Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Formula:C24H34N6OPurity:98.46% - 99.56%Color and Shape:SolidMolecular weight:422.57Ref: TM-T17208
1mg42.00€5mg88.00€10mg127.00€25mg250.00€50mg393.00€100mg628.00€500mg1,304.00€1mL*10mM (DMSO)87.00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purity:99.21%Color and Shape:SolidMolecular weight:531.13Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formula:C44H70O16Purity:98% - 99.5%Color and Shape:SolidMolecular weight:855.02JMS-17-2
CAS:JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).Formula:C25H26ClN3OPurity:98.7% - 99.44%Color and Shape:SolidMolecular weight:419.95Ref: TM-T5849
1mg35.00€5mg78.00€10mg117.00€25mg198.00€50mg310.00€100mg460.00€200mg665.00€1mL*10mM (DMSO)87.00€TC14012 acetate
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM.Formula:C92H144N34O21S2Purity:98.33% - 99.71%Color and Shape:SolidMolecular weight:2126.47MSX-130
CAS:MSX-130 is CXCR4 Antagonist.Formula:C36H26N4Purity:99.19%Color and Shape:SolidMolecular weight:514.62SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Formula:C18H23F2N5O4S2Purity:99.65% - 99.92%Color and Shape:SolidMolecular weight:475.53Plerixafor
CAS:Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.Formula:C28H54N8Purity:99.17% - >99.99%Color and Shape:SolidMolecular weight:502.78AZD-5069
CAS:AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).Formula:C18H22F2N4O5S2Purity:98.38% - 98.63%Color and Shape:SolidMolecular weight:476.52Ref: TM-T7681
1mg34.00€2mg47.00€5mg66.00€10mg98.00€25mg190.00€50mg295.00€100mg447.00€200mg623.00€1mL*10mM (DMSO)73.00€Plerixafor octahydrochloride
CAS:Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.Formula:C28H62Cl8N8Purity:98.01% - 99.79%Color and Shape:SolidMolecular weight:794.46SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Formula:C19H14BF4N3O4SPurity:98.19% - 99.61%Color and Shape:SolidMolecular weight:467.2Isobavachalcone
CAS:Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury inFormula:C20H20O4Purity:98% - 99.76%Color and Shape:SolidMolecular weight:324.37HG-10-102-01
CAS:HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).Formula:C17H20ClN5O3Purity:99.59%Color and Shape:SolidMolecular weight:377.83Ref: TM-T7196
2mg35.00€5mg55.00€10mg89.00€25mg161.00€50mg250.00€100mg360.00€200mg512.00€1mL*10mM (DMSO)62.00€Lucanthone
CAS:Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).Formula:C20H24N2OSPurity:99.92%Color and Shape:Yellow Crystals From Alcohol SolidMolecular weight:340.48Ref: TM-T4569
1mg52.00€2mg75.00€5mg119.00€10mg178.00€25mg379.00€50mg560.00€100mg793.00€1mL*10mM (DMSO)133.00€Pennogenin 3-O-β-chacotrioside
CAS:Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.Formula:C45H72O17Purity:99.69% - 99.77%Color and Shape:SolidMolecular weight:885.04RITA
CAS:RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.Formula:C14H12O3S2Purity:98.49% - 99.55%Color and Shape:SolidMolecular weight:292.37Ref: TM-T1798
1mg35.00€5mg66.00€10mg96.00€25mg187.00€50mg279.00€100mg420.00€200mg607.00€1mL*10mM (DMSO)89.00€4EGI-1
CAS:4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formula:C18H12Cl2N4O4SPurity:96.8% - 99.12%Color and Shape:SolidMolecular weight:451.28Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formula:C19H25BN4O4Purity:97.79% - >99.99%Color and Shape:Yellow SolidMolecular weight:384.24Ref: TM-T2399
5mg50.00€10mg60.00€25mg75.00€50mg92.00€100mg137.00€200mg213.00€500mg353.00€1mL*10mM (DMSO)50.00€CZC-25146 hydrochloride
CAS:CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.Formula:C22H26ClFN6O4SPurity:98.76%Color and Shape:SolidMolecular weight:525Danshensu
CAS:Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.Formula:C9H10O5Purity:98.4% - 99.74%Color and Shape:SolidMolecular weight:198.17SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormula:C22H27ClN2O3Purity:99.47% - 99.92%Color and Shape:SolidMolecular weight:402.91Ref: TM-T2170
5mg54.00€10mg81.00€25mg131.00€50mg230.00€100mg445.00€200mg680.00€500mg1,054.00€1mL*10mM (DMSO)59.00€Vitexin
CAS:Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.Formula:C21H20O10Purity:98.13% - 99.64%Color and Shape:Yellow PowderMolecular weight:432.3810074-G5
