Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(90 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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Epothilone B
CAS:Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum.Formula:C27H41NO6SPurity:99.79% - 99.84%Color and Shape:White PowderMolecular weight:507.68Ref: TM-T6075
1mg34.00€2mg48.00€5mg63.00€10mg94.00€25mg203.00€50mg369.00€100mg537.00€1mL*10mM (DMSO)70.00€Pitavastatin calcium
CAS:Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.Formula:C50H46CaF2N2O8Purity:98.89% - >99.99%Color and Shape:White To Off-White PowderMolecular weight:880.98RIPGBM
CAS:RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).Formula:C26H21FN2O3Purity:99.45%Color and Shape:SolidMolecular weight:428.45Ref: TM-T16754
2mg35.00€5mg54.00€10mg93.00€25mg177.00€50mg318.00€100mg530.00€200mg677.00€1mL*10mM (DMSO)60.00€Dapivirine
CAS:Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Formula:C20H19N5Purity:98% - 99.77%Color and Shape:SolidMolecular weight:329.4Melatonin
CAS:Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.Formula:C13H16N2O2Purity:98% - 99.89%Color and Shape:Pale Yellow Leaflets From Benzene SolidMolecular weight:232.28Chrysosplenol D
CAS:Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.Formula:C18H16O8Purity:97.87% - 99.98%Color and Shape:SolidMolecular weight:360.31R547
CAS:R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.Formula:C18H21F2N5O4SPurity:90% - 99.64%Color and Shape:SolidMolecular weight:441.45Ref: TM-T6312
1mg48.00€5mg96.00€10mg140.00€25mg254.00€50mg487.00€100mg700.00€200mg973.00€1mL*10mM (DMSO)114.00€Ethoxysanguinarine
CAS:Ethoxysanguinarine inhibits HuAChE and HuBuChE with IC50s of 0.83 and 4.20 μM, respectively.Formula:C22H19NO5Purity:99.24% - 99.48%Color and Shape:SolidMolecular weight:377.39Ref: TM-TN1305
1mg54.00€5mg120.00€10mg192.00€25mg324.00€50mg480.00€100mg683.00€1mL*10mM (DMSO)146.00€Avadomide
CAS:Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity.Formula:C14H14N4O3Purity:99.56%Color and Shape:SolidMolecular weight:286.29PHA-793887
CAS:PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.Formula:C19H31N5O2Purity:98.02% - >99.99%Color and Shape:SolidMolecular weight:361.48Ref: TM-T2113
2mg34.00€5mg49.00€10mg75.00€25mg114.00€50mg185.00€100mg298.00€200mg444.00€1mL*10mM (DMSO)50.00€Sincalide
CAS:Sincalide (CCK-8) is an injectable drug used to diagnose gallbladder and pancreas disorders; it's a cholecystokinin fragment.Formula:C49H62N10O16S3Purity:98.32%Color and Shape:SolidMolecular weight:1143.27Hematoporphyrin dihydrochloride
CAS:Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride) is a substrate for affinity chromatography of heme-binding proteins.Formula:C34H40Cl2N4O6Purity:97.79%Color and Shape:SolidMolecular weight:671.61PluriSIn 1
CAS:PluriSIn 1 (NSC 14613) blocks SCD1, key in oleic acid creation, showing lipid metabolism's role in hPSCs.Formula:C12H11N3OPurity:99.19% - 99.63%Color and Shape:SolidMolecular weight:213.24Ref: TM-T1869
5mg37.00€10mg57.00€25mg92.00€50mg119.00€100mg170.00€200mg240.00€500mg404.00€1mL*10mM (DMSO)40.00€BTSA1
CAS:BTSA1: High-affinity BAX activator inducing conformational changes for apoptosis.Formula:C21H14N6OS2Purity:99.60% - 99.71%Color and Shape:SolidMolecular weight:430.51Ref: TM-T5104
2mg46.00€5mg70.00€10mg119.00€25mg188.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)77.00€Cambinol
