GPCR/G-Protein
GPCR/G-Protein inhibitors are compounds that target G-protein coupled receptors (GPCRs) and associated G-proteins, which play critical roles in transmitting signals from the outside to the inside of cells. These inhibitors are essential for studying the signaling pathways mediated by GPCRs, which are involved in numerous physiological processes, including sensory perception, immune response, and neurotransmission. GPCR inhibitors are also important in drug development, as many therapeutic agents target these receptors. At CymitQuimica, we offer a wide range of high-quality GPCR/G-Protein inhibitors to support your research in pharmacology, cell biology, and related fields.
Subcategories of "GPCR/G-Protein"
- 5-HT Receptor(1,025 products)
- Adenosine Receptor(251 products)
- Adrenergic Receptor(3,027 products)
- Bombesin Receptor(35 products)
- Bradykinin Receptor(61 products)
- CXCR(158 products)
- CaSR(34 products)
- Cannabinoid Receptor(218 products)
- Cholecystokinin(1 products)
- Dopamine Receptor(445 products)
- Endothelin Receptor(86 products)
- GNRH Receptor(84 products)
- GPCR19(36 products)
- GRK(33 products)
- GTPase(23 products)
- Glucagon Receptor(195 products)
- Hedgehog/Smoothened(49 products)
- Histamine Receptor(385 products)
- LPA Receptor(21 products)
- Melatonin Receptor(26 products)
- OX Receptor(41 products)
- Opioid Receptor(327 products)
- PAFR(14 products)
- PKA(60 products)
- S1P Receptor(18 products)
- SGLT(31 products)
- Sigma receptor(46 products)
Show 19 more subcategories
Found 6011 products of "GPCR/G-Protein"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BQ-123 TFA
BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.Formula:C33H43F3N6O9Color and Shape:SolidMolecular weight:724.72Yohimbic acid, ethyl ester
CAS:Yohimbic acid, ethyl ester is a biochemical with possible effects on reserpine action.Formula:C22H28N2O3Color and Shape:SolidMolecular weight:368.47Quinazosin hydrochloride
CAS:Quinazosin hydrochloride is an antihypertensive agent.Formula:C17H25Cl2N5O2Color and Shape:SolidMolecular weight:402.32L-703606 oxalate hydrate
L-703606 oxalate hydrate is an effective, selective NK1 receptor antagonist. It is utilized in research related to gastric acid secretion.Color and Shape:Odour SolidL-770644
CAS:L-770644 is an agonist of B3 adrenergic receptor.Formula:C30H37N7O4SColor and Shape:SolidMolecular weight:591.72Leukotriene B4 Ethanolamide
CAS:LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.Formula:C22H37NO4Color and Shape:SolidMolecular weight:379.541IRAK inhibitor 4 trans
IRAK inhibitor 4 targets and blocks IRAK4 activity; refers to its trans molecular configuration.Formula:C33H35F3N6O3Purity:98%Color and Shape:SolidMolecular weight:620.6611-deoxy Prostaglandin E2
CAS:11-deoxy PGE2 is a synthetic PGE2 analog, a potent bronchoconstrictor, 5-30x stronger than PGF2α on human respiratory muscles.Formula:C20H32O4Color and Shape:SolidMolecular weight:336.47Ivabradine-d3 hydrochloride
CAS:Ivabradine HCl: novel If blocker, IC50 2.9 μM, slows heart rate; D3 version is deuterium labeled.Formula:C27H37ClN2O5Purity:98%Color and Shape:SolidMolecular weight:508.0713,14-dihydro-15-keto Prostaglandin F1α
CAS:13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach.Formula:C20H36O5Color and Shape:SolidMolecular weight:356.5FSLLRY-NH2
CAS:PAR2 antagonist; counters taxol effects, PKC in mice; inhibits ERK, collagen in fibroblasts; lessens dermatophyte itch in mice.Formula:C39H60N10O8Purity:98%Color and Shape:SolidMolecular weight:796.97TGR5 agonist 2
TGR5 agonist 2 (compound 19) serves as a highly potent agonist of TGR5, demonstrating an EC50 value of 0.27 µM [1].Formula:C29H50NNaO6SColor and Shape:SolidMolecular weight:563.77Dipentylone hydrochloride
CAS:Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.Formula:C14H20ClNO3Purity:99.94%Color and Shape:SolidMolecular weight:285.77Maceneolignan H
CAS:Maceneolignan H, a neolignane from Myristica fragrans, selectively blocks CCR3 (EC50=1.4μM) with allergy research potential.Formula:C24H30O7Color and Shape:SolidMolecular weight:430.49VU0453379 hydrochloride
VU0453379 hydrochloride: selective CNS-penetrant GLP-1R PAM, EC50 1.3 μM.Formula:C26H35ClN4O2Color and Shape:SolidMolecular weight:471.03α-CGRP (mouse, rat) (TFA)
α-CGRP (mouse, rat) TFA is a neuropeptide (calcitonin gene-related peptide) predominantly found at neuromuscular junctions and acts as a potent vasodilator. This compound is useful in research concerning cardiovascular, pro-inflammatory, migraine, and metabolic processes.Color and Shape:Odour SolidAntisauvagine-30
CAS:CRF2 receptor antagonist; Kd 1.4 nM (mCRF2β), 153.6 nM (rCRF1). Blocks sauvagine-induced cAMP in cells & stress-related responses in mice.Formula:C161H274N48O46SPurity:98%Color and Shape:SolidMolecular weight:3650.29GI-560192
CAS:GI-560192 (RL-0070933), a potent smo modulator, EC50: 0.02µM; affects smoothened in cilia via hedgehog signaling.Formula:C20H16N2O2Purity:99.53%Color and Shape:SoildMolecular weight:316.35Ref: TM-T64351
1mg85.00€5mg170.00€1mL*10mM (DMSO)170.00€10mg250.00€25mg371.00€50mg522.00€100mg712.00€200mg954.00€ACTH (1-17)
CAS:ACTH (1-17), a potent MC1 receptor agonist with a Ki of 0.21 nM, is a variant of corticotropin from the pituitary gland.Formula:C95H145N29O23SPurity:98%Color and Shape:SolidMolecular weight:2093.41mPGES-1/sEH-IN-1
mPGES-1/sEH-IN-1 (compound 1f) is an sEH inhibitor with an IC50 value of 5 μM. It also exhibits antitumor activity by inhibiting mPGES-1, with an IC50 value of 25 µM.Formula:C20H16F3N3O2Color and Shape:SolidMolecular weight:387.355
