GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,024 products)
- Adenosine Receptor(249 products)
- Adrenergic Receptor(3,029 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(159 products)
- CaSR(34 products)
- Cannabinoid Receptor(217 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(443 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(83 products)
- GPCR19(33 products)
- GRK(33 products)
- GTPase(22 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(42 products)
- Opioid Receptor(326 products)
- PAFR(14 products)
- PKA(52 products)
- S1P Receptor(17 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 5972 products of "GPCR/G-Protein"
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MRS4833
CAS:MRS4833 (compound 15) is an orally active, potent, competitive antagonist of P2Y14R, exhibiting IC50 values of 5.92 nM for hP2Y14R and 4.8 nM for mP2Y14R. It reduces airway eosinophilia in protease-mediated asthma models and reverses chronic neuropathic pain in mouse CCI models.Formula:C30H24F3NO3Color and Shape:SolidMolecular weight:503.51Fosrolapitant
CAS:Fosrolapitant is an antagonist of the neurokinin 1 (NK1) receptor.Formula:C27H29F6N2O8PColor and Shape:SolidMolecular weight:654.49Sulfinalol hydrochloride
CAS:Sulfinalol hydrochloride is an orally active β-adrenoceptor (β-adrenoceptor) antagonist that exhibits direct vasodilatory activity. It is also classified as an antihypertensive agent.Formula:C20H28ClNO4SColor and Shape:SolidMolecular weight:413.96BMS-986104
CAS:BMS-986104 is an effective selective modulator of the S1P1 receptor. It demonstrates efficacy in the mouse EAE model, comparable to that of FTY720. Furthermore, BMS-986104 shows promising remyelination properties in three-dimensional brain cell cultures subjected to lysophosphatidylcholine (LPC)-induced demyelination.Formula:C22H35NOColor and Shape:SolidMolecular weight:329.52GLP-1 receptor agonist 15
CAS:GLP-1 receptor agonist 15 (Example 4) is a GLP receptor agonist with an EC50 of 0.74 nM. It exhibits an IC50 of 10.1 μM against the hERG potassium ion channel. This compound is applicable for research in the diabetes field.Formula:C32H31ClFN3O5Color and Shape:SolidMolecular weight:592.057SAR-150640
CAS:SAR-150640, a selective β3-adrenergic receptor agonist, prevents an increase in MMP activity and production observed after LPS stimulation or in cases of chorioamnionitis.Formula:C25H35ClN2O7SColor and Shape:SolidMolecular weight:543.071'-Naphthoyl-2-methylindole
CAS:1'-Naphthoyl-2-methylindole (Compound 88) acts as a cannabinoid mimic and an inhibitor of Win 55212-2, displaying a 34% inhibition of [3H]Win 55212-2 binding to cannabinoid receptors at a concentration of 3 μM.Formula:C20H15NOColor and Shape:SolidMolecular weight:285.34LY 292728
CAS:LY 292728 is a highly potent antagonist of leukotriene B4 receptor.Formula:C34H29FO9Purity:98%Color and Shape:SolidMolecular weight:600.59LPA2 antagonist 5
CAS:LPA2 antagonist 5 (EX1) functions as an antagonist of LPA2, with an IC50 value of 4.05 nM.Formula:C17H17F3N2O5Color and Shape:SolidMolecular weight:386.323Netupitant metabolite Monohydroxy Netupitant
CAS:Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.Formula:C30H32F6N4O2Purity:98%Color and Shape:SolidMolecular weight:594.59Mesulergine hydrochloride
CAS:5-HT2A and 2C receptor antagonistFormula:C18H27ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:398.95RXFP1 receptor agonist-10
CAS:RXFP1 receptor agonist-10 (Compound 188) is an RXFP1 receptor agonist with an EC50 of 0.5 nM. It is useful for research into heart failure.Formula:C39H44F6N4O5Color and Shape:SolidMolecular weight:762.78LAB687
CAS:LAB687 (Compound 2a) is an inhibitor of microsomal triglyceride transfer protein (MTP) with an IC50 of 0.9 nM for inhibiting the secretion of apolipoprotein B (apoB) in HepG2 cells. Additionally, LAB687 acts as a Smoothened (Smo) antagonist, exhibiting IC50 values of 2.48 μM and 3.42 μM for mouse and human Smo receptors, respectively. This compound is effective in reducing triglyceride and low-density lipoprotein cholesterol (LDL-C) levels and in inhibiting the Hedgehog signaling pathway.Formula:C26H23F3N2O3Color and Shape:SolidMolecular weight:468.47GLP-1R agonist 33
CAS:GLP-1R agonist 33 (Compound 224) is a GLP-1 receptor agonist with potential applications in research related to diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).Formula:C30H27FN6O4Color and Shape:SolidMolecular weight:554.57Metrazoline
