Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Anisomycin
CAS:<p>Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.</p>Fórmula:C14H19NO4Pureza:98.33% - 99.81%Cor e Forma:White Crystalline SolidPeso molecular:265.3ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Fórmula:C22H29ClN4O3Pureza:97.43% - 98.4%Cor e Forma:SolidPeso molecular:432.94Lorlatinib
CAS:<p>Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene</p>Fórmula:C21H19FN6O2Pureza:99.77% - 99.95%Cor e Forma:SolidPeso molecular:406.41MFCD01917484
CAS:<p>MFCD01917484: A thiophene derivative with ligand, catalyst, and photosensitizer roles, used in biochemical research and drug development.</p>Fórmula:C14H15NO3SPureza:98.09%Cor e Forma:SolidPeso molecular:277.34Taccalonolide A
CAS:<p>Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is</p>Fórmula:C36H46O14Pureza:98.16% - 99.4%Cor e Forma:SolidPeso molecular:702.74Onatasertib
CAS:<p>Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.</p>Fórmula:C21H27N5O3Pureza:99.14% - 99.97%Cor e Forma:SolidPeso molecular:397.47β-Elemonic Acid
CAS:<p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>Fórmula:C30H46O3Pureza:99.61% - 99.8%Cor e Forma:SolidPeso molecular:454.68BAY 11-7082
CAS:<p>BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).</p>Fórmula:C10H9NO2SPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:207.25(6R)-FR054
CAS:<p>(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.</p>Fórmula:C14H19NO8Pureza:99.61%Cor e Forma:SolidPeso molecular:329.3(-)-Epipodophyllotoxin
CAS:<p>(-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.</p>Fórmula:C22H22O8Pureza:99.97%Cor e Forma:SolidPeso molecular:414.41PD173074
CAS:<p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>Fórmula:C28H41N7O3Pureza:98.15% - 98.21%Cor e Forma:Yellow SolidPeso molecular:523.67JNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Fórmula:C15H12F2N6O3SPureza:99.1% - 99.85%Cor e Forma:SolidPeso molecular:394.36WP1066
CAS:<p>WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.</p>Fórmula:C17H14BrN3OPureza:98.92% - 99.73%Cor e Forma:SolidPeso molecular:356.22Gemcitabine hydrochloride
CAS:<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Cor e Forma:White Crystalline Granular OdorlessPeso molecular:299.66AZ960
CAS:<p>AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).</p>Fórmula:C18H16F2N6Pureza:96.02% - 98.51%Cor e Forma:SolidPeso molecular:354.36AEE788
CAS:<p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>Fórmula:C27H32N6Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:440.5818α-Glycyrrhetinic acid
CAS:<p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>Fórmula:C30H46O4Pureza:98.54% - 99.68%Cor e Forma:SolidPeso molecular:470.68Antineoplaston A10
CAS:<p>Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.</p>Fórmula:C13H14N2O3Pureza:99.42%Cor e Forma:SolidPeso molecular:246.26Valepotriate
CAS:<p>Valepotriates are sedative, enhance memory, have anti-cancer properties, and may reduce anxiety.</p>Fórmula:C22H30O8Pureza:97.29% - 99.90%Cor e Forma:SolidPeso molecular:422.47(E)-Flavokawain A
CAS:<p>(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway.</p>Fórmula:C18H18O5Pureza:98% - 99.75%Cor e Forma:SolidPeso molecular:314.332Atractylenolide III
CAS:<p>Atractylenolide III could treat cognitive issues and lung cancer by modulating apoptosis factors.</p>Fórmula:C15H20O3Pureza:99.53% - 99.82%Cor e Forma:SolidPeso molecular:248.32Oleuropein
CAS:<p>Oleuropein is an antioxidant polyphenol isolated from olive leaf.</p>Fórmula:C25H32O13Pureza:98% - 99.95%Cor e Forma:Brown PowderPeso molecular:540.51Columbianadin
CAS:Columbianadin (Zosimin), one of the main bioactive constituents of the roots of Angelica pubescens Maxim.Fórmula:C19H20O5Pureza:98.44% - 99.48%Cor e Forma:SolidPeso molecular:328.36Flavokawain C
CAS:<p>Flavokawain C: natural chalcone from Kava with potential as a colon cancer drug.</p>Fórmula:C17H16O5Pureza:99.94% - ≥95%Cor e Forma:SolidPeso molecular:300.31GSK2606414
