GPCR/G-Protein

GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.

Subcategories of "GPCR/G-Protein"

Show 18 more subcategories

Found 5378 products of "GPCR/G-Protein"

Purity (%)

100

products per page.

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Octodrine
CAS:
- 543-82-8
Octodrine (2-Amino-6-methylheptane) is primarily used as a pharmaceutical intermediate for Octamylamine; it also functions as a local anesthetic and vasoconstrictor.
Formula:C₈H₁₉N
Purity:99.98%
Color and Shape:Clear Colorless To Light Yellow Liquid
Molecular weight:129.24
Ref: TM-T0043
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Israpafant
CAS:
- 117279-73-9
Israpafant: PAF receptor blocker, IC50 0.84nM, hinders platelet aggregation, eosinophil activation, boosts calcium transit, anti-nephrotoxic.
Formula:C₂₈H₂₉ClN₄S
Color and Shape:Solid
Molecular weight:489.07
Ref: TM-T27638
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(±)12-HEPE
CAS:
- 81187-21-5
(±)12-HEPE is produced by non-enzymatic oxidation of EPA.
Formula:C₂₀H₃₀O₃
Color and Shape:Solid
Molecular weight:318.457
Ref: TM-T35506
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Fasitibant chloride
CAS:
- 1157852-02-2
Fasitibant chloride, a potent B2R blocker, alleviates pain and swelling in arthritis.
Formula:C₃₆H₄₉Cl₃N₆O₆S
Color and Shape:Solid
Molecular weight:800.23
Ref: TM-T38544
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CB2R/FAAH modulator-3
CAS:
- 2876918-67-9
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.
Formula:C₂₂H₃₁NO₂
Purity:99.81%
Color and Shape:Soild
Molecular weight:341.49
Ref: TM-T67747
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AL12180
CAS:
- 748816-43-5
AL12180 is a bioactive chemical.
Formula:C₂₁H₂₇ClO₆
Color and Shape:Solid
Molecular weight:410.89
Ref: TM-T29810
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Substance P, Free Acid
CAS:
- 71977-09-8
Substance P, Free Acid is a synthetic analog of native Substance P, however, it lacks the biological activity exhibited by Substance P.
Formula:C₆₃H₉₇N₁₇O₁₄S
Purity:98%
Color and Shape:Solid
Molecular weight:1348.61
Ref: TM-TP1788
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MGV354
MGV354 is a soluble activator of guanylate cyclase(sGC) with EC 50 s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively [1] [2].
Formula:C₃₅H₃₇N₅O₃
Purity:98%
Color and Shape:Solid
Molecular weight:575.7
Ref: TM-T12888
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Eledoisin
CAS:
- 69-25-0
Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family
Formula:C₅₄H₈₅N₁₃O₁₅S
Purity:98%
Color and Shape:Solid
Molecular weight:1188.4
Ref: TM-TP1177
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Norisoboldine hydrochloride
CAS:
- 5083-84-1
Norisoboldine hydrochloride: an oral AhR agonist from Radix Linderae, for Rheumatoid arthritis and Ulcerative colitis research.
Formula:C₁₈H₂₀ClNO₄
Color and Shape:Solid
Molecular weight:349.81
Ref: TM-T75433
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Neurokinin A(4-10) TFA
Neurokinin A (4-10) TFA is a tachykinin NK 2 receptor agonist [1] .
Formula:C₃₆H₅₅F₃N₈O₁₂S
Color and Shape:Solid
Molecular weight:880.93
Ref: TM-T75742
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Calcitonin-13C6,15N4 TFA
Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.
Formula:C₁₄₀₁C₅H₂₄₀N₄₃₁₅NO₄₈S₂·5C₂HF₃O₂
Color and Shape:Solid
Molecular weight:4007.93
Ref: TM-T201476
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Secretoneurin, rat
CAS:
- 149146-12-3
Secretoneurin, rat, a 33-amino acid polypeptide, is generated by proteolytic processing of secretogranin II (SgII).
Formula:C₁₅₉H₂₅₂N₄₀O₅₈
Purity:98%
Color and Shape:Solid
Molecular weight:3651.95
Ref: TM-TP1597
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Oxyntomodulin
CAS:
- 62340-29-8
GLP-1 analog modulates appetite, boosts metabolism, and curbs gastric acid. Increases cAMP, mildly stimulates glucagon receptor.
Formula:C₁₉₂H₂₉₅N₅₉O₆₀S
Purity:98%
Color and Shape:Solid
Molecular weight:4421.86
Ref: TM-TP1976
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IRL-1620 acetate
IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.
Formula:C₈₈H₁₂₁N₁₇O₂₉
Purity:96.64%
Color and Shape:Solid
Molecular weight:1881
Ref: TM-T15595L
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SC 31391
CAS:
- 144730-93-8
SC 31391 is a PGE1 analog.
Formula:C₂₄H₃₂O₆
Color and Shape:Solid
Molecular weight:416.51
Ref: TM-T34550
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17-phenyl trinor Prostaglandin E2 ethyl amide
CAS:
- 1219032-20-8
17-phenyl trinor PGE2 ethyl amide, an EP1/EP3 agonist (Ki: 14-54 nM), enhances lipid solubility and tissue uptake, is a potent antifertility agent.
Formula:C₂₅H₃₅NO₄
Color and Shape:Solid
Molecular weight:413.55
Ref: TM-T37996
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γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.
Formula:C₁₁H₁₇F₃N₂O₇
Color and Shape:Solid
Molecular weight:346.26
Ref: TM-T201610
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(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin
CAS:
- 176714-12-8
(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1].
Formula:C₅₂H₇₆N₁₄O₁₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1137.38
Ref: TM-T80137
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ORG 2766
CAS:
- 50913-82-1
ORG 2766 is an ACTH 4-9 (H-Met(O)-Glu-His-Phe-D-Lys-Phe-OH) analog and neurotrophic peptide.
Formula:C₄₀H₅₅N₉O₁₁S
Color and Shape:Solid
Molecular weight:869.99
Ref: TM-T33820
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Mosliciguat
CAS:
- 2231749-54-3
Mosliciguat is a guanylate cyclase activator.
Formula:C₄₁H₃₆ClF₃N₂O₅
Color and Shape:Solid
Molecular weight:729.19
Ref: TM-T39723
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S1R agonist 1
CAS:
- 193354-70-0
Compound 6b: Selective S1R agonist, K i = 0.93 nM (S1R), 72 nM (S2R); neuroprotective against ROS, NMDA toxicity.
Formula:C₂₀H₂₅NO
Color and Shape:Solid
Molecular weight:295.42
Ref: TM-T74822
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Mibenratide TFA
Mibenratide TFA, a small cyclic peptide, functions as an adrenergic β1 receptor antagonist and has potential applications in heart failure research [1].
Purity:98%
Color and Shape:Odour Solid
Ref: TM-T81798
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Fenoldopam
CAS:
- 67227-56-9
Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).
Formula:C₁₆H₁₆ClNO₃
Purity:98%
Color and Shape:Solid
Molecular weight:305.76
Ref: TM-T22779
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Luseogliflozin
CAS:
- 898537-18-3
Luseogliflozin inhibits SGLT2 for glucose uptake with 1.10 nM potency.
Formula:C₂₃H₃₀O₆S
Color and Shape:Solid
Molecular weight:434.55
Ref: TM-T21399
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(Leu31,Pro34)-Peptide YY (human) (TFA)
"(Leu31,Pro34)-Peptide YY (human) (TFA) is the trifluoroacetic acid (TFA) form of (Leu31,Pro34)-Peptide YY (human), a derivative of Peptide YY that acts as a
Formula:C₁₉₅H₂₉₆N₅₄O₅₆·xC₂HF₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:4292.75 (free base)
Ref: TM-T80087
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BAY-6672
CAS:
- 2247517-53-7
BAY-6672 is, a selective,oral, highly potent human prostaglandin F (FP) receptor antagonist, exerts antifibrotic effects by inhibiting PGF₂α activity.
