Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 302 products of "Potassium Channel"
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Halothane
CAS:Halothane (Anestan) 可以减弱内皮依赖性舒张作用。Formula:C2HBrClF3Purity:99.80% - >99.99%Color and Shape:Colorless Volatile Liquid Density 1 875 G / Cm3 Boiling Point 122 4°F (50 2°C) NoncombustibleMolecular weight:197.38Ropivacaine
CAS:Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Formula:C17H26N2OPurity:97.75% - >99.99%Color and Shape:SolidMolecular weight:274.40NS5806
CAS:NS5806 activates K+ currents, slows KV4.2/4.3 decay with KChIP2, and boosts KV4.3/KChIP2 peaks (EC50=5.3μM).Formula:C16H8Br2F6N6OPurity:97.95%Color and Shape:SolidMolecular weight:574.07AZD 7009
CAS:AZD 7009 is a novel antiarrhythmic compound that inhibits the sodium current of hNav1.5 in CHO K1 cells with an IC50 of 11 uM.Formula:C23H34N4O5Purity:98.42% - 98.51%Color and Shape:SoildMolecular weight:446.54Minoxidil
CAS:Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.Formula:C9H15N5OPurity:99.885% - >99.99%Color and Shape:Crystals From Methanol-Acetonitrile SolidMolecular weight:209.25BMS-394136
CAS:BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.Formula:C24H21Cl2FN4OPurity:98.59% - 99.95%Color and Shape:SolidMolecular weight:471.35Bupivacaine hydrochloride
CAS:Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Formula:C18H28N2O·HClPurity:99.89% - 99.9%Color and Shape:SolidMolecular weight:324.89DCEBIO
CAS:DCEBIO, a 1-EBIO derivative, enhances Cl- secretion via hIK1 K+ channel and apical conductance in T84 cells.
Formula:C9H8Cl2N2OPurity:99.89%Color and Shape:SolidMolecular weight:231.08VU591
CAS:VU591 is a selective extra-renal potassium channel inhibitor with an IC₅₀ of 0.24 μM.Formula:C16H12N6O5Purity:99.29% - 99.53%Color and Shape:SolidMolecular weight:368.3Ref: TM-T13320L
5mg48.00€10mg75.00€25mg133.00€50mg230.00€100mg344.00€500mg740.00€1mL*10mM (DMSO)49.00€4-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Formula:C5H6N2Purity:91.61%Color and Shape:SolidMolecular weight:94.11VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit
Formula:C20H22ClFN4O2SPurity:98.1%Color and Shape:SoildMolecular weight:436.93Tolbutamide
CAS:Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.Formula:C12H18N2O3SPurity:99.80% - 99.93%Color and Shape:White Crystalline PowderMolecular weight:270.35Butamben
CAS:Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.Formula:C11H15NO2Purity:99.43%Color and Shape:Crystals From Alc Physical Description Yellow Powder Insoluble In Water (Ntp 1992)Molecular weight:193.24Quinine
CAS:Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.Formula:C20H24N2O2Purity:99.93% - 99.97%Color and Shape:White Solid PowderMolecular weight:324.42Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formula:C23H28ClN3O7Purity:99.28% - >99.99%Color and Shape:Bright Yellow-Orange Amorphous Solid Crystalline YellowMolecular weight:493.94Quinidine hydrochloride monohydrate
CAS:Quinidine hydrochloride monohydrate is an optical isomer of quinine. Quinidine prolongs cellular action potential and decreases automaticity.Formula:C20H27ClN2O3Purity:94.4% - 99.68%Color and Shape:SolidMolecular weight:378.89NS8593 hydrochloride
CAS:NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .Formula:C17H18ClN3Purity:99.77%Color and Shape:SolidMolecular weight:299.8Ref: TM-T12256
1mg43.00€2mg56.00€5mg88.00€10mg150.00€25mg333.00€50mg497.00€100mg717.00€1mL*10mM (DMSO)92.00€Hydrochlorothiazide
CAS:Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药，可抑制转化 TGF-β/Smad 信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。Formula:C7H8ClN3O4S2Purity:99.43% - 99.50%Color and Shape:Crystals Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:297.74NS19504
CAS:NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 µM.Formula:C10H9BrN2SPurity:99.87%Color and Shape:SolidMolecular weight:269.16Ref: TM-T12255
5mg50.00€10mg84.00€25mg166.00€50mg280.00€100mg420.00€500mg888.00€1mL*10mM (DMSO)52.00€Cloperastine hydrochloride
CAS:Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.Formula:C20H25Cl2NOPurity:97.74% - 99.42%Color and Shape:SolidMolecular weight:366.33Tertiapin-Q
CAS:Tertiapin-Q is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner, inhibiting efflux to K(+).Formula:C106H175N35O24S4Purity:98.06% - 98.09%Color and Shape:SolidMolecular weight:2452Repaglinide
CAS:Repaglinide, a benzoic acid derivative, stimulates insulin, treats type 2 diabetes, and may rarely cause acute liver injury.Formula:C27H36N2O4Purity:99.73% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:452.59Linoleoyl glycine
CAS:Linoleoyl glycine activates hKCNQ1/hKCNE1 channels, has analgesic properties, and is found in skin, spinal cord, and brain.
