GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

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Found 5378 products of "GPCR/G-Protein"

Purity (%)

100

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ANXA3 degrader 1
ANXA3 degrader 1 (Compound 18a5) is a highly selective ANXA3 degrader with activity against cancer cells. It demonstrates significant inhibitory effects in a triple-negative breast cancer (TNBC) tumor xenograft model, with a tumor growth inhibition (TGI) rate of 96%.
Formula:C₃₀H₃₂N₆O₂S₂
Color and Shape:Solid
Molecular weight:572.74
Ref: TM-T205558
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[Sar9] Substance P
CAS:
- 77128-75-7
[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
Formula:C₆₄H₁₀₀N₁₈O₁₃S
Purity:98%
Color and Shape:Solid
Molecular weight:1361.66
Ref: TM-TP1862
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Dexbrompheniramine maleate
CAS:
- 2391-03-9
Dexbrompheniramine is an antihistamine used for hay fever and urticaria, blocking H1 receptors in the body.
Formula:C₂₀H₂₃BrN₂O₄
Color and Shape:Solid
Molecular weight:435.318
Ref: TM-T31396
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17-trifluoromethylphenyl trinor Prostaglandin F2α
CAS:
- 221246-34-0
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.
Formula:C₂₄H₃₁F₃O₅
Color and Shape:Solid
Molecular weight:456.502
Ref: TM-T37946
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Pasireotide ditrifluoroacetate
Pasireotide is a stable cyclohexapeptide somatostatin mimic.
Formula:C₆₂H₆₈F₆N₁₀O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1275.25
Ref: TM-T13811
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2-Furoyl-LIGRLO-amide
CAS:
- 729589-58-6
2-Furoyl-LIGRLO-amide TFA is a peptide that acts as a proteinase-activated receptor-2 (PAR2) agonist, and contains a furoyl group addition at its N-terminal.
Formula:C₃₆H₆₃N₁₁O₈
Purity:98%
Color and Shape:Solid
Molecular weight:777.95
Ref: TM-TP1478
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1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid
CAS:
- 50264-63-6
1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. It acts as an MRGPRX4 antagonist with an IC50 greater than 2.5 μM.
Formula:C₁₅H₁₁FN₂O₂
Color and Shape:Solid
Molecular weight:270.26
Ref: TM-T203147
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19(R)-hydroxy Prostaglandin E1
CAS:
- 64625-55-4
19(R)-hydroxy Prostaglandin E1 is an agonist of EP1 and EP3 receptor subtypes and exhibits contractile activity on smooth muscle and is the major prostaglandin
Formula:C₂₀H₃₄O₆
Color and Shape:Solid
Molecular weight:370.486
Ref: TM-T37778
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S 16474
CAS:
- 149250-10-2
S 16474 is an antagonist of Neurokinin-1 Receptor.
Formula:C₄₄H₄₈N₆NaO₈
Purity:98%
Color and Shape:Solid
Molecular weight:811.892
Ref: TM-T26169
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Detomidine carboxylic acid
CAS:
- 115664-39-6
Detomidine carboxylic acid, a urine metabolite of detomidine, is a synthetic α2-agonist, animal analgesic, with cardiac, respiratory, and diuretic effects.
Formula:C₁₂H₁₂N₂O₂
Purity:98%
Color and Shape:Solid
Molecular weight:216.24
Ref: TM-T11010
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PACAP-38 (16-38), human, mouse, rat
CAS:
- 144025-82-1
PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production
Formula:C₁₂₃H₂₁₅N₃₉O₂₈S
Purity:98%
Color and Shape:Solid
Molecular weight:2720.33
Ref: TM-TP1619
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NF157
CAS:
- 104869-26-3
NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.
Formula:C₄₉H₂₈F₂N₆Na₆O₂₃S₆
Purity:98%
Color and Shape:Solid
Molecular weight:1437.1
Ref: TM-T16291
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17-phenyl trinor Prostaglandin F2α cyclopropyl amide
CAS:
- 1138395-12-6
17-phenyl trinor Prostaglandin F2α cyclopropyl amide (17-phenyl trinor PGF2α cyclopropyl amide) is a novel analog of 17-phenyl trinor PGF2α ethyl amide.
