10, 721 (2009); Panza, F. et al.: Curr. Med. Chem., 18, 5430 (2011);<br></p>

<p>Applications Magnesium Stearate is used in the synthesis of mini matrices for improved drug delivery.<br>References Sujja-areevath, J. et al.: Eur. J. Pharm. Sci., 6, 207 (1998); Sangalli, M. et al.: J. Control. Released., 73, 103 (2001);<br></p>

<p>Applications (-)-α-Kainic Acid Monohydrate is the monohydrated form of (-)-α-Kainic Acid (K135010); a naturally occurring neuroexcitatory chemical that is a selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus.<br>References Wacker, D.A., et al.: Synlett, 503 (1997); Dunleavy, M., et al.: J. Molec. Neurosci., 49, 202 (2013); Zhang, J., et al.: Neuron., 76, 1133 (2012); Yamada, J., et al.: Neurosci., 226, 119 (2012); Wang,Q., et al.: Mol. Neurobiol., 31, 3 (2005)<br></p>

<p>Stability Hygroscopic<br>Applications (-)-(18-Crown-6)-2,3,11,12-tetracarboxylic Acid is a chiral NMR solvating agent used for determining the enantiomeric purity and absolute configuration of β-amino acids. It is also used as a solvating agent in the chiral NMR discrimination of pyrrolidines.<br>References Wenzel, T.J., et al.: Tetrahedron-Assymetr., 20, 2052 (2009); Lovely, A.E., et al.: Chirality, 20, 370 (2008); Li, R., et al.: Fenxi Ceshi Xuebao, 26, 305 (2007); Lovely, A.E., et al.: Tetrahedron-Assymetr., 17, 2642 (2006)<br></p>

<p>Stability Hygroscopic<br>Applications A drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.<br>References Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008), Hoy, S., et al.: Drugs, 69, 1647 (2009), Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009),<br></p>

<p>Applications Dioctyloxotin, cna be used in various chemical synthesis such as in preparation of trinuclear seven-coordinated tin complexes, having possible antioxidant, and anti-inflammatory activity.<br>References Chans, G., et al.: Journal of Coordination Chemistry, Vol.68, P: 3741-3758 (2015);<br></p>

<p>Applications Calcium fluoride (cas# 7789-75-5) is a useful research chemical.<br></p>

<p>Applications (+)-MK 801 Hydrogen Maleate acts as an NMDA receptor antagonist. It is selective and potent, but noncompetitive, used in various ischemia treatments.<br>References Ma, J. et al.: Hippocamp., 22, 2208 (2012); Cao, Z. et al.: Toxicol. Sci., 130, 362 (2012);<br></p>

<p>Applications ABT 199 is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.<br>References Davids, M. &amp; Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013);<br></p>

<p>Stability Moisture Sensitive<br>Applications Tributylphenyltin acts as a reagent for the synthetic preparation of tetrahydroisoquinolines and SAR as potential HIV-1 antivirals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Swidorski, J. J., et al.: Bioorg. Med. Chem. Lett., 26, 160 (2016)<br></p>

<p>Applications An arginine-glycine-aspartate-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events.<br>References Pathak, A., et al.: Cardiovas. Diabetol., 7 (2008), Hantgan, R., et al.: Biochem., 48, 8355 (2009), Giugliano, R., et al.: New Eng. J. Med., 360, 2176 (2009),<br></p>

<p>Applications β-Formylpropionic Acid is used in the synthesis of potent and orally available nonpeptide antagonist of human gonadotropin-releasing hormone receptor. It is also a reagent in the synthesis of human melanocortin-4 receptor antagonists with a pyrrolidinone moiety.<br>References Chen, C. et al.: J. Med. Chem., 51, 7478 (2008); Jiang, W. et al.: Bioorg. Med. Med. Chem. Lett., 17, 5610 (2007);<br></p>

<p>Applications 4,4'-Bis(bromomethyl)-1,1'-biphenyl (cas# 20248-86-6) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications An unsaturated aldehyde used in the manufacture of polymers and synthetic resin. Cancer studies revealed consumption and release of this volatile organic compound in human small cell lung cancer line, a potential cancer biomarker.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponring, A. et al.: Cancer Biomarkers, 7, 153 (2010); Ligor, M. et al.; Clin. Chem. Lab. Med., 47, 550 92009);<br></p>

