Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6068 products of "Apoptosis"
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CPI1189
CAS:CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.Formula:C13H18N2O2Purity:98.34% - 99.51%Color and Shape:SolidMolecular weight:234.29Betulin
CAS:<p>Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene.</p>Formula:C30H50O2Purity:98.52% - 99.88%Color and Shape:White Crystalline PowderMolecular weight:442.72VER-50589
CAS:VER-50589 is a potent HSP90 inhibitor.Formula:C19H17ClN2O5Purity:99.96% - >99.99%Color and Shape:SolidMolecular weight:388.8Ref: TM-T2258
1mg42.00€5mg97.00€10mg159.00€25mg264.00€50mg404.00€100mg588.00€200mg832.00€1mL*10mM (DMSO)97.00€GSK 3 Inhibitor IX
CAS:<p>GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.</p>Formula:C16H10BrN3O2Purity:98% - 99.72%Color and Shape:SolidMolecular weight:356.17MG 149
CAS:MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).Formula:C22H28O3Purity:98.69% - 99.86%Color and Shape:SolidMolecular weight:340.46Ref: TM-T6584
1mg52.00€2mg74.00€5mg96.00€10mg170.00€25mg324.00€50mg518.00€100mg747.00€1mL*10mM (DMSO)114.00€FR 180204
CAS:FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Formula:C18H13N7Purity:98% - 99.74%Color and Shape:SolidMolecular weight:327.34Ref: TM-T1956
1mg43.00€2mg55.00€5mg86.00€10mg138.00€25mg221.00€50mg331.00€100mg497.00€1mL*10mM (DMSO)94.00€MSC 2032964A
CAS:<p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>Formula:C16H13F3N6OPurity:99.76%Color and Shape:SolidMolecular weight:362.31Ref: TM-T33514
1mg84.00€2mg97.00€5mg158.00€10mg240.00€25mg393.00€50mg560.00€100mg753.00€200mg1,035.00€CHS-828
CAS:CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Formula:C19H22ClN5OPurity:98% - 99.9%Color and Shape:SolidMolecular weight:371.86LW6
CAS:LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formula:C26H29NO5Purity:98.1% - 98.22%Color and Shape:SolidMolecular weight:435.51Ref: TM-T3494
2mg47.00€5mg69.00€10mg89.00€25mg183.00€50mg298.00€100mg449.00€500mg938.00€1mL*10mM (DMSO)69.00€Calycosin
CAS:<p>Calycosin modulates estrogen receptors, induces apoptosis in cancers, and shows skin-lightening by inhibiting tyrosinase (IC50: 38.4µM).</p>Formula:C16H12O5Purity:99.91% - >99.99%Color and Shape:White PowderMolecular weight:284.26Selonsertib
CAS:Selonsertib (GS-4997), an oral ASK1 inhibitor, may have anti-inflammatory, anti-fibrotic, and anti-cancer effects.Formula:C24H24FN7OPurity:95.04% - 99.53%Color and Shape:SolidMolecular weight:445.49Trametinib
CAS:Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Formula:C26H23FIN5O4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:615.39FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Formula:C25H31N3O5S2Purity:99.72% - 99.78%Color and Shape:SolidMolecular weight:517.66Ref: TM-T4066
2mg42.00€5mg63.00€10mg89.00€25mg192.00€50mg341.00€100mg535.00€200mg748.00€1mL*10mM (DMSO)72.00€Volasertib
CAS:Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis.Formula:C34H50N8O3Purity:98% - 99.72%Color and Shape:SolidMolecular weight:618.81Ref: TM-T6019
1mg39.00€2mg52.00€5mg85.00€10mg120.00€25mg215.00€50mg351.00€100mg588.00€1mL*10mM (DMSO)101.00€Triptolide
CAS:Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.Formula:C20H24O6Purity:97.19% - 99.97%Color and Shape:White To Off-White SolidMolecular weight:360.40Ref: TM-T2179
1mg42.00€2mg55.00€5mg90.00€10mg130.00€25mg238.00€50mg334.00€100mg469.00€1mL*10mM (DMSO)80.00€Wogonin
CAS:<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Formula:C16H12O5Purity:98% - 99.8%Color and Shape:Yellow CrystalMolecular weight:284.26Formosanin C
CAS:Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.Formula:C51H82O20Purity:98.98% - >99.99%Color and Shape:SolidMolecular weight:1015.18Cyasterone
CAS:Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFormula:C29H44O8Purity:99.32% - 99.70%Color and Shape:SolidMolecular weight:520.65Stattic
CAS:Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.Formula:C8H5NO4SPurity:98.32% - 99.76%Color and Shape:SolidMolecular weight:211.19Ref: TM-T6308
5mg35.00€10mg51.00€25mg85.00€50mg124.00€100mg187.00€200mg279.00€500mg465.00€1mL*10mM (DMSO)55.00€Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurity:97.71% - >99.99%Color and Shape:SolidMolecular weight:367.3Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Formula:C21H26N6O2Purity:96.01% - ≥98%Color and Shape:SolidMolecular weight:394.47Ref: TM-T6055
1mg59.00€2mg86.00€5mg124.00€10mg180.00€25mg309.00€50mg427.00€100mg605.00€1mL*10mM (DMSO)139.00€α-Hederin
CAS:Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.Formula:C41H66O12Purity:99.44% - 99.89%Color and Shape:SolidMolecular weight:750.96Ref: TM-T3368
1mg37.00€5mg69.00€10mg88.00€25mg144.00€50mg205.00€100mg303.00€200mg445.00€1mL*10mM (DMSO)88.00€BMS-536924