CAS:<p>GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase（PERK）inhibitor.Cost-effective and quality-assured.</p>Fórmula:C24H20F3N5OPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:451.44PK11007
CAS:<p>PK11007 is an anti-p53 drug.</p>Fórmula:C15H11ClFN5O3S2Pureza:97.55%Cor e Forma:SolidPeso molecular:427.86Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Fórmula:C29H34N6O4S2Pureza:97.67% - 98.44%Cor e Forma:SolidPeso molecular:594.75Sulforaphene
CAS:<p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>Fórmula:C6H9NOS2Pureza:97.55% - 99.19%Cor e Forma:Slightly Yellowish LiquidPeso molecular:175.27Didanosine
CAS:<p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>Fórmula:C10H12N4O3Pureza:99.64%Cor e Forma:White Crystalline PowderPeso molecular:236.23Neogambogic acid
CAS:<p>Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect.</p>Fórmula:C38H46O9Pureza:97.74% - 99.38%Cor e Forma:SolidPeso molecular:646.77SB 415286
CAS:<p>SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.</p>Fórmula:C16H10ClN3O5Pureza:99.55%Cor e Forma:SolidPeso molecular:359.72SR-4835
CAS:<p>SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (</p>Fórmula:C21H20Cl2N10OPureza:98.09% - >99.99%Cor e Forma:SolidPeso molecular:499.36Indirubin
CAS:<p>Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.</p>Fórmula:C16H10N2O2Pureza:97.21% - 99.74%Cor e Forma:Reddish-Violet PowderPeso molecular:262.26UC2288
CAS:<p>UC2288, a Sorafenib-based p21 attenuator, reduces p21 levels without affecting its stability.</p>Fórmula:C20H18ClF6N3O2Pureza:99.75%Cor e Forma:SolidPeso molecular:481.82dBET6
CAS:<p>dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.</p>Fórmula:C42H45ClN8O7SPureza:97.57% - 99.12%Cor e Forma:SolidPeso molecular:841.37Carnosic acid
CAS:<p>Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.</p>Fórmula:C20H28O4Pureza:98.31% - 99.5%Cor e Forma:Yellow PowderPeso molecular:332.43MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Fórmula:C26H41N3O5Pureza:95% - 99.99%Cor e Forma:White To Off-White PowderPeso molecular:475.62Taurodeoxycholic acid sodium hydrate
CAS:<p>Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.</p>Fórmula:C26H46NNaO7SPureza:99.95%Cor e Forma:SolidPeso molecular:539.70Triglycidyl isocyanurate
CAS:<p>Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.</p>Fórmula:C12H15N3O6Pureza:99.01%Cor e Forma:White Solid ParticulatesPeso molecular:297.26GSK4112
CAS:<p>GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.</p>Fórmula:C18H21ClN2O4SPureza:99.69%Cor e Forma:SolidPeso molecular:396.89CCF642
CAS:<p>CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.</p>Fórmula:C15H10N2O4S3Pureza:97.12% - 98.82%Cor e Forma:SolidPeso molecular:378.45PFI-90
CAS:<p>PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity.</p>Fórmula:C11H10N4OPureza:99.46%Cor e Forma:SolidPeso molecular:214.22Triptonide
CAS:<p>Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.</p>Fórmula:C20H22O6Pureza:99.11% - 99.64%Cor e Forma:White Crystalline PowderPeso molecular:358.39Nelarabine
CAS:<p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>Fórmula:C11H15N5O5Pureza:98.10% - 99.6%Cor e Forma:White SolidPeso molecular:297.27Abacavir sulfate
CAS:<p>Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity</p>Fórmula:C14H18N6OH2O4SPureza:99.79% - 99.85%Cor e Forma:White To Off-White SolidPeso molecular:335.38Prucalopride Succinate
CAS:<p>Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).</p>Fórmula:C18H26ClN3O3·C4H6O4Pureza:99.24%Cor e Forma:SolidPeso molecular:485.96Bromosporine
CAS:<p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>Fórmula:C17H20N6O4SPureza:99.65% - 99.79%Cor e Forma:SolidPeso molecular:404.44Hispidol
CAS:<p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>Fórmula:C15H10O4Pureza:97.86% - 98.45%Cor e Forma:SolidPeso molecular:254.244-Methyldaphnetin
CAS:<p>4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.</p>Fórmula:C10H8O4Pureza:99.73%Cor e Forma:SolidPeso molecular:192.17Brevilin A