<p>Applications A synthetic, quaternary ammonium anticholinergic. Antispasmodic; preanesthetic medicant.<br>References Kaltiala, E., et al.: J. Pharm. Pharmacol., 26, 352 (1974), Kongsrud, F., et al.: Acta Anaesthesiol. Scand., 26, 620 (1982),<br></p>

<p>Applications Citraconic anhydride<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light Sensitive<br>Applications Stereomeric with Cinchonidine (C441925). Antimalarial.<br>References Litchfield, J., et al.: J. Pharm. Exp. Ther., 96, 99 (1949), Trager, W., et al.: Science, 193, 673 (1976), Panisko, D., et al.: Drugs, 39, 160 (1990), Karle, J., et al.: Antimicrob. Agents Chemother., 36, 1538 (1992),<br></p>

<p>Applications Icilin is a potent agonist of the TRPM8 and ENaCδ ion channels.<br>References Noncovich, A., et al.: Bioorganic Med. Chem. Lett., 27, 3931-38 (2017);<br></p>

<p>Applications WAY 127039-A-1 is a metabolite of Bromfenac sodium (B678550).<br>References Walsh, D.A., et al.: J. Med. Chem., 25, 446 (1982),<br></p>

<p>Applications Tandospirone is a 5HT1A receptor partial agonist. Studies indicate that tandospirone significantly reduces haloperidol-induced bradykinesia in a dose dependent manner. The potency of Tandospirone is equal to that of buspirone and approximate one-half that of diazepam. The potency of Tandospirone at dopamine antagonistic action is less than 1/4 that of buspirone.<br>References Seymour, P.A., et al.: Prog. Clin. Biol. Res., 361, 453 (1990), Evans, S.M., et al.: J. Pharmacol. Exp. Ther., 271, 683 (1994),<br></p>

<p>Applications A MEK inhibitor with antitumor activity.<br>References Lee, W., et al.: Bioorg. Med. Chem. Lett., 15, 3573 (2005), Normanno, N., et al.: J. Cell. Physiology, 207, 420 (2006), Narlawar, R., et al.: J. Med. Chem., 49, 7588 (2006),<br></p>

<p>Applications (R)-1-[(SP)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine is a Josiphos ligand.<br>References MacQueen, P., et al.: Chemistry - A European Journal, 21, 11006 (2015);<br></p>

<p>Applications 1-Hexyne is a reagent used in the preparation of triazole hydroxamic acid derivatives as selective MMP-2 inhibitors using click chemistry. 1-Hexyne is a potent inhibitor of nitrification in soil. A reagent for the preparation of functionalized isoindolinones via ring closing metathesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zapico, J., et al.: Anales de la Real Academia Nacional de Farmacia, 77, 99 (2011); El-Sayed, S., et al.: Alexandria Sci. Exchange, 24, 327 (2003); Pierce, J. G., et al.: J. Organomet. Chem., 692, 4618 (2007)<br></p>

<p>Applications β-Glycerol Phosphate was shown to have promoted mineralization in vitro by modulating bone cell metabolic activity and/or serving as a local source of inorganic phosphate ions.<br>References Chung, C.H., et al.: Calcif. Tissue. Int., 51, 305 (1992);<br></p>

<p>Applications An inhibitor of serotonin (5-HT) uptake. Antidepressant.<br>References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001),<br></p>

<p>Applications IHydroxylamine, is a useful reactant used that is mainly used as a reducing agent in organic reactions.<br></p>

<p>Applications Sulbactam Pivoxil is a prodrug of the semi-synthetic β-lactamase inhibitor Sulbactam (S699195).<br>References Foulds, G. et al.: Curr. Chemother. Infect. Dis., Proc. Int. Congr. Chemother., 11, 353 (1980); Pei, Q. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 879, 2000 (2011);<br></p>

<p>Applications Used in the synthesis of (4S,5S)-(-)-isocytoxazone.<br>References Kakeya, H., et al.: J. Antibiot., 51, 1126 (1998), Carter, P., et al.: Bioorg. Med. Chem. Lett., 13, 1237 (2003),<br></p>

<p>Applications Ipratropium Bromide is a nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.<br>References Groeben, H., et al.: Anesthesiology, 85, 867 (1996); Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999); Barnes, P. J., et al.: Chest, 117, 63S (2000)<br></p>