Formula:C₂₆H₂₇BrClN₃O₃
Purity:99.51%
Color and Shape:Solid
Molecular weight:544.87
Ref: TM-T39760
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BMY-14802
CAS:
- 105565-56-8
BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.
Formula:C₁₈H₂₂F₂N₄O
Purity:99.84%
Color and Shape:Soild
Molecular weight:348.39
Ref: TM-T67739
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(R)-(+)-Atenolol
CAS:
- 56715-13-0
(R)-(+)-Atenolol ((R)-Atenolol) is a cardioselective beta-1 adrenergic blocker, which properties are similar to propranolol, but without a negative inotropic effect.
Formula:C₁₄H₂₂N₂O₃
Purity:98.72%
Color and Shape:Solid
Molecular weight:266.34
Ref: TM-T0007L
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Benzomalvin A
CAS:
- 157047-96-6
Benzomalvin A is a filamentous fungal secondary metabolite.
Formula:C₂₄H₁₉N₃O₂
Color and Shape:Solid
Molecular weight:381.43
Ref: TM-T30407
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Spantide II
CAS:
- 129176-97-2
Spantide II is an antagonist of tachykinin.
Formula:C₈₆H₁₀₄Cl₂N₁₈O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1668.77
Ref: TM-TP2353
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Bertilimumab
CAS:
- 375348-49-5
Bertilimumab (CAT 213; iCo-008), a human monoclonal antibody that targets eotaxin-1 (CCL11), shows promise in the research of allergic disorders [1].
Color and Shape:Liquid
Ref: TM-T76928
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[D-Trp8]-γ-MSH
CAS:
- 321351-81-9
[D-Trp8]-γ-MSH is a selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively).
Formula:C₇₄H₉₉N₂₁O₁₆S
Purity:98%
Color and Shape:Solid
Molecular weight:1570.79
Ref: TM-TP1893
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Thrombin Receptor Activator for Peptide 5 (TRAP-5)
CAS:
- 141685-53-2
Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5), used in the research of coronary heart disease (CHD).
Formula:C₃₀H₅₀N₈O₇
Purity:98%
Color and Shape:Solid
Molecular weight:634.77
Ref: TM-T7496
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Dipentylone hydrochloride
CAS:
- 17763-13-2
Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.
Formula:C₁₄H₂₀ClNO₃
Purity:99.94%
Color and Shape:Solid
Molecular weight:285.77
Ref: TM-T205977
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M40
CAS:
- 143896-17-7
Potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat
Formula:C₉₄H₁₄₅N₂₃O₂₄
Purity:98%
Color and Shape:Solid
Molecular weight:1981.33
Ref: TM-TP1992
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FXR/TGR5 agonist 1
CAS:
- 2677689-72-2
FXR/TGR5 agonist 1 acts as an agonist on both FXR and TGR5 receptors and is utilized for treating fatty liver disease.
Formula:C₃₁H₃₂ClN₃O₃
Color and Shape:Solid
Molecular weight:530.07
Ref: TM-T40302
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HTL22562
CAS:
- 2097085-63-5
HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.
Formula:C₄₀H₄₉N₁₁O₅
Color and Shape:Solid
Molecular weight:763.904
Ref: TM-T39522
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RF9 acetate
RF9 acetate is an effective and selective antagonist of Neuropeptide FF receptor with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.
Formula:C₂₈H₄₂N₆O₅
Purity:99.77%
Color and Shape:Solid
Molecular weight:542.67
Ref: TM-T16738L
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Spns2-IN-1
Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immune
Purity:98%
Color and Shape:Odour Solid
Ref: TM-T81114
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Neuronostatin-13 (human)
CAS:
- 1096485-24-3
Neuronostatin-13: human-conserved, 13-amino-acid peptide with amidated C-terminus.
Formula:C₆₄H₁₁₀N₂₀O₁₆
Purity:98%
Color and Shape:Solid
Molecular weight:1415.68
Ref: TM-TP1827
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1-Octadecyl Lysophosphatidic Acid
CAS:
- 52977-29-4
1-Octadecyl LPA, an LPA analog with stearic acid at sn-1, has strong platelet aggregation (EC50=9 nM) via G protein receptors.
Formula:C₂₁H₄₅O₆P
Color and Shape:Solid
Molecular weight:424.559
Ref: TM-T36768
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JMV-1645
CAS:
- 284037-77-0
JMV-1645 is an effective and selective B(1) bradykinin receptor antagonist.
Formula:C₄₉H₆₉N₁₃O₁₂S
Purity:98%
Color and Shape:Solid
Molecular weight:1064.23
Ref: TM-T25555
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[Deamino-Pen1,Val4,D-Arg8]-vasopressin
CAS:
- 64158-84-5
[Deamino-Pen1,Val4,D-Arg8]-vasopressin (AVP-A) is an antagonist of arginine-vasopressin (AVP).
Formula:C₄₈H₆₉N₁₃O₁₁S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1068.27
Ref: TM-T83501
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Substance P (1-9)
CAS:
- 57468-17-4
Substance P (1-9), a nonapeptide, slows its own inactivation and stimulates neurons.
Formula:C₅₂H₇₇N₁₅O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:1104.26
Ref: TM-TP1819
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ACTH (34-39)
CAS:
- 69454-10-0
ACTH (34-39) is an adrenocorticotropic hormone fragment.
Formula:C₃₇H₅₀N₆O₉
Purity:98%
Color and Shape:Solid
Molecular weight:722.83
Ref: TM-TP1751
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AR ligand 40
AR ligand 40 (compound 19c) is an Adenosine A1 Receptor ligand with antagonistic activity. It exhibits antiproliferative effects on SW480, SW48, HCT116, K562, MDA-MB-231, and A549 cells, with EC50 values of 7, 10, 12, 13, 15, and 39 μM, respectively.
Formula:C₂₁H₂₅N₅
Color and Shape:Solid
Molecular weight:347.211
Ref: TM-T207383
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SAG dihydrochloride
CAS:
- 2702366-44-5
SAG dihydrochloride: potent Smo agonist, activates Hedgehog pathway, counters Cyclopamine. EC50=3 nM, Kd=59 nM.
Formula:C₂₈H₃₀Cl₃N₃OS
Purity:>99.99%
Color and Shape:Soild
Molecular weight:562.98
Ref: TM-T40465
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WAY-620645
CAS:
- 742116-45-6
WAY-620645 is a CCK antagonist with antitumor and analgesic activities.
Formula:C₂₂H₂₂N₄O₂
Purity:99.89%
Color and Shape:Solid
Molecular weight:374.44
Ref: TM-T9991
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Lysophosphatidic acid
CAS:
- 22002-87-5
Lysophosphatidic acid is a bioactive chemical.
Formula:C₂₁H₄₁O₇P
Color and Shape:Solid
Molecular weight:436.52
Ref: TM-T33076
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12-epi Leukotriene B4
CAS:
- 83709-73-3
LTB4 is made enzymatically (12(R)-specific) and non-enzymatically (6-trans-12-epi mix). 12-epi LTB4 has low receptor activity.
Formula:C₂₀H₃₂O₄
Color and Shape:Solid
Molecular weight:336.472
Ref: TM-T37970
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CYM5442 hydrochloride
CAS:
- 1783987-80-3
CYM 5442 HCl: potent, selective S1P1 agonist (EC50 = 1.35 nM), induces MAPK activation & lymphopenia, brain-penetrant.