CAS:Cambinol is a SIRT1/2 inhibitor (IC50: 56/59 μM), non-competitive with NAD, weak on SIRT5, and prompts apoptosis in lymphoma cells.Formula:C21H16N2O2SPurity:98.02% - 99.83%Color and Shape:SolidMolecular weight:360.43Ref: TM-T4019
1mg38.00€2mg50.00€5mg80.00€10mg117.00€25mg207.00€50mg333.00€100mg495.00€500mg1,071.00€1mL*10mM (DMSO)63.00€L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11Jaceosidin
CAS:Jaceosidin: anti-oxidant, anti-inflammatory, anti-cancer, immunosuppressive; affects CYP1A2/UGT1A1/UGT1A7 metabolism.Formula:C17H14O7Purity:98.23% - 99.28%Color and Shape:SolidMolecular weight:330.29Naphthazarin
CAS:Naphthazarin triggers apoptosis, has anti-tumor effects via oxidative stress, mitochondrial AIF, microtubule depolymerization, and p53/p21 activation.Formula:C10H6O4Purity:98.12% - 99.87%Color and Shape:Dark Purple To Brown-Black PowderMolecular weight:190.15Sophoraflavanone G
CAS:Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-relatedFormula:C25H28O6Purity:97.09% - 99.77%Color and Shape:SolidMolecular weight:424.49PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Ref: TM-T6954
5mg49.00€10mg70.00€25mg133.00€50mg195.00€100mg349.00€200mg518.00€500mg830.00€1mL*10mM (DMSO)54.00€GSK2656157
CAS:GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.Formula:C23H21FN6OPurity:98.59% - >99.99%Color and Shape:SolidMolecular weight:416.45Ref: TM-T2654
2mg34.00€5mg52.00€10mg77.00€25mg135.00€50mg245.00€100mg442.00€200mg598.00€1mL*10mM (DMSO)52.00€KRAS inhibitor-9
CAS:KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formula:C13H9ClN2S2Purity:99.66%Color and Shape:SolidMolecular weight:292.81Ref: TM-T8756
1mg57.00€2mg81.00€5mg113.00€10mg178.00€25mg334.00€50mg485.00€100mg622.00€1mL*10mM (DMSO)136.00€AZD-8055
CAS:AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.Formula:C25H31N5O4Purity:98% - 99.69%Color and Shape:SolidMolecular weight:465.54Aristolactam I
CAS:Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Formula:C17H11NO4Purity:98.98% - 99.96%Color and Shape:SolidMolecular weight:293.27Ref: TM-T3S1227
1mg57.00€5mg133.00€10mg205.00€25mg350.00€50mg515.00€100mg735.00€1mL*10mM (DMSO)172.00€Nimustine Hydrochloride
CAS:Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.Formula:C9H14Cl2N6O2Purity:98.80%Color and Shape:SolidMolecular weight:309.15Ref: TM-T5017
2mgTo inquire5mg52.00€10mg74.00€25mg97.00€50mg160.00€100mg283.00€200mgTo inquire1mL*10mM (DMSO)52.00€Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:SolidMolecular weight:537.96Ref: TM-T5164
1mg42.00€2mg52.00€5mg65.00€10mg92.00€25mg160.00€50mg235.00€100mg330.00€200mg538.00€500mg860.00€Malachite green oxalate
CAS:Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.Formula:C23H25N2·C2HO4C2H2O4Color and Shape:Dark Green Crystals With A Metallic LusterMolecular weight:463.51HYPOCRELLIN B
CAS:HYPOCRELLIN B, from Hypocrella bambusae, breaks DNA, triggers apoptosis in ovarian cells, and stops Staphylococcus growth via ROS.Formula:C30H24O9Purity:98% - 98.87%Color and Shape:SolidMolecular weight:528.51Madecassoside
CAS:Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activitiesFormula:C48H78O20Purity:99.46% - 99.85%Color and Shape:White PowderMolecular weight:975.12Ref: TM-T2813
10mg49.00€25mg84.00€50mg120.00€100mg178.00€200mg289.00€500mg485.00€1mL*10mM (DMSO)49.00€BMS-1
CAS:BMS-1 is a PD-1/PD-L1 inhibitor and immunomodulator; it targets the CD274 gene product, PD-L1, linked to tumor evasion and higher mortality.