CAS:<p>Metrazoline (o-Methyl-tracizoline) acts as a ligand for adrenergic receptors (low affinity) and imidazoline I2 receptors.</p>Formula:C14H16N2O4Color and Shape:SolidMolecular weight:276.288TAK-661
CAS:TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.Formula:C13H21N5O3SColor and Shape:SolidMolecular weight:327.40COX-2-IN-6
CAS:COX-2-IN-6: Potent, selective COX-2 inhibitor; oral; IC50 0.84μM, Ki 69nM; blocks PGE2 synthesis; prevents colorectal cancer.Formula:C20H27NO6SPurity:99.29% - 99.32%Color and Shape:SoildMolecular weight:409.5KMN-80
CAS:KMN-80 is a potent, selective EP4 agonist with IC50 3 nM, spurring osteoblast differentiation, and showing in vivo bone repair efficacy.Formula:C21H33NO4Color and Shape:SolidMolecular weight:363.49SCH-900822
CAS:SCH-900822 is a potent and selective glucagon receptor antagonist.Formula:C34H43Cl2N7O2Color and Shape:SolidMolecular weight:652.66FK-3657
CAS:FK-3657 is a non-peptide antagonist of bradykinin (BK)-B2 receptor.Formula:C30H27Cl2N5O4Color and Shape:SolidMolecular weight:592.47EP4 receptor agonist 3
CAS:<p>EP4 receptor agonist 3 is an activator of the EP4 receptor and is useful for research in the DSS-induced colitis mouse model.</p>Formula:C21H27F2NO4Color and Shape:SolidMolecular weight:395.44SST1 receptor antagonist-1
CAS:SST1 receptor antagonist-1 (Compound 23) is a selective antagonist of the somatostatin receptor 1 (SST1), showing a pKd of 9.11 for rSST1 and 8.79 for hSST1. This compound is applicable in research related to retinal and endocrine dysfunction, cancer, and neuropsychiatric disorders.Formula:C29H31F2N3O2Color and Shape:SolidMolecular weight:491.57DMPX
CAS:DMPX (3,7-Dimethyl-1-propargylxanthine) is a caffeine-like compound capable of crossing the blood-brain barrier. It serves as an A2-selective adenosine receptor (AR) antagonist, effectively and selectively blocking the hypothermia and behavioral inhibition induced by A2 adenosine receptor agonists, such as NECA. DMPX is utilized in research on diseases like Parkinson's disease.Formula:C10H10N4O2Color and Shape:SolidMolecular weight:218.212YM-49598 iodide
CAS:YM-49598 iodide is a tachykinin NK-1 receptor antagonist. It inhibits drug-induced bladder contractions in rats with an IC50 of 11 μg/kg.Formula:C36H45Cl2IN2O2Color and Shape:SolidMolecular weight:735.57Nedocromil sodium
CAS:Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.Formula:C19H17NNaO7Purity:98%Color and Shape:SolidMolecular weight:394.335MK-8825
CAS:MK-8825 is a CGRP receptor antagonist.Formula:C31H30F2N6O3Color and Shape:SolidMolecular weight:572.61MRS2905 trisodium
CAS:MRS2905 (α,β-Methylene-2-thio-UDP) trisodium is a selective P2Y14R agonist with an EC50 of 0.92 nM. It shows no activity on UDP-activated P2Y6 receptors or other P2Y receptors.Formula:C10H13N2Na3O10P2SColor and Shape:SolidMolecular weight:484.199KF26777
CAS:KF26777 is a potent and selective antagonist of adenosine A3 receptor.Formula:C16H16BrN5OPurity:98%Color and Shape:SolidMolecular weight:374.23TAK-075
CAS:TAK-075 is an orally active CaSR antagonist with an IC50 value of 0.94 nM. It transiently stimulates parathyroid hormone (PTH) secretion in rats and effectively prevents significant reduction in PTH secretion due to the accumulation of active metabolites, thereby maintaining a normal secretion pattern. TAK-075 is applicable in research related to metabolic diseases and osteoporosis.Formula:C36H46N4O4SColor and Shape:SolidMolecular weight:630.84CGRP antagonist 7
CAS:CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.Formula:C30H32FN5O3Color and Shape:SolidMolecular weight:529.61Becondogrel
CAS:Becondogrel (2-Oxoclopidogrel) is a metabolite of Clopidogrel. It irreversibly inhibits the P2Y12 receptor, thereby preventing platelet aggregation and thrombosis.Formula:C16H16ClNO3SColor and Shape:SolidMolecular weight:337.821MRGPRX2 modulator-3
CAS:MRGPRX2 modulator-3 (Compound 4-400) is a quinoline derivative and an MRGPRX2 regulator. It is utilized in the investigation of MRGPRX2-related conditions, including allergies, itching, pain, inflammation, and autoimmune diseases.Formula:C21H21ClF3N5OColor and Shape:SolidMolecular weight:451.87Sitamaquine hydrochloride
