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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5592 products of "Apoptosis"

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  • Iberdomide

    CAS:
    <p>Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).</p>
    Formula:C25H27N3O5
    Purity:97.01%
    Color and Shape:Solid
    Molecular weight:449.5
  • Kynurenic acid sodium

    CAS:
    <p>Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.</p>
    Formula:C10H6NNaO3
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:211.15
  • Pembrolizumab

    CAS:
    <p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>
    Purity:95% - 99.70%
    Color and Shape:Liquid
    Molecular weight:149 kDa
  • Torin 2

    CAS:
    <p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>
    Formula:C24H15F3N4O
    Purity:98.31% - 99.32%
    Color and Shape:Solid
    Molecular weight:432.4
  • OTS514 hydrochloride

    CAS:
    <p>OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).</p>
    Formula:C21H20N2O2S·HCl
    Purity:99.67% - 99.84%
    Color and Shape:Solid
    Molecular weight:400.92
  • Alginic acid

    CAS:
    <p>Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.</p>
    Formula:C14H22O13
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:398.317
  • Inauhzin

    CAS:
    <p>Inauhzin (INZ) reactivates p53, inhibits SIRT1, induces Y cell apoptosis without genotoxic stress (IC50=3 uM in A549).</p>
    Formula:C25H19N5OS2
    Purity:98% - 99.36%
    Color and Shape:Solid
    Molecular weight:469.58
  • EGFR-IN-12

    CAS:
    <p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>
    Formula:C21H18F3N5O
    Purity:98.3% - 99.76%
    Color and Shape:Solid
    Molecular weight:413.4
  • DRB

    CAS:
    <p>DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)</p>
    Formula:C12H12Cl2N2O4
    Purity:99.46% - 99.83%
    Color and Shape:White To Off-White Crystalline Solid
    Molecular weight:319.14
  • Volasertib

    CAS:
    <p>Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis.</p>
    Formula:C34H50N8O3
    Purity:98% - 99.72%
    Color and Shape:Solid
    Molecular weight:618.81
  • G5-7

    CAS:
    <p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>
    Formula:C22H19F2NO3
    Purity:97.3%
    Color and Shape:Solid
    Molecular weight:383.39
  • Pioglitazone potassium

    CAS:
    <p>Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.</p>
    Formula:C19H19KN2O3S
    Color and Shape:Solid
    Molecular weight:394.53
  • Fedratinib hydrochloride hydrate

    CAS:
    <p>Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.</p>
    Formula:C27H40Cl2N6O4S
    Purity:98.96% - 99.87%
    Color and Shape:Solid
    Molecular weight:615.61
  • Epothilone A

    CAS:
    <p>Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.</p>
    Formula:C26H39NO6S
    Purity:99.89% - 99.92%
    Color and Shape:Solid
    Molecular weight:493.66
  • trans-Chalcone

    CAS:
    <p>trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as</p>
    Formula:C15H12O
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:208.26
  • Ganetespib

    CAS:
    <p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>
    Formula:C20H20N4O3
    Purity:98% - 99.95%
    Color and Shape:Solid
    Molecular weight:364.4
  • 4-Methyldaphnetin

    CAS:
    <p>4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.</p>
    Formula:C10H8O4
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:192.17
  • Polyphyllin I

    CAS:
    <p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>
    Formula:C44H70O16
    Purity:98% - 99.5%
    Color and Shape:Solid
    Molecular weight:855.02
  • FOXO4-DRI acetate


    <p>FOXO4-DRI acetate is a bioactive chemical.</p>
    Formula:C36H64N14O14S
    Purity:99.10%
    Color and Shape:Solid
    Molecular weight:5358.06
  • MRS 2578

    CAS:
    <p>MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.</p>
    Formula:C20H20N6S4
    Purity:97.58% - 99.73%
    Color and Shape:White Solid
    Molecular weight:472.67
  • BAY 61-3606 dihydrochloride

    CAS:
    <p>BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).</p>
    Formula:C20H18N6O3·2HCl
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:463.32
  • WM-3835

    CAS:
    <p>WM-3835, a specific KAT7 inhibitor, potently halts OS cell growth, migration, and induces apoptosis.</p>
    Formula:C20H17FN2O4S
    Purity:97.78% - 99.36%
    Color and Shape:Solid
    Molecular weight:400.42
  • Pitavastatin calcium

    CAS:
    <p>Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.</p>
    Formula:C50H46CaF2N2O8
    Purity:98.89% - >99.99%
    Color and Shape:White To Off-White Powder
    Molecular weight:880.98
  • Atezolizumab

    CAS:
    <p>Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.</p>
    Purity:95.10% - 99.3% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:145 kDa
  • API-1

    CAS:
    <p>API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .</p>
    Formula:C13H15N5O6
    Purity:97.15%
    Color and Shape:Solid
    Molecular weight:337.29
  • SP-141

    CAS:
    <p>SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.</p>
    Formula:C22H16N2O
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:324.38
  • Periplocin