Formula:C₂₆H₃₇NO₄
Color and Shape:Solid
Molecular weight:427.585
Ref: TM-T37940
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Vanicoside E
CAS:
- 208707-91-9
Vanicoside E is an antioxidant and antitumor agent. Vanicoside E inhibits L-Tyrosine and L-DOPA with IC 50 s of 45.23 μM and 189.96 μM, respectively [1] [2] .
Formula:C₅₃H₅₂O₂₂
Color and Shape:Solid
Molecular weight:1040.97
Ref: TM-T75563
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FK 224
CAS:
- 125787-94-2
FK 224 is an antagonist of tachykinin receptor.
Formula:C₅₄H₇₂N₈O₁₃
Color and Shape:Solid
Molecular weight:1041.213
Ref: TM-T25419
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SKF-83566 hydrochloride
CAS:
- 164265-49-0
SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.
Formula:C₁₇H₁₉BrClNO
Purity:99.27%
Color and Shape:Soild
Molecular weight:368.69
Ref: TM-T8702L
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(R)-Citalopram oxalate
CAS:
- 219861-53-7
(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant
Formula:C₂₂H₂₃FN₂O₅
Purity:99.76%
Color and Shape:White Solid
Molecular weight:414.43
Ref: TM-T6493L
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Pafenolol
CAS:
- 75949-61-0
Pafenolol is a P-glycoprotein modulator with a Ki value of 5.5 µM. pafenolol is an orally available and selective beta-adrenergic receptor antagonist.
Formula:C₁₈H₃₁N₃O₃
Purity:98.33%
Color and Shape:Solid
Molecular weight:337.46
Ref: TM-T68124
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Survodutide
CAS:
- 2805997-46-8
Survodutide (BI 456906) is a dual agonist of glucagon and glucagon-like peptide 1 (GLP-1) receptor (GLP Receptor) that reduces body weight in HbA1c16 diabetes.
Formula:C₁₉₂H₂₈₉N₄₇O₆₁
Purity:99.83%
Color and Shape:Solid
Molecular weight:4229.0957
Ref: TM-T76559
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Oxmetidine FA
Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.
Formula:C₂₀H₂₃N₅O₅S
Purity:97.34%
Color and Shape:Soild
Molecular weight:445.49
Ref: TM-T68122L
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Upidosin
CAS:
- 152735-23-4
Upidosin (SB-216469), a uroselective α1 blocker: Ki α1a=0.34 nM, α1b=3.9 nM, α1d=1.5 nM, α2=33.3 nM.
Formula:C₃₁H₃₃N₃O₄
Purity:99.66%
Color and Shape:Solid
Molecular weight:511.61
Ref: TM-T9762
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IRL-1038 TFA
IRL-1038 TFA is an ETB receptor antagonist used in the study of cardiovascular disease.
Formula:C₇₀H₉₃F₃N₁₄O₁₇S₂
Purity:98.79%
Color and Shape:Solid
Molecular weight:1523.7
Ref: TM-TP2262L1
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SR-140603
CAS:
- 154728-59-3
SR-140603, the less potent enantiomer of SR 140333, is used as the negative control.
Formula:C₃₇H₄₅Cl₃N₂O₂
Purity:98%
Color and Shape:Solid
Molecular weight:656.12
Ref: TM-T26222
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MEN 11270
CAS:
- 235082-52-7
B2 bradykinin receptor peptide antagonist, pKi 10.3; improves hypotension, bronchoconstriction; B2-selective over 29 receptors/ion channels.
Formula:C₆₀H₉₀N₂₀O₁₁S
Purity:98%
Color and Shape:Solid
Molecular weight:1299.56
Ref: TM-TP1999
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Tetrahydro-β-carboline
CAS:
- 16502-01-5
Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
Formula:C₁₁H₁₂N₂
Purity:96.31%
Color and Shape:Tan Solid
Molecular weight:172.2264
Ref: TM-Fr12161
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Tabernanthalog
CAS:
- 2483829-58-7
TBG is a 5-HT2A agonist reducing alcohol/heroin cravings and promoting neuroplasticity with antidepressant effects in rodents.
Formula:C₁₄H₁₈N₂O
Purity:99.82% - 99.89%
Color and Shape:Soild
Molecular weight:230.31
Ref: TM-T60221
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SR 142948 dihydrochloride
SR 142948 dihydrochloride is a selective oral non-peptide NT antagonist, IC50 <4 nM, with brain penetration and potential for psychiatric research.