CAS:10074-G5 is an inhibitor of c-Myc-Max dimerization.Formula:C18H12N4O3Purity:99.51% - 99.94%Color and Shape:SolidMolecular weight:332.31Ref: TM-T3686
2mg39.00€5mg59.00€10mg84.00€25mg135.00€50mg213.00€100mg375.00€200mg535.00€500mg853.00€1mL*10mM (DMSO)65.00€KN-93
CAS:KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formula:C26H29ClN2O4SPurity:99.56% - 99.86%Color and Shape:White SolidMolecular weight:501.04Ref: TM-T2697
1mg54.00€2mg74.00€5mg107.00€10mg146.00€25mg289.00€50mg358.00€100mg523.00€1mL*10mM (DMSO)120.00€Taxifolin
CAS:Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formula:C15H12O7Purity:94.91% - 98.9%Color and Shape:Yellowish PowderMolecular weight:304.25RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurity:99.56%Color and Shape:SolidMolecular weight:518.41Ref: TM-T6296
1mg44.00€2mg59.00€5mg93.00€10mg140.00€25mg253.00€50mg413.00€100mg605.00€1mL*10mM (DMSO)94.00€D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purity:99.99%Color and Shape:White Or Off-White PowderMolecular weight:146.14IU1
CAS:IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂，可以穿透细胞，IC50为 4.7 μM。Formula:C18H21FN2OPurity:98% - 99.3%Color and Shape:SolidMolecular weight:300.37PF-3845
CAS:PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.Formula:C24H23F3N4O2Purity:99.54% - 99.58%Color and Shape:SolidMolecular weight:456.46Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purity:98.75% - 99.57%Color and Shape:SolidMolecular weight:199.25Ref: TM-T4414
5mg70.00€10mg100.00€25mg195.00€50mg349.00€100mg618.00€500mg1,251.00€1mL*10mM (DMSO)77.00€ML-SA1
CAS:ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.Formula:C22H22N2O3Purity:99.34% - 99.71%Color and Shape:SolidMolecular weight:362.42Ref: TM-T23004
2mg34.00€5mg49.00€10mg77.00€25mg142.00€50mg230.00€100mg344.00€200mg520.00€1mL*10mM (DMSO)55.00€Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Formula:C18H14N2O4Purity:95.85% - 99.22%Color and Shape:SolidMolecular weight:322.31Ref: TM-T1848
5mg49.00€10mg79.00€25mg140.00€50mg259.00€100mg374.00€200mg560.00€500mg883.00€1mL*10mM (DMSO)87.00€NH125
CAS:NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formula:C27H45IN2Purity:98.60%Color and Shape:SolidMolecular weight:524.56Ref: TM-T6605
1mg40.00€2mg52.00€5mg88.00€10mg119.00€25mg264.00€50mg454.00€100mg655.00€1mL*10mM (DMSO)87.00€CX546
CAS:CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.Formula:C14H17NO3Purity:99.75%Color and Shape:SolidMolecular weight:247.295-Aminolevulinic acid hydrochloride
CAS:5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.Formula:C5H10ClNO3Purity:98% - 99.97%Color and Shape:White To Pale Yellow Crystals OrMolecular weight:167.59Ulipristal acetate
CAS:Ulipristal acetate (CDB-2914) is an oral selective progesterone modulator used for emergency contraception and suppressing uterine growths.Formula:C30H37NO4Purity:98.83% - 99.94%Color and Shape:SolidMolecular weight:475.62Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Formula:C40H57N5O7Purity:99.6% - 99.84%Color and Shape:SolidMolecular weight:719.91Nidufexor
CAS:Nidufexor is an agonist for the farnesoid X receptor (FXR).Formula:C27H22ClN3O4Purity:98.67%Color and Shape:SolidMolecular weight:487.93Ref: TM-T4S0797
5mgTo inquire10mgTo inquire25mgTo inquire50mg93.00€100mg125.00€500mg266.00€1mL*10mM (DMSO)55.00€Ginkgetin
CAS:Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.Formula:C32H22O10Purity:98.63% - 99.94%Color and Shape:SolidMolecular weight:566.51Ref: TM-T4S2126
1mg46.00€5mg92.00€10mg146.00€25mg250.00€50mg369.00€100mg545.00€200mg777.00€1mL*10mM (DMSO)114.00€Rilmenidine Phosphate
CAS:Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Formula:C10H19N2O5PPurity:99.99% - ≥95%Color and Shape:SolidMolecular weight:278.24Ref: TM-T6641
1mg34.00€5mg67.00€10mg93.00€25mg152.00€50mg230.00€100mg363.00€200mg528.00€1mL*10mM (DMSO)67.00€Metformin
CAS:Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formula:C4H11N5Purity:99.77% - >99.99%Color and Shape:SolidMolecular weight:129.16Ref: TM-T8526
10mg44.00€25mg66.00€50mg93.00€100mg102.00€500mg250.00€2500mg414.00€1mL*10mM (DMSO)44.00€Indomethacin farnesil
CAS:Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.Formula:C34H40ClNO4Purity:97.29%Color and Shape:SolidMolecular weight:562.14SB 202190