    CAS:
    <p>Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.</p>
    Formula:C36H56O13
    Purity:99.66% - 99.74%
    Color and Shape:Solid
    Molecular weight:696.82
  • CAY10505

    CAS:
    <p>CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).</p>
    Formula:C14H8FNO3S
    Purity:99.69% - 99.74%
    Color and Shape:Solid
    Molecular weight:289.28
  • Brevilin A

    CAS:
    <p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>
    Formula:C20H26O5
    Purity:99.97% - >99.99%
    Color and Shape:Solid
    Molecular weight:346.42
  • Methotrexate disodium

    CAS:
    <p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>
    Formula:C20H20N8Na2O5
    Purity:99.77% - 99.96%
    Color and Shape:Solid
    Molecular weight:498.4
  • VK3-OCH3

    CAS:
    <p>VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.</p>
    Formula:C14H14O3S
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:262.32
  • Acacetin

    CAS:
    <p>Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant</p>
    Formula:C16H12O5
    Purity:96.26% - ≥95%
    Color and Shape:Pale-Yellow Needles
    Molecular weight:284.26
  • RIPGBM

    CAS:
    <p>RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).</p>
    Formula:C26H21FN2O3
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:428.45
  • AC1NS4RE

    CAS:
    <p>It is a tyrosine kinase inhibitor.</p>
    Formula:C15H13ClN2O
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:272.73
  • G-749

    CAS:
    <p>G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.</p>
    Formula:C25H25BrN6O2
    Purity:98.32% - 99.60%
    Color and Shape:Solid
    Molecular weight:521.41
  • Juglanin

    CAS:
    <p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>
    Formula:C20H18O10
    Purity:98.8% - 99.33%
    Color and Shape:Solid
    Molecular weight:418.35
  • L-Glutamic acid

    CAS:
    <p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>
    Formula:C5H9NO4
    Purity:99.14% - 99.55%
    Color and Shape:White Solid Crystalline
    Molecular weight:147.13
  • Triptolide

    CAS:
    <p>Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.</p>
    Formula:C20H24O6
    Purity:97.19% - 99.97%
    Color and Shape:White To Off-White Solid
    Molecular weight:360.4
  • AT7519 Hydrochloride

    CAS:
    <p>AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.</p>
    Formula:C16H18Cl3N5O2
    Purity:99.66% - 99.9%
    Color and Shape:Solid
    Molecular weight:418.71
  • Scoulerine

    CAS:
    <p>Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).</p>
    Formula:C19H21NO4
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:327.37
  • Mitoxantrone

    CAS:
    <p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>
    Formula:C22H28N4O6
    Purity:96.29% - 98.74%
    Color and Shape:Blue Powder
    Molecular weight:444.48
  • HJC0152 hydrochloride

    CAS:
    <p>HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.</p>
    Formula:C15H14Cl3N3O4
    Purity:99.01% - 99.06%
    Color and Shape:Solid
    Molecular weight:406.64
  • Pectolinarin

    CAS:
    <p>Pectolinarin is a Cirsium isolate with anti-inflammatory activity.</p>
    Formula:C29H34O15
    Purity:98% - 99.79%
    Color and Shape:Solid
    Molecular weight:622.57
  • 2,5-dimethyl Celecoxib

    CAS:
    <p>2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.</p>
    Formula:C18H16F3N3O2S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:395.4
  • Leachianone A

    CAS:
    <p>Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.</p>
    Formula:C26H30O6
    Purity:98.53% - 99.79%
    Color and Shape:Solid
    Molecular weight:438.51
  • Rasagiline Mesylate

    CAS:
    <p>Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.</p>
    Formula:C13H17NO3S
    Purity:99.33%
    Color and Shape:White Powder
    Molecular weight:267.34
  • Lycorine

    CAS:
    <p>Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.</p>
    Formula:C16H17NO4
    Purity:98.60% - 99.95%
    Color and Shape:Solid
    Molecular weight:287.31
  • Nutlin-3b

    CAS:
    <p>Nutlin-3b, a less potent (+)-enantiomer of Nutlin-3, inhibits p53/MDM2 at IC50: 13.6 μM, 150x weaker than Nutlin-3a.</p>
    Formula:C30H30Cl2N4O4
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:581.49
  • 2BAct

    CAS:
    <p>2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response</p>
    Formula:C19H16ClF3N4O3
    Purity:97.97% - 99.04%
    Color and Shape:Solid
    Molecular weight:440.8
  • Masitinib

    CAS:
    <p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>
    Formula:C28H30N6OS
    Purity:97.56% - >99.99%
    Color and Shape:Solid
    Molecular weight:498.64
  • Linalool

    CAS:
    <p>Linalool, in essential oils, offers antinociceptive, antimicrobial, and anti-inflammatory effects, protects the liver, and boosts plant defense.</p>
    Formula:C10H18O
    Purity:98.22%
    Color and Shape:Colorless Liquid Drypowder Liquid Othersolid Liquid
    Molecular weight:154.25
  • Pexidartinib