Formula:C₃₉H₅₃Cl₂N₅O₆
Color and Shape:Solid
Molecular weight:758.77
Ref: TM-T73677
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W140 HBr
CAS:
- 1246817-25-3
[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide is a S1P1 antagonist with Ki of 2.84 μM.
Formula:C₁₆H₂₈BrN₂O₄P
Purity:99.85%
Color and Shape:Soild
Molecular weight:423.28
Ref: TM-T60204
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Men 10208
CAS:
- 129781-07-3
Men 10208 is an antagonist of the neurokinin A receptor.
Formula:C₆₁H₇₅N₁₅O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1210.36
Ref: TM-T24447
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Cianopramine hydrochloride
CAS:
- 66834-20-6
Cianopramine hydrochloride is a bio-active chemical.
Formula:C₂₀H₂₄ClN₃
Color and Shape:Solid
Molecular weight:341.88
Ref: TM-T30929
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Colulintide
CAS:
- 2891912-36-8
Colulintide is an analog of amylin, utilized in obesity research.
Color and Shape:Solid
Ref: TM-TP3252
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Apelin-36(rat, mouse)
CAS:
- 230299-95-3
Endogenous APJ agonist from adipocytes; binds APJ tightly, inhibits cAMP, regulates heart function and fluid balance, blocks some HIV strains.
Formula:C₁₈₅H₃₀₄N₆₈O₄₃S
Purity:98%
Color and Shape:Solid
Molecular weight:4200.93
Ref: TM-TP2094
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LY 293284
CAS:
- 141318-62-9
LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.
Formula:C₁₉H₂₆N₂O
Color and Shape:Solid
Molecular weight:298.42
Ref: TM-T27914
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13,14-dihydro-15-keto Prostaglandin F1α
CAS:
- 29044-75-5
13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach.
Formula:C₂₀H₃₆O₅
Color and Shape:Solid
Molecular weight:356.5
Ref: TM-T36148
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Tafluprost acid
CAS:
- 209860-88-8
Tafluprost acid is a selective agonist at the prostaglandin F receptor.
Formula:C₂₂H₂₈F₂O₅
Color and Shape:Solid
Molecular weight:410.46
Ref: TM-T20142
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Cholecystokinin Octapeptide, desulfated
CAS:
- 25679-24-7
Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, non-sulfated) is an octapeptide composed of 8 amino acids from cholecystokinin-8.
Formula:C₄₉H₆₂N₁₀O₁₃S₂
Purity:97.12%
Color and Shape:Solid
Molecular weight:1063.21
Ref: TM-TP2204
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IRL-1620 acetate
IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.
Formula:C₈₈H₁₂₁N₁₇O₂₉
Purity:96.64%
Color and Shape:Solid
Molecular weight:1881
Ref: TM-T15595L
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Dehydro Aripiprazole (hydrochloride)
CAS:
- 1008531-60-9
Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.
Formula:C₂₃H₂₆Cl₃N₃O₂
Color and Shape:Solid
Molecular weight:482.83
Ref: TM-T36664
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BQ-123 TFA
BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.
Formula:C₃₃H₄₃F₃N₆O₉
Color and Shape:Solid
Molecular weight:724.72
Ref: TM-T73877
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Samelisant
CAS:
- 1394808-82-2
Samelisant (SUVN-G3031), a selective H3 inverse agonist, Ki=8.7/9.8 nM in humans/rats, has anti-narcoleptic properties.
Formula:C₂₁H₃₁N₃O₃
Purity:99.59%
Color and Shape:Solid
Molecular weight:373.49
Ref: TM-T9770
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AC-264613
CAS:
- 1051487-82-1
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613 suppresses interferon regulatory factor 5.
Formula:C₁₉H₁₈BrN₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:400.28
Ref: TM-T4186
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Jatrorrhizine hydroxide
CAS:
- 483-43-2
Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.
Formula:C₂₀H₂₁NO₅
Color and Shape:Solid
Molecular weight:355.38
Ref: TM-T75436
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Lysophosphatidic acid
CAS:
- 22002-87-5
Lysophosphatidic acid is a bioactive chemical.
Formula:C₂₁H₄₁O₇P
Color and Shape:Solid
Molecular weight:436.52
Ref: TM-T33076
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Linzagolix choline
CAS:
- 1321816-57-2
Linzagolix choline is a GnRH antagonist. It can be used to study pain associated with uterine fibroids and endometriosis.