Formula:C₂₃H₂₈ClN₃O₄
Color and Shape:Solid
Molecular weight:445.94
Ref: TM-T41144
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[D-Trp34]-Neuropeptide Y Acetate
[D-Trp34]-Neuropeptide Y Acetate is a potent Y5 receptor agonist that increases rat food intake; less potent at Y1, Y2, Y4, Y6.
Formula:C₁₉₈H₂₉₃N₅₅O₅₈
Purity:99.73%
Color and Shape:Soild
Molecular weight:4371.78
Ref: TM-TP1984L
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CB2 receptor agonist 2
CAS:
- 1314230-75-5
CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.
Formula:C₃₀H₃₆N₂O₄
Purity:99.75%
Color and Shape:Solid
Molecular weight:488.62
Ref: TM-T22009
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Sibenadet hydrochloride
CAS:
- 154189-24-9
Sibenadet, a D2/beta2-agonist, is potential useful for the treatment of symptoms of chronic obstructive pulmonary disease.
Formula:C₂₂H₂₉ClN₂O₅S₂
Color and Shape:Solid
Molecular weight:501.06
Ref: TM-T28774
+ Info
GLP-1 moiety from Dulaglutide
GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist.
Formula:C₁₄₉H₂₂₁N₃₇O₄₉
Purity:98%
Color and Shape:Solid
Molecular weight:3314.62
Ref: TM-TP1316
+ Info
FK 224
CAS:
- 125787-94-2
FK 224 is an antagonist of tachykinin receptor.
Formula:C₅₄H₇₂N₈O₁₃
Color and Shape:Solid
Molecular weight:1041.213
Ref: TM-T25419
+ Info
FGH31
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].
Formula:C₃₃H₃₆N₄O₂
Purity:98%
Color and Shape:Solid
Molecular weight:520.66
Ref: TM-T79312
+ Info
Tirzepatide TFA
Tirzepatide TFA, a GIP and GLP-1 agonist, targets type 2 diabetes treatment.
Formula:C₂₂₇H₃₄₉F₃N₄₈O₇₀
Color and Shape:Solid
Molecular weight:4927.47
Ref: TM-T76006
+ Info
Cetirizine methyl ester
CAS:
- 83881-46-3
Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.
Formula:C₂₂H₂₇ClN₂O₃
Color and Shape:Solid
Molecular weight:402.91
Ref: TM-T73933
+ Info
SB 699551
CAS:
- 791789-61-2
SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.
Formula:C₃₄H₄₅N₃O
Purity:99.83%
Molecular weight:511.74
Ref: TM-T23325L
+ Info
15(S)-15-methyl Prostaglandin E2
CAS:
- 35700-27-7
15(S)-15-methyl PGE2: A stable PGE2 analog; strong antiulcer with double PGE2 affinity; excels PGE1 in uterine contraction.
Formula:C₂₁H₃₄O₅
Color and Shape:Solid
Molecular weight:366.49
Ref: TM-T36154
+ Info
ent-Prostaglandin E2
CAS:
- 65085-69-0
Enzymatic PGE2 is optically pure; radical peroxidation makes it racemic. In oxidative stress, rac-PGE2 forms via 15-E2t-isoprostane.
Formula:C₂₀H₃₂O₅
Color and Shape:Solid
Molecular weight:352.471
Ref: TM-T35991
+ Info
SRA880 malonate
CAS:
- 573984-99-3
SRA880: non-peptide sst(1) antagonist, low affinity for other sst receptors, binds dopamine D4, boosts SRIF, antidepressant-like effects.
Formula:C₂₉H₃₆N₄O₈
Purity:98%
Color and Shape:Solid
Molecular weight:568.62
Ref: TM-T26225
+ Info
Synephrine hemitartrate
CAS:
- 16589-24-5
Synephrine hemitartrate, an alkaloid from Citrus aurantium, is a sympathomimetic for weight loss, with α and β-adrenergic action.
Formula:C₉H₁₃NO₂C₄H₆O₆
Color and Shape:Solid
Molecular weight:242.26
Ref: TM-T75425
+ Info
SR-140603
CAS:
- 154728-59-3
SR-140603, the less potent enantiomer of SR 140333, is used as the negative control.
Formula:C₃₇H₄₅Cl₃N₂O₂
Purity:98%
Color and Shape:Solid
Molecular weight:656.12
Ref: TM-T26222
+ Info
CB2R agonist 3
CB2R agonist 3, a potent activator of cannabinoid receptor 2 (CB2R), exhibits an EC50 value of 0.37μM, indicative of its significant role in the immune system [
Purity:98%
Color and Shape:Odour Solid
Ref: TM-T82769
+ Info
(R,R)-Palonosetron Hydrochloride
CAS:
- 135729-75-8
(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron
Formula:C₁₉H₂₅ClN₂O
Purity:98%
Color and Shape:Solid
Molecular weight:332.87
Ref: TM-T13437
+ Info
5-methoxy-α-Ethyltryptamine
CAS:
- 4765-10-0
5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. 
Formula:C₁₃H₁₈N₂O
Purity:98.25%
Color and Shape:Solid
Molecular weight:218.29
Ref: TM-T9746
+ Info
J-115814
CAS:
- 329716-61-2
J-115814 is a potent feeding stimulant.
Formula:C₂₉H₃₈ClN₅O₃S
Color and Shape:Solid
Molecular weight:572.16
Ref: TM-T32246
+ Info
Exendin-3/4 (59-86)
Exendin-3/4 (59-86) is a Exendin-4 peptide derivative.
Formula:NA
Purity:98%
Color and Shape:Solid
Molecular weight:3055.49
Ref: TM-TP1366
+ Info
Cafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.
Color and Shape:Odour Liquid
Ref: TM-T9901A-351
+ Info
LHRH
CAS:
- 35263-73-1
Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has
Formula:C₅₅H₇₄N₁₆O₁₄
Purity:98%
Color and Shape:Solid
Molecular weight:1183.27
Ref: TM-T80116
+ Info
Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.
Formula:C₂₂H₂₆FN₅O
Color and Shape:Solid
Molecular weight:395.47
Ref: TM-T74798
+ Info
GPR183 antagonist-3
GPR183 antagonist-3 (compound 33) is an orally active GPR183 antagonist with an IC50 value of 8.7 μM. It demonstrates significant in vitro anti-migration and anti-inflammatory activity in monocytes and can alleviate pathological symptoms in experimental colitis induced by dextran sulfate sodium.
Formula:C₂₁H₁₉BrN₄O₂S
Molecular weight:470.04121
Ref: TM-T209316
+ Info
5-trans Latanoprost (free acid)
CAS:
- 903549-49-5
Latanoprost, a prodrug eye drop, turns into active acid inside the body and treats high eye pressure. Its trans isomer also likely reduces eye pressure.
Formula:C₂₃H₃₄O₅
Color and Shape:Solid
Molecular weight:390.52
Ref: TM-T37214
+ Info
Mini Gastrin I, human
CAS:
- 54405-27-5
Mini Gastrin I, human, is a truncated form of the human gastrin peptide, encompassing amino acids 5-17 of the original sequence.
Formula:C₇₄H₉₉N₁₅O₂₆S
Purity:98%
Color and Shape:Solid
Molecular weight:1646.73
Ref: TM-TP1821
+ Info
des-Gln14-Ghrelin
CAS:
- 293735-04-3
Endogenous rat ghrelin gene variant binds GHS-R1a; strong Ca2+ release (EC50=2.4 nM); boosts GH secretion in vivo.
Formula:C₁₄₂H₂₃₇N₄₃O₄₀
Purity:98%
Color and Shape:Solid
Molecular weight:3186.7
Ref: TM-TP2032
+ Info
Kadsurenin B
CAS:
- 145701-13-9
Kadsurenin B, a platelet-activating factor (PAF) antagonist, exhibits neuroprotective properties and has a broad spectrum of pharmacological research
Formula:C₂₀H₂₂O₅
Color and Shape:Solid
Molecular weight:342.39
Ref: TM-T79948
+ Info
L-796,778
CAS:
- 217480-25-6
L-796,778 is an SST3 agonist and a selective ligand of SST3, which can increase the level of cAMP in the body.