CAS:BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormula:C25H26ClN5O3Purity:99.02%Color and Shape:SolidMolecular weight:479.96Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formula:C15H10O5Purity:98.22% - 99.64%Color and Shape:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMolecular weight:270.24(1E,6E)-Bis(demethoxy)curcumin
CAS:(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formula:C19H16O4Purity:97.45%Color and Shape:SolidMolecular weight:308.33AZ 628
CAS:AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.Formula:C27H25N5O2Purity:99.50%Color and Shape:SolidMolecular weight:451.52SGI-1027
CAS:SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formula:C27H23N7OPurity:99.45% - 99.78%Color and Shape:SolidMolecular weight:461.52Ref: TM-T1904
5mg58.00€10mg94.00€25mg163.00€50mg296.00€100mg467.00€500mg1,035.00€1mL*10mM (DMSO)74.00€Chelidonine
CAS:Chelidonine from Chelidonium majus triggers HeLa cell apoptosis, may reverse MDR, boost chemotherapeutics against leukemia, and inhibit cancer cell metastasis.Formula:C20H19NO5Purity:98% - 99.61%Color and Shape:SolidMolecular weight:353.37RO8994
CAS:RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).Formula:C31H31Cl2FN4O4Purity:99.31% - 99.44%Color and Shape:SolidMolecular weight:613.51Ref: TM-T3517
1mg40.00€2mg52.00€5mg87.00€10mg127.00€25mg230.00€50mg364.00€100mg540.00€1mL*10mM (DMSO)105.00€Tasisulam
CAS:Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.Formula:C11H6BrCl2NO3S2Purity:99% - >99.99%Color and Shape:SolidMolecular weight:415.11Ref: TM-T6191
5mg42.00€10mg62.00€25mg124.00€50mg205.00€100mg305.00€200mg459.00€500mg750.00€1mL*10mM (DMSO)59.00€Rotenone
CAS:Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formula:C23H22O6Purity:89.58% - 99.88%Color and Shape:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Molecular weight:394.42Epibrassinolide
CAS:Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator withFormula:C28H48O6Purity:97.57% - 98.11%Color and Shape:SolidMolecular weight:480.68Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25Goserelin acetate
CAS:<p>Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.</p>Formula:C61H88N18O16Purity:99.77% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:1329.46PIK-75
CAS:<p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>Formula:C16H14BrN5O4SPurity:98.52% - >99.99%Color and Shape:SolidMolecular weight:452.28Pifithrin-β hydrobromide
CAS:Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.Formula:C16H17BrN2SPurity:99.24% - 99.74%Color and Shape:SolidMolecular weight:349.29Levomenol
CAS:<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Formula:C15H26OPurity:96.01%Color and Shape:Clear To Yellowish LiquidMolecular weight:222.37PKR-IN-C16
CAS:PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.Formula:C13H8N4OSPurity:97.8%Color and Shape:SolidMolecular weight:268.29Ref: TM-T16550
1mg43.00€2mg56.00€5mg88.00€10mg137.00€25mg274.00€50mg432.00€100mg638.00€1mL*10mM (DMSO)111.00€Neferine
CAS:Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formula:C38H44N2O6Purity:98.81% - 99.65%Color and Shape:SolidMolecular weight:624.77Momordin Ic
CAS:Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunctionFormula:C41H64O13Purity:98% - 99.69%Color and Shape:SolidMolecular weight:764.94Isoalantolactone
CAS:Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formula:C15H20O2Purity:99.75% - 99.94%Color and Shape:SolidMolecular weight:232.32Zoledronic acid monohydrate
CAS:Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formula:C5H12N2O8P2Purity:99.91%Color and Shape:White To Off-White PowderMolecular weight:290.1Toddaculin
CAS:Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of theFormula:C16H18O4Purity:99.91%Color and Shape:SolidMolecular weight:274.31Sal003
CAS:Sal003, an effective cell-permeable analog, inhibitis the eIF2α phosphatase.Formula:C18H15Cl4N3OSPurity:99.17% - 99.77%Color and Shape:SolidMolecular weight:463.21Ref: TM-T2417
1mg38.00€2mg49.00€5mg73.00€10mg103.00€25mg182.00€50mg270.00€100mg401.00€1mL*10mM (DMSO)74.00€Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Formula:C30H16O8Purity:98.90% - ≥98%Color and Shape:Red-Coloured Anthraquinone-DerivativeMolecular weight:504.44Ref: TM-T6S0923
1mg57.00€5mg127.00€10mg182.00€25mg360.00€50mg532.00€100mg743.00€500mg1,510.00€1mL*10mM (DMSO)140.00€Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formula:C24H25ClFN5O3Purity:98.56% - 99.9%Color and Shape:Off-White SolidMolecular weight:485.94Infigratinib
CAS:<p>Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and</p>Formula:C26H31Cl2N7O3Purity:98% - 98.97%Color and Shape:SolidMolecular weight:560.48Ref: TM-T1975
5mg47.00€10mg60.00€25mg88.00€50mg96.00€100mg153.00€200mg274.00€500mg460.00€1mL*10mM (DMSO)50.00€Salvigenin
CAS:Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formula:C18H16O6Purity:99.17% - 99.78%Color and Shape:SolidMolecular weight:328.32Gardenin B
CAS:<p>Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .</p>Formula:C19H18O7Purity:98.80% - 99.74%Color and Shape:SolidMolecular weight:358.34