Formula:C₂₇H₂₈F₃N₃O₈S
Purity:99.64%
Color and Shape:Solid
Molecular weight:611.59
Ref: TM-T25742
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H4R antagonist 3
CAS:
- 1003091-20-0
H4R antagonist 3 is a novel histamine-4 receptor (H4R) antagonist with an EC50 <10 mM.H4R antagonist 3 has potential inflammatory activity for the study of
Formula:C₁₉H₂₁ClN₄S
Purity:98%
Color and Shape:Solid
Molecular weight:372.92
Ref: TM-T77715
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FSLLRY-NH2
CAS:
- 245329-02-6
PAR2 antagonist; counters taxol effects, PKC in mice; inhibits ERK, collagen in fibroblasts; lessens dermatophyte itch in mice.
Formula:C₃₉H₆₀N₁₀O₈
Purity:98%
Color and Shape:Solid
Molecular weight:796.97
Ref: TM-TP1904
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Blue FPG-A trisodium
CAS:
- 78617-94-4
Blue FPG-A trisodium is a P2X1 & P2Y1 receptor antagonist, IC50: 35.5 μM & 2.6 μM, related to RB2.
Formula:C₂₉H₁₇ClN₇Na₃O₁₁S₃
Color and Shape:Solid
Molecular weight:840.1
Ref: TM-T75347
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Alcaftadine carboxylic acid
CAS:
- 147083-93-0
Alcaftadine is a novel antihistamine for preventing allergic conjunctivitis.
Formula:C₁₉H₂₁N₃O₂
Color and Shape:Solid
Molecular weight:323.39
Ref: TM-T25033
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ACTH (1-14)
CAS:
- 25696-21-3
ACTH (1-14) is a pituitary hormone fragment that controls cortisol and androgen levels.
Formula:C₇₇H₁₀₉N₂₁O₂₀S
Purity:98%
Color and Shape:Solid
Molecular weight:1680.88
Ref: TM-TP1238
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ECPLA
CAS:
- 2349367-50-4
ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.
Formula:C₂₁H₂₅N₃O
Color and Shape:Solid
Molecular weight:335.44
Ref: TM-T203569
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Benzomalvin B
CAS:
- 157047-97-7
Benzomalvin B, a metabolite from Penicillium, blocks 24% NK1 receptor binding at 100 μg/ml.
Formula:C₂₄H₁₇N₃O₂
Color and Shape:Solid
Molecular weight:379.419
Ref: TM-T38033
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Desmethyl Mirtazapine (hydrochloride)
CAS:
- 1188265-41-9
Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.
Formula:C₁₆H₁₈ClN₃
Color and Shape:Solid
Molecular weight:287.79
Ref: TM-T37352
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Thiothixene
CAS:
- 5591-45-7
Thiothixene has a wide range of applications in life science related research.
Formula:C₂₃H₂₉N₃O₂S₂
Color and Shape:Solid
Molecular weight:443.62
Ref: TM-T38200
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SB 258585
CAS:
- 209480-63-7
SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.
Formula:C₁₈H₂₂IN₃O₃S
Purity:99.8%
Color and Shape:Soild
Molecular weight:487.36
Ref: TM-T23318L
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Albiglutide Fragment
CAS:
- 782500-75-8
Albiglutide fragment is a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).
Formula:C₁₄₈H₂₂₄N₄₀O₄₅
Purity:98%
Color and Shape:Solid
Molecular weight:3283.6
Ref: TM-TQ0004
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(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin
CAS:
- 73168-24-8
V1A receptor antagonist; blocks vasopressin & oxytocin, lowers Ca²⁺ levels (IC50: 5/30 nM); long-acting antivasopressor; anxiolytic in dorsal hippocampus.
Formula:C₅₂H₇₄N₁₄O₁₂S₂
Purity:98%
Color and Shape:White Lyophilized Powder
Molecular weight:1151.38
Ref: TM-TP2136
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Ro 25-1553
CAS:
- 159427-08-4
Ro 25-1553 is a 31-amino acid analog of vasoactive intestinal peptide (VIP) that functions as an agonist for the VIP2 receptor (VPAC2 receptor). In guinea pig models, Ro 25-1553 exhibits bronchodilator effects on tracheal smooth muscle contraction induced by neural stimuli or Carbachol.