CAS:<p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>Fórmula:C20H26O5Pureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:346.42Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Fórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:498.4Actein
CAS:<p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>Fórmula:C37H56O11Pureza:≥98%Cor e Forma:Brown PowderPeso molecular:676.83UCF 101
CAS:<p>UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.</p>Fórmula:C27H17N3O5SPureza:99.64%Cor e Forma:SolidPeso molecular:495.51Gomisin N
CAS:<p>Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.</p>Fórmula:C23H28O6Pureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:400.46PHYTOSPHINGOSINE
CAS:<p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>Fórmula:C18H39NO3Pureza:99.81%Cor e Forma:SolidPeso molecular:317.51AZD-7648
CAS:<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Fórmula:C18H20N8O2Pureza:99.03% - 99.85%Cor e Forma:SolidPeso molecular:380.4Verbascoside
CAS:<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Fórmula:C29H36O15Pureza:97.46% - 99.55%Cor e Forma:SolidPeso molecular:624.59CAY10404
CAS:<p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>Fórmula:C17H12F3NO3SPureza:99.02%Cor e Forma:SolidPeso molecular:367.34Picroside II
CAS:<p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>Fórmula:C23H28O13Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:512.46Desmethylanethol trithione
CAS:<p>Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.</p>Fórmula:C9H6OS3Pureza:98.05% - 98.41%Cor e Forma:SolidPeso molecular:226.34ONC212
CAS:<p>ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.</p>Fórmula:C24H23F3N4OPureza:99.79%Cor e Forma:SolidPeso molecular:440.46β-Ionone
CAS:<p>β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastatic</p>Fórmula:C13H20OPureza:98.52%Cor e Forma:Colourless Liquid OilyPeso molecular:192.3GS-444217
CAS:<p>GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).</p>Fórmula:C23H21N7OPureza:99.08%Cor e Forma:SolidPeso molecular:411.46OUL35
CAS:<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Fórmula:C14H12N2O3Pureza:99.2%Cor e Forma:SolidPeso molecular:256.26TCPOBOP
CAS:<p>TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.</p>Fórmula:C16H8Cl4N2O2Pureza:99.7%Cor e Forma:SolidPeso molecular:402.06B355252
CAS:<p>B355252 prevents glutamate-induced cell death and boosts NGF's nerve growth effects.</p>Fórmula:C25H24ClN3O3S2Pureza:98.73% - 99.92%Cor e Forma:SolidPeso molecular:514.06PD0166285
CAS:<p>PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.</p>Fórmula:C26H27Cl2N5O2Pureza:99.23%Cor e Forma:SolidPeso molecular:512.43AC1NS4RE
CAS:<p>It is a tyrosine kinase inhibitor.</p>Fórmula:C15H13ClN2OPureza:99.53%Cor e Forma:SolidPeso molecular:272.73Acacetin
CAS:<p>Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant</p>Fórmula:C16H12O5Pureza:96.26% - ≥95%Cor e Forma:Pale-Yellow NeedlesPeso molecular:284.26VK3-OCH3
CAS:<p>VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.</p>Fórmula:C14H14O3SPureza:99.71%Cor e Forma:SolidPeso molecular:262.32CAY10505
CAS:<p>CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).</p>Fórmula:C14H8FNO3SPureza:99.69% - 99.74%Cor e Forma:SolidPeso molecular:289.28MRS 2578
CAS:MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.Fórmula:C20H20N6S4Pureza:97.58% - 99.73%Cor e Forma:White SolidPeso molecular:472.67Polyphyllin I
CAS:<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Fórmula:C44H70O16Pureza:98% - 99.5%Cor e Forma:SolidPeso molecular:855.02Epothilone A
CAS:<p>Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.</p>Fórmula:C26H39NO6SPureza:99.89% - 99.92%Cor e Forma:SolidPeso molecular:493.66Fedratinib hydrochloride hydrate
CAS:<p>Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.</p>Fórmula:C27H40Cl2N6O4SPureza:98.96% - 99.87%Cor e Forma:SolidPeso molecular:615.61G5-7