CAS:SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formula:C20H14FN3OPurity:98% - 99.84%Color and Shape:Pale YellowMolecular weight:331.34CaMKII-IN-1
CAS:CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).Formula:C29H30ClN5O2SPurity:99.69%Color and Shape:SolidMolecular weight:548.1Ref: TM-T14860
1mg50.00€2mg71.00€5mg113.00€10mg166.00€25mg334.00€50mg520.00€100mg750.00€1mL*10mM (DMSO)137.00€Dihydromyricetin
CAS:Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Formula:C15H12O8Purity:96.68% - 98.229%Color and Shape:SolidMolecular weight:320.25MHY1485
CAS:MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.Formula:C17H21N7O4Purity:97.74% - >99.99%Color and Shape:SolidMolecular weight:387.39(-)-Epicatechin gallate
CAS:(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.Formula:C22H18O10Purity:99.16% - 99.93%Color and Shape:SolidMolecular weight:442.371-Monomyristin
CAS:1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterialFormula:C17H34O4Purity:99.58%Color and Shape:SolidMolecular weight:302.45Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formula:C33H40O15Purity:97.82% - 98.3%Color and Shape:SolidMolecular weight:676.66CFTR(inh)-172
CAS:CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.Formula:C18H10F3NO3S2Purity:98% - 99.72%Color and Shape:SolidMolecular weight:409.4Ref: TM-T2355
1mg34.00€2mg43.00€5mg63.00€10mg92.00€25mg178.00€50mg340.00€100mg502.00€1mL*10mM (DMSO)65.00€Syringin
CAS:Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.Formula:C17H24O9Purity:98.89% - 99.96%Color and Shape:SolidMolecular weight:372.37VER-155008
CAS:VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.
Formula:C25H23Cl2N7O4Purity:97.03% - 99.55%Color and Shape:SolidMolecular weight:556.4Pitavastatin calcium
CAS:Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Formula:C50H46CaF2N2O8Purity:98.89% - >99.99%Color and Shape:White To Off-White PowderMolecular weight:880.98Tarenflurbil
CAS:Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.Formula:C15H13FO2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:244.26Efavirenz
CAS:Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.Formula:C14H9ClF3NO2Purity:99.2% - 99.84%Color and Shape:White To Slightly Pink Crystalline PowderMolecular weight:315.67Ref: TM-T2393
1g383.00€5mg39.00€10mg50.00€25mg67.00€50mg85.00€100mg110.00€500mg259.00€1mL*10mM (DMSO)50.00€D4476
CAS:D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Formula:C23H18N4O3Purity:99.7% - 99.96%Color and Shape:SolidMolecular weight:398.41Dactolisib
CAS:Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).
Formula:C30H23N5OPurity:97.64% - 99.85%Color and Shape:SolidMolecular weight:469.54Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurity:99.74%Color and Shape:Leaves From Petroleum Ether; White-Brown Scales SolidMolecular weight:131.17MW-150
CAS:MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.Formula:C24H23N5Purity:97.35% - 99.27%Color and Shape:SolidMolecular weight:381.47Ref: TM-T5494
1mg37.00€5mg90.00€10mg144.00€25mg289.00€50mg430.00€100mg620.00€500mg1,333.00€1mL*10mM (DMSO)108.00€Lumefantrine
CAS:Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.Formula:C30H32Cl3NOPurity:98.36%Color and Shape:Yellow SolidMolecular weight:528.94Shogaol
CAS:6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.Formula:C17H24O3Purity:98.26% - 99.93%Color and Shape:SolidMolecular weight:276.37Ref: TM-T6S1699
2mg40.00€5mg58.00€10mg96.00€25mg170.00€50mg268.00€100mg409.00€500mg888.00€1mL*10mM (DMSO)64.00€Dapivirine
CAS:Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formula:C20H19N5Purity:98% - 99.77%Color and Shape:SolidMolecular weight:329.4Irinotecan
CAS:Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.Formula:C33H38N4O6Purity:98% - 99.92%Color and Shape:SolidMolecular weight:586.68LY2109761
CAS:LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.Formula:C26H27N5O2Purity:97% - 99.83%Color and Shape:SolidMolecular weight:441.52Ref: TM-T2123
2mg44.00€5mg66.00€10mg105.00€25mg178.00€50mg318.00€100mg480.00€200mg692.00€1mL*10mM (DMSO)73.00€trifarotene
CAS:Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.