CAS:Sitamaquine hydrochloride (WR 6026) is an orally active 8-aminoquinoline analog with antileishmanial activity. This compound inhibits mitochondrial complex II (succinate dehydrogenase) and is characterized by its lipophilic weak base properties. It rapidly accumulates in the acidic compartments of Leishmania parasites, predominantly localizing within the acidocalcisomes.Formula:C21H35Cl2N3OColor and Shape:SolidMolecular weight:416.43Revexepride
CAS:Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.Formula:C21H32ClN3O4Purity:98%Color and Shape:SolidMolecular weight:425.95Ici D1542
CAS:Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.Formula:C25H30N2O7Purity:98%Color and Shape:SolidMolecular weight:470.51ASP-2205
CAS:ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.Formula:C19H28N2OColor and Shape:SolidMolecular weight:300.44KARI 201 hydrochloride
CAS:KARI 201 hydrochloride is a selective, brain-penetrant, competitive inhibitor of acid sphingomyelinase (ASM) with an IC50 of 338.3 nM. It also acts as an agonist for the growth hormone-releasing peptide receptor (ghrelin receptor). Additionally, KARI 201 hydrochloride can enhance the neuropathological features of Alzheimer's disease.Formula:C14H29ClN4O2Color and Shape:SolidMolecular weight:320.86BMS-986120
CAS:BMS-986120: Oral, reversible PAR4 antagonist. IC50: 9.5 nM (human), 2.1 nM (monkey). Potent, selective antiplatelet.Formula:C23H23N5O5S2Color and Shape:SolidMolecular weight:513.59GLP-1R agonist 8
CAS:GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).Formula:C33H32N4O5Color and Shape:SolidMolecular weight:564.63Danavorexton
CAS:Danavorexton is an orexin receptor agonist.Formula:C21H32N2O5SColor and Shape:SolidMolecular weight:424.55SSR-241586
CAS:SSR-241586: Neurokinin antagonist, treats depression, schizophrenia, urinary issues, emesis, IBS.Formula:C32H42Cl2N4O3Purity:98%Color and Shape:SolidMolecular weight:601.61MRT-92
CAS:MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.Formula:C33H34N4O5Color and Shape:SolidMolecular weight:566.65LRH-1 modulator-1
CAS:LRH-1 modulator-1: potent agonist, boosts IL-10, reduces IL-1b/TNFa, anti-inflammatory in gut.Formula:C28H36N2O2SColor and Shape:SolidMolecular weight:464.66LP 12 hydrochloride hydrate
LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.Formula:C32H39N3O·HCl·xH2OColor and Shape:SolidHenagliflozin
CAS:Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.Formula:C22H24ClFO7Color and Shape:SolidMolecular weight:454.87CCR7 Ligand 1
CAS:CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.Formula:C22H29N5O5SColor and Shape:SolidMolecular weight:475.56Monlunabant
CAS:Monlunabant ((S)-MRI-1891), a solid dispersion compound, functions as an inhibitor of the cannabinoid CB1 receptor [1].Formula:C26H22ClF3N6O3SPurity:98%Color and Shape:SolidMolecular weight:591.00OP-2507
CAS:OP-2507, a prostacyclin agonist, is used potentially for the treatment of hepatic insufficiency and hypertension.Formula:C25H41NO4Purity:98%Color and Shape:SolidMolecular weight:419.6(Rac)-BI 703704
CAS:(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC).Formula:C32H37N3O4SPurity:98%Color and Shape:SolidMolecular weight:559.72CVT-5440
CAS:CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.Formula:C27H28N6O5Color and Shape:SolidMolecular weight:516.55Fasitibant
CAS:Fasitibant is a potent and selective nonpeptide kinin B2 receptor antagonist.Formula:C36H49Cl2N6O6SColor and Shape:SolidMolecular weight:764.78TAK-637
CAS:TAK-637 is a tachykinin 1 (NK1) receptor antagonist.Formula:C30H25F6N3O2Purity:98%Color and Shape:SolidMolecular weight:573.5316(R)-Iloprost
CAS:Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).Formula:C22H32O4Color and Shape:SolidMolecular weight:360.49GLP-1 receptor agonist 10
CAS:GLP-1 Receptor Agonist 10 (Compound 42), an agonist of the GLP receptor, reduces glucose excursions and inhibits food intake in mice. It is useful for research into type 2 diabetes (T2DM) and obesity [1].Formula:C30H28F4N6O5Molecular weight:628.57Cannabigerovarin
CAS:Cannabigerovarin (CBGV) is a compound categorized as a phytocannabinoid.Formula:C19H28O2Molecular weight:288.42GLP-1 receptor agonist 12
CAS:Compound 20A, known as GLP-1 receptor agonist 12, acts as an agonist of the GLP receptor. It is utilized in researching diseases like diabetes [1].Formula:C31H31FN6O4Molecular weight:570.61PF-00446687
CAS:PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).Formula:C28H36F2N2O2Purity:98%Color and Shape:SolidMolecular weight:470.595-HT2A receptor agonist-8