Formula:C29H33NO5Purity:99.40% - 99.81%Color and Shape:SolidMolecular weight:475.58Baicalein monohydrate
CAS:Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.Formula:C15H12O6Color and Shape:SolidMolecular weight:288.25Amantadine
CAS:Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.Formula:C10H17NPurity:99.73% - 99.94%Color and Shape:Hexakistetrahedral Crystals By Sublimation SolidMolecular weight:151.25(S)-CPI203
CAS:CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurity:99.01% - 99.92%Color and Shape:SolidMolecular weight:399.9Ref: TM-T6026
2mg34.00€5mg55.00€10mg89.00€25mg170.00€50mg269.00€100mg424.00€200mg593.00€1mL*10mM (DMSO)58.00€Scriptaid
CAS:Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.Formula:C18H18N2O4Purity:96.74% - 99.45%Color and Shape:SolidMolecular weight:326.35Ref: TM-T6980
5mg67.00€10mg92.00€25mg193.00€50mg358.00€100mg537.00€500mg1,134.00€1mL*10mM (DMSO)74.00€Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formula:C19H19FO4Purity:97.58% - 98%Color and Shape:SolidMolecular weight:330.35Sodium taurodeoxycholate hydrate
CAS:Sodium taurodeoxycholate hydrate (Taurodeoxycholic acid sodium salt monohydrate) has been used in a study to assess the effect of submicellar concentrations ofFormula:C26H44NO6S·Na·H2OPurity:99.78%Color and Shape:SolidMolecular weight:539.70TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C23H20N6OPurity:99.71%Color and Shape:SolidMolecular weight:396.44Ref: TM-T16996
1mg93.00€2mg117.00€5mg178.00€10mg295.00€25mg595.00€50mg795.00€100mg1,071.00€200mg1,468.00€1mL*10mM (DMSO)203.00€4E1rcat
CAS:4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.Formula:C28H18N2O6Purity:99.47%Color and Shape:SolidMolecular weight:478.454-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurity:97.18%Color and Shape:SolidMolecular weight:313.42Ref: TM-T8794
2mg34.00€5mg52.00€10mg86.00€25mg156.00€50mg245.00€100mg403.00€200mg568.00€1mL*10mM (DMSO)58.00€Isatin
CAS:Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.Formula:C8H5NO2Purity:98.92%Color and Shape:Yellow To Reddish Crystalline SolidMolecular weight:147.13UNC1215
CAS:UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).Formula:C32H43N5O2Purity:98% - 99.04%Color and Shape:SolidMolecular weight:529.72AES-350
CAS:AES-350, an HDAC6 inhibitor (IC50: 0.0244 μM), also targets HDAC-3, -8, -11, induces AML cell apoptosis, and aids AML research.Formula:C18H20N2O3Purity:98.82%Color and Shape:SolidMolecular weight:312.36N-Formyl-Met-Leu-Phe
CAS:N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).Formula:C21H31N3O5SPurity:98.69% - 98.69%Color and Shape:SolidMolecular weight:437.55Rotundic acid
CAS:Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.Formula:C30H48O5Purity:96.91% - 99.97%Color and Shape:SolidMolecular weight:488.70Ref: TM-T5S0506
2mg34.00€5mg49.00€10mg75.00€25mg137.00€50mg215.00€100mg319.00€200mg474.00€1mL*10mM (DMSO)49.00€Apremilast
CAS:Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.Formula:C22H24N2O7SPurity:98.13% - 99.95%Color and Shape:SolidMolecular weight:460.50Polyporenic acid C
CAS:Polyporenic acid C shows inhibitory activity against human collagenase.Formula:C31H46O4Purity:96.84% - 99.90%Color and Shape:SolidMolecular weight:482.69Ref: TM-TN1153