Formula:C₂₉H₄₀N₆O₇
Purity:96.20%
Color and Shape:Solid
Molecular weight:584.66
Ref: TM-T32511
+ Info
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin
CAS:
- 136105-89-0
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), acts as a weak agonist at the antidiuretic receptor but is a potent
Formula:C₄₅H₆₃N₁₅O₁₁S₂
Color and Shape:Solid
Molecular weight:1054.21
Ref: TM-T76509
+ Info
RGS2-Galpha-q interaction-IN-1
RGS2–Galpha-q interaction-IN-1 (Compound AJ-3) is an inhibitor of the RGS2-Galpha-q interaction. It inhibits the growth of cancer cell lines that express RGS2 and has anti-cell migration properties.
Formula:C₃₀H₃₀ClN₇O₃
Color and Shape:Solid
Molecular weight:572.06
Ref: TM-T200859
+ Info
Nadolol
CAS:
- 42200-33-9
Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.
Formula:C₁₇H₂₇NO₄
Purity:99.87% - 99.92%
Color and Shape:White To Off-White Crystalline Powder Solid
Molecular weight:309.40
Ref: TM-T1203
+ Info
GR 64349
CAS:
- 137593-52-3
Potent NK2 agonist, EC50=3.7 nM in rat colon; >1000x selectivity over NK1, >300x over NK3; effective in vivo.
Formula:C₄₂H₆₈N₁₀O₁₁S
Purity:98%
Color and Shape:Solid
Molecular weight:921.12
Ref: TM-TP2023
+ Info
CAY10509
CAS:
- 1245699-47-1
CAY10509 is a PGF2α analogue and acts as an FP receptor inhibitor with an IC50 of 30 nM. It shows potential for use in studying the physiological regulatory mechanisms related to prostaglandins.
Formula:C₂₃H₃₅FO₅S
Color and Shape:Solid
Molecular weight:442.58
Ref: TM-T203384
+ Info
11-deoxy Prostaglandin E1
CAS:
- 37786-00-8
11-deoxy Prostaglandin E1 is a prostaglandin E1 analogue that has bronchodilator activity and can inhibit histamine-induced bronchoconstriction and cause
Formula:C₂₀H₃₄O₄
Color and Shape:Solid
Molecular weight:338.48
Ref: TM-T36770
+ Info
A 77636 hydrochloride
CAS:
- 145307-34-2
A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).
Formula:C₂₀H₂₈ClNO₃
Purity:99.57%
Color and Shape:Solid
Molecular weight:365.89
Ref: TM-T21782
+ Info
Neuropeptide S(Mouse) TFA
Neuropeptide S(Mouse) TFA: Endogenous NPSR agonist, EC50 3 nM, boosts Ca2+, activity, wakefulness, and lowers mouse anxiety.
Formula:C₉₂H₁₅₇F₃N₃₄O₂₉
Color and Shape:Solid
Molecular weight:2296.49
Ref: TM-T75950
+ Info
Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Rat CGRP II TFA: potent vasodilator and CGRP receptor activator for cardiovascular research.
Formula:C₁₆₅H₂₆₈F₃N₅₁O₅₂S₂
Color and Shape:Solid
Molecular weight:3919.33
Ref: TM-T76032
+ Info
L-threo Lysosphingomyelin (d18:1)
CAS:
- 105615-55-2
L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).
Formula:C₂₃H₄₉N₂O₅P
Color and Shape:Solid
Molecular weight:464.62
Ref: TM-T38452
+ Info
Cortistatin-8
CAS:
- 485803-62-1
ghrelin receptor antagonist
Formula:C₄₇H₆₈N₁₂O₉S₂
Purity:98%
Color and Shape:Solid
Molecular weight:1009.25
Ref: TM-TP2236
+ Info
Cortistatin 29
Cortistatin 29: neuropeptide, relieves neuropathic pain, binds SS receptors (IC50: 2.8-13.7 nM), anti-fibrotic.
Formula:C₁₆₁H₂₄₂N₄₆O₄₁S₂
Color and Shape:Solid
Molecular weight:3539.77
Ref: TM-T76331
+ Info
PF-03382792
CAS:
- 1400811-63-3
PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.
Formula:C₂₃H₃₂FN₃O₄
Purity:99.64%
Color and Shape:Solid
Molecular weight:433.52
Ref: TM-T33940
+ Info
(+)-Cloprostenol sodium
CAS:
- 62561-03-9
Cloprostenol sodium is a water-soluble PGF2α analog and FP receptor agonist, promoting luteolysis in rats and hamsters.
Formula:C₂₂H₂₈ClNaO₆
Color and Shape:Solid
Molecular weight:446.9
Ref: TM-T29245
+ Info
Jmv 167
CAS:
- 120775-49-7
Jmv 167 is an antagonist of the Cholecystokinin receptor.
Formula:C₅₁H₆₈N₈O₁₄S
Purity:98%
Color and Shape:Solid
Molecular weight:1049.21
Ref: TM-T24202
+ Info
Mabuterol free base
CAS:
- 56341-08-3
Mabuterol: selective β2 agonist, inhibits isoprenaline, affects rat uterus and rabbit jejunum, alters intestinal propulsion.
Formula:C₁₃H₁₈ClF₃N₂O
Purity:98%
Color and Shape:Solid
Molecular weight:310.74
Ref: TM-T27970
+ Info
QWF
CAS:
- 126088-82-2
Tripeptide SP antagonist (IC50: 90 μM); blocks SP-MRGPR X2 binding and mast cell degranulation; reduces 48/80-induced scratching in mice.
Formula:C₃₈H₄₃N₅O₈
Purity:98%
Color and Shape:Solid
Molecular weight:697.78
Ref: TM-TP1946
+ Info
PF-9184
CAS:
- 1221971-47-6
PF-9184 inhibits human mPGES-1 selectively, with an IC50 of 16.5 nM, and reduces IL-1β-stimulated PGE2 production in vitro.
Formula:C₂₁H₁₄Cl₂N₂O₄S
Purity:97.43%
Color and Shape:Solid
Molecular weight:461.32
Ref: TM-T21738
+ Info
Isoprenaline
CAS:
- 7683-59-2
Isoprenaline is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.
Formula:C₁₁H₁₇NO₃
Purity:99.31%
Color and Shape:Solid
Molecular weight:211.26
Ref: TM-T21411
+ Info
Dopamine D2 receptor agonist-2
CAS:
- 1610591-93-9
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.
Formula:C₂₅H₃₁Cl₂N₅OS
Purity:98.93%
Color and Shape:Soild
Molecular weight:520.52
Ref: TM-T60075
+ Info
β2AR/M-receptor agonist-1
CAS:
- 2230520-62-2
β2AR/M-receptor agonist-1 (example 131), a muscarinic antagonist and β2 adrenoceptor agonist (MABA), exhibits dual potency towards β2 adrenoceptor and
Formula:C₄₃H₅₆BrN₃O₇
Color and Shape:Solid
Molecular weight:806.82
Ref: TM-T74708
+ Info
a-Helical Corticotropin Releasing Factor (12-41)
CAS:
- 158535-55-8
α-Helical CRF (12-41), a 30-aa analog, curbs CRF's ACTH-stimulating effect.
Formula:C₁₅₂H₂₅₁N₄₃O₄₇S₂
Color and Shape:Solid
Molecular weight:3497.01
Ref: TM-T76360
+ Info
NESS 0327
CAS:
- 494844-07-4
NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.
