GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,028 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(61 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
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Neurokinin A TFA
CAS:Neurokinin A TFA (NKA TFA) is a neuropeptide within the neurokinin family, serving as the endogenous ligand and agonist for the NK-2 (Neurokinin 2) receptor.Formula:C52H81F3N14O16SPurity:98.704%Color and Shape:SolidMolecular weight:1247.34Cetirizine Impurity C
CAS:Cetirizine Impurity C - a metabolite of hydroxyzine, is a long-acting, oral H1-antihistamine.Formula:C21H25ClN2O3Color and Shape:SolidMolecular weight:388.89HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.Color and Shape:Odour SolidIcatibant
CAS:Icatibant is a selective and specific antagonist of the bradykinin B2 receptor (IC50 and Ki: 1.07 nM and 0.798 nM respectively).Formula:C59H89N19O13SPurity:98%Color and Shape:White SolidMolecular weight:1304.52Kisspeptin-10, human
CAS:Kisspeptin-10, human is an effective vasoconstrictor and inhibitor of angiogenesis.Formula:C63H83N17O14Purity:98%Color and Shape:SolidMolecular weight:1302.462(Leu31,Pro34)-Peptide YY (human)
CAS:(Leu31,Pro34)-Peptide YY (human) is a derivative of Peptide YY, acting as a potent and selective Y1 receptor agonist with a dissociation constant (KD) of 1.0 nMFormula:C195H296N54O56Color and Shape:SolidMolecular weight:4292.75CCK (27-33) (non-sulfated)
CAS:CCK (27-33), a non-sulfated peptide, inhibits [3H]naloxone binding (IC50=4uM) and guinea pig ileum contractions (IC50=17uM), reversed by naloxone.Formula:C45H57N9O10S2Color and Shape:SolidMolecular weight:948.12Pancreatic Polypeptide, bovine
CAS:Agonist at Y4 neuropeptide Y receptors.Formula:C186H287N53O56S2Purity:98%Color and Shape:SolidMolecular weight:4225.78Vapitadine
CAS:Vapitadine is a non-sedative antihistamine compound that relieves itching caused by atopic dermatitis.Formula:C17H20N4OPurity:99.77% - 99.86%Color and Shape:SoildMolecular weight:296.37Urocortin, rat
CAS:Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.Formula:C206H338N62O64Purity:98%Color and Shape:SolidMolecular weight:4707.26Orexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Formula:C152H243N47O44S4Purity:98%Color and Shape:SolidMolecular weight:3561.1[D-Phe2,6, Pro3]-LH-RH
CAS:[D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH).Formula:C59H80N14O13Color and Shape:SolidMolecular weight:1193.35[Tyr1]-Somatostatin-14
CAS:[Tyr1]-Somatostatin-14 could binds to SSTR2.Formula:C82H108N18O20S2Molecular weight:1729.99Oxopurpureine
CAS:Oxopurpureine, classified as an oxoaporphine compound, functions to inhibit plant pathogens.Formula:C21H19NO6Color and Shape:SolidMolecular weight:381.38Elabela(19-32)
CAS:APJ receptor agonist with Ki of 0.93 nM, derived from ELA-32, activates Gαi1, β-arrestin-2, lowers rat heart arterial pressure, effective in vivo.Formula:C75H119N25O17S2Purity:98%Color and Shape:SolidMolecular weight:1707.03Flunarizine
CAS:Flunarizine is an orally administered peripheral vasodilator, a dual blocker of voltage-gated Na+/Ca2+ channels and a D2 dopamine receptor antagonist.Formula:C26H26F2N2Purity:99.9%Color and Shape:SolidMolecular weight:404.50TGR5 agonist 1
Compound 18 (TGR5 agonist 1) is a potent agonist of TGR5, exhibiting an EC50 value of 0.31 µM [1].Formula:C28H48NNaO6SColor and Shape:SolidMolecular weight:549.74IRAK inhibitor 4 trans
IRAK inhibitor 4 targets and blocks IRAK4 activity; refers to its trans molecular configuration.Formula:C33H35F3N6O3Purity:98%Color and Shape:SolidMolecular weight:620.66CB1R agonist 1
CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.Formula:C20H18F3N3O3SColor and Shape:SolidMolecular weight:437.435MRS-1706
CAS:MRS-1706: Ki of 1.39nM for A2B; selective inverse agonist; also affects A2A, A1, A3.Formula:C27H29N5O5Purity:99.00%Color and Shape:SolidMolecular weight:503.55Ref: TM-T16136
1mg34.00€5mg74.00€1mL*10mM (DMSO)84.00€10mg113.00€25mg222.00€50mg356.00€100mg572.00€200mg803.00€
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