CAS:<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Fórmula:C22H19F2NO3Pureza:97.3%Cor e Forma:SolidPeso molecular:383.39Alginic acid
CAS:<p>Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.</p>Fórmula:C14H22O13Pureza:≥98%Cor e Forma:SolidPeso molecular:398.317OTS514 hydrochloride
CAS:<p>OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).</p>Fórmula:C21H20N2O2S·HClPureza:99.67% - 99.84%Cor e Forma:SolidPeso molecular:400.92Kynurenic acid sodium
CAS:<p>Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.</p>Fórmula:C10H6NNaO3Pureza:99.47%Cor e Forma:SolidPeso molecular:211.15MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Fórmula:C27H34ClNO2SPureza:99.23% - 99.84%Cor e Forma:SolidPeso molecular:472.08Xanthatin
CAS:<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>Fórmula:C15H18O3Pureza:98.48% - 99.96%Cor e Forma:SolidPeso molecular:246.3CASIN
CAS:<p>CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).</p>Fórmula:C20H22N2OPureza:98.18% - >99.99%Cor e Forma:SolidPeso molecular:306.4NU 7026
CAS:<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Fórmula:C17H15NO3Pureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:281.314EGI-1
CAS:<p>4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).</p>Fórmula:C18H12Cl2N4O4SPureza:96.8% - 99.12%Cor e Forma:SolidPeso molecular:451.28Lithocholic acid
CAS:<p>Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!</p>Fórmula:C24H40O3Pureza:99.69% - 99.93%Cor e Forma:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecular:376.57SKF-96365 hydrochloride
CAS:<p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>Fórmula:C22H27ClN2O3Pureza:99.47% - 99.92%Cor e Forma:SolidPeso molecular:402.91Xanthohumol
CAS:<p>Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-</p>Fórmula:C21H22O5Pureza:98.19% - 99.67%Cor e Forma:Orange PowderPeso molecular:354.4NSC 66811
CAS:<p>NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.</p>Fórmula:C23H20N2OPureza:96.94%Cor e Forma:SolidPeso molecular:340.42Palmatine
CAS:<p>Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.</p>Fórmula:C21H22NO4Pureza:96.28% - 99.49%Cor e Forma:SolidPeso molecular:352.4Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Cor e Forma:SolidPeso molecular:570.64Suramin Sodium Salt
CAS:<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Fórmula:C51H34N6Na6O23S6Pureza:97.47% - 99.97%Cor e Forma:WhitePeso molecular:1429.15(S)-10-Hydroxycamptothecin
CAS:<p>(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.</p>Fórmula:C20H16N2O5Pureza:99.09% - 99.81%Cor e Forma:SolidPeso molecular:364.35AZD0156
CAS:<p>AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.</p>Fórmula:C26H31N5O3Pureza:99.13% - 99.87%Cor e Forma:SolidPeso molecular:461.56TG101209
CAS:<p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>Fórmula:C26H35N7O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:509.67MGCD-265 analog
CAS:<p>Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.</p>Fórmula:C26H20FN5O2S2Pureza:98.06% - 98.68%Cor e Forma:SolidPeso molecular:517.6Ginsenoside Rg1
CAS:<p>Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).</p>Fórmula:C42H72O14Pureza:99% - 99.74%Cor e Forma:White Crystalline PowderPeso molecular:801.01Valinomycin
CAS:<p>Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin</p>Fórmula:C54H90N6O18Pureza:95.37% - 97.16%Cor e Forma:White SolidPeso molecular:1111.32Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Fórmula:C11H18FNO5Pureza:≥98%Cor e Forma:SolidPeso molecular:263.26LYN-1604
CAS:<p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>Fórmula:C33H43Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:584.62BMS-202
CAS:<p>BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.</p>Fórmula:C25H29N3O3Pureza:97.92% - 99.66%Cor e Forma:SolidPeso molecular:419.52SP2509
CAS:<p>SP2509 is a specific histone demethylase LSD1 inhibitor(IC50 =13 nM).</p>Fórmula:C19H20ClN3O5SPureza:98.82% - 99.53%Cor e Forma:SolidPeso molecular:437.9PU02