CAS:5-HT2A receptor agonist-8 (compound 8) is a potent 5-HT2A receptor agonist with an EC50 of 0.6784 nM. It is suitable for research related to depression and bipolar disorder.Formula:C22H27N3OMolecular weight:349.47CTW0404
CAS:CTW0404 is an effective positive allosteric modulator (PAM) of the 5-HT receptor, with promising implications for research into neuropsychiatric disorders.Formula:C21H33N3O2Molecular weight:359.51SPL-IN-1
CAS:SPL-IN-1 (compound C17) acts as a dual species inhibitor of sphingosine-1-phosphate lyase [1].Formula:C31H42N2O6S2Molecular weight:602.8PSB-KK1415
CAS:PSB-KK1415 is a selective agonist for the human orphan G protein-coupled receptor GPR18, with an EC50 of 19.1 nM.Formula:C24H23ClN6O2Molecular weight:462.93Elzasonan hydrochloride
CAS:Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.Formula:C22H24Cl3N3OSColor and Shape:SolidMolecular weight:484.87SLF1081851 hydrochloride
CAS:SLF1081851 (hydrochloride), a Spns2 inhibitor, effectively inhibits S1P release with an IC50 value of 1.93 μM. This compound is instrumental in the development and functioning of the immune system [1].Formula:C21H34ClN3OMolecular weight:379.97Tixanox sodium
CAS:Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.Formula:C15H9NaO5SColor and Shape:SolidMolecular weight:324.28Dinoxyline
CAS:Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27CP-481715
CAS:CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.Formula:C26H31FN4O4Color and Shape:SolidMolecular weight:482.55CI-988
CAS:CCK2 (CCK-B) receptor antagonistFormula:C35H42N4O6Purity:98%Color and Shape:SolidMolecular weight:614.73N-methyl Leukotriene C4
CAS:N-methyl LTC4 is a stable synthetic analog of LTC4 and a selective CysLT2 agonist, useful in studying leukotriene pharmacology.Formula:C31H49N3O9SColor and Shape:SolidMolecular weight:639.8Serotonin maleate
CAS:Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.Formula:C14H16N2O5Color and Shape:SolidMolecular weight:292.287Carazolol hydrochloride
CAS:Carazolol (BM 51052) hydrochloride is a potent antagonist of β1/β2-adrenoceptors and also serves as a powerful and selective agonist of β3-adrenoceptors. It is utilized in research focusing on hypertension.Formula:C18H23ClN2O2Molecular weight:334.84Org 274179-0
CAS:<p>Org 274179-0 is an effective allosteric antagonist of the thyroid-stimulating hormone (TSH) receptor, with an IC50 in the nanomolar range. It fully inhibits TSH (and TSI)-mediated activation of the TSH receptor with minimal impact on the efficacy of TSH. This compound can be utilized in studies of Graves' disease (GD).</p>Formula:C28H27F3N2O2Color and Shape:SolidMolecular weight:480.521Arpromidine
CAS:Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.Formula:C21H25FN6Color and Shape:SolidMolecular weight:380.462CRHR1 antagonist 1
CAS:CRHR1 antagonist 1 (compound 10a) is a non-peptide antagonist of corticotropin-releasing hormone receptor 1 (CRHR1). It serves as a useful tool in the study of psychiatric disorders.Formula:C24H34N4OColor and Shape:SolidMolecular weight:394.553AH22921
CAS:AH22921 is an EP4 prostaglandin receptor antagonist with the ability to antagonize the activation of adenylyl cyclase by prostaglandins in CHO cells. It induces a rightward shift in the PGE? concentration-response curve in these cells, functioning as a non-competitive antagonist. AH22921 is selective for the EP4 receptor, inhibiting its activity in CHO cells without affecting the PGE? concentration-response curve in NPE cells that contain the EP2 receptor.Formula:C29H35NO5Color and Shape:SolidMolecular weight:477.59Avitriptan
CAS:Avitriptan is a 5-HT1B/1D receptor agonist with pKi values of 7.44 for 5-HT1Brat, 7.68 for 5-HT1Bhuman, and 8.36 for 5-HT1Dhuman. It can induce contraction in isolated coronary arteries and is used for the treatment of migraines.Formula:C22H30N6O3SMolecular weight:458.577Hoe 892
CAS:Hoe 892 is a stable thia-thimo-analogue of prostacyclin and acts as a platelet aggregation inhibitor.Formula:C20H33NO4SColor and Shape:SolidMolecular weight:383.55BER-5
CAS:BER-5 is a potent MrgX2 antagonist, demonstrating broad-spectrum antagonistic activity against various MrgX2 agonists. It can inhibit Substance P(SP)-induced degranulation in LAD2 cells and alleviate SP-induced allergic reactions in mice. BER-5 is useful for researching mechanisms related to allergic reactions.Formula:C20H16O4Color and Shape:SolidMolecular weight:320.34(S)-Praziquantel
