GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(942 products)
- Adenosine Receptor(242 products)
- Adrenergic Receptor(2,949 products)
- Bombesin Receptor(30 products)
- Bradykinin Receptor(59 products)
- CXCR(149 products)
- CaSR(32 products)
- Cannabinoid Receptor(195 products)
- Dopamine Receptor(410 products)
- Endothelin Receptor(75 products)
- GNRH Receptor(73 products)
- GPCR19(31 products)
- GRK(32 products)
- GTPase(21 products)
- Glucagon Receptor(166 products)
- Hedgehog/Smoothened(45 products)
- Histamine Receptor(359 products)
- LPA Receptor(21 products)
- Melatonin Receptor(24 products)
- OX Receptor(40 products)
- Opioid Receptor(298 products)
- PAFR(11 products)
- PKA(49 products)
- S1P Receptor(17 products)
- SGLT(30 products)
- Sigma receptor(46 products)
Show 18 more subcategories
Found 5378 products of "GPCR/G-Protein"
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tcY-NH2 TFA(327177-34-4 free base)
<p>tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.</p>Formula:C42H50F3N7O9Purity:>99.99%Color and Shape:SolidMolecular weight:853.9PD-168077 maleate
CAS:<p>PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM)</p>Formula:C24H26N4O5Purity:99.13%Color and Shape:SolidMolecular weight:450.49IPSU
CAS:<p>IPSU is an antagonist of OX2 receptor. IPSU Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors.</p>Formula:C23H27N5O2Purity:97.05%Color and Shape:SolidMolecular weight:405.498-Cyclopentyl-1,3-dimethylxanthine
CAS:<p>8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a potent antagonist of adenosine A1 receptor.</p>Formula:C12H16N4O2Purity:98.58% - >99.99%Color and Shape:SolidMolecular weight:248.283-AQC
CAS:<p>3-AQC is a competitive antagonist of 5-HT3.</p>Formula:C20H21N5O4Purity:99.45%Color and Shape:SolidMolecular weight:395.41CHEMBL241987
CAS:<p>CHEMBL241987 targets the Adenosine receptor A3 (human)</p>Formula:C16H11N3OPurity:99.81%Color and Shape:SolidMolecular weight:261.28Avexitide
CAS:<p>Avexitide (Exendin-3 (9-39) amide) (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.</p>Formula:C149H234N40O47SPurity:98% - 99.65%Color and Shape:SolidMolecular weight:3369.76BD1063 dhydrochloride
CAS:BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).Formula:C13H20Cl4N2Purity:99.52% - ≥95%Color and Shape:SolidMolecular weight:346.12Methyldopa hydrate
CAS:<p>Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension.</p>Formula:C10H13NO4H2OPurity:99.67%Color and Shape:White SolidMolecular weight:238.24Tiprenolol
CAS:<p>Tiprenolol is a beta adrenergic receptor antagonist.[1]</p>Formula:C13H21NO2SPurity:99.43%Color and Shape:SolidMolecular weight:255.38BAR 501 impurity
CAS:<p>BAR 501 impurity 在 BAR501 制剂中发现的一种杂质，可作为 G 蛋白偶联胆汁酸激活受体 (GP-BAR1) 的激动剂。 BAR501 杂质 (10 µM) 在 GP-BAR1 报告基因检测中诱导荧光素酶活性增加 150%。</p>Formula:C26H46O3Purity:98.78%Color and Shape:SolidMolecular weight:406.64Conopressin S acetate(111317-90-9 free base)
<p>Conopressin S acetate(111317-90-9 free base) (Con-S acetate) is a natural product isolated from Conus striatus, shows high affinity with vasopressin V1b</p>Formula:C43H77N17O12S2Purity:99.79%Color and Shape:SolidMolecular weight:1088.32AVN-101
CAS:<p>AVN-101 is a very potent 5-HT7 receptor antagonist.Cost-effective and quality-assured.</p>Formula:C21H25ClN2Purity:99.61%Color and Shape:SolidMolecular weight:340.89Canagliflozin