Formula:C20H35NO3Purity:98.96%Color and Shape:SolidMolecular weight:337.5Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:339.36Terfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Formula:C32H41NO2Purity:98.76% - 99.75%Color and Shape:SolidMolecular weight:471.67BMS-191095
CAS:BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.Formula:C22H21ClN4O2Purity:>99.99%Color and Shape:SolidMolecular weight:408.88Ref: TM-T10566
1mg92.00€5mg192.00€10mg289.00€25mg522.00€50mg708.00€100mg954.00€1mL*10mM (DMSO)212.00€ICA-27243
CAS:ICA-27243: Potent KCNQ2/Q3 opener, oral, EC50 0.38 μM; less effective on KCNQ4, KCNQ3/Q5; antiepileptic.Formula:C12H7ClF2N2OPurity:99.54%Color and Shape:SolidMolecular weight:268.65VU591 hydrochloride
CAS:VU591 hydrochloride is a selective Kir1.1 (ROMK) blocker with IC50 of 0.24 μM, not affecting Kir7.1, Kir2.1, Kir2.3, or Kir4.1, similar to VU 590.Formula:C16H13ClN6O5Purity:98.93% - 99.22%Color and Shape:SolidMolecular weight:404.76Ref: TM-T13320
1mg34.00€5mg71.00€10mg105.00€25mg215.00€50mg366.00€100mg512.00€200mg695.00€1mL*10mM (DMSO)79.00€N-Acetylprocainamide
CAS:N-Acetylprocainamide (NAPA), the N-acetylated metabolite of Procainamide, is a Class III antiarrhythmic agent, while procainamide is a Class Ia antiarrhythmicFormula:C15H23N3O2Purity:99.65% - 99.74%Color and Shape:SolidMolecular weight:277.36Propafenone
CAS:Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.Formula:C21H27NO3Purity:99.02%Color and Shape:SolidMolecular weight:341.44Ropivacaine hydrochloride
CAS:Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activityFormula:C17H26N2O·HClPurity:99.85% - 99.95%Color and Shape:SolidMolecular weight:310.86Oxybutynin
CAS:Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.Formula:C22H31NO3Purity:97.81% - 99.57%Color and Shape:White To Off-White Crystalline PowderMolecular weight:357.49Gliclazide
CAS:Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of theFormula:C15H21N3O3SPurity:99.58%Color and Shape:SolidMolecular weight:323.41Dequalinium chloride
CAS:Dequalinium chloride: topical bacteriostat, blocks apamin-sensitive K+ channels, used for wounds, oral infections, potential antifungal, risk of skin ulcers.
Formula:C30H40Cl2N4Purity:99.79% - 99.9%Color and Shape:SolidMolecular weight:527.59Astemizole
CAS:Astemizole (Laridal) is a long-acting antihistamine for allergies like rhinitis and asthma, with fewer anticholinergic effects.Formula:C28H31FN4OPurity:98.24% - 99.67%Color and Shape:White Crystals SolidMolecular weight:458.57Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.