CAS:(S)-Praziquantel is the inactive isomer of R-praziquantel.Formula:C19H24N2O2Color and Shape:SolidMolecular weight:312.406NPRA agonist-11
CAS:NPRA agonist-11 (Example 161) is an NPRA (NPR1) agonist with AC50 values of 1.681 μM and 0.989 μM for human and monkey, respectively. It is applicable in research on cardiovascular and other diseases.Formula:C37H52FN7O2Color and Shape:SolidMolecular weight:645.85Nedemelteon
CAS:Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).Formula:C15H18N2O2Color and Shape:SolidMolecular weight:258.32LB-102
CAS:LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.Formula:C18H29N3O4SColor and Shape:SolidMolecular weight:383.51L 156903
CAS:L 156903 is a bioactive chemical. It also inhibits the binding of neurotensin to brain tissue.Formula:C35H41N7O5SColor and Shape:SolidMolecular weight:671.81Nifeviroc
CAS:Nifeviroc (TD-0232) is an orally active CCR5 antagonist, useful in HIV-1 infection research.Formula:C33H42N4O6Purity:98.14%Color and Shape:SolidMolecular weight:590.71CP-865569
CAS:CP-865569 is a CCR1 antagonist useful in the research of inflammatory and autoimmune diseases, including conditions such as rheumatoid arthritis and multiple sclerosis.Formula:C22H26ClFN2O5SColor and Shape:SolidMolecular weight:484.969Sulprostone
CAS:EP3 and EP1 receptor agonistFormula:C23H31NO7SPurity:98%Color and Shape:White To Off-White SolidMolecular weight:465.56GHSR-1a agonist-1
CAS:GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a) with an EC50 of 0.49 nM. It effectively stimulates the release of endogenous growth hormone by activating GHSR-1a. Doses as low as 0.1 mg/kg (administered orally) can increase body weight and length in 4-week-old rats. GHSR-1a agonist-1 is applicable in research on pediatric growth and developmental delays.Formula:C30H37N5O4Color and Shape:SolidMolecular weight:531.646RG-15
CAS:RG-15 is an orally active dopamine receptor antagonist with high affinity for the human D2 receptor (pKi of 8.23) and human D3 receptor (pKi of 10.49). It inhibits dopamine-stimulated [35S]GTPγS binding with IC50 values of 21.2 nM in rat striatal membranes, 36.7 nM in mouse A9 cells expressing human D2L receptors, and 7.2 nM in CHO cells expressing human D3 receptors. RG-15 enhances dopamine turnover and synthesis in the striatum and olfactory bulb of mice, exhibiting antipsychotic activity.Formula:C25H32Cl2F3N5O2SColor and Shape:SolidMolecular weight:594.52CCR5 antagonist 1
CAS:CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.Formula:C39H46ClF2N5O3SPurity:98%Color and Shape:SolidMolecular weight:738.33BI 639667
CAS:BI 639667, an azaindazole-class compound, potently inhibits CCR1 (IC50=1.8 nM in calcium flux assays).Formula:C22H18FN5O3SPurity:99.86%Color and Shape:SolidMolecular weight:451.47Toladryl
CAS:Toladryl is a derivative of Diphenhydramine that can cross the blood-brain barrier and exhibits oral activity, with antihistamine and anticholinergic properties. Its anticholinergic effects are approximately a tenth of those seen with Diphenhydramine, yet it offers 2-4 times the protection against lethal doses of histamine in guinea pigs. The side effects of Toladryl are fewer and milder compared to Diphenhydramine; however, at higher doses, it may cause symptoms such as insomnia, agitation, and disorientation related to the central nervous system. Toladryl is utilized in the research of allergic diseases.Formula:C18H23NOColor and Shape:SolidMolecular weight:269.38VU0514009
CAS:VU0514009 is a competitive antagonist of chemokine-like receptor 1 (CMKLR1) with an EC50 of 2 nM. It effectively inhibits chemerin-9-induced arrestin recruitment and receptor internalization, significantly reducing Ca2+ flux responses in HEK293 cells. This compound shows potential for research in inflammatory diseases and metabolic syndrome.Formula:C21H20ClN3O5S2Color and Shape:SolidMolecular weight:493.9816(S)-Iloprost
CAS:Iloprost, a potent prostacyclin analog, binds to human IP & EP1 receptors with high affinity; inhibits platelet aggregation effectively.Formula:C22H32O4Color and Shape:SolidMolecular weight:360.49S1P1 agonist 5
Selective oral S1P1 agonist 5 inhibits lymphocyte drainage, potential for MS research.Formula:C23H24ClN2NaO4Color and Shape:SolidMolecular weight:450.89AChE/BChE-IN-21