1mg66.00€5mg177.00€10mg304.00€25mg509.00€50mg710.00€100mg982.00€1mL*10mM (DMSO)212.00€IACS-010759
CAS:IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.Formula:C25H25F3N6O4SPurity:99.54% - 99.73%Color and Shape:SolidMolecular weight:562.56Ref: TM-T5337
1mg49.00€2mg70.00€5mg107.00€10mg165.00€25mg334.00€50mg485.00€100mg710.00€200mg964.00€1mL*10mM (DMSO)141.00€MDK83190
CAS:MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .Formula:C15H9Cl2NO2Purity:97.40% - 98%Color and Shape:Orange SolidMolecular weight:306.14Thapsigargin
CAS:Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer.Formula:C34H50O12Purity:99.07% - 99.3%Color and Shape:Colourless FilmMolecular weight:650.75PS-1145
CAS:PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.Formula:C17H11ClN4OPurity:98.81% - >99.99%Color and Shape:SolidMolecular weight:322.75Ref: TM-T3094
1mg39.00€2mg52.00€5mg87.00€10mg120.00€25mg245.00€50mg394.00€100mg620.00€200mg875.00€1mL*10mM (DMSO)96.00€Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purity:98.75% - 99.57%Color and Shape:SolidMolecular weight:199.25Ref: TM-T4414
5mg70.00€10mg100.00€25mg195.00€50mg349.00€100mg618.00€500mg1,251.00€1mL*10mM (DMSO)77.00€Quinidine sulfate dihydrate
CAS:Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitorFormula:C40H54N4O10SPurity:99.85%Color and Shape:White To Light Yellow Crystal PowdeMolecular weight:782.9Ref: TM-T8125
5mg42.00€10mg52.00€25mg73.00€50mg94.00€100mg142.00€200mg207.00€500mg348.00€1mL*10mM (DMSO)62.00€Prexasertib Mesylate Hydrate
CAS:Prexasertib Mesylate Hydrate is a potent CHK1 inhibitor (IC50<1nM), also inhibits CHK2, RSK1, induces DNA breaks, apoptosis, and has anti-tumor effects.Formula:C19H25N7O6SColor and Shape:SolidMolecular weight:479.51(20S)-Protopanaxatriol
CAS:(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoidFormula:C30H52O4Purity:95% - 99%Color and Shape:SolidMolecular weight:476.73Ref: TM-T2810
2mg34.00€5mg50.00€10mg66.00€25mg114.00€50mg178.00€100mg295.00€200mg442.00€1mL*10mM (DMSO)55.00€Mycophenolate Mofetil
CAS:Mycophenolate Mofetil (TM-MMF), is an immunosuppressive agent, 2-morpholinoethyl ester of MPA, and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).Formula:C23H31NO7Purity:98.27% - 99.85%Color and Shape:White To Off-White Crystalline PowderMolecular weight:433.49PRLX-93936
CAS:PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.Formula:C21H24N4O2Color and Shape:SolidMolecular weight:364.44TCS7010
CAS:TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.Formula:C31H31ClFN7O2Purity:98.49% - 99.62%Color and Shape:SolidMolecular weight:588.07Rosmarinic acid
CAS:Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities.Formula:C18H16O8Purity:98.88% - 99.73%Color and Shape:Brown Fine PowderMolecular weight:360.31Millepachine
CAS:Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.Formula:C22H22O4Purity:99.73%Color and Shape:SolidMolecular weight:350.41Ref: TM-T38815
1mg52.00€5mg110.00€10mg147.00€25mg245.00€50mg358.00€100mg537.00€200mg710.00€1mL*10mM (DMSO)127.00€Vanillyl Alcohol
CAS:Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant and anti-nociceptive activities.Formula:C8H10O3Purity:97.02% - 98.42%Color and Shape:Crystalline White To Off-White PowderMolecular weight:154.16NVP 231
CAS:NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.