Formula:C17H16F6N2OPurity:99.89%Color and Shape:SolidMolecular weight:378.31Diazoxide
CAS:Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.Formula:C8H7ClN2O2SPurity:99% - 99.83%Color and Shape:SolidMolecular weight:230.67Oxybutynin chloride
CAS:Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties.Formula:C22H32ClNO3Purity:99.27% - >99.99%Color and Shape:White PowderMolecular weight:393.96Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Formula:C14H10F3NO2Purity:98.68%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:281.23Proflavine Hemisulfate
CAS:Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt of proflavine, an acridine-derived fluorescent contrast and disinfectant agent.Formula:C13H12N3O2S0Purity:99.55%Color and Shape:Orange To Red PowderMolecular weight:258.291-EBIO
CAS:1-EBIO (1-EBIO) is a calium channel agonist.Formula:C9H10N2OPurity:98.75%Color and Shape:SolidMolecular weight:162.19Rosuvastatin calcium
CAS:Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemicFormula:(C22H27FN3O6S)CaPurity:98.21% - 99.68%Color and Shape:White To Off-White Crystalline SolidMolecular weight:1001.14Nicorandil
CAS:Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system.Formula:C8H9N3O4Purity:98.14% - >99.99%Color and Shape:White Or Off-White PowderMolecular weight:211.17Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Formula:C21H29N3OPurity:99.62%Color and Shape:SolidMolecular weight:339.47Glipizide
CAS:Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.Formula:C21H27N5O4SPurity:99.67% - 99.75%Color and Shape:SolidMolecular weight:445.54Indapamide
CAS:Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Formula:C16H16ClN3O3SPurity:98.97% - 99.83%Color and Shape:SolidMolecular weight:365.83Linopirdine
CAS:Linopirdine (DuP 996) is a TRPV1 agonist.Formula:C26H21N3OPurity:99.45% - 99.78%Color and Shape:SolidMolecular weight:391.46Ref: TM-T15758
1mg40.00€2mg52.00€5mg84.00€10mg119.00€25mg215.00€50mg371.00€100mg532.00€200mg767.00€500mg1,144.00€1mL*10mM (DMSO)93.00€NS3623
CAS:NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Formula:C15H10BrF3N6OPurity:97.06%Color and Shape:SolidMolecular weight:427.18Tipepidine hydrochloride
CAS:Tipepidine hydrochloride: reversible DA D2 receptor inhibitor, IC50 7.0 μM, with antidepressant effects.Formula:C15H18ClNS2Purity:99.97%Color and Shape:SolidMolecular weight:311.89NS13001
CAS:NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Formula:C17H16ClN7Purity:99.55%Color and Shape:SolidMolecular weight:353.81Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurity:99% - 99.99%Color and Shape:Off-White To Yellow SolidMolecular weight:414.77Brompheniramine maleate
CAS:Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.Formula:C16H19BrN2·C4H4O4Purity:99.80%Color and Shape:Crystal PowderMolecular weight:435.31Dronedarone hydrochloride
CAS:Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5S·HClPurity:99.61%Color and Shape:SolidMolecular weight:593.22Ref: TM-T1073
5mg38.00€10mg52.00€25mg87.00€50mg117.00€100mg170.00€200mg250.00€500mg424.00€1mL*10mM (DMSO)55.00€DCPIB
CAS:DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFormula:C22H28Cl2O4Purity:99.79% - 99.87%Color and Shape:SolidMolecular weight:427.36Ref: TM-T10979
2mg39.00€5mg57.00€10mg87.00€25mg177.00€50mg301.00€100mg485.00€200mg690.00€1mL*10mM (DMSO)63.00€Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurity:99.05% - 99.75%Color and Shape:SolidMolecular weight:494.00VU0134992 hydrochloride
CAS:VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 μM).Formula:C20H32BrClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:447.84Ifenprodil Tartrate
CAS:Ifenprodil is a selective NMDA receptor (glutamate) antagonist.Formula:C21H27NO2C4H6O6Purity:99.02% - 99.55%Color and Shape:SolidMolecular weight:400.49Amiodarone hydrochloride
CAS:Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.Formula:C25H29I2NO3·HClPurity:99.82% - ≥95%Color and Shape:White To Cream Crystalline PowderMolecular weight:681.78IK1 inhibitor PA-6
CAS:IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFormula:C31H32N4O2Purity:98.9%Color and Shape:SolidMolecular weight:492.61Clofilium tosylate