CAS:AChE/BChE-IN-21 is an antagonist of the histamine H3 receptor, a calcium channel blocker, and an acetylcholinesterase inhibitor. It exhibits neuroprotective activities against H2O2 and Aβ1-40, and can restore cognitive functions in AD mice.Formula:C38H54N4O4Color and Shape:SolidMolecular weight:630.86BI 703704
CAS:BI 703704, a soluble guanylate cyclase (sGC) activator, inhibits the progression of diabetic nephropathy in the ZSF1 rat [1].Formula:C32H37N3O4SPurity:98%Color and Shape:SolidMolecular weight:559.729-Methyl-β-carboline
CAS:9-Methyl-β-carboline is a cognitive enhancer with neuroprotective, neurorestorative, and anti-inflammatory properties. Its behavioral effects may be linked to hippocampal dopamine levels and the stimulation of dendritic and synaptic proliferation.Formula:C12H10N2Color and Shape:SolidMolecular weight:182.221BAY 38-7271
CAS:BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).Formula:C20H21F3O5SPurity:98%Color and Shape:SolidMolecular weight:430.44D1R antagonist 1
CAS:Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].Formula:C22H26BrNO4Purity:98%Color and Shape:SolidMolecular weight:448.35ONO-8809
CAS:ONO-8809: Thromboxane A2 antagonist, reduces airway hyperresponse, macrophage accumulation, and MMP-9 in SHRSP brains.Formula:C30H46BrNO4SPurity:98%Color and Shape:SolidMolecular weight:596.66ZD6021
CAS:ZD6021 is an antagonist of neurokinin 1 receptor.Formula:C35H35Cl2N3O2SPurity:98%Color and Shape:SolidMolecular weight:632.64Delmadinone acetate
CAS:Delmadinone acetate is an orally active compound used to control estrus and ovulation in both female and male pets. It induces adrenal suppression by inhibiting the pituitary release of ACTH.Formula:C23H27ClO4Color and Shape:SolidMolecular weight:402.911MDA77
CAS:MDA77 is a CB2 agonist with an EC50 value of 5.82 nM and exhibits no activity towards CB1.Formula:C21H23N3O3Color and Shape:SolidMolecular weight:365.43K-14585
CAS:K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.Formula:C51H56Cl2N8O4Color and Shape:SolidMolecular weight:915.95BI-44370
CAS:BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.Formula:C35H47N5O6Color and Shape:SolidMolecular weight:633.78AM11638
CAS:AM11638 is an endogenous cannabinoid analogue that targets cannabinoid receptors (CB1 and CB2 receptors), exhibiting analgesic properties. It shows potential for research in neurological disorders and inflammation-related diseases.Formula:C27H41NO2Color and Shape:SolidMolecular weight:411.62Vofopitant
CAS:Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).Formula:C21H23F3N6OPurity:97.86%Color and Shape:SolidMolecular weight:432.44AZD5462
CAS:AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.Formula:C30H41FN2O6Purity:98.32% - 99.63%Color and Shape:SolidMolecular weight:544.65Vofopitant dihydrochloride
CAS:Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.Formula:C21H25Cl2F3N6OPurity:98.99%Color and Shape:SolidMolecular weight:505.36Ref: TM-T13329L
1mg99.00€5mg235.00€10mg376.00€25mg712.00€50mg1,064.00€100mg1,454.00€500mg2,822.00€1mL*10mM (DMSO)261.00€LSN3318839
CAS:<p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>Formula:C26H23Cl2N3O2Purity:99.21%Color and Shape:SolidMolecular weight:480.39AZD-5672
CAS:AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.Formula:C32H38F2N2O5S2Purity:98.1%Color and Shape:SolidMolecular weight:632.78Ref: TM-T30260
1mg202.00€5mg459.00€10mg643.00€25mg938.00€50mg1,311.00€100mg1,786.00€1mL*10mM (DMSO)560.00€SB-224289 hydrochloride
CAS:SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formula:C32H33ClN4O3Purity:98.99% - 99.96%Color and Shape:SolidMolecular weight:557.08SB-423562
CAS:SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.Formula:C26H32N2O4Purity:99.22%Color and Shape:SolidMolecular weight:436.54Ref: TM-T12846
1mg39.00€5mg85.00€10mg126.00€25mg221.00€50mg338.00€100mg467.00€200mg640.00€1mL*10mM (DMSO)94.00€BQ-788
CAS:BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formula:C34H51N5O7Purity:98.81%Color and Shape:SolidMolecular weight:641.8Ref: TM-T10595
1mg137.00€2mg188.00€5mg329.00€10mg472.00€25mg753.00€50mg1,017.00€100mg1,378.00€500mg2,737.00€1mL*10mM (DMSO)360.00€Treprostinil diethanolamine
CAS:<p>Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,</p>Formula:C27H45NO7Purity:99.86%Color and Shape:SolidMolecular weight:495.65BMS-986141
CAS:BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Formula:C27H23N5O5S2Purity:98.43% - 99.26%Color and Shape:SolidMolecular weight:561.63Dersimelagon