CAS:<p>PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.</p>Fórmula:C16H12N4SPureza:99.35%Cor e Forma:SolidPeso molecular:292.36Kaempferol
CAS:<p>Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.</p>Fórmula:C15H10O6Pureza:98% - 99.41%Cor e Forma:Yellow Needles From Alcohol And Water SolidPeso molecular:286.24physalin F
CAS:<p>Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.Cost-effective and quality-assured.</p>Fórmula:C28H30O10Pureza:99.5% - 99.61%Cor e Forma:SolidPeso molecular:526.53Apitolisib
CAS:<p>Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).</p>Fórmula:C23H30N8O3SPureza:98.28% - 99.64%Cor e Forma:SolidPeso molecular:498.6Kobe0065
CAS:<p>Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.</p>Fórmula:C15H11ClF3N5O4SPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:449.79α-Mangostin
CAS:<p>alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.</p>Fórmula:C24H26O6Pureza:98.22% - 99.49%Cor e Forma:Yellow PowderPeso molecular:410.46DPN
CAS:<p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>Fórmula:C15H13NO2Pureza:99.01%Cor e Forma:Off-White SolidPeso molecular:239.27Selumetinib
CAS:<p>Selumetinib (AZD6244) is a selectivity and non-ATP-competitive MEK1/2 inhibitor. Selumetinib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C17H15BrClFN4O3Pureza:98.1% - 99.90%Cor e Forma:White Or Pale White SolidPeso molecular:457.68SM-164
CAS:<p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>Fórmula:C62H84N14O6Pureza:98.53% - 99.92%Cor e Forma:SolidPeso molecular:1121.42FTI-277 hydrochloride
CAS:<p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>Fórmula:C22H30ClN3O3S2Pureza:97.57% - 97.61%Cor e Forma:SolidPeso molecular:484.07CID5721353
CAS:<p>CID5721353 disrupts BCL6/corepressor complexes, binds critical BTB groove site in vitro/vivo.</p>Fórmula:C15H9BrN2O6S2Pureza:98.90%Cor e Forma:SolidPeso molecular:457.28Nutlin-3a
CAS:<p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C30H30Cl2N4O4Pureza:95.62% - 99.71%Cor e Forma:SolidPeso molecular:581.49Apoptozole
CAS:<p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>Fórmula:C33H25F6N3O3Pureza:99.75%Cor e Forma:SolidPeso molecular:625.56Quisinostat dihydrochloride
CAS:<p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>Fórmula:C21H28Cl2N6O2Pureza:97.13%Cor e Forma:SolidPeso molecular:467.39Atopaxar hydrochloride
CAS:<p>Atopaxar hydrochloride is used in the Treatment of Cardiovascular Disorders.</p>Fórmula:C29H39ClFN3O5Cor e Forma:SolidPeso molecular:564.1R1530
CAS:<p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>Fórmula:C18H14ClFN4OPureza:98.422%Cor e Forma:SolidPeso molecular:356.78Y-27632
CAS:<p>Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.</p>Fórmula:C14H21N3OPureza:99.53% - 99.87%Cor e Forma:SolidPeso molecular:247.34Calpeptin
CAS:<p>Calpeptin is a potent, cell-permeable calpain inhibitor.</p>Fórmula:C20H30N2O4Pureza:97.06% - 98.33%Cor e Forma:White To Off-White PowderPeso molecular:362.463-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Fórmula:C3H3BrO3Pureza:95% - 99.644%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:166.96Fangchinoline
CAS:<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Fórmula:C37H40N2O6Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:608.72Lexibulin
CAS:<p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>Fórmula:C24H30N6O2Pureza:98.87%Cor e Forma:SolidPeso molecular:434.53Cucurbitacin IIb
CAS:<p>Cucurbitacin IIb is an active ingredient in Hemsleyadine, used to treat dysentery and other infections; it has anti-inflammatory effects.</p>Fórmula:C30H48O7Pureza:98.66% - >99.99%Cor e Forma:SolidPeso molecular:520.7Poncirin
CAS:<p>Poncirin inhibits human gastric cancer cell growth and prevents fat formation while boosting bone density and improving structure in osteoporosis mice.</p>Fórmula:C28H34O14Pureza:99.89% - 99.92%Cor e Forma:SolidPeso molecular:594.56Entinostat
CAS:<p>Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H20N4O3Pureza:98% - 99.74%Cor e Forma:SolidPeso molecular:376.41Ligustilide