Formula:C₂₄H₂₃Cl₃N₄O
Purity:99.78%
Color and Shape:Solid
Molecular weight:489.82
Ref: TM-T22114
+ Info
Stressin I TFA
Stressin I (Cyclo(31-34)[DPhe12, Nle21, 38, Glu31, Lys34]Ac-hCRF(4-41)) TFA, with a K i of 1.7 nM, is a potent and selective agonist of the CRF1 receptor.
Purity:98%
Color and Shape:Odour Solid
Ref: TM-T81081
+ Info
RC-3095 TFA
CAS:
- 1217463-61-0
RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.
Formula:C₅₈H₈₀F₃N₁₅O₁₁
Purity:98%
Color and Shape:Solid
Molecular weight:1220.34
Ref: TM-TP1701
+ Info
Spantide I TFA
Spantide I TFA is a selective NK1 antagonist (230 nM); much less for NK2 (8150 nM); it modulates cytokines to prevent corneal perforation.
Formula:C₇₇H₁₀₉F₃N₂₀O₁₅
Color and Shape:Solid
Molecular weight:1611.81
Ref: TM-T75837
+ Info
Proglumide hemicalcium
CAS:
- 85068-56-0
Proglumide hemicalcium is a antagonist of nonpeptide and orally active cholecystokinin (CCK)-A/B receptors, has antiepileptic and antioxidant activities.
Formula:C₁₈H₂₈CaN₂O₄
Purity:98%
Color and Shape:Solid
Molecular weight:376.51
Ref: TM-T12544
+ Info
Kisspeptin 234
CAS:
- 1145998-81-7
Kisspeptin receptor antagonist; blocks kisspeptin-10 effects on IP (IC50 = 7 nM) and GnRH release.
Formula:C₆₃H₇₈N₁₈O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1295.42
Ref: TM-TP1896
+ Info
OXA(17-33) TFA
OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).
Formula:C₈₁H₁₂₆F₃N₂₃O₂₄
Color and Shape:Solid
Molecular weight:1863
Ref: TM-T75922
+ Info
BMS-604992 dihydrochloride
CAS:
- 1469750-46-6
BMS-604992 dihydrochloride is a selective GHSR agonist with high affinity (Ki=2.3 nM) and potent activity (EC50=0.4 nM), stimulating rodent appetite.
Formula:C₂₄H₃₃Cl₂N₇O₅
Color and Shape:Solid
Molecular weight:570.47
Ref: TM-T38959
+ Info
ELA-21 (human)
CAS:
- 2245073-05-4
Apelin receptor agonist with high affinity for normal/PAH hearts (pKi 9.31/9.46). Blocks cAMP, promotes β-arrestin in vitro. Part of ELA-32.
Formula:C₁₁₂H₁₈₄N₄₀O₂₅S₃
Purity:98%
Color and Shape:Solid
Molecular weight:2587.12
Ref: TM-TP2096
+ Info
A3AR agonist 2
Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM.
Formula:C₃₄H₃₄N₆O₆
Purity:98%
Color and Shape:Solid
Molecular weight:622.67
Ref: TM-T79373
+ Info
Misoprostol acid
CAS:
- 112137-89-0
Misoprostol acid is an active metabolite of Misoprostol,can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers.
Formula:C₂₁H₃₆O₅
Purity:98%
Color and Shape:Solid
Molecular weight:368.51
Ref: TM-T12047
+ Info
IRL-3630
CAS:
- 173189-01-0
IRL 3460 is an enantiomer.
Formula:C₃₁H₄₀N₄O₆S
Purity:98%
Color and Shape:Solid
Molecular weight:596.74
Ref: TM-T25541
+ Info
Lisuride maleate
CAS:
- 19875-60-6
Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.
Formula:C₂₄H₃₀N₄O₅
Purity:99.85%
Color and Shape:Solid
Molecular weight:454.52
Ref: TM-T8775
+ Info
SB 201146
CAS:
- 141311-11-7
SB 201146 is a leukotriene B4 antagonist with high affinity.
Formula:C₃₀H₃₅LiN₂O₅S
Color and Shape:Solid
Molecular weight:542.61
Ref: TM-T28667
+ Info
Guanylin (mouse, rat)
CAS:
- 145257-03-0
Guanylin (mouse, rat), a peptide consisting of 15 amino acids, acts as an activator of intestinal guanylate cyclase and is utilized in diarrhea research [1].
Formula:C₆₀H₉₀N₁₆O₂₂S₄
Purity:98%
Color and Shape:Solid
Molecular weight:1515.71
Ref: TM-T80150
+ Info
Parstatin(mouse)
CAS:
- 1065756-01-5
Peptide inhibits endothelial migration/proliferation (IC50 ~20μM), induces cell cycle arrest, triggers apoptosis, and has cardioprotective effects.
Formula:C₁₈₉H₃₂₆N₅₈O₅₇S₃
Purity:98%
Color and Shape:Solid
Molecular weight:4419.19
Ref: TM-TP1966
+ Info
Pancreatic Polypeptide, bovine
CAS:
- 179986-89-1
Agonist at Y4 neuropeptide Y receptors.
Formula:C₁₈₆H₂₈₇N₅₃O₅₆S₂
Purity:98%
Color and Shape:Solid
Molecular weight:4225.78
Ref: TM-TP1731
+ Info
Kinetensin
CAS:
- 103131-69-7
Kinetensin is a neurotensin-like peptide.
Formula:C₅₆H₈₅N₁₇O₁₁
Purity:98%
Color and Shape:White Lyophilised Solid
Molecular weight:1172.38
Ref: TM-TP1116
+ Info
Amylin, amide, rat
CAS:
- 124447-81-0
Amylin: peptide, 50% similar to CGRP, found with somatostatin in stomach cells, reduces acid secretion in mice.
Formula:C₁₆₇H₂₇₂N₅₂O₅₃S₂
Purity:99.92%
Color and Shape:Solid
Molecular weight:3920.44
Ref: TM-TP1232
+ Info
Guanylin TFA (mouse,rat)
Guanylin (mouse, rat) TFA is a peptide composed of 15 amino acids and acts as an activator of intestinal guanylate cyclase. This compound is utilized in research related to diarrhea.
Formula:C₆₀H₉₀N₁₆O₂₂S₄·xC₂HF₃O₂
Color and Shape:Solid
Molecular weight:1515.71 (free base)
Ref: TM-TP2847
+ Info
Y1 receptor antagonist 1 formic
H 409-22 isomer formic, a formate salt of Y1 receptor antagonist 1, is an antagonist of the neuropeptide Y1 receptor (neuropeptide Y1 receptor). This compound effectively blocks the actions of the receptor, playing a crucial role in modulating physiological responses.
Formula:C₂₉H₃₅N₅O₅
Color and Shape:Solid
Molecular weight:533.62
Ref: TM-T200259
+ Info
PEN (human)
CAS:
- 597578-70-6
PEN (human) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.
Formula:C₉₇H₁₅₉N₂₇O₃₂
Purity:98%
Color and Shape:Solid
Molecular weight:2215.49
Ref: TM-TP1949
+ Info
NF546 hydrate
NF546 (hydrate), a selective non-nucleotide P2Y11 agonist, exhibits a pEC50 value of 6.27 and induces interleukin-8 secretion from human monocyte-derived
Formula:C₄₇H₄₄N₆Na₄O₁₇P₄·5H₂O
Purity:98%
Color and Shape:Solid
Molecular weight:1424.01
Ref: TM-T78079
+ Info
HAEGTFT
CAS:
- 926018-95-3
HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide.
Formula:C₃₃H₄₇N₉O₁₂
Purity:98%
Color and Shape:Solid
Molecular weight:761.78
Ref: TM-TP1419
+ Info
HHS-0701
CAS:
- 2851993-91-2
HHS-0701: SuTEx ligand, strong PTGR2 inhibitor, blocks 15-Keto-PGE2 metabolism.