CAS:Clofilium tosylate is a potassium channel blocker, induces apoptosis on human promyelocytic leukemia (HL-60) cells.Formula:C28H44ClNO3SPurity:99.68% - >99.99%Color and Shape:SolidMolecular weight:510.17Eleclazine hydrochloride
CAS:Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Formula:C21H17ClF3N3O3Purity:99.86%Color and Shape:SolidMolecular weight:451.83Ref: TM-T15207
1mg58.00€5mg110.00€10mg166.00€25mg268.00€50mg403.00€100mg532.00€200mg705.00€1mL*10mM (DMSO)122.00€Tannic acid
CAS:Tannic acid (Gallotannic acid) is a novel hERG channel blocker.Formula:C76H52O46Purity:AR - ARColor and Shape:Light Yellow To Light Brown Solid Solid Particulate/PowderMolecular weight:1701.2Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formula:C22H22FN3O3Purity:99.19% - 99.73%Color and Shape:SolidMolecular weight:395.43Flindokalner
CAS:Flindokalner (BMS-204352) modulates potassium channels, enhances Kv7 subtypes and BKca, inhibits Kv7.1 (Ki=3.7μM), GABAA; has anxiolytic effects in vivo.Formula:C16H10ClF4NO2Purity:99.96%Color and Shape:SolidMolecular weight:359.7ML418
CAS:ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Formula:C19H24ClN3O3Purity:99.3%Color and Shape:SolidMolecular weight:377.87Ref: TM-T16110
1mg37.00€5mg79.00€10mg111.00€25mg178.00€50mg288.00€100mg414.00€200mg583.00€1mL*10mM (DMSO)88.00€Doxapram hydrochloride hydrate
CAS:Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.Formula:C24H33ClN2O3C24H30N2O2·ClH·H2OPurity:99.64% - >99.99%Color and Shape:SolidMolecular weight:432.99Apamin
CAS:Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.Formula:C79H131N31O24S4Purity:98%Color and Shape:SolidMolecular weight:2027.34Margatoxin
CAS:KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx & NO in endothelial cells.Formula:C178H286N52O50S7Purity:98%Color and Shape:SolidMolecular weight:4178.96Charybdotoxin
CAS:Specific inhibitor of the big conductance Ca2+-activated K+ channel.Formula:C176H277N57O55S7Purity:98%Color and Shape:SolidMolecular weight:4295.95Aam-KTX
Aam-KTX, a toxic peptide sourced from Mesobuthus eupeus scorpion venom, acts as a selective K_v channel inhibitor, exhibiting IC_50 values of 1.1 nM for K_v1.3Formula:C174H288N58O48S7Purity:98%Color and Shape:SolidMolecular weight:4184.96Tamapin TFA
Tamapin TFA, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small conductance Ca(2+)-activated KFormula:C146H238N44O41S6·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3458.11 (free base)AmmTX3 TFA
AmmTX3 TFA, a peptide toxin derived from Androctonus mauretanicus scorpion venom, functions as a selective blocker of the K_v4 channel.Formula:C158H262N50O48S6·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3822.47 (free acid)Hongotoxin-1
Hongotoxin-1, a chemical compound isolated from the venom of Centruroides limbatus, functions as a potassium channel inhibitor.Formula:C181H299N53O49S7Purity:98%Color and Shape:SolidMolecular weight:4226.13Vm24-toxin
CAS:Vm24-toxin, a peptide toxin isolated from the Mexican scorpion Vaejovis mexicanus smithi, serves as an inhibitor of the Kv1.3 potassium channel [1].Formula:C157H253N51O45S9Purity:98%Color and Shape:SolidMolecular weight:3863.59Stromatoxin 1
CAS:Stromatoxin 1, a peptide isolated from tarantulas, acts as an inhibitor of various potassium channels, including K(V)2.1, K(V)2.2, K(V)4.2, and K(V)2.1/9.3.Formula:C156H237N49O48S7Purity:98%Color and Shape:SolidMolecular weight:3791.31HsTX1
CAS:HsTX1, a 34-residue, C-terminally amidated peptide isolated from the scorpion Heterometrus spinnifer, features four disulfide bridges and acts as a potassiumFormula:C149H246N54O46S9Purity:98%Color and Shape:SolidMolecular weight:3818.47Tamapin
Tamapin, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus) [1], selectively targets and blocks small-conductance Ca(2+)-activated KFormula:C146H238N44O41S6Purity:98%Color and Shape:SolidMolecular weight:3458.11Iberiotoxin TFA
Iberiotoxin (TFA) is a selective inhibitor of high conductance Ca2+-activated K+ channels, exhibiting a dissociation constant (Kd) of approximately 1 nM, yet itFormula:C179H274N50O55S7·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:4230.85 (free base)Spinoxin
CAS:Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges.Formula:C147H236N48O46S9Purity:98%Color and Shape:SolidMolecular weight:3700.33Jingzhaotoxin-X
Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1].Formula:C164H242N46O41S6Purity:98%Color and Shape:SolidMolecular weight:3706.35Ssm spooky toxin
Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through theFormula:C270H413N69O79S4Purity:98%Color and Shape:SolidMolecular weight:6017.84ShK toxin
CAS:ShK toxin, isolated from the Caribbean sea anemone (Stichodactyla helianthus), is an inhibitor of the voltage-dependent potassium channel (Kv1.3 channel).Formula:C169H274N54O48S7Purity:98%Color and Shape:SolidMolecular weight:4054.8Dendrotoxin K
CAS:Dendrotoxin K blocks Kv1.1 channels, modulating glutamate release in CA3 neurons by controlling presynaptic spike timing.Formula:C294H462N84O75S6Color and Shape:SolidMolecular weight:6559.66δ-Dendrotoxin
CAS:δ-Dendrotoxin is a potassium (K+) channel blocker derived from black mamba snake venom and is utilized in neurological disease research [1].Formula:C296H452N82O76S6Purity:98%Color and Shape:SolidMolecular weight:6567.65Iberiotoxin
CAS:Selective blocker of the big conductance Ca2+-activated K+ channel.Formula:C179H274N50O55S7Purity:98%Color and Shape:SolidMolecular weight:4230ADWX 1
Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.Formula:C169H281N57O46S7Purity:98%Color and Shape:SolidMolecular weight:4071.86BmP02
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2Formula:C115H182N36O41S7Purity:98%Color and Shape:SolidMolecular weight:2949.35Noxiustoxin
CAS:Noxiustoxin, a toxin extracted from the venom of the Mexican scorpion Centruroides noxius, inhibits both the voltage-dependent potassium channel (Kv1.3, IC50 =Formula:C174H286N52O54S7Purity:98%Color and Shape:SolidMolecular weight:4195Pandinotoxin Kα
CAS:Pandinotoxin Kα, a chemical compound extracted from the emperor scorpion (Pandinus imperator) venom, functions as an inhibitor of the A-type potassium channel [Formula:C169H267N53O48S7Purity:98%Color and Shape:SolidMolecular weight:4033.71Tertiapin-RQ
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].Formula:C106H175N37O25S4Purity:98%Color and Shape:SolidMolecular weight:2496.02Tertiapin LQ
Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.Formula:C106H179N33O24S4Purity:98%Color and Shape:SolidMolecular weight:2428.03Jingzhaotoxin-XII TFA
Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.Color and Shape:Odour SolidBDS-I
CAS:BDS-I, a marine toxin derived from Anemonia sulcata, functions as a selective inhibitor of the potassium channel, specifically targeting Kv3.4.Formula:C210H297N57O56S6Purity:98%Color and Shape:SolidMolecular weight:4708.346-FAM-AEEAC-SHK TFA
6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.Formula:C196H295N55O57S7·xCHF3O2Color and Shape:SolidMolecular weight:4558.23 (free acid)Aekatperone
Aekatperone, a reversible KATP channel inhibitor, exhibits an IC50 of 9 μM. It is utilized in research related to congenital hyperinsulinism (CHI).Formula:C20H25N5O2SColor and Shape:SolidMolecular weight:399.51Hemitoxin
Hemitoxin, a scorpion-venom peptide, functions as a K+ channel blocker and selectively inhibits rat Kv1.1, Kv1.2, and Kv1.3 channels expressed in XenopusFormula:C159H259N49O49S8Purity:98%Color and Shape:SolidMolecular weight:3897.58GsAF-I
GsAF-I is a potent blocker of Na_v and hERG1 channels, exhibiting half-maximal inhibitory concentrations (IC50s) of 0.36 μM (Na_v 1.1), 0.6 μM (Na_v 1.2), 1.28Formula:C160H244N46O42S7Purity:98%Color and Shape:SolidMolecular weight:3708.39Heteropodatoxin-2
CAS:Heteropodatoxin-2, a 30-amino acid peptide, inhibits the Kv4.2 current in Xenopus laevis oocytes through a voltage-dependent mechanism, exhibiting reducedFormula:C144H207N39O46S6Purity:98%Color and Shape:SolidMolecular weight:3412.81Tertiapin-Q acetate
Tertiapin-Q acetate is a bee toxin derivative that inhibits BK-type K(+) channels in a concentration-dependent manner.Formula:C108H179N35O26S4Purity:96.44%Color and Shape:SolidMolecular weight:2512.06Phe-Met-Arg-Phe amide trifluoroacetate
CAS:Phe-met-arg-phe amide trifluoroacetate is an activator of K+ current with an ED50 of 23nm on the fundus nerve.Formula:C33H44F6N8O8SPurity:98%Color and Shape:SolidMolecular weight:826.81