CAS:<p>3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.</p>Fórmula:C12H14O2Pureza:96.03% - 98.14%Cor e Forma:Yellow Brown PowderPeso molecular:190.24Dioscin
CAS:<p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>Fórmula:C45H72O16Pureza:99.85% - 99.87%Cor e Forma:SolidPeso molecular:869.04JIB-04
CAS:<p>JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor.</p>Fórmula:C17H13ClN4Pureza:98.02% - 98.87%Cor e Forma:SolidPeso molecular:308.76Tebufenozide
CAS:<p>Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests.</p>Fórmula:C22H28N2O2Pureza:98%Cor e Forma:SolidPeso molecular:352.47Y-320
CAS:<p>Y-320 is a new phenylpyrazoleanilide immunomodulator.</p>Fórmula:C27H29ClN6O2Pureza:98% - 99.64%Cor e Forma:SolidPeso molecular:505.01PIK-75 hydrochloride
CAS:<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Fórmula:C16H14BrN5O4S·HClPureza:97.82%Cor e Forma:SolidPeso molecular:488.745-Aminolevulinic acid hydrochloride
CAS:<p>5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.</p>Fórmula:C5H10ClNO3Pureza:98% - 99.97%Cor e Forma:White To Pale Yellow Crystals OrPeso molecular:167.59Pulsatilla saponin D
CAS:<p>Pulsatilla saponin D (Hederacolchiside A) may prevent cancer, hindering cancer cell growth through cell cycle arrest and apoptosis.</p>Fórmula:C47H76O17Pureza:99.55%Cor e Forma:SolidPeso molecular:913.1Fludarabine Phosphate
CAS:<p>Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.</p>Fórmula:C10H13FN5O7PPureza:99.25% - 99.78%Cor e Forma:SolidPeso molecular:365.21L-Theanine
CAS:<p>L-Theanine, a unique amino acid from Camellia sinensis tea, induces relaxation without drowsiness.</p>Fórmula:C7H14N2O3Pureza:99.31% - 99.38%Cor e Forma:White Crystals From Ethanol + Water White Crystalline SolidPeso molecular:174.2Glaucocalyxin A
CAS:<p>Glaucocalyxin A improves drug delivery, activates apoptosis, inhibits cell growth, with potential as an antiplatelet agent.</p>Fórmula:C20H28O4Pureza:99.55% - 99.80%Cor e Forma:SolidPeso molecular:332.43Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Fórmula:C18H15N5OPureza:97.03%Cor e Forma:SolidPeso molecular:317.34Pyroxamide
CAS:<p>Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).</p>Fórmula:C13H19N3O3Pureza:98.46%Cor e Forma:SolidPeso molecular:265.31Pinoresinol
CAS:<p>Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury</p>Fórmula:C20H22O6Pureza:98.67%Cor e Forma:SolidPeso molecular:358.391-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:<p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>Fórmula:C21H13ClF3N3O2Pureza:99.41%Cor e Forma:SolidPeso molecular:431.82-Deoxy-D-glucose
CAS:<p>2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis.</p>Fórmula:C6H12O5Pureza:99.31% - ≥98%Cor e Forma:White PowderPeso molecular:164.16BX-912
CAS:<p>BX-912 inhibits PDK1 with IC50 of 12 nM; over 10x more selective versus C-Kit, EGFR, PKA, PKC.</p>Fórmula:C20H23BrN8OPureza:98.29% - 99.34%Cor e Forma:SolidPeso molecular:471.35Supinoxin
CAS:<p>Supinoxin (RX-5902) is an oral anti-cancer drug targeting p68 RNA helicase, inducing apoptosis in TNBC cells (IC50: 10-20nM).</p>Fórmula:C22H24FN5O4Pureza:99.83% - 99.95%Cor e Forma:SolidPeso molecular:441.46GDC-0152
CAS:<p>GDC-0152 is a potent inhibitor of IAPs.</p>Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Cor e Forma:SolidPeso molecular:498.64CCT128930 hydrochloride
CAS:<p>CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.</p>Fórmula:C18H21Cl2N5Pureza:98.55%Cor e Forma:SolidPeso molecular:378.3Lobaplatin
CAS:<p>Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.</p>Fórmula:C9H18N2O3PtPureza:98.00%Cor e Forma:SolidPeso molecular:397.33L-Asparaginase
CAS:<p>L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.</p>Fórmula:NAPureza:97%Cor e Forma:SolidPeso molecular:N/ASGI-1776
CAS:<p>SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.</p>Fórmula:C20H22F3N5OPureza:99.3% - >99.99%Cor e Forma:SolidPeso molecular:405.42Elesclomol
