Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(92 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(55 products)
- Calcium Channel(578 products)
- Chloride channel(53 products)
- GABA Receptor(367 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(1 products)
- Na-K-Cl cotransporter(9 products)
- OAT(31 products)
- OCT(7 products)
- P-gp(56 products)
- Potassium Channel(318 products)
- Proton pump(42 products)
- SGLT(32 products)
- Sodium Channel(273 products)
- TRP/TRPV Channel(97 products)
Show 13 more subcategories
Found 2690 products for "Membrane Transporter/Ion Channel".
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NaV1.7 inhibitor-1
CAS:NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).Formula:C23H30FNO4SPurity:99.89%Color and Shape:SolidMolecular weight:435.55Ref: TM-T12181
1mg99.00€5mg241.00€1mL*10mM (DMSO)265.00€10mg385.00€25mg663.00€50mg888.00€100mg1,305.00€VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuitFormula:C20H22ClFN4O2SPurity:98.1%Color and Shape:SolidMolecular weight:436.93Etimizol
CAS:Etimizol improves memory by aiding the consolidation stage, effective against amnesia from hypoxia or brain injury.Formula:C9H14N4O2Purity:99%Color and Shape:White SolidMolecular weight:210.23Prilocaine hydrochloride
CAS:Prilocaine HCl: local amino amide anesthetic, blocks voltage-gated sodium channels in neurons, inhibits Na+ permeability.Formula:C13H21ClN2OPurity:99.97%Color and Shape:SolidMolecular weight:256.77IA-Alkyne
CAS:IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Formula:C8H12INOPurity:99.76%Color and Shape:White SolidMolecular weight:265.09Ref: TM-T15543
1mg56.00€1mL*10mM (DMSO)114.00€5mg119.00€10mg177.00€25mg250.00€50mg313.00€100mg432.00€Nefiracetam
CAS:Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Formula:C14H18N2O2Purity:97.37%Color and Shape:SolidMolecular weight:246.3PSB-12062
CAS:PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).Formula:C19H15NO3SPurity:99.43% - 99.84%Color and Shape:SolidMolecular weight:337.394-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Formula:C5H6N2Purity:91.61%Color and Shape:SolidMolecular weight:94.11Encequidar mesylate
CAS:Encequidar mesylate (HM30181A mesylate) is a competitive P-glycoprotein inhibitor.Formula:C39H40N6O10SPurity:99.84%Color and Shape:SolidMolecular weight:784.83Ref: TM-T11578L
2mg39.00€5mg58.00€1mL*10mM (DMSO)71.00€10mg84.00€25mg146.00€50mg236.00€100mg371.00€500mg845.00€DCPIB
CAS:DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFormula:C22H28Cl2O4Purity:99.79% - 99.87%Color and Shape:SolidMolecular weight:427.36Ref: TM-T10979
2mg39.00€5mg57.00€1mL*10mM (DMSO)63.00€10mg87.00€25mg177.00€50mg301.00€100mg485.00€200mg690.00€Suloctidil
CAS:Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders.Formula:C20H35NOSPurity:99.75% - >99.99%Color and Shape:White SolidMolecular weight:337.56Cinepazide maleate
CAS:Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator.Formula:C22H31N3O5·C4H4O4Purity:99.9% - 99.97%Color and Shape:SolidMolecular weight:533.57Dofequidar fumarate
CAS:Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through theFormula:C34H35N3O7Purity:99.93%Color and Shape:SolidMolecular weight:597.66Ref: TM-T11071
1mg37.00€2mg52.00€5mg80.00€1mL*10mM (DMSO)90.00€10mg118.00€25mg233.00€50mg447.00€100mg650.00€500mg1,369.00€Fluxametamide
CAS:Fluxametamide, an isoxazoline insecticide, targets insect chloride channels with IC50s of 1.95 nM (GABA) and 225 nM (glutamate).Formula:C20H16Cl2F3N3O3Purity:99.49%Color and Shape:SolidMolecular weight:474.26Carboxyamidotriazole Orotate