Formula:C29H33NO4Purity:99.51%Color and Shape:SolidMolecular weight:459.58Melatonin
CAS:Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.Formula:C13H16N2O2Purity:98% - 99.89%Color and Shape:Pale Yellow Leaflets From Benzene SolidMolecular weight:232.28Peiminine
CAS:1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
Formula:C27H43NO3Purity:99.52% - ≥95%Color and Shape:White PowderMolecular weight:429.64Ridaforolimus
CAS:Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。Formula:C53H84NO14PPurity:90.00% - 98.55%Color and Shape:Off-White SolidMolecular weight:990.21Oroxylin A
CAS:Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formula:C16H12O5Purity:98.72% - 99.55%Color and Shape:SolidMolecular weight:284.26Ref: TM-T6S1315
1mg37.00€5mg71.00€10mg90.00€25mg147.00€50mg208.00€100mg309.00€200mg447.00€1mL*10mM (DMSO)84.00€SBI-0640756
CAS:SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Formula:C23H14ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:404.82Enzalutamide
CAS:Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).Formula:C21H16F4N4O2SPurity:99% - 99.93%Color and Shape:SolidMolecular weight:464.44Ref: TM-T6002
5mg48.00€10mg56.00€25mg74.00€50mg96.00€100mg154.00€200mg187.00€500mg274.00€1mL*10mM (DMSO)52.00€Arctigenin
CAS:(-)-Arctigenin ((-)-Arctigenin) is found in burdock.Formula:C21H24O6Purity:98% - 99.51%Color and Shape:SolidMolecular weight:372.41PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Ref: TM-T6954
5mg49.00€10mg70.00€25mg133.00€50mg195.00€100mg349.00€200mg518.00€500mg830.00€1mL*10mM (DMSO)54.00€Fexaramine
CAS:Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.Formula:C32H36N2O3Purity:98.87% - 99.61%Color and Shape:SolidMolecular weight:496.64GSK2656157
CAS:GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.Formula:C23H21FN6OPurity:98.59% - >99.99%Color and Shape:SolidMolecular weight:416.45Ref: TM-T2654
2mg34.00€5mg52.00€10mg77.00€25mg135.00€50mg245.00€100mg442.00€200mg598.00€1mL*10mM (DMSO)52.00€PD-166866
CAS:PD-166866 is a selective FGFR tyrosine kinase inhibitor.Formula:C20H24N6O3Purity:98.29%Color and Shape:SolidMolecular weight:396.44ICCB-19 hydrochloride
CAS:ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Formula:C12H22ClN3OSPurity:99.3%Color and Shape:SolidMolecular weight:291.84Ref: TM-T8931L
5mg34.00€10mg50.00€25mg90.00€50mg138.00€100mg198.00€200mg296.00€500mg469.00€1mL*10mM (DMSO)34.00€Pictilisib
CAS:Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Formula:C23H27N7O3S2Purity:98.69% - 99.97%Color and Shape:SolidMolecular weight:513.64SF1670
CAS:SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.Formula:C19H17NO3Purity:98.25% - 98.54%Color and Shape:SolidMolecular weight:307.34Ref: TM-T6667
1mg42.00€2mg52.00€5mg94.00€10mg118.00€25mg259.00€50mg475.00€100mg702.00€1mL*10mM (DMSO)92.00€Thiamet G
CAS:Thiamet G is a selective O-GlcNAcase inhibitor (Ki=20 nM). The role of O-GlcNAcase is to remove O-GlcNAc from the modified protein. High-Quality, Low-Cost!Formula:C9H16N2O4SPurity:99.06% - 99.98%Color and Shape:SolidMolecular weight:248.3Ref: TM-T6056
2mg42.00€5mg59.00€10mg87.00€25mg178.00€50mg324.00€100mg484.00€500mg1,071.00€1mL*10mM (DMSO)59.00€Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Formula:C22H34O7Purity:98.83% - 99.96%Color and Shape:Less Crystalline Solid Colorless Crystalline SolidMolecular weight:410.50Ref: TM-T2939
5mg40.00€10mg56.00€25mg86.00€50mg96.00€100mg144.00€200mg182.00€500mg306.00€1mL*10mM (DMSO)56.00€6-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formula:C5H5N5SPurity:98.75% - >99.99%Color and Shape:Odorless Or Almost Odorless Pale Yellow Crystalline PowderMolecular weight:167.19Calcineurin substrate acetate