CAS:<p>Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier.</p>Fórmula:C19H20N4O2S2Pureza:97.17% - 99.51%Cor e Forma:SolidPeso molecular:400.52Rilmenidine Phosphate
CAS:<p>Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.</p>Fórmula:C10H19N2O5PPureza:99.87% - ≥95%Cor e Forma:SolidPeso molecular:278.24HO-3867
CAS:<p>HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.</p>Fórmula:C28H30F2N2O2Pureza:91.18% - 99.21%Cor e Forma:SolidPeso molecular:464.55LRRK2-IN-1
CAS:<p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>Fórmula:C31H38N8O3Pureza:98% - 98.82%Cor e Forma:SolidPeso molecular:570.69kauran-16,17-diol
CAS:<p>Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7</p>Fórmula:C20H34O2Pureza:99.93%Cor e Forma:SolidPeso molecular:306.48Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Fórmula:C9H6O4Pureza:97.47% - 99.8%Cor e Forma:SolidPeso molecular:178.14S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Fórmula:C22H21NO2SPureza:97.02%Cor e Forma:Almost White To Light Yellow Granular PowderPeso molecular:363.47NSC 95397
CAS:<p>NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).</p>Fórmula:C14H14O4S2Pureza:98.66%Cor e Forma:SolidPeso molecular:310.39Diffractaic Acid
CAS:<p>Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.</p>Fórmula:C20H22O7Pureza:99.81% - 99.87%Cor e Forma:SolidPeso molecular:374.38SKI II
CAS:<p>SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.</p>Fórmula:C15H11ClN2OSPureza:99.34% - 99.93%Cor e Forma:SolidPeso molecular:302.78[6]-Gingerol
CAS:<p>[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.</p>Fórmula:C17H26O4Pureza:98% - 99.66%Cor e Forma:Light Yellow OilinessPeso molecular:294.39STF-118804
CAS:<p>STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.</p>Fórmula:C25H23N3O4SPureza:98.66%Cor e Forma:SolidPeso molecular:461.53GSK1059615
CAS:<p>GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.</p>Fórmula:C18H11N3O2SPureza:99.3% - ≥95%Cor e Forma:SolidPeso molecular:333.36GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Fórmula:C43H46F3N7O7SPureza:98.78% - >99.99%Cor e Forma:SolidPeso molecular:861.932-Hydroxychalcone
CAS:<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Fórmula:C15H12O2Pureza:99.6%Cor e Forma:SolidPeso molecular:224.25Pracinostat
CAS:<p>Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oral</p>Fórmula:C20H30N4O2Pureza:99.15% - 99.67%Cor e Forma:SolidPeso molecular:358.48Phellamurin
CAS:<p>Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.</p>Fórmula:C26H30O11Pureza:97.91%Cor e Forma:SolidPeso molecular:518.51Astragalin
CAS:<p>Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid.</p>Fórmula:C21H20O11Pureza:98.8% - ≥95%Cor e Forma:SolidPeso molecular:448.38Dinaciclib
CAS:<p>Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).</p>Fórmula:C21H28N6O2Pureza:98.21% - 99.75%Cor e Forma:SolidPeso molecular:396.49Etidronic acid
CAS:<p>Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.</p>Fórmula:C2H8O7P2Pureza:99.93% - ≥95%Cor e Forma:Liquid SyrupPeso molecular:206.03Nafamostat mesylate
CAS:<p>Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis</p>Fórmula:C19H17N5O2·2CH4O3SPureza:97.36% - 99.76%Cor e Forma:Tan To Pale Orange SolidPeso molecular:539.58KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Fórmula:C20H20N4OPureza:98.43% - 99.69%Cor e Forma:SolidPeso molecular:332.4WYC-209
CAS:<p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>Fórmula:C20H20N2O3SPureza:99.77%Cor e Forma:SolidPeso molecular:368.45Amentoflavone
CAS:<p>Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.</p>Fórmula:C30H18O10Pureza:98.21% - 99.22%Cor e Forma:Odourless Whitish SolidPeso molecular:538.46BAY 61-3606
CAS:<p>BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting</p>Fórmula:C20H18N6O3Pureza:98.72%Cor e Forma:SolidPeso molecular:390.4BAY 87-2243
CAS:<p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>Fórmula:C26H26F3N7O2Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:525.53Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Fórmula:C26H30N4O5SPureza:97.7% - 98.41%Cor e Forma:SolidPeso molecular:510.61Sacubitril/Valsartan