CAS:Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signalingFormula:C22H16Cl3N7O6Purity:99.37%Color and Shape:SolidMolecular weight:580.763,4,5-Trimethoxycinnamic acid
CAS:3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at theFormula:C12H14O5Purity:98.91%Color and Shape:SolidMolecular weight:238.24Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formula:C11H15NO5Purity:99.96%Color and Shape:White SolidMolecular weight:241.24γ-Aminobutyric acid
CAS:γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.Formula:C4H9NO2Purity:99.95%Color and Shape:White SolidMolecular weight:103.12Bemegride
CAS:Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.Formula:C8H13NO2Purity:99.89%Color and Shape:SolidMolecular weight:155.19Indapamide
CAS:Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Formula:C16H16ClN3O3SPurity:98.97% - 99.83%Color and Shape:SolidMolecular weight:365.83Flumazenil
CAS:Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervousFormula:C15H14FN3O3Purity:99.72% - 99.98%Color and Shape:White SolidMolecular weight:303.29Riparin III
CAS:Riparin III is an alcamide isolated from Aniba riparia that has exhibited effects of antidepressant and anxiolytic activities in acute stress behavioral models.Formula:C16H17NO4Purity:95.97%Color and Shape:White SolidMolecular weight:287.31Cycloleucine
CAS:Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.Formula:C6H11NO2Purity:99.90%Color and Shape:SolidMolecular weight:129.16ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Formula:C19H15FN2OPurity:99.98% - 99.98%Color and Shape:SolidMolecular weight:306.33Ref: TM-T67917
5mg50.00€1mL*10mM (DMSO)50.00€10mg74.00€25mg114.00€50mg156.00€100mg219.00€200mg298.00€ML418
CAS:ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Formula:C19H24ClN3O3Purity:99.3%Color and Shape:SolidMolecular weight:377.87Ref: TM-T16110
1mg37.00€5mg79.00€1mL*10mM (DMSO)84.00€10mg111.00€25mg178.00€50mg288.00€100mg414.00€200mg583.00€Eleclazine hydrochloride
CAS:Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Formula:C21H17ClF3N3O3Purity:99.86%Color and Shape:SolidMolecular weight:451.83Ref: TM-T15207
1mg58.00€5mg110.00€1mL*10mM (DMSO)122.00€10mg166.00€25mg268.00€50mg403.00€100mg532.00€200mg705.00€Bupivacaine hydrochloride
CAS:Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Formula:C18H28N2O·HClPurity:99.89% - 99.9%Color and Shape:White SolidMolecular weight:324.89Manidipine dihydrochloride
CAS:Manidipine dihydrochloride (Manidipine 2HCl) is a potent calcium channel blocker for Ca2+ current(IC50=2.6 nM).Formula:C35H40Cl2N4O6Purity:99.76% - 99.86%Color and Shape:SolidMolecular weight:683.62Lotilaner
CAS:Lotilaner is a parasiticide.Formula:C20H14Cl3F6N3O3SPurity:99.56%Color and Shape:SolidMolecular weight:596.76Ref: TM-T15775
1mg42.00€2mg55.00€5mg89.00€1mL*10mM (DMSO)105.00€10mg137.00€25mg318.00€50mg522.00€100mg835.00€200mg1,125.00€Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formula:C12H10ClN2NaO5SPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:352.73Dooku1
CAS:Dooku1, Yoda1 analog, blocks Piezo1 channels, halting Ca2+ entry. IC50: 1.3μM in HEK 293, 1.5μM in HUVEC, stops Yoda1's aortic relaxation.Formula:C13H9Cl2N3OSPurity:98.87% - 99.74%Color and Shape:SolidMolecular weight:326.2Ref: TM-T11076
1mg43.00€2mg56.00€1mL*10mM (DMSO)90.00€5mg93.00€10mg133.00€25mg259.00€50mg482.00€100mg695.00€BMS-195270
