Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Found 79283 products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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Selexipag
CAS:Controlled Product<p>Applications Selexipag is an orally available, highly selective, long-acting prostacyclin (IP) receptor agonist prodrug. It is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Formula:C26H32N4O4SColor and Shape:Light YellowMolecular weight:496.62Pramipexole Dihydrochloride Monohydrate
CAS:Formula:C10H17N3S(HCl)H2OMolecular weight:211.3 : 2(36.5) : 18.0Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
CAS:Formula:C14H13NO4SMolecular weight:291.32Amlodipine EP Impurity D (Oxalate salt)
CAS:Formula:C20H23ClN2O5C2H2O4Molecular weight:406.86 : 90.031-Chloroethyl Cyclohexyl Carbonate
CAS:<p>Applications 1-Chloroethyl Cyclohexyl Carbonate is a genotoxic impurity used in the synthesis of Candesartan Cilexetil. an angiotensin II receptor antagonist.<br>References Kakasaheb, N. et al.: Int. J. Pharm. Sci., 6, 370 (2014); Mao, Y. et al.: Heterocycles, 81, 1503 (2010);<br></p>Formula:C9H15ClO3Color and Shape:NeatMolecular weight:206.67Octenidine Dihydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Octenidine is an antiseptic (topical). Octenidine is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative.<br>References Slee, A.M., et al.: Antimicrob. Agents Chemother., 23, 531 (1983), Ghannoum, M.A., et al.: J. Antimicrob. Chemother., 25, 237 (1990), Allen, M., et al.: Microbiology, 152, 989 (2006), Ojha, A., et al.: Mol. Microbiol., 66, 468 (2007),<br></p>Formula:C36H62N4·2HClColor and Shape:White To Off-WhiteMolecular weight:623.83Probenecid
CAS:Controlled Product<p>Applications Uricosuric.<br>References McKinney, S.E., et al.: J. Pharmacol. Exp. Ther., 102, 208 (1951), Israili, Z.H., et al.: J. Med. Chem., 15, 709 (1972), Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 10, 639 (1981), Cunningham, R.F., et al.: Clin. Pharmacokinet., 6, 135 (1981),<br></p>Formula:C13H19NO4SColor and Shape:WhiteMolecular weight:285.36Febuxostat
CAS:<p>Applications Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Formula:C16H16N2O3SColor and Shape:White To Off-WhiteMolecular weight:316.37(2R,3aR,6aR)-Ramipril
CAS:Controlled Product<p>Impurity Ramipril EP Impurity N<br>Applications (2R,3aR,6aR)-Ramipril (Ramipril EP Impurity N) is an isomer of the angiotensin-converting enzyme (ACE) inhibitor Ramipril (R111000). Ramipril impurity N.<br>References Hogan, B.L. et al.: J. Pharmac. Biomed. Anal., 23, 637 (2000); Ito, M. et al.: J. Liq. Chrom., 13, 991 (1990);<br></p>Formula:C23H32N2O5Color and Shape:White To Off-WhiteMolecular weight:416.51Travoprost
CAS:<p>Stability Light Sensitive<br>Applications Travoprost is a selective FP prostaglandin receptor agonist used to treat glaucoma (1,2).<br>References (1) Hellberg, M.R., et al.: J. Ocul. Pharmacol. Ther., 17, 421 (2001) (2) Schuman, J.S., et al.: Am. J. Ophthalmol., 140, 242 (2005)<br></p>Formula:C26H35F3O6Color and Shape:Colourless To BeigeMolecular weight:500.554-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone
CAS:Controlled Product<p>Impurity Rivaroxaban Impurity E<br>Applications 4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone (Rivaroxaban Impurity E) is an impurity of Rivaroxaban (R538000), which is a antithrombotic agent and a FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C13H17ClN2O3Color and Shape:NeatMolecular weight:284.741,2,3,4-Tetradehydro Argatroban
CAS:Controlled Product<p>Applications 1,2,3,4-Tetrahydro Argatroban is a metabolite of Argatroban (A769000); a synthetic thrombin inhibitor and antithrombotic.<br>References Abiko, Y., et al.: Thromb. Res., 24, 285 (1981); Kikumoto, R., et al.: Biochemistry, 23, 85 (1984)<br></p>Formula:C23H32N6O5SColor and Shape:NeatMolecular weight:504.60(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
CAS:Controlled Product<p>Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate used to prepare trans-2-arylcyclopropylamines as potent and selective dipeptidyl peptidase IV inhibitors.<br>References Tsai, T., et al.: Bioorg. Med. Chem., 17, 2388 (2009)<br></p>Formula:C9H9F2N·HClColor and Shape:Off White SolidMolecular weight:205.632Riluzole-13C,15N2
CAS:Controlled ProductFormula:C713CH5F315N2OSColor and Shape:Light Beige To Light YellowMolecular weight:237.18Perindoprilat Lactam A
CAS:<p>Impurity Perindopril EP Impurity C<br>Applications Perindoprilat Lactam A (Perindopril EP Impurity C) is the active metabolite of Perindopril (P287500) in plasma and urine.<br>References Hillaert, S., et al.: J. Pharm. Biomed. Anal., 25, 775 (2001), Ozoemena, K., et al.: Talanta, 62, 681 (2004),<br></p>Formula:C17H26N2O4Color and Shape:White To BeigeMolecular weight:322.40trans-Latanoprost
CAS:<p>Impurity Latanoprost USP Related Compound A<br>Stability Temperature Sensitive<br>Applications Prostaglandin analog; prodrug of active acid metabolite. It is a synthetic derivative of the natural prostaglandin PGF2α, used as an anti-glaucoma agent that is effective in various types of glaucoma and ocular hypertension. Latanoprost USP Related Compound A.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993), Toris, C., et al.: Ophthalmology, 100, 1297 (1993), Holmstrom, S., et al.: Curr. Med. Res. Op., 21, 1875 (2005),<br></p>Formula:C26H40O5Color and Shape:ColourlessMolecular weight:432.59Tolvaptan
CAS:Controlled Product<p>Applications Tolvaptan is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).<br>References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006);<br></p>Formula:C26H25ClN2O3Color and Shape:White To Off-WhiteMolecular weight:448.94
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