CAS:<p>Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for treatment of hypertension and heart failure.</p>Fórmula:C48H55N6O8Na3·5H2OPureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:957.99SKI-178
CAS:<p>SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM.</p>Fórmula:C21H22N4O4Pureza:97.09%Cor e Forma:SolidPeso molecular:394.42Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Cor e Forma:SolidPeso molecular:718.08Etretinate
CAS:<p>Etretinate (Ro 10-9359), an oral retinoid, treats psoriasis by promoting cell differentiation and reducing cell growth and inflammation.</p>Fórmula:C23H30O3Pureza:97.89%Cor e Forma:Crystals Crystalline SolidPeso molecular:354.48Sepantronium bromide
CAS:<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Fórmula:C20H19BrN4O3Pureza:99.68% - 99.85%Cor e Forma:SolidPeso molecular:443.26Psoralen
CAS:<p>Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.</p>Fórmula:C11H6O3Pureza:99.3% - 99.87%Cor e Forma:Crystals From Ether Crystalline SolidPeso molecular:186.16Clodronate disodium tetrahydrate
CAS:<p>Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.</p>Fórmula:CH10Cl2Na2O10P2Pureza:98%Cor e Forma:SolidPeso molecular:360.92CM-272
CAS:<p>CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.</p>Fórmula:C28H38N4O3Pureza:97.83%Cor e Forma:SolidPeso molecular:478.63Isolongifolene
CAS:<p>Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and</p>Fórmula:C15H24Pureza:90.13% - 99.46%Cor e Forma:Colorless Or Light Yellow LiquidPeso molecular:204.35ERK1/2 inhibitor 2
CAS:<p>ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.</p>Fórmula:C29H31ClFN5O5Pureza:98.99%Cor e Forma:SolidPeso molecular:584.04Trifloxystrobin
CAS:<p>Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.</p>Fórmula:C20H19F3N2O4Pureza:99.49%Cor e Forma:SolidPeso molecular:408.37LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Fórmula:C19H17NO3Pureza:98% - 99.96%Cor e Forma:Pale Yellow SolidPeso molecular:307.34JKE-1674
CAS:<p>JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.</p>Fórmula:C20H20Cl2N4O4Pureza:98.02% - 98.4%Cor e Forma:SolidPeso molecular:451.3QNZ
CAS:<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Fórmula:C22H20N4OPureza:99.17% - 99.18%Cor e Forma:White SolidPeso molecular:356.42Bardoxolone
CAS:<p>Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.</p>Fórmula:C31H41NO4Pureza:97.9% - 98.97%Cor e Forma:SolidPeso molecular:491.66Thalidomide-O-C4-NH2 hydrochloride
CAS:<p>Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.</p>Fórmula:C17H20ClN3O5Pureza:98.33%Cor e Forma:SolidPeso molecular:381.81Dihydrocapsaicin
CAS:<p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>Fórmula:C18H29NO3Pureza:99.61% - ≥95%Cor e Forma:White CrystalPeso molecular:307.43Laquinimod sodium
CAS:<p>Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.</p>Fórmula:C19H16ClN2NaO3Cor e Forma:SolidPeso molecular:378.79Thalidomide-PEG4-Propargyl
CAS:<p>Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.</p>Fórmula:C24H28N2O9Pureza:97.46%Cor e Forma:SolidPeso molecular:488.49PFI-1
CAS:<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Fórmula:C16H17N3O4SPureza:98.74% - 99.19%Cor e Forma:SolidPeso molecular:347.39MCB-613
CAS:<p>MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.</p>Fórmula:C20H20N2OPureza:98.17% - 99.754%Cor e Forma:SolidPeso molecular:304.39SKLB-163
CAS:<p>SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.</p>Fórmula:C18H16ClN3O2S2Pureza:99.23%Cor e Forma:SolidPeso molecular:405.92Fasentin
CAS:<p>Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.</p>Fórmula:C11H9ClF3NO2Pureza:99.95%Cor e Forma:SolidPeso molecular:279.64Mitoxantrone diacetate
CAS:<p>Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>Fórmula:C26H36N4O10Cor e Forma:SolidPeso molecular:564.592
![[6]-Gingerol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT3405.webp&w=3840&q=75)