Formula:C₂₀H₂₀N₄O₃S
Purity:97.24%
Color and Shape:Soild
Molecular weight:396.46
Ref: TM-T67766
+ Info
Cinanserin hydrochloride
CAS:
- 54-84-2
Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.
Formula:C₂₀H₂₅ClN₂OS
Purity:99.57%
Color and Shape:Solid
Molecular weight:376.94
Ref: TM-T14968
+ Info
Pasireotide ditrifluoroacetate
Pasireotide is a stable cyclohexapeptide somatostatin mimic.
Formula:C₆₂H₆₈F₆N₁₀O₁₃
Purity:98%
Color and Shape:Solid
Molecular weight:1275.25
Ref: TM-T13811
+ Info
TGR5 agonist 7
TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.
Formula:C₃₇H₅₉N₂NaO₉S
Color and Shape:Solid
Molecular weight:730.93
Ref: TM-T203565
+ Info
Tetrapeptide-1
CAS:
- 1632354-04-1
Tetrapeptide-1 is a bioactive peptide renowned for its antioxidant properties and has been cited as an ingredient in cosmetics [1].
Formula:C₂₀H₃₆N₄O₆
Purity:98%
Color and Shape:Solid
Molecular weight:428.52
Ref: TM-T80202
+ Info
Phoenixin-14 TFA
Phoenixin-14 TFA (PNX-14 TFA) is an endogenous neuropeptide that can modulate GnRH receptor expression and exerts anxiolytic effects.
Formula:C₇₅H₁₁₀N₁₈O₂₀·xC₂HF₃O₂
Purity:99.11%
Color and Shape:Solid
Molecular weight:1583.78 (free base)
Ref: TM-T81485
+ Info
6-Fluoro-N,N-diethyltryptamine
CAS:
- 2836-69-3
6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.
Formula:C₁₄H₁₉FN₂
Color and Shape:Solid
Molecular weight:234.31
Ref: TM-T203176
+ Info
15(R)-17-phenyl trinor Prostaglandin F2α
CAS:
- 41639-71-8
17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular
Formula:C₂₃H₃₂O₅
Color and Shape:Solid
Molecular weight:388.5
Ref: TM-T37930
+ Info
[D-Pro2] Spantide I TFA
[D-Pro2] Spantide I TFA is an analog of Spantide I, a selective antagonist of the NK1 receptor [1].
Formula:C₇₅H₁₀₈N₂₀O₁₃·xC₂HF₃O₂
Purity:98%
Color and Shape:Solid
Ref: TM-T80031
+ Info
RFRP-3(human)
CAS:
- 311309-27-0
NPFF1 receptor agonist, IC50 0.7 nM, blocks cAMP by forskolin. A GnIH homolog, it inhibits GnRH neuron activity.
Formula:C₄₅H₇₂N₁₄O₁₀
Purity:98%
Color and Shape:Solid
Molecular weight:969.15
Ref: TM-TP1936
+ Info
Des His1, Glu8 Exendin-4
Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP1R) antagonist that regulates blood glucose and is used in the study of diabetes and obesity.
Formula:C₁₇₉H₂₇₇N₄₇O₅₉S
Purity:99.92%
Color and Shape:Solid
Molecular weight:4063.46
Ref: TM-T76291
+ Info
Semaglutide TFA
Semaglutide TFA is a glucagon-like peptide-1 congener that induces weight loss, lowers blood glucose levels and reduces cardiovascular risk in diabetic patients
Formula:C₁₈₉H₂₉₀F₃N₄₅O₆₁
Purity:99.69%
Color and Shape:Solid
Molecular weight:4225.6482
Ref: TM-T12878
+ Info
(R)-CJ 11974
CAS:
- 187281-35-2
(R)-CJ 11974: non-peptide NK1 receptor antagonist, may relieve pain and prevent chemo-induced vomiting.
Formula:C₃₁H₃₈N₂O
Purity:97.15%
Color and Shape:Soild
Molecular weight:454.65
Ref: TM-T68068L
+ Info
tetranor-PGJM
CAS:
- 1352751-83-7
Tetranor-PGJM is a metabolite of prostaglandin D2 and is associated with the anti-inflammatory effects of curcumin.
Formula:C₁₆H₂₂O₆
Color and Shape:Solid
Molecular weight:310.346
Ref: TM-T38307
+ Info
Propranolol hydrochloride
CAS:
- 318-98-9
Propranolol hydrochloride is a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse
Formula:C₁₆H₂₂ClNO₂
Purity:99.94% - >99.99%
Color and Shape:White Or Almost White Powder White Powder
Molecular weight:295.80
Ref: TM-T0812
+ Info
[Ala11,D-Leu15]-Orexin B(human)
CAS:
- 532932-99-3
OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).
Formula:C₁₂₀H₂₀₆N₄₄O₃₅S
Purity:98%
Color and Shape:Solid
Molecular weight:2857.28
Ref: TM-TP1975
+ Info
HCGRP-(8-37)
CAS:
- 119911-68-1
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist
Formula:C₁₃₉H₂₃₀N₄₄O₃₈
Purity:98%
Color and Shape:Solid
Molecular weight:3125.59
Ref: TM-TP1134
+ Info
20-SOLA
20-SOLA is the first water-soluble 20-HETE antagonist with oral bioavailability. It significantly improves blood pressure changes and kidney damage associated with the streptozotocin (STZ) diabetic mouse model. Additionally, 20-SOLA acts as a GPR75 receptor blocker. This compound is useful in research related to cardiovascular pathology.
Formula:C₃₃H₆₂O₉
Molecular weight:602.43938
Ref: TM-T208783
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MRS7925
MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis
Formula:C₂₀H₂₆IN₅O₃
Purity:98%
Color and Shape:Solid
Molecular weight:511.36
Ref: TM-T79326
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Cetirizine Impurity D
CAS:
- 346451-15-8
Cetirizine Impurity D, an antihistamine derivative, acts as a long-lasting H1-receptor antagonist with antiallergic effects.
Formula:C₃₀H₂₈Cl₂N₂
Color and Shape:Solid
Molecular weight:487.46
Ref: TM-T40430
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Prolactin Releasing Peptide (1-31), human
CAS:
- 215510-22-8
Human Prolactin Releasing Peptide (1-31) is a potent GPR10 agonist; Ki values are 1.03 nM (human) and 0.33 nM (rat).
Formula:C₁₆₀H₂₅₂N₅₆O₄₂S
Purity:98%
Color and Shape:Solid
Molecular weight:3664.15
Ref: TM-TP1769
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GI-560192
CAS:
- 301326-41-0
GI-560192 (RL-0070933), a potent smo modulator, EC50: 0.02µM; affects smoothened in cilia via hedgehog signaling.
Formula:C₂₀H₁₆N₂O₂
Purity:99.53%
Color and Shape:Soild
Molecular weight:316.35
Ref: TM-T64351
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Brombuterol hydrochloride
CAS:
- 21912-49-2
Brombuterol is an agonist of the β2-adrenergic receptor (β2-AR).1It has been used as an illicit feed additive to increase the muscle-to-fat ratio of livestock.
Formula:C₁₂H₁₉Br₂ClN₂O
Color and Shape:Solid
Molecular weight:402.56
Ref: TM-T37848
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WZ4141
CAS:
- 1222776-76-2
WZ4141 is an intermediate in compound synthesis.
Formula:C₁₆H₁₃N₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:279.29
Ref: TM-T19604
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SAR247799
CAS:
- 1315311-14-8
SAR247799 is a selective and G-protein-biased S1P1 agonist that activates downstream G-protein signaling pathways more preferentially on endothelial cells.