CAS:<p>Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.</p>Formula:C24H25FO5SPurity:98.01% - >99.99%Color and Shape:SolidMolecular weight:444.52Veralipride
CAS:<p>Veralipride ((±)-Veralipride) is an antagonist of D2 receptor.</p>Formula:C17H25N3O5SPurity:99.65%Color and Shape:SolidMolecular weight:383.46Betahistine dihydrochloride
CAS:<p>Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator.</p>Formula:C8H14Cl2N2Purity:99.34% - 99.88%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:209.12Mosapride
CAS:<p>Mosapride (AS-4370) is a selective 5HT4 agonist</p>Formula:C21H25ClFN3O3Purity:99.56%Color and Shape:White To Off-White Crystalline SolidMolecular weight:421.89KH7
CAS:<p>KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific.</p>Formula:C17H15BrN4O2SPurity:98.43%Color and Shape:SolidMolecular weight:419.3ONO-7300243
CAS:<p>ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).</p>Formula:C28H31NO5Purity:99.66%Color and Shape:SolidMolecular weight:461.55Thrombin Receptor Activator for Peptide
<p>Thrombin Receptor Activator (TRAP) or Coagulation Factor II (1-5), used in CHD research.</p>Formula:C32H51F3N8O9Purity:99.88%Color and Shape:SolidMolecular weight:748.79NAN-190 hydrobromide
CAS:<p>NAN-190 hydrobromide is an antagonist of serotonin receptor 5-HT.</p>Formula:C23H28BrN3O3Purity:95.20%Color and Shape:SolidMolecular weight:474.39HAEGTFT acetate(926018-95-3 free base)
<p>HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.</p>Formula:C35H51N9O14Purity:>99.99%Color and Shape:SolidMolecular weight:821.84Linzagolix
CAS:<p>Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei</p>Formula:C22H15F3N2O7SPurity:99.33%Color and Shape:SolidMolecular weight:508.42ACH-000143
CAS:<p>ACH-000143 是一种可口服的褪黑素受体激动剂，对 MT1 和 MT2 的EC50值分别为0.06 和0.32 nM。</p>Formula:C13H16ClN3O3Purity:98.15%Color and Shape:SolidMolecular weight:297.74Medetomidine hydrochloride
CAS:<p>Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.</p>Formula:C13H16N2·HClPurity:99.96%Color and Shape:White Or Off White Crystalline PowderMolecular weight:236.74GLP-1 receptor agonist 9
CAS:<p>1H-Benzimidazole-6-carboxylic acid is a GLP-1 receptor agonist.</p>Formula:C32H31ClFN3O5Purity:98%Color and Shape:SolidMolecular weight:592.06Ablukast
CAS:<p>Ablukast (Ro 23-3544) is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic.</p>Formula:C28H34O8Purity:98.58%Color and Shape:SolidMolecular weight:498.56Betaxolol
CAS:<p>Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.</p>Formula:C18H29NO3Purity:99.01%Color and Shape:White Crystalline SolidMolecular weight:307.43GW842166X
CAS:<p>GW842166X: Potent CB2 agonist, EC50=63 nM, inactive at CB1, in Phase 2 trials.</p>Formula:C18H17Cl2F3N4O2Purity:99.47%Color and Shape:SolidMolecular weight:449.25Thonzylamine
CAS:<p>Thonzylamine is an antihistamine/anticholinergic, combined with Clofedanol or Phenylephrine for cold, hay fever, or allergy relief.</p>Formula:C16H22N4OPurity:99.45%Color and Shape:SolidMolecular weight:286.37LML134
CAS:<p>LML134 (LML-134) is an inverse agonist of Histamine 3 receptor (H3R)(hH3R cAMP and hH3R bdg with Kis of 0.3 nM and 12 nM).</p>Formula:C19H29N5O3Purity:99.36%Color and Shape:SolidMolecular weight:375.47Talinolol
CAS:(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.Formula:C20H33N3O3Purity:98.8%Color and Shape:SolidMolecular weight:363.49Ibutamoren Mesylate
CAS:<p>Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.</p>Formula:C28H40N4O8S2Purity:97.98% - ≥98%Color and Shape:SolidMolecular weight:624.77SCH-23390 hydrochloride