Formula:C25H25N3O2SPurity:99.16% - ≥95%Color and Shape:SolidMolecular weight:431.55DC260126
CAS:DC260126 is a small-molecule antagonist of FFA1 (GPR40)Formula:C16H18FNO2SPurity:99.77%Color and Shape:SolidMolecular weight:307.38Rimiducid
CAS:Rimiducid, a tacrolimus analogue, dimerizes FKBP domains to activate Caspase 9 and induce apoptosis; binds FKBP12 weakly.Formula:C78H98N4O20Purity:99.54%Color and Shape:SolidMolecular weight:1411.63Ref: TM-T14298
1mg129.00€2mg177.00€5mg285.00€10mg420.00€25mg692.00€50mg973.00€100mg1,305.00€500mg2,602.00€Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purity:99.25%Color and Shape:Yellowish SolidMolecular weight:379.88Ref: TM-T6568
5mg44.00€10mg66.00€25mg119.00€50mg177.00€100mg264.00€200mg394.00€500mg623.00€1mL*10mM (DMSO)48.00€SCR130
CAS:SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。Formula:C19H13Cl2N3O2SPurity:98.9%Color and Shape:SolidMolecular weight:418.3PF-3758309 dihydrochloride
PF-3758309 dihydrochloride is a potent PAK4 inhibitor (Kd = 2.7 nM, Ki = 18.7 nM), oral, ATP-competitive; blocks cell growth, induces apoptosis.Formula:C25H32Cl2N8OSColor and Shape:SolidMolecular weight:563.55Lupiwighteone
CAS:Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Formula:C20H18O5Purity:98.92%Color and Shape:SolidMolecular weight:338.35TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Formula:C21H17ClN2O6Purity:97.62% - 99.09%Color and Shape:SolidMolecular weight:428.82BTdCPU
CAS:BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.Formula:C13H8Cl2N4OSPurity:98.94% - 99.59%Color and Shape:SolidMolecular weight:339.2Ref: TM-T7150
1mg138.00€5mg286.00€10mg442.00€25mg713.00€50mg1,018.00€100mg1,369.00€500mg2,673.00€1mL*10mM (DMSO)236.00€AMG-337
CAS:AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 inhibits MET kinase activity (IC50: < 5 nM).Formula:C23H22FN7O3Purity:99.26% - 99.9%Color and Shape:SolidMolecular weight:463.46Ref: TM-T3209
1mg38.00€2mg50.00€5mg80.00€10mg117.00€25mg187.00€50mg333.00€100mg495.00€200mg710.00€1mL*10mM (DMSO)81.00€PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formula:C17H13BrN4OPurity:99.13% - 99.83%Color and Shape:SolidMolecular weight:369.22Ref: TM-T6932
1mg37.00€2mg50.00€5mg63.00€10mg94.00€25mg146.00€50mg210.00€100mg294.00€1mL*10mM (DMSO)52.00€SEC inhibitor KL-1
CAS:KL-1, a potent SEC inhibitor, disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM, selectively targeting the SEC.Formula:C18H16ClNO4Purity:97.42%Color and Shape:SolidMolecular weight:345.78Ref: TM-T16867
1mg40.00€2mg55.00€5mg90.00€10mg131.00€25mg215.00€50mg325.00€100mg464.00€200mg645.00€1mL*10mM (DMSO)90.00€WYE-354
CAS:WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Formula:C24H29N7O5Purity:97.86% - 99.61%Color and Shape:SolidMolecular weight:495.53McMMAF
CAS:McMMAF is a protective group-conjugated MMAF.Formula:C49H76N6O11Purity:99.65% - >99.99%Color and Shape:SolidMolecular weight:925.16TASIN-1
CAS:TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).Formula:C18H28N2O3SPurity:99.86%Color and Shape:SolidMolecular weight:352.49Ref: TM-T22632
1mg37.00€5mg79.00€10mg124.00€25mg255.00€50mg409.00€100mg605.00€500mg1,288.00€1mL*10mM (DMSO)87.00€Iproniazid
CAS:Iproniazid is an irreversible monoamine oxidase inhibitor. It is used as an antidepressive agent.Formula:C9H13N3OPurity:98%Color and Shape:SolidMolecular weight:179.22Glafenine Hydrochloride
CAS:Glafenine Hydrochloride is an anti-inflammatory agent.Formula:C19H17ClN2O4·HClPurity:98.89%Color and Shape:SolidMolecular weight:409.26TASIN-1 Hydrochloride
CAS:TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncatedFormula:C18H29ClN2O3SPurity:99.94%Color and Shape:SolidMolecular weight:388.95Ref: TM-T24855
1mg73.00€5mg136.00€10mg187.00€25mg318.00€50mg452.00€100mg627.00€200mg845.00€1mL*10mM (DMSO)142.00€Romidepsin
CAS:Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.Formula:C24H36N4O6S2Purity:99.4% - 99.94%Color and Shape:SolidMolecular weight:540.7PX-12
CAS:PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.Formula:C7H12N2S2Purity:98% - 99.21%Color and Shape:SolidMolecular weight:188.31L524-0366
CAS:L524-0366 ([1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone) is a TWEAK-Fn14 signaling cascade inhibitor.