Formula:C₂₁H₁₆ClN₃O₅
Color and Shape:Solid
Molecular weight:425.82
Ref: TM-T38716
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Eplivanserin (mixture)
CAS:
- 130581-13-4
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,
Formula:C₁₉H₂₁FN₂O₂
Color and Shape:Solid
Molecular weight:328.387
Ref: TM-T11216
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LAS101057
CAS:
- 925676-48-8
LAS101057 is a novel orally available and potent and selective A2B receptor antagonist for the study of asthma.
Formula:C₁₈H₁₄FN₅O
Purity:99.03% - >99.99%
Color and Shape:Solid
Molecular weight:335.34
Ref: TM-T15715
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Levomepromazine
CAS:
- 60-99-1
Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.
Formula:C₁₉H₂₄N₂OS
Purity:99.15%
Color and Shape:Solid
Molecular weight:328.47
Ref: TM-T15743
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SANT 2
CAS:
- 329196-48-7
SANT 2 is a Hedgehog (Hh) signaling pathway antagonist with potential anti-inflammatory and anti-cancer activities.
Formula:C₂₆H₂₆ClN₃O₄
Purity:99.23%
Color and Shape:Solid
Molecular weight:479.96
Ref: TM-T23307
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4-Hydroxyatomoxetine D3
CAS:
- 1217686-14-0
4-Hydroxyatomoxetine D3, a deuterium variant, is Atomoxetine's active metabolite, metabolized by CYP2D6, an adrenergic reuptake blocker.
Formula:C₁₇H₂₁NO₂
Purity:98%
Color and Shape:Solid
Molecular weight:274.37
Ref: TM-T10144
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SLIGRL-NH2
CAS:
- 171436-38-7
SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.
Formula:C₂₉H₅₆N₁₀O₇
Purity:98.29%
Color and Shape:Solid
Molecular weight:656.82
Ref: TM-TP1046
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Docosahexaenoic acid ethyl ester
CAS:
- 81926-94-5
Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) enhances 6-hydroxydopamine-induced neuronal damage by inducing lipid peroxidation in the mouse striatum, and can be used to study oxidative diseases of the retina or neurons.
Formula:C₂₄H₃₆O₂
Color and Shape:Solid
Molecular weight:356.54
Ref: TM-T41321
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Clothiapine
CAS:
- 2058-52-8
Clothiapine is an atypical antipsychotic of the dibenzothiazepine chemical class.
Formula:C₁₈H₁₈ClN₃S
Purity:99.93%
Color and Shape:Solid
Molecular weight:343.87
Ref: TM-T23900
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Cariprazine D6
CAS:
- 1308278-67-2
Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
Formula:C₂₁H₂₆D₆Cl₂N₄O
Purity:98%
Color and Shape:Solid
Molecular weight:433.45
Ref: TM-T10681
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BW 723C86
CAS:
- 160521-72-2
BW 723C86 is a 5-HT2B receptor agonist with anxiolytic effects, inducing overeating and reduced grooming in rats, useful in studying neurological disorders.
Formula:C₁₆H₁₉ClN₂OS
Purity:99.35%
Color and Shape:Solid
Molecular weight:322.85
Ref: TM-T21625
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Sumatriptan
CAS:
- 103628-46-2
Sumatriptan (GR 43175 free base) is a 5-HT1 receptor agonist with anti-inflammatory activity used in acute migraine and acute myocardial infarction.
Formula:C₁₄H₂₁N₃O₂S
Purity:99.93%
Color and Shape:White To Off-White Crystalline Powder
Molecular weight:295.4
Ref: TM-T23405
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ML224
CAS:
- 1338824-21-7
ML224 (NCGC00242364) is a TSHR antagonist for the treatment of Graves' orbital disease and Graves' hyperthyroidism.
Formula:C₃₁H₃₁N₃O₅
Purity:99.14%
Color and Shape:Solid
Molecular weight:525.59
Ref: TM-T16106
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Ramelteon-d5
CAS:
- 1134159-63-9
Ramelteon-d5 is a deuterated compound of Ramelteon.
Formula:C₁₆H₁₆D₅NO₂
Color and Shape:Solid
Molecular weight:264.37
Ref: TM-TMIH-0486
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Tulobuterol-d9 HCl
CAS:
- 1325559-14-5
Tulobuterol-d9 HCl is a deuterated compound of Tulobuterol HCl.
Formula:C₁₂H₁₀D₉Cl₂NO
Molecular weight:273.25
Ref: TM-TMIH-0589
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Paliperidone Palmitate
CAS:
- 199739-10-1
Paliperidone: atypical antipsychotic, dopamine & serotonin antagonist, affects α1/α2 adrenergic and H1 histamine receptors.
Formula:C₃₉H₅₇FN₄O₄
Purity:98%
Color and Shape:Solid
Molecular weight:664.89
Ref: TM-T19950
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3-Hydroxy agomelatine D3
CAS:
- 1079774-23-4
3-Hydroxy agomelatine D3 is a deuterated metabolite of Agomelatine and a 5-HT2C antagonist (IC50: 3.2 μM, Ki: 1.8 μM).
Formula:C₁₅H₁₇NO₃
Purity:98%
Color and Shape:Solid
Molecular weight:262.32
Ref: TM-T10113
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Cetirizine D4
CAS:
- 1219803-84-5
Cetirizine D4 is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist.
Formula:C₂₁H₂₅ClN₂O₃
Purity:98%
Color and Shape:Solid
Molecular weight:392.91
Ref: TM-T10769
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PD176252
CAS:
- 204067-01-6
PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.
Formula:C₃₂H₃₆N₆O₅
Purity:99.18%
Color and Shape:Solid
Molecular weight:584.67
Ref: TM-T16449
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Agomelatine-d6
CAS:
- 1079389-42-6
Agomelatine D6 (S-20098 D6) is a deuterium-labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors.
Formula:C₁₅H₁₇NO₂
Purity:98%
Color and Shape:Solid
Molecular weight:249.34
Ref: TM-T10266
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Bombesin
CAS:
- 31362-50-2
Bombesin: 14-amino acid peptide from toad skin with two mammalian homologs, neuromedin B and gastrin-releasing peptide.
Formula:C₇₁H₁₁₀N₂₄O₁₈S
Color and Shape:While Lyophilized Powder
Molecular weight:1619.85
Ref: TM-TP1281
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Thioridazine
CAS:
- 50-52-2
Thioridazine: an antipsychotic, anti-anxiety drug, blocks dopamine D2, PI3K-Akt-mTOR; halts angiogenesis, kills cancer cells, targets CSCs.
Formula:C₂₁H₂₆N₂S₂
Color and Shape:Solid
Molecular weight:370.57
Ref: TM-T61476
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Fipexide hydrochloride
CAS:
- 34161-23-4
Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.
Formula:C₂₀H₂₂Cl₂N₂O₄
Color and Shape:Solid
Molecular weight:425.31
Ref: TM-T22332
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Granisetron
CAS:
- 109889-09-0
Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
Formula:C₁₈H₂₄N₄O
Color and Shape:Solid
Molecular weight:312.41
Ref: TM-T22340
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Aripiprazole (D8)
CAS:
- 1089115-06-9
Aripiprazole D8 (OPC-14597 D8) is the deuterium-labeled Aripiprazole. Aripiprazole is a human 5-HT1A receptor partial agonist (Ki: 4.2 nM).
Formula:C₂₃H₂₇Cl₂N₃O₂
Purity:98%
Color and Shape:Solid
Molecular weight:456.44
Ref: TM-T10368
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Zilpaterol-d7
CAS:
- 1217818-36-4
Zilpaterol-d7 (trans-(±)-Zilpaterol-d7) is a deuterium-labeled version of Zilpaterol, a β-adrenergic receptor agonist.
Formula:C₁₄H₁₂D₇N₃O₂
Color and Shape:Solid
Molecular weight:268.36
Ref: TM-TMIH-0611
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Ivabradine-d6 hydrochloride
CAS:
- 2070009-63-9
Ivabradine HCl: novel If inhibitor, IC50 2.9 μM; lowers heart rate. Ivabradine D6 HCl is its deuterium variant.