CAS:<p>SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).</p>Formula:C17H19Cl2NOPurity:98% - 99.83%Color and Shape:SolidMolecular weight:324.24Clozapine N-Oxide
CAS:View and buy CLOZAPINE N-OXIDE from TargetMol.Clozapine N-oxide is a major metabolite of clozapine also known as DREADDs, technology to modulate synthetic receptors in vivo.Cited in 2 publications.Formula:C18H19ClN4OPurity:98.65% - 99.94%Color and Shape:SolidMolecular weight:342.82SB-334867 free base
CAS:<p>SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.</p>Formula:C17H13N5O2Purity:99.67% - >99.99%Color and Shape:SolidMolecular weight:319.32OXA (17-33) acetate
<p>OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).</p>Formula:C79H125N23O22Purity:98.52%Color and Shape:SolidMolecular weight:1748.98MK-0557
CAS:<p>MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).</p>Formula:C22H19FN4O3Purity:99.88%Color and Shape:SolidMolecular weight:406.41Bradykinin (acetate)
CAS:<p>Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system.</p>Formula:C52H77N15O13Purity:>99.99%Color and Shape:SolidMolecular weight:1120.26Cariprazine hydrochloride
CAS:<p>Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively)</p>Formula:C21H33Cl3N4OPurity:99.78% - >99.99%Color and Shape:SolidMolecular weight:463.872-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
<p>2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.</p>Formula:C38H64F3N11O10Purity:>99.99%Color and Shape:SolidMolecular weight:891.98Ditolylguanidine
CAS:<p>Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).</p>Formula:C15H17N3Purity:98.42%Color and Shape:White To Pinkish Solid PowderMolecular weight:239.32Tetradecyl Phosphonate
CAS:<p>Tetradecyl Phosphonate 是溶血磷脂酸 1 (LPA1)、LPA2 和 LPA3 受体的泛拮抗剂。</p>Formula:C14H31O3PPurity:99.95%Color and Shape:White To Off-White PowderMolecular weight:278.37Midodrine
CAS:<p>Midodrine ((±)-Midodrin), an adrenergic alpha-1 agonist, belongs to the class of medications known as vasopressors.</p>Formula:C12H18N2O4Purity:99.89%Color and Shape:SolidMolecular weight:254.281-[(5-methylisoxazol-3-yl)methyl]piperazine
CAS:<p>1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]- (9CI)) is a P2Y12 inhibitor.</p>Formula:C9H15N3OPurity:95%Color and Shape:SolidMolecular weight:181.23VKGILS-NH2 Acetate
<p>VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.</p>Formula:C30H58N8O9Purity:98.83%Color and Shape:SolidMolecular weight:674.83CGS 21680 Hydrochloride
CAS:<p>CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.</p>Formula:C23H29N7O6·HClPurity:96.74% - 99.53%Color and Shape:SolidMolecular weight:535.98Hydroxyzine dihydrochloride
CAS:<p>Hydroxyzine dihydrochloride treats allergies, pruritus, anxiety; causes drowsiness; also an antiemetic and sedative.</p>Formula:C21H27ClN2O2·2HClPurity:99.46% - 99.79%Color and Shape:Oil PowderMolecular weight:447.83Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:<p>Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-</p>Formula:C24H35ClO9Purity:99.88% - 99.94%Color and Shape:SolidMolecular weight:502.98DORA-22
CAS:<p>DORA-22 is a dual orexin receptor antagonist, improves mild stress-induced insomnia with minimal effect on memory</p>Formula:C23H22F2N4O2Purity:97.67%Color and Shape:SolidMolecular weight:424.44
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