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Neuroscience

Neuroscience

Neuroscience inhibitors are compounds designed to modulate the activity of specific proteins, enzymes, or receptors within the nervous system. These inhibitors are crucial for studying the molecular mechanisms underlying neural function, synaptic transmission, and neurodegenerative diseases. By targeting neurotransmitter receptors, ion channels, and signaling pathways, neuroscience inhibitors aid in the exploration of brain function and the development of therapeutic strategies for neurological disorders such as Alzheimer's, Parkinson's, and epilepsy. At CymitQuimica, we offer a comprehensive range of high-quality neuroscience inhibitors to support your research in neurobiology, neuropharmacology, and cognitive sciences.

Subcategories of "Neuroscience"

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Found 5398 products of "Neuroscience"

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  • 5-AAM-2-CP

    CAS:
    <p>5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.</p>
    Formula:C8H9ClN2O
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:184.62
  • Fluphenazine-N-2-chloroethane (hydrochloride)

    CAS:
    <p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>
    Formula:C22H27Cl3F3N3S
    Color and Shape:Solid
    Molecular weight:528.89
  • CPN-351

    CAS:
    <p>CPN-351 (compound 9a) is a pentapeptide that acts as a selective antagonist for human NMUR1, with a pA2 value of 7.35. It exhibits ten times greater antagonistic activity toward human NMUR1 compared to NMUR2. CPN-351 is applicable in inflammation research.</p>
    Formula:C45H61N13O6S
    Molecular weight:912.11
  • BTMPS

    CAS:
    <p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>
    Formula:C28H52N2O4
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:480.72
  • Tiaspirone hydrochloride

    CAS:
    <p>Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.</p>
    Formula:C24H33ClN4O2S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:477.06
  • 5-HT6R antagonist 6


    <p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>
    Formula:C24H26N4O2S
    Color and Shape:Solid
    Molecular weight:434.55
  • (S)-AMPA HCl


    <p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>
    Formula:C7H11ClN2O4
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:222.63
  • CDD0102 HCl

    CAS:
    <p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>
    Formula:C8H13ClN4O
    Purity:99.7%
    Color and Shape:Soild
    Molecular weight:216.67
  • Antipsychotic agent-2


    <p>Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.</p>
    Formula:C22H26FN5O
    Color and Shape:Solid
    Molecular weight:395.47
  • Tryptamine hydrochloride

    CAS:
    <p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>
    Formula:C10H13ClN2
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:196.68
  • ACHE Inhibitor 12

    CAS:
    <p>ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.</p>
    Formula:C11H12O
    Purity:98.71%
    Color and Shape:Solid
    Molecular weight:160.21
  • Amyloid-Forming peptide GNNQQNY

    CAS:
    <p>Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental in</p>
    Formula:C33H48N12O14
    Color and Shape:Solid
    Molecular weight:836.81
  • LtIA-F


    <p>LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.</p>
    Formula:C86H121N25O22S4
    Color and Shape:Solid
    Molecular weight:1985.31
  • FITC-β-Ala-Amyloid β-Protein (1-42)

    CAS:
    <p>FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.</p>
    Formula:C227H327N57O66S2
    Molecular weight:4971.34251
  • Anagyrine hydrochloride

    CAS:
    <p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>
    Formula:C15H21ClN2O
    Color and Shape:Solid
    Molecular weight:280.79
  • GABAA receptor modulator-3


    <p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>
    Formula:C18H22O2
    Color and Shape:Solid
    Molecular weight:270.37
  • XL01126


    <p>XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.</p>
    Formula:C50H64ClFN10O6S2
    Color and Shape:Solid
    Molecular weight:1019.69
  • Feralolide

    CAS:
    <p>Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and</p>
    Formula:C18H16O7
    Color and Shape:Solid
    Molecular weight:344.32
  • AChE-IN-45


    <p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>
    Color and Shape:Odour Solid
  • LU-32-176B

    CAS:
    <p>LU32-176B is a bioactive chemical.</p>
    Formula:C23H24F2N2O2
    Color and Shape:Solid
    Molecular weight:398.45
  • SQ-3


    <p>SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]</p>
    Formula:C21H21FN2O
    Color and Shape:Solid
    Molecular weight:336.4
  • Br-PBTC