CAS:Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.Formula:C36H45F4N3O5Purity:97.35% - 98.23%Color and Shape:SolidMolecular weight:675.75PF-07258669
CAS:PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.Formula:C25H27FN6O2Purity:99.9%Color and Shape:SolidMolecular weight:462.52Rolapitant hydrochloride
CAS:Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.Formula:C25H27ClF6N2O2Purity:98.35% - 99.79%Color and Shape:SolidMolecular weight:536.94Ref: TM-T3724
1mg153.00€5mg365.00€10mg520.00€25mg780.00€50mg1,054.00€100mg1,425.00€200mg1,882.00€1mL*10mM (DMSO)439.00€CYM 9484
CAS:CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.Formula:C27H31N3O3S2Color and Shape:SolidMolecular weight:509.68SR 146131
CAS:SR 146131 is a potent and selective agonist of the nonpeptide receptor.Formula:C32H36ClN3O5SPurity:98%Color and Shape:SolidMolecular weight:610.16BIBP3226 TFA
CAS:BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).Formula:C29H32F3N5O5Color and Shape:SolidMolecular weight:587.59Protease-Activated Receptor-4
CAS:Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.Formula:C33H46N8O7Purity:98%Color and Shape:SolidMolecular weight:666.77HOKU-81
CAS:HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.Formula:C12H18ClNO2Color and Shape:SolidMolecular weight:243.73JMV 2959
CAS:JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).Formula:C30H32N6O2Color and Shape:SolidMolecular weight:508.61SHA 68
CAS:SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR) with IC50 values of 22.0 nM for NPSR Asn107 and 23.8 nM for NPSR Ile107.Formula:C26H24FN3O3Purity:98%Color and Shape:SolidMolecular weight:445.49Pumosetrag Hydrochloride
CAS:Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formula:C15H18ClN3O2SPurity:98%Color and Shape:SolidMolecular weight:339.84SB-399885 hydrochloride
CAS:SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Formula:C18H22Cl3N3O4SPurity:98%Color and Shape:SolidMolecular weight:482.81ML-290
CAS:ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.Formula:C24H21F3N2O5SColor and Shape:SolidMolecular weight:506.49Beraprost sodium
CAS:Beraprost sodium is a stable and orally active prodrug of PGI2.Formula:C24H29NaO5Color and Shape:SolidMolecular weight:420.481Arotinolol
CAS:Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Formula:C15H21N3O2S3Color and Shape:White SolidMolecular weight:371.54ML-00253764 hydrochloride
CAS:ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).Formula:C18H19BrClFN2OColor and Shape:SolidMolecular weight:413.717-Desmethyl-agomelatine
CAS:7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.Formula:C14H15NO2Color and Shape:SolidMolecular weight:229.27Sarizotan
CAS:Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.Formula:C22H21FN2OColor and Shape:SolidMolecular weight:348.421Picumeterol
CAS:Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.Formula:C21H29Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:426.38Anti-GLP1R Antibody
<p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>Color and Shape:Odour Liquid3-Hydroxybenzylamine
CAS:3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.Formula:C7H9NOColor and Shape:SolidMolecular weight:123.155TAK-683
CAS:TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.Formula:C64H83N17O13Purity:98%Color and Shape:SolidMolecular weight:1298.456-Chloro-5-(2-chloroethyl)indolin-2-one
CAS:6-Chloro-5-(2-chloroethyl)indolin-2-one is a useful organic compound for research related to life sciences. The catalog number is T64862 and the CAS number is 118289-55-7.Formula:C10H9Cl2NOColor and Shape:SolidMolecular weight:230.09BRL 15572
CAS:BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.Formula:C25H27ClN2OColor and Shape:SolidMolecular weight:406.954-Hydroxyatomoxetine
CAS:4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.Formula:C17H21NO2Purity:98%Color and Shape:SolidMolecular weight:271.35(R)-(-)-α-Methylhistamine dihydrochloride
CAS:R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.Formula:C6H13Cl2N3Color and Shape:SolidMolecular weight:198.091-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol
CAS:1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol is a useful organic compound for research related to life sciences. The catalog number is T65156 and the CAS number is 24155-42-8.Formula:C11H10Cl2N2OColor and Shape:SolidMolecular weight:257.11dapitant