Formula:C₂₇H₃₇ClN₂O₅
Purity:98%
Color and Shape:Solid
Molecular weight:511.08
Ref: TM-T11694
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MRGPRX4 modulator-2
CAS:
- 2492595-24-9
MRGPRX4 modulator-2 (compound 1-55) is a highly potent antagonist of MRGPRX4 with an IC50 value of less than 100 nM. Its notable applications include research on autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson's Syndrome, and various chronic itch conditions [1].
Formula:C₁₅H₉ClF₄O₃
Purity:99.24%
Color and Shape:Solid
Molecular weight:348.68
Ref: TM-T61183
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Emedastine Difumarate
CAS:
- 87233-62-3
Emedastine Difumarate, an H1 receptor blocker for allergic conjunctivitis, reduces histamine-induced eye inflammation.
Formula:C₂₅H₃₄N₄O₉
Color and Shape:Solid
Molecular weight:534.56
Ref: TM-T21388
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Cefaclor
CAS:
- 53994-73-3
Cefaclor (Panoral) is a cephalosporin antibiotic.
Formula:C₁₅H₁₄ClN₃O₄S
Purity:99.03% - 99.98%
Color and Shape:Solid
Molecular weight:367.81
Ref: TM-T6436
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BMS-986224
CAS:
- 2055200-88-7
BMS-986224 is an orally active, potent and selective APJ receptor agonist.BMS-986224 is a candidate compound for the treatment of heart failure.
Formula:C₂₄H₂₃ClN₄O₆
Purity:98.61% - 99.67%
Color and Shape:Solid
Molecular weight:498.92
Ref: TM-T39448
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PSB-0739
CAS:
- 1052087-90-7
PSB-0739 Selective platelet P2Y12 receptor antagonist characterized by competitive binding with antithrombotic and platelet aggregation modulating effects.
Formula:C₂₆H₁₇N₃Na₂O₈S₂
Purity:98%
Color and Shape:Solid
Molecular weight:609.54
Ref: TM-T23195
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GR79236
CAS:
- 124555-18-6
GR79236 is an effective and selective adenosine A1 receptor agonist (Ki: 3.1 nM) that has analgesic and anti-inflammatory actions.
Formula:C₁₅H₂₁N₅O₅
Color and Shape:Solid
Molecular weight:351.36
Ref: TM-TQ0136
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4,4-Diphenylbutylamine hydrochloride
CAS:
- 22101-90-2
4,4-Diphenylbutylamine shows affinity for the 5-HT2A and H1 receptors with Kis of 2589 and 1670 nM, respectively[1].
Formula:C₁₆H₂₀ClN
Color and Shape:Solid
Molecular weight:261.79
Ref: TM-T37372
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SYL-4
CAS:
- 6222-65-7
SYL-4 is a potential P2Y12 receptor antagonist with a Ki value of 7.35 ± 1.72 for use in synthetic dyes.
Formula:C₂₀H₁₅N₃O₅S
Purity:95.76%
Color and Shape:Soild
Molecular weight:409.42
Ref: TM-T83637
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Omidenepag
CAS:
- 1187451-41-7
Omidenepag (UR-7276) is an EP2 agonist and a novel topical ocular hypotensive agent.Omidenepag can be used to study glaucoma and hypertension.
Formula:C₂₃H₂₂N₆O₄S
Purity:99.67% - 99.77%
Color and Shape:Solid
Molecular weight:478.52
Ref: TM-T16389
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Altanserin
CAS:
- 76330-71-7
Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.
Formula:C₂₂H₂₂FN₃O₂S
Color and Shape:Solid
Molecular weight:411.49
Ref: TM-T29913
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ML 00253764
CAS:
- 681847-92-7
melanocortin MC4 receptor antagonist
Formula:C₁₈H₁₈BrFN₂O
Color and Shape:Solid
Molecular weight:377.25
Ref: TM-T22989
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3-O-Methyldopa-d3
CAS:
- 586954-09-8
3-O-Methyldopa-d3 is a deuterated compound of 3-O-Methyldopa. 3-O-Methyldopa has a CAS number of 300-48-1.
Formula:C₁₀H₁₀D₃NO₄
Molecular weight:214.23
Ref: TM-TMIH-0049
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SB-674042
CAS:
- 483313-22-0
SB-674042 is a nonpeptide dual antagonist of the appetite peptides OX1 and OX2 receptors.SB-674042 is used in the treatment of depression.
Formula:C₂₄H₂₁FN₄O₂S
Purity:99.9%
Color and Shape:Solid
Molecular weight:448.51
Ref: TM-T16854
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Fexofenadine-d6
CAS:
- 548783-71-7
Fexofenadine D6 is an antihistamine pharmaceutical drug.Fexofenadine D6 is deuterium labeled is Fexofenadine.
Formula:C₃₂H₃₉NO₄
Purity:98%
Color and Shape:Solid
Molecular weight:507.69
Ref: TM-T11276
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Argipressin
CAS:
- 113-79-1
Argipressin is a vasoconstrictive and antidiuretic hormone, binding to V1 receptors with Kd ~1.4 nM in rat heart and aortic cells.
Formula:C₄₆H₆₅N₁₅O₁₂S₂
Purity:98%
Color and Shape:White Powder
Molecular weight:1084.23
Ref: TM-T7434
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BMS-986020 sodium
CAS:
- 1380650-53-2
BMS-986020 sodium (AM152 sodium) is a high-affinity LPA1 antagonist for investigating idiopathic pulmonary fibrosis.
Formula:C₂₉H₂₅N₂NaO₅
Color and Shape:Solid
Molecular weight:504.51
Ref: TM-T63439
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GLP-1R modulator C5
CAS:
- 421578-93-0
GLP-1R modulator C5 is a GLP-1R modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.
Formula:C₂₄H₂₁NO₃
Purity:99.59%
Color and Shape:Solid
Molecular weight:371.43
Ref: TM-T61483
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GLP-1R modulator L7-028
CAS:
- 2648317-95-5
GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.
Formula:C₂₄H₂₈N₂O₃
Purity:98.76% - >99.99%
Color and Shape:Solid
Molecular weight:392.49
Ref: TM-T40279
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(S)-ZINC-3573
CAS:
- 2095596-11-3
(S)-ZINC 3573 is a negative control for (R)-ZINC 3573. (S)-ZINC 3573 displays no activity at MRGPRX2 at concentrations below 100 μM.
Formula:C₁₈H₂₁N₅
Color and Shape:Solid
Molecular weight:307.401
Ref: TM-T41187
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Calcium-Sensing Receptor Antagonists I
CAS:
- 478963-79-0
Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.
Formula:C₂₃H₂₄N₂O₂
Color and Shape:Solid
Molecular weight:360.45
Ref: TM-T10665
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Antazoline phosphate
CAS:
- 154-68-7
Antazoline phosphate: H1 histamine receptor antagonist with anticholinergic effects, eases allergies.
Formula:C₁₇H₂₂N₃O₄P
Purity:98%
Color and Shape:Coa
Molecular weight:363.35
Ref: TM-T21020
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Ipragliflozin (L-Proline)
CAS:
- 951382-34-6
Ipragliflozin is a highly potent and selective SGLT2 inhibitor with an IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6.
Formula:C₂₆H₃₀FNO₇S
Color and Shape:Solid
Molecular weight:519.58
Ref: TM-T11667
+ Info
Bradykinin (1-5)
CAS:
- 23815-89-6
Bradykinin (1-5), a stable metabolite of BK produced by ACE, serves as a marker for in vivo BK generation.
Formula:C₂₇H₄₀N₈O₆
Color and Shape:Solid
Molecular weight:572.66
Ref: TM-TP1725