Formula:C13H13ClN4OSPurity:98.6% - 99.13%Color and Shape:SolidMolecular weight:308.79Piperazine Erastin
CAS:Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.Formula:C35H41ClN6O4Purity:99.52%Color and Shape:SolidMolecular weight:645.19Ref: TM-T16540
1mg92.00€5mg165.00€10mg268.00€25mg537.00€50mg879.00€100mg1,161.00€200mg1,594.00€500mg2,367.00€1mL*10mM (DMSO)227.00€WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formula:C16H14BrN3O3Purity:98% - 99.67%Color and Shape:SolidMolecular weight:376.2S63845
CAS:S63845 is a selective myeloid leukemia 1（MCL1) inhibitor that binds to human MCL1 with a Kd of 0.19 nM.Cost-effective and quality-assured.Formula:C39H37ClF4N6O6SPurity:97.7% - ≥98%Color and Shape:SolidMolecular weight:829.26Mdivi-1
CAS:Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formula:C15H10Cl2N2O2SPurity:96.57% - 99.23%Color and Shape:SolidMolecular weight:353.22Ref: TM-T1907
5mg44.00€10mg52.00€25mg95.00€50mg144.00€100mg215.00€200mg319.00€500mg530.00€1mL*10mM (DMSO)48.00€Quinidine
CAS:Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formula:C20H24N2O2Purity:97.03% - 99.99%Color and Shape:Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Molecular weight:324.42PYR-41
CAS:PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.Formula:C17H13N3O7Purity:98.25%Color and Shape:SolidMolecular weight:371.3Ref: TM-T6629
2mg37.00€5mg54.00€10mg82.00€25mg154.00€50mg294.00€100mg447.00€200mg618.00€500mg973.00€1mL*10mM (DMSO)60.00€Lupeol
CAS:Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.Formula:C30H50OPurity:98% - 99.96%Color and Shape:Needles From Alcohol Acetone White PowderMolecular weight:426.72Purvalanol A
CAS:Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.Formula:C19H25ClN6OPurity:98.13% - 99.68%Color and Shape:PowderMolecular weight:388.89Meisoindigo
CAS:Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).Formula:C17H12N2O2Purity:98.03% - 98.19%Color and Shape:SolidMolecular weight:276.29Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Formula:C14H12O2Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:212.24M50054
CAS:Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.Formula:C13H16O4Purity:97.8%Color and Shape:SolidMolecular weight:236.26BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56BI 2536
CAS:BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.Formula:C28H39N7O3Purity:98% - 99.88%Color and Shape:SolidMolecular weight:521.65Ref: TM-T6173
1mg43.00€2mg56.00€5mg93.00€10mg98.00€25mg117.00€50mg187.00€100mg333.00€500mg797.00€1mL*10mM (DMSO)92.00€Copanlisib
CAS:Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.Formula:C23H28N8O4Purity:99% - 99.88%Color and Shape:SolidMolecular weight:480.52Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formula:C20H18O11Purity:97.02% - 99.94%Color and Shape:White PowderMolecular weight:434.35Ref: TM-T6S0117
1mg55.00€5mg92.00€10mg152.00€25mg268.00€50mg395.00€100mg583.00€200mg832.00€1mL*10mM (DMSO)105.00€PD146176
CAS:PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.Formula:C15H11NSPurity:98.00%Color and Shape:SolidMolecular weight:237.32Terrestrosin D
CAS:Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.
Formula:C50H80O23Purity:99.92% - 99.96%Color and Shape:SolidMolecular weight:1049.16Ganetespib
CAS:Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.Formula:C20H20N4O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:364.4Ref: TM-T2309
5mg63.00€10mg93.00€25mg126.00€50mg158.00€100mg236.00€200mg401.00€500mg665.00€1mL*10mM (DMSO)71.00€Aminopurvalanol A
CAS:Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1Formula:C19H26ClN7OPurity:99.73%Color and Shape:SolidMolecular weight:403.91Ref: TM-T22260
2mg39.00€5mg60.00€10mg92.00€25mg173.00€50mg269.00€100mg389.00€200mg555.00€1mL*10mM (DMSO)62.00€