CAS:BMS-195270 is a bio-active chemical.Formula:C15H9ClF3N3O2Purity:98.7%Color and Shape:SolidMolecular weight:355.7Flavoxate hydrochloride
CAS:Flavoxate hydrochloride (DW61) , a muscarinic AChR antagonist, is used in the therapy of various urinary syndromes and as an antispasmodic.Formula:C24H26ClNO4Purity:99.78%Color and Shape:White SolidMolecular weight:427.92SG-094
CAS:SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.Formula:C30H29NO3Purity:97.06% - 98.80%Color and Shape:Yellow ViscousMolecular weight:451.56Ref: TM-T64365
500mgTo inquire1mg40.00€5mg92.00€1mL*10mM (DMSO)92.00€10mg127.00€25mg250.00€50mg358.00€100mg525.00€Clomethiazole
CAS:Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It has potential for treating convulsive status epilepticus.Formula:C6H8ClNSPurity:99.06%Color and Shape:SolidMolecular weight:161.65Celivarone
CAS:Celivarone is a potassium channel blocker used in the study of arrhythmias, atrial flutter and atrial fibrillation.Formula:C34H47NO4Purity:99.53%Color and Shape:SolidMolecular weight:533.74AZD 7009
CAS:AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.Formula:C23H34N4O5Purity:98.42% - 98.51%Color and Shape:White OilMolecular weight:446.54VU0134992 hydrochloride
CAS:VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).Formula:C20H32BrClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:447.84T16Ainh-A01
CAS:T16Ainh-A01 is a potent TMEM16A chloride channel inhibitor with a 1 μM IC50, targeting CaCC.Formula:C19H20N4O3S2Purity:97.18% - 98.15%Color and Shape:SolidMolecular weight:416.52NS3623
CAS:NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Formula:C15H10BrF3N6OPurity:97.06%Color and Shape:SolidMolecular weight:427.18Trichlormethiazide
CAS:Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics.Formula:C8H8Cl3N3O4S2Purity:98.8% - 99.54%Color and Shape:White SolidMolecular weight:380.66Dibucaine
CAS:Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.Formula:C20H29N3O2Purity:99.69% - 99.88%Color and Shape:White SolidMolecular weight:343.46Pramocaine hydrochloride
CAS:Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.Formula:C17H27NO3·HClPurity:99.15% - 99.61%Color and Shape:SolidMolecular weight:329.86Otilonium bromide
CAS:Otilonium bromide (SP63) , an antimuscarinic, is utilized as a spasmolytic agent.Formula:C29H43BrN2O4Purity:99.78% - 99.88%Color and Shape:SolidMolecular weight:563.57Phenibut
CAS:Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).Formula:C10H13NO2Purity:99.55%Color and Shape:White SolidMolecular weight:179.22DMT1 blocker 2
CAS:Compound 12f, a DMT1 blocker, inhibits DMT1 with a 0.83 IC50, potentially blocking intestinal iron absorption.Formula:C16H13N3OPurity:99.68%Color and Shape:SolidMolecular weight:263.29Ref: TM-T11064
1mg71.00€5mg155.00€1mL*10mM (DMSO)203.00€10mg222.00€25mg404.00€50mg607.00€100mg888.00€NS13001
CAS:NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Formula:C17H16ClN7Purity:99.55%Color and Shape:White SolidMolecular weight:353.81Omeprazole sulfide
CAS:Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.Formula:C17H19N3O2SPurity:98.83%Color and Shape:White SolidMolecular weight:329.42Baclofen
CAS:Baclofen (Lioresal), a chlorophenyl-butanoic acid derivative, treats spasms from spinal cord injury and MS by mimicking GABA at GABA-B receptors.Formula:C10H12ClNO2Purity:98% - 99.94%Color and Shape:White SolidMolecular weight:213.66Butamben
CAS:Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.Formula:C11H15NO2Purity:99.43%Color and Shape:SolidMolecular weight:193.24