Formula:C₁₆₀H₂₅₈N₄₆O₄₆
Color and Shape:Solid
Molecular weight:3562.04
Ref: TM-T203230
+ Info
A6770
CAS:
- 1331754-16-5
A6770 inhibits S1P lyase, causing [3H]dhS1P build-up in IT-79MTNC3 cells (EC50 <0.01 μM); less effective with vitamin B6 (EC50 <100 μM).
Formula:C₆H₈N₂O₂
Color and Shape:Solid
Molecular weight:140.142
Ref: TM-T36833
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ALEPH hydrochloride
CAS:
- 61638-08-2
ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.
Formula:C₁₂H₂₀ClNO₂S
Color and Shape:Solid
Molecular weight:277.81
Ref: TM-T203157
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L-770644 dihydrochloride
CAS:
- 182251-68-9
L-770644 dihydrochloride is a potent and selective agonist of the human beta3 adrenergic receptor.
Formula:C₃₀H₃₈ClN₇O₄S
Color and Shape:Solid
Molecular weight:628.19
Ref: TM-T24377L
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Clotizolam
CAS:
- 54123-06-7
Clotizolam is a thienotriazolodiazepine derivative with PAF antagonistic properties, exhibiting sedative, anxiolytic, anticonvulsant, and muscle relaxant effects.
Formula:C₁₅H₁₀Cl₂N₄S
Color and Shape:Solid
Molecular weight:349.24
Ref: TM-T203541
+ Info
Secretin (28-54), human TFA
Secretin (28-54), human TFA is a 27-amino acid peptide that works on the human Secretin receptor.
Formula:C₁₃₂H₂₂₁N₄₄F₃O₄₂
Purity:98%
Color and Shape:Solid
Molecular weight:3153.48
Ref: TM-TP1135
+ Info
Oxaprotiline hydrochloride
CAS:
- 39022-39-4
Oxaprotiline hydrochloride is an antidepressant.
Formula:C₂₀H₂₄ClNO
Purity:98%
Color and Shape:Solid
Molecular weight:329.86
Ref: TM-T25906L
+ Info
Apelin-12 acetate
Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor.
Formula:C₆₆H₁₀₇N₂₁O₁₆S
Purity:98.82%
Color and Shape:Solid
Molecular weight:1482.75
Ref: TM-T39823L
+ Info
Neurokinin B acetate(86933-75-7 free base)
Neurokinin B acetate, a tachykinin, interacts with NK1R, NK2R, & NK3R receptors to exert biological effects.
Formula:C₅₇H₈₃N₁₃O₁₆S₂
Purity:98.53%
Color and Shape:Solid
Molecular weight:1270.48
Ref: TM-TP1363L
+ Info
Atrial Natriuretic Peptide (ANP) (1-28), rat
CAS:
- 88898-17-3
Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
Formula:C₁₂₈H₂₀₅N₄₅O₃₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:3062.41
Ref: TM-TP1221
+ Info
LRGILS-NH2
CAS:
- 245329-01-5
LRGILS-NH2, reverse sequence of SLIGRL-NH2, is a control peptide for PAR2, affecting gut transit.
Formula:C₂₉H₅₆N₁₀O₇
Purity:98%
Color and Shape:Solid
Molecular weight:656.82
Ref: TM-T22933
+ Info
APJ receptor agonist 10
CAS:
- 3037373-19-3
APJ receptor agonist 10 (Compound I choline salt) modulates the activity of the APJ receptor, making it useful for pulmonary hypertension research. Compared to its free form, this compound exhibits improved bioavailability.
Formula:C₂₆H₃₆N₇O₆S
Color and Shape:Solid
Molecular weight:574.67
Ref: TM-T203502
+ Info
CB2R/FAAH modulator-2
CAS:
- 2876918-68-0
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.
Formula:C₂₄H₃₃NO₂
Purity:99.15%
Color and Shape:Soild
Molecular weight:367.52
Ref: TM-T67745
+ Info
ABT 724 trihydrochloride
CAS:
- 587870-77-7
ABT-724 trihydrochloride: selective D4 agonist; EC50=12.4nM(human),14.3nM(rat),23.2nM(ferret); for erectile dysfunction research.
Formula:C₁₇H₂₂Cl₃N₅
Purity:99.91%
Color and Shape:Solid
Molecular weight:402.75
Ref: TM-T22019
+ Info
TLX agonist 2
TLX agonist 2 (compound 31) is a TLX agonist with an EC50 of 0.1 μM and a Kd of 0.16 μM. This compound enhances transcriptional activity by binding to TLX, thereby boosting the expression of TLX target genes. TLX agonist 2 is utilized in research on neurodegenerative diseases.