CAS:Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.Formula:C37H39NO4Color and Shape:SolidMolecular weight:561.71Amelubant
CAS:Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.Formula:C33H34N2O5Purity:98%Color and Shape:SolidMolecular weight:538.63Desmethyl cariprazine
CAS:Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).Formula:C20H30Cl2N4OPurity:98%Color and Shape:SolidMolecular weight:413.38TAK-448
CAS:TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.Formula:C58H80N16O14Purity:98%Color and Shape:SolidMolecular weight:1225.36Patecibart
CAS:<p>Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).</p>Purity:98%Color and Shape:LiquidVornorexant
CAS:Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.Formula:C23H22FN7O2Color and Shape:SolidMolecular weight:447.474Goserelin acetate(65807-02-5 Free base)
<p>Goserelin acetate （ICI-118630 acetate） is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.</p>Purity:99.77%Color and Shape:Odour SolidRef: TM-T36918L
Discontinued productSKF 89748
CAS:SKF 89748 is an agonists of alpha 1-adrenoceptor.Formula:C12H17NOSPurity:98%Color and Shape:SolidMolecular weight:223.334-Hydroxypropranolol hydrochloride
CAS:4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).Formula:C16H22ClNO3Purity:98%Color and Shape:SolidMolecular weight:311.8GSK-3050002
<p>GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.</p>Color and Shape:Odour LiquidCRTh2 antagonist 3
CAS:CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.Formula:C19H20N2O3SPurity:98%Color and Shape:SolidMolecular weight:356.44(Rac)-Zevaquenabant
CAS:(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.Formula:C25H21ClF3N5O2SColor and Shape:SolidMolecular weight:547.981-Oleoyl Lysophosphatidic Acid
CAS:<p>1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.</p>Formula:C21H41O7PColor and Shape:SolidMolecular weight:436.52Ref: TM-T36907
Discontinued productPropiram fumarate HCl
CAS:<p>Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.</p>Formula:C16H25N3O·xClHPurity:99.25%Color and Shape:SoildN-methyl-2-AI (hydrochloride)
CAS:N-methyl-2-AI (hydrochloride) is a useful organic compound for research related to life sciences. The catalog number is T66396 and the CAS number is 10408-85-2.Formula:C10H14ClNColor and Shape:SolidMolecular weight:183.68BX471 hydrochloride
CAS:BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.Formula:C21H25Cl2FN4O3Purity:98%Color and Shape:SolidMolecular weight:471.35Canagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Formula:C24H25FO5SPurity:98%Color and Shape:SolidMolecular weight:448.542-Methyl-5-HT hydrochloride
CAS:2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formula:C11H15ClN2OPurity:98%Color and Shape:SolidMolecular weight:226.7RU 24969 succinate
CAS:<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Formula:C18H22N2O5Color and Shape:SolidMolecular weight:346.38Pamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Formula:C23H16O6Purity:99.99%Color and Shape:Fine Yellow PowderMolecular weight:388.37Neurokinin antagonist 1
CAS:Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.Formula:C38H40N4O3Purity:>99.99%Color and Shape:SolidMolecular weight:600.75MEN11467
CAS:MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.Formula:C38H40N4O3Purity:>99.99%Color and Shape:SolidMolecular weight:600.75Imetit dihydrobromide
CAS:Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Formula:C6H12Br2N4SPurity:98%Color and Shape:SolidMolecular weight:332.06SB251023
CAS:SB251023 is an agonist of β3-adrenoceptor.Formula:C28H34NO6PColor and Shape:SolidMolecular weight:511.55GR 218,231
CAS:GR 218,231 is a selective antagonist of D3 dopamine receptor.Formula:C24H33NO3SPurity:98%Color and Shape:SolidMolecular weight:415.59Flumexadol
CAS:Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Formula:C11H12F3NOPurity:98%Color and Shape:SolidMolecular weight:231.21AEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Formula:C29H40O3Purity:99.58%Color and Shape:SolidMolecular weight:436.63S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Formula:C25H26F3NO3Purity:98%Color and Shape:SolidMolecular weight:445.472-MNG
CAS:<p>2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.</p>Formula:C8H8N2O3SColor and Shape:LiquidMolecular weight:212.23Dimethandrolone Undecanoate
CAS:Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.Formula:C31H50O3Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:470.73Ref: TM-T27176
Discontinued product