    CAS:
    <p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>
    Formula:C14H15BrN2OS
    Color and Shape:Solid
    Molecular weight:339.25
  • Chrysophanol-1-O-β-gentiobioside

    CAS:
    <p>Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozyme</p>
    Formula:C27H30O14
    Color and Shape:Solid
    Molecular weight:578.52
  • BIBD-124

    CAS:
    <p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>
    Formula:C19H24FN3O3
    Color and Shape:Solid
    Molecular weight:361.41
  • Bencycloquidium Bromide

    CAS:
    <p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>
    Formula:C21H32BrNO2
    Color and Shape:Solid
    Molecular weight:410.39
  • CHF-5022

    CAS:
    <p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>
    Formula:C17H12F4O2
    Color and Shape:Solid
    Molecular weight:324.27
  • N-Methylcyclohexaneethaneamine

    CAS:
    <p>N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences.</p>
    Formula:C9H19N
    Color and Shape:Solid
    Molecular weight:141.2539
  • JH-XII-03-02

    CAS:
    <p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>
    Formula:C43H51N9O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:853.92
  • Hydroxytacrine maleate

    CAS:
    <p>Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).</p>
    Formula:C17H18N2O5
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:330.34
  • Muscarine

    CAS:
    <p>Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>
    Formula:C9H20NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:174.26
  • Withasomniferolide B

    CAS:
    <p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>
    Formula:C28H36O4
    Color and Shape:Solid
    Molecular weight:436.58
  • Methoxy-X04

    CAS:
    <p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>
    Formula:C23H20O3
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:344.4
  • hAChE-IN-6


    <p>hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM.</p>
    Color and Shape:Odour Solid
  • Cytidine 5′-diphosphoethanolamine

    CAS:
    <p>Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].</p>
    Formula:C11H20N4O11P2
    Color and Shape:Solid
    Molecular weight:446.24
  • BuChE-IN-11


    <p>BuChE-IN-11 (Compound 3b-1) is a selective inhibitor of BuChE with an IC50 of 0.44 μM for hBuChE. The compound demonstrates high brain-blood barrier permeability and possesses free radical scavenging capabilities, indicating significant antioxidant activity. BuChE-IN-11 interacts with the choline binding site, the acyl binding site, and the peripheral anionic site, showing submicromolar inhibitory activity against BuChE and preventing the self-aggregation of β-amyloid protein (Aβ). This compound holds promise for research in the field of Alzheimer's disease.</p>
    Formula:C28H27FN4O2
    Molecular weight:470.2118
  • Antidepressant agent 3


    <p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>
    Formula:C17H30ClN5O2S
    Color and Shape:Solid
    Molecular weight:403.97
  • BSB

    CAS:
    <p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>
    Formula:C24H17BrO6
    Purity:95.53%
    Color and Shape:Solid
    Molecular weight:481.29
  • BuChE-IN-8


    <p>BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) and</p>
    Formula:C28H33ClN4O2S
    Color and Shape:Solid
    Molecular weight:525.11
  • Zanapezil free base

    CAS:
    <p>Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.</p>
    Formula:C25H32N2O
    Color and Shape:Solid
    Molecular weight:376.544
  • FFN246

    CAS:
    <p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>
    Formula:C15H13FN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:256.27
  • β-Amyloid (33-40)

    CAS:
    <p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>
    Formula:C32H58N8O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:730.92
  • Bensultap

    CAS:
    <p>Bensultap is an agricultural chemical typically used as a pesticide.</p>
    Formula:C17H21NO4S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:431.61
  • R-(+)-Cotinine

    CAS:
    <p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>
    Formula:C10H12N2O
    Color and Shape:Solid
    Molecular weight:176.22
  • Peptide 401

    CAS:
    <p>Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.</p>
    Formula:C110H192N40O24S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2587.22
  • Heliosupine N-oxide


    <p>Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.</p>
    Formula:C20H31NO8
    Color and Shape:Solid
    Molecular weight:413.467
  • Epiboxidine hydrochloride

    CAS:
    <p>Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.</p>
    Formula:C10H15ClN2O
    Color and Shape:Solid
    Molecular weight:214.69
  • JNJ-67569762