Color and Shape:Odour Solid
Ref: TM-T200680
+ Info
Avorelin
CAS:
- 140703-49-7
Avorelin, a luteinizing hormone releasing hormone (LH-RH) agonist, is used potentially for the treatment of prostate.
Formula:C₆₅H₈₅N₁₇O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1296.48
Ref: TM-T26692
+ Info
ADTN
CAS:
- 53463-78-8
ADTN is an agonist of the dopamine receptor.
Formula:C₁₀H₁₃NO₂
Purity:98%
Color and Shape:Solid
Molecular weight:179.22
Ref: TM-T23643
+ Info
Ono 3708
CAS:
- 102191-05-9
Ono-3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo.
Formula:C₂₃H₃₇NO₄
Purity:98%
Color and Shape:Solid
Molecular weight:391.54
Ref: TM-T28242
+ Info
NI-0701
NI-0701 is a humanized antibody targeting CCL5/RANTES.
Purity:95.4% (SDS-PAGE); 99.4% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.4% (SEC-HPLC)
Color and Shape:Liquid
Molecular weight:145.5kDa
Ref: TM-T77486
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Ecraprost
CAS:
- 136892-64-3
Ecraprost is used as a prodrug of prostaglandin E1.
Formula:C₂₈H₄₈O₆
Color and Shape:Solid
Molecular weight:480.68
Ref: TM-T25362
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Paynantheine
CAS:
- 4697-66-9
Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.
Formula:C₂₃H₂₈N₂O₄
Color and Shape:Solid
Molecular weight:396.48
Ref: TM-T203202
+ Info
LY83583
CAS:
- 91300-60-6
LY83583 is a soluble guanylate cyclase competitive inhibitor with IC50 of 2 µM.
Formula:C₁₅H₁₀N₂O₂
Purity:99.54% - 99.80%
Color and Shape:Solid
Molecular weight:250.25
Ref: TM-T21576
+ Info
Guanylate cyclase-IN-1
CAS:
- 1361569-23-4
Guanylate cyclase-IN-1 (Example 46) is a specific inhibitor of guanylate cyclase, employed in research related to cardiovascular diseases.
Formula:C₂₀H₁₇FN₈O
Color and Shape:Solid
Molecular weight:404.409
Ref: TM-T38770
+ Info
IRL-1038
CAS:
- 144602-02-8
ETB endothelin receptor antagonist
Formula:C₆₈H₉₂N₁₄O₁₅S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1409.67
Ref: TM-TP2262
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[Leu31,Pro34]-Neuropeptide Y(human,rat)
CAS:
- 132699-73-1
High affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.
Formula:C₁₈₉H₂₈₄N₅₄O₅₆S
Purity:98%
Color and Shape:Solid
Molecular weight:4241
Ref: TM-TP1985
+ Info
Adrogolide HCl
CAS:
- 166591-11-3
Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.
Formula:C₂₂H₂₆ClNO₄S
Color and Shape:Solid
Molecular weight:435.96
Ref: TM-T29674
+ Info
Hemopressin(rat)
CAS:
- 568588-77-2
Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.
Formula:C₅₃H₇₇N₁₃O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1088.27
Ref: TM-TP1901
+ Info
O-2172
CAS:
- 521062-92-0
O-2172 is a carbocyclic analogue serving as an inhibitor of dopamine transporter (DAT), exhibiting IC50 values of 47 nM for DAT and 7000 nM for the serotonin transporter (SERT).
Formula:C₁₄H₁₆Cl₂O₂
Color and Shape:Solid
Molecular weight:287.18
Ref: TM-T203629
+ Info
Edg-2 receptor inhibitor 1
CAS:
- 1195941-38-8
Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).
Formula:C₂₇H₂₇NO₅
Purity:99.47%
Color and Shape:Solid
Molecular weight:445.51
Ref: TM-T4521
+ Info
PSB-22269
PSB-22269 is identified as a GPR17 antagonist with a Ki value of 8.91 nM. It exhibits significant inhibitory effects in cAMP and G protein activation assays. Molecular docking studies indicate that the binding site of PSB-22269 includes positively charged arginine residues and a hydrophobic pocket. PSB-22269 promotes myelin regeneration strategies, offering potential for multiple sclerosis research.