Calcineurin substrate acetate is from the regulatory RII subunit of cAMP-dependent protein kinase.Formula:C94H154N28O31Purity:97.59%Color and Shape:SolidMolecular weight:2172.4Cinobufagin
CAS:Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.Formula:C26H34O6Purity:97.77% - 99.97%Color and Shape:SolidMolecular weight:442.54Ref: TM-T3432
1mg49.00€5mg90.00€10mg137.00€25mg203.00€50mg281.00€100mg439.00€500mg954.00€1mL*10mM (DMSO)90.00€Fludrocortisone acetate
CAS:Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormula:C23H31FO6Purity:96.92% - 98.03%Color and Shape:Crystalline SolidMolecular weight:422.49Vinblastine sulfate
CAS:Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).Formula:C46H58N4O9·H2SO4Purity:97.81% - 99.82%Color and Shape:White PowderMolecular weight:909.06Tacrolimus
CAS:Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent proteinFormula:C44H69NO12Purity:98% - 99.94%Color and Shape:White Or Off-White Crystalline PowderMolecular weight:804.02Ref: TM-T6S1784
1mg34.00€5mg71.00€10mg92.00€25mg148.00€50mg212.00€100mg318.00€200mg470.00€1mL*10mM (DMSO)77.00€Glycycoumarin
CAS:Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.Formula:C21H20O6Purity:97.64% - 99.78%Color and Shape:SolidMolecular weight:368.38Ref: TM-TN1702
1mg39.00€5mg77.00€10mg115.00€25mg222.00€50mg329.00€100mg489.00€200mg705.00€1mL*10mM (DMSO)85.00€PTC-209
CAS:PTC-209 is a potent and selective BMI-1 inhibitor.Formula:C17H13Br2N5OSPurity:99.43% - 99.887%Color and Shape:SolidMolecular weight:495.19S29434
CAS:S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).Formula:C21H18N4O3Purity:99.92%Color and Shape:SolidMolecular weight:374.39PH-797804
CAS:PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.Formula:C22H19BrF2N2O3Purity:97.90% - 98.27%Color and Shape:SolidMolecular weight:477.3Ref: TM-T1974
1mg43.00€5mg88.00€10mg137.00€25mg241.00€50mg385.00€100mg595.00€500mg1,251.00€1mL*10mM (DMSO)92.00€Isradipine
CAS:Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.Formula:C19H21N3O5Purity:99.84% - 99.95%Color and Shape:Yellow SolidMolecular weight:371.39AM580
CAS:AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )Formula:C22H25NO3Purity:98% - 99.84%Color and Shape:SolidMolecular weight:351.44Ref: TM-T5854
2mg37.00€5mg54.00€10mg82.00€25mg156.00€50mg299.00€100mg444.00€500mg1,009.00€1mL*10mM (DMSO)60.00€Bakuchiol
CAS:Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.Formula:C18H24OPurity:98.04% - 99.05%Color and Shape:Brownish Yellow Liquid ViscousMolecular weight:256.38IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Formula:C28H29N5OSPurity:98.76% - 99.61%Color and Shape:SolidMolecular weight:483.63Ref: TM-T6176
1mg38.00€2mg50.00€5mg84.00€10mg132.00€25mg233.00€50mg385.00€100mg550.00€200mg782.00€1mL*10mM (DMSO)93.00€NL-1
CAS:NL-1 is a mitoNEET inhibitor with antileukemic effect.Formula:C18H25NO3SPurity:98.64%Color and Shape:SolidMolecular weight:335.46JH-II-127
CAS:JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).Formula:C19H21ClN6O3Purity:98.32%Color and Shape:SolidMolecular weight:416.86Ref: TM-T7155
2mg43.00€5mg66.00€10mg96.00€25mg166.00€50mg259.00€100mg366.00€200mg520.00€1mL*10mM (DMSO)73.00€Ruxolitinib
CAS:Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formula:C17H18N6Purity:99.4% - >99.99%Color and Shape:SolidMolecular weight:306.36Ref: TM-T1829
5mg55.00€10mg71.00€25mg96.00€50mg110.00€100mg146.00€200mg231.00€500mg393.00€1mL*10mM (DMSO)62.00€