    CAS:
    <p>JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).</p>
    Formula:C22H22F4N4O5S
    Color and Shape:Solid
    Molecular weight:530.49
  • AChE-IN-70


    <p>AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.</p>
    Color and Shape:Odour Solid
  • Velnacrine

    CAS:
    <p>Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.</p>
    Formula:C13H14N2O
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:214.26
  • Calmodulin-Dependent Protein Kinase II (281-309)

    CAS:
    <p>Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).</p>
    Formula:C146H254N46O39S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3374.06
  • PF-03382792

    CAS:
    <p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>
    Formula:C23H32FN3O4
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:433.52
  • Fezolamine

    CAS:
    <p>Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.</p>
    Formula:C20H23N3
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:305.42
  • Binospirone

    CAS:
    <p>Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.</p>
    Formula:C20H26N2O4
    Purity:97.57% - 98.96%
    Color and Shape:Soild
    Molecular weight:358.43
  • Malaoxon

    CAS:
    <p>Malaoxon is used as an insecticide.</p>
    Formula:C10H19O7PS
    Color and Shape:Solid
    Molecular weight:314.29
  • PSEN1-IN-1


    <p>PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50</p>
    Formula:C20H19ClF3NO3S
    Color and Shape:Solid
    Molecular weight:445.88
  • Anisatin


    <p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>
    Formula:C15H20O8
    Color and Shape:Solid
    Molecular weight:328.317
  • CNS-Penetrant Compound Library


    <p>A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);</p>
    Color and Shape:Odour Solid
  • 1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-

    CAS:
    <p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>
    Formula:C10H12N2O2S
    Purity:99.96%
    Color and Shape:Soild
    Molecular weight:224.28
  • Neuronal Signaling Compound Library


    <p>A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>
    Color and Shape:Odour Solid
  • AC3-I, myristoylated


    <p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>
    Formula:C78H137N21O20
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1689.05
  • RBPJ Inhibitor-1

    CAS:
    <p>RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cell</p>
    Formula:C17H14FN3O2
    Purity:99.58%
    Color and Shape:Soild
    Molecular weight:311.31
  • BACE1-IN-6

    CAS:
    <p>BACE1-IN-6 is a BACE1 inhibitor with an IC 50 value of 1.5 nM.</p>
    Formula:C25H23F2N5O2S
    Color and Shape:Solid
    Molecular weight:495.55
  • Org 13011

    CAS:
    <p>Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.</p>
    Formula:C18H25F3N4O
    Purity:98.02%
    Color and Shape:Soild
    Molecular weight:370.41
  • Guvacine hydrobromide

    CAS:
    <p>Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.</p>
    Formula:C6H10BrNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:208.05
  • (R,R)-Palonosetron Hydrochloride

    CAS:
    <p>(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron</p>
    Formula:C19H25ClN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:332.87
  • (rel)-Asperparaline A

    CAS:
    <p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>
    Formula:C20H29N3O3
    Color and Shape:Solid
    Molecular weight:359.47
  • AChE-IN-40


    <p>AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's disease</p>
    Formula:C23H27NO4
    Color and Shape:Solid
    Molecular weight:381.46
  • (S)-UFR2709 hydrochloride

    CAS:
    <p>(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety &amp; alcohol intake in rats, studies nicotine addiction.</p>
    Formula:C13H18ClNO2
    Purity:98.94%
    Color and Shape:Solid
    Molecular weight:255.74
  • COX-1-IN-2


    <p>COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a significant inhibitory effect on COX-1, with an IC 50 value of 38.76 nM.</p>
    Formula:C29H22FN3OS
    Color and Shape:Solid
    Molecular weight:479.57
  • MmTx1 toxin


    <p>Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].</p>
    Formula:C295H455N95O97S10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:7205
  • CaMKIIα-PHOTAC


    <p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>
    Formula:C54H58Cl2N10O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1094
  • GAD65(247-266) epitope TFA


    <p>GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeit</p>
    Formula:C111H174F3N27O29S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2535.99
  • COX-1/2-IN-5


    <p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>
    Formula:C21H22N2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.47
  • CVN417