Formula:C₂₆H₂₁NO₆
Color and Shape:Solid
Molecular weight:443.45
Ref: TM-T203177
+ Info
Lanerkitug
Lanerkitug is a humanized IgG1λ2 antibody that targets CCR8, with HumanIgG1lambda2, Isotype Control serving as its corresponding isotype control.
Color and Shape:Odour Liquid
Ref: TM-T9901A-352
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(S)-Azelastine hydrochloride
CAS:
- 153408-27-6
(S)-Azelastine HCl, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.
Formula:C₂₂H₂₅Cl₂N₃O
Purity:98%
Color and Shape:Solid
Molecular weight:418.36
Ref: TM-T21109
+ Info
11-deoxy Prostaglandin E2
CAS:
- 35536-53-9
11-deoxy PGE2 is a synthetic PGE2 analog, a potent bronchoconstrictor, 5-30x stronger than PGF2α on human respiratory muscles.
Formula:C₂₀H₃₂O₄
Color and Shape:Solid
Molecular weight:336.47
Ref: TM-T38342
+ Info
GS-2278
CAS:
- 2750508-72-4
GS-2278 is an antagonist of LPAR1 (lysophosphatidic acid receptor 1) with potential applications in the study of idiopathic pulmonary fibrosis (IPF).
Formula:C₂₂H₁₆F₅N₉O₃
Color and Shape:Solid
Molecular weight:549.41
Ref: TM-T203480
+ Info
Galanin (1-15) (porcine, rat)
CAS:
- 112747-70-3
N-terminal galanin fragment used to mediate central cardiovascular effects
Formula:C₇₂H₁₀₅N₁₉O₂₀
Purity:98%
Color and Shape:Solid
Molecular weight:1556.72
Ref: TM-TP2250
+ Info
PG-931
CAS:
- 667430-81-1
Selective MC4 agonist with IC50: 0.58 nM (MC4), 55 nM (MC3); revives heart/lung function in shocked rats.
Formula:C₅₉H₈₅N₁₅O₁₁
Purity:98%
Color and Shape:Solid
Molecular weight:1180.41
Ref: TM-TP1953
+ Info
Vapiprost
CAS:
- 85505-64-2
Vapiprost is an antagonist of the thromboxane receptor and a prostaglandin receptor.
Formula:C₃₀H₃₉NO₄
Purity:98%
Color and Shape:Solid
Molecular weight:477.64
Ref: TM-T24931
+ Info
Abediterol napadisylate
CAS:
- 1044516-17-7
Abediterol napadisylate is a novel long-acting β2-agonist in persistent asthma that is efficacy, safe, and tolerable.
Formula:C₆₀H₆₈F₄N₄O₁₄S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1209.32
Ref: TM-T24995
+ Info
MDL 19301
CAS:
- 89388-38-5
MDL 19301 is a nonsteroidal, anti-inflammatory agent.
Formula:C₁₅H₂₁NS₂
Purity:98%
Color and Shape:Solid
Molecular weight:279.46
Ref: TM-T11981
+ Info
Orexin A (human, rat, mouse)
CAS:
- 205640-90-0
Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.
Formula:C₁₅₂H₂₄₃N₄₇O₄₄S₄
Purity:98%
Color and Shape:Solid
Molecular weight:3561.1
Ref: TM-TP1301
+ Info
5-HT2A receptor agonist-5
CAS:
- 2957888-63-8
5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.
Formula:C₂₃H₂₉N₃O
Color and Shape:Solid
Molecular weight:363.5
Ref: TM-T203649
+ Info
Ivabradine-d3 hydrochloride
CAS:
- 1217809-61-4
Ivabradine HCl: novel If blocker, IC50 2.9 μM, slows heart rate; D3 version is deuterium labeled.
Formula:C₂₇H₃₇ClN₂O₅
Purity:98%
Color and Shape:Solid
Molecular weight:508.07
Ref: TM-T11692
+ Info
Denrakibart
Denrakibart is a humanized IgG2κ antibody targeting CCL17, with HumanIgG2kappa, Isotype Control serving as the corresponding isotype control.
Color and Shape:Odour Liquid
Ref: TM-T9901A-444
+ Info
CGRP 8-37 (rat)
CAS:
- 129121-73-9
CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.
Formula:C₁₃₈H₂₂₄N₄₂O₄₁
Purity:99.28%
Color and Shape:Solid
Molecular weight:3127.51
Ref: TM-TP1323