    <p>CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.</p>
    Color and Shape:Odour Solid
  • Methyl piperate

    CAS:
    <p>Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition</p>
    Formula:C13H12O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:232.23
  • IHC3


    <p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>
    Formula:C17H12FN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:293.3
  • β-Amyloid (13-27)

    CAS:
    β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.
    Formula:C84H126N24O24
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1856.05
  • MAOA-IN-1


    <p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>
    Formula:C13H16Cl2N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:303.18
  • DCCCyb

    CAS:
    <p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>
    Formula:C22H29Cl2NO3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:458.44
  • 2002-H20

    CAS:
    <p>2002-H20 is an Aβ42-induced cytotoxicity inhibitor. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.</p>
    Formula:C20H15N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:345.358
  • Aβ-IN-7


    <p>Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers</p>
    Formula:C14H10N2S
    Color and Shape:Solid
    Molecular weight:238.31
  • GABA receptor Antagonist 1


    <p>GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.</p>
    Purity:98%
    Color and Shape:Odour Solid
  • Dipentylone hydrochloride

    CAS:
    <p>Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.</p>
    Formula:C14H20ClNO3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:285.77
  • MAO-B-IN-38


    <p>MAO-B-IN-38 (Compound 6b) is a reversible, competitive inhibitor of MAO-B, exhibiting IC50 values of 0.03 µM for MAO-B and 21.46 µM for MAO-A. This compound is applicable in research on neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.</p>
    Formula:C14H17FN4O2S3
    Color and Shape:Solid
    Molecular weight:388.504
  • MmTx2 toxin


    <p>MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists.</p>
    Formula:C295H450N94O97S10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:7185.95
  • Lysyl hydroxylase 2-IN-2


    <p>Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM.</p>
    Formula:C19H21N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:323.39
  • NMDA receptor antagonist 6


    <p>NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective</p>
    Formula:C25H23NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:369.46
  • 5-HT6 agonist 1


    Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet
    Formula:C17H22Cl2N6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:413.37
  • MRS7925


    <p>MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis</p>
    Formula:C20H26IN5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:511.36
  • MAO-B-IN-25


    <p>MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nM</p>
    Formula:C16H13BrO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:333.18
  • LY 344864 racemate

    CAS:
    <p>LY 344864 racemate is a 5-HT1F receptor agonist.</p>
    Formula:C21H22FN3O
    Purity:99.75%
    Color and Shape:Soild
    Molecular weight:351.42
  • 5-AMAM-2-CP

    CAS:
    <p>5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].</p>
    Formula:C9H11ClN2O
    Color and Shape:Solid
    Molecular weight:198.65
  • Emamectin B1a

    CAS:
    <p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>
    Formula:C49H75NO13
    Color and Shape:Solid
    Molecular weight:886.133
  • I2-IRs ligand-1


    <p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>
    Formula:C21H23ClFN2O4P
    Color and Shape:Solid
    Molecular weight:452.84
  • Desmethyl Mirtazapine (hydrochloride)

    CAS:
    <p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>
    Formula:C16H18ClN3
    Color and Shape:Solid
    Molecular weight:287.79
  • AChE-IN-27

    CAS:
    <p>AChE-IN-27 is a small molecule used for high-throughput assays.</p>
    Formula:C20H14N2O3
    Purity:98.54%
    Color and Shape:Solid
    Molecular weight:330.34
  • DDC 2′,3′-O-disulfate


    <p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>
    Formula:C17H16O11S2
    Color and Shape:Solid
    Molecular weight:460.43
  • BMY-14802

    CAS:
    <p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>
    Formula:C18H22F2N4O
    Purity:99.84%
    Color and Shape:Soild
    Molecular weight:348.39
  • Glycerophosphorylethanolamine (sodium salt)

    CAS:
    <p>Glycerophosphorylethanolamine, a phosphatidylethanolamine metabolite, elevates in Alzheimer's and promotes Aβ40 aggregation.</p>
    Formula:C5H13NNaO6P
    Color and Shape:Solid
    Molecular weight:237.12
  • AZD4694 Precursor

    CAS:
    <p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>
    Formula:C22H25N3O7
    Color and Shape:Solid
    Molecular weight:443.45