    CAS:
    <p>Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential</p>
    Formula:C20H15ClF3N5
    Purity:98.34% - 99.45%
    Color and Shape:Solid
    Molecular weight:417.81
  • Topotecan

    CAS:
    <p>Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.</p>
    Formula:C23H23N3O5
    Purity:96.14% - 98.23%
    Color and Shape:Light Yellow Needle Crystal Or Crystalline Powder
    Molecular weight:421.45
  • Isosilybin A

    CAS:
    <p>Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (</p>
    Formula:C25H22O10
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:482.44
  • RHPS4

    CAS:
    <p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>
    Formula:C22H17F2N2·CH3O4S
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:458.48
  • Irigenin

    CAS:
    <p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>
    Formula:C18H16O8
    Purity:99.50% - 99.85%
    Color and Shape:Solid
    Molecular weight:360.31
  • PD0166285

    CAS:
    <p>PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.</p>
    Formula:C26H27Cl2N5O2
    Purity:99.23%
    Color and Shape:Solid
    Molecular weight:512.43
  • HS-173

    CAS:
    <p>HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).</p>
    Formula:C21H18N4O4S
    Purity:99.33% - 99.64%
    Color and Shape:Solid
    Molecular weight:422.46
  • IITZ-01

    CAS:
    <p>IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)</p>
    Formula:C26H23FN8O
    Purity:99.31%
    Color and Shape:Solid
    Molecular weight:482.51
  • Tubastatin A

    CAS:
    <p>Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.</p>
    Formula:C20H21N3O2
    Purity:97.22% - 99.51%
    Color and Shape:Solid
    Molecular weight:335.4
  • Osthole

    CAS:
    <p>Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.</p>
    Formula:C15H16O3
    Purity:99.93% - 99.96%
    Color and Shape:Fine White Powder
    Molecular weight:244.29
  • 8-​Prenylnaringenin

    CAS:
    <p>8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,</p>
    Formula:C20H20O5
    Purity:98.26% - 99.46%
    Color and Shape:Solid
    Molecular weight:340.37
  • Alantolactone

    CAS:
    <p>Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.</p>
    Formula:C15H20O2
    Purity:99.02% - 99.66%
    Color and Shape:Crystalline Powder
    Molecular weight:232.32
  • Tauroursodeoxycholate dihydrate

    CAS:
    <p>Tauroursodeoxycholate (TUDCA ,Taurolite) dihydrate is a bile acid that reduces Caspase-3, Caspase-12, ERK, reducing endoplasmic reticulum stress mediated death.</p>
    Formula:C26H49NO8S
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:535.73
  • Apomine

    CAS:
    <p>Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂,可在体外促进骨髓瘤细胞的凋亡,并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。</p>
    Formula:C28H52O7P2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:562.66
  • Y-27632 HCl hydrate

    CAS:
    <p>Y-27632 HCl hydrate is an orally effective, ATP-competitive ROCK1/ROCK2 inhibitor (Ki=220 nM/300 nM) that inhibits caspase-3 and suppresses stem cell apoptosis.</p>
    Formula:C14H25Cl2N3O2
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:338.27
  • B355252

    CAS:
    <p>B355252 prevents glutamate-induced cell death and boosts NGF's nerve growth effects.</p>
    Formula:C25H24ClN3O3S2
    Purity:98.73% - 99.92%
    Color and Shape:Solid
    Molecular weight:514.06
  • SC144

    CAS:
    <p>SC144 is an orally active small-molecule gp130 inhibitor.</p>
    Formula:C16H11FN6O
    Purity:99.20%
    Color and Shape:Solid
    Molecular weight:322.3
  • MK-2206 dihydrochloride

    CAS:
    <p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>
    Formula:C25H23Cl2N5O
    Purity:99.228% - 99.94%
    Color and Shape:Solid
    Molecular weight:480.39
  • SKI V

    CAS:
    <p>SKI V is a potent and noncompetitive non-lipid sphingosine kinase (SPHK; SK) inhibitor (GST-hSK,IC50 : 2 μM), and is a PI3K inhibitor(hPI3k,IC50 : 6 μM),</p>
    Formula:C15H10O4
    Purity:98.78%
    Color and Shape:Solid
    Molecular weight:254.24
  • Taurochenodeoxycholic acid sodium

    CAS:
    <p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>
    Formula:C26H44NNaO6S
    Purity:98.23% - 99.45%
    Color and Shape:White To Off-White Powder
    Molecular weight:521.68
  • Diosgenin glucoside

    CAS:
    <p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>
    Formula:C33H52O8
    Purity:97.17% - 99.44%
    Color and Shape:Solid
    Molecular weight:576.76
  • JX06

    CAS:
    <p>JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.</p>
    Formula:C10H16N2O2S4
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:324.51
  • Ziyuglycoside II

    CAS:
    <p>1.</p>
    Formula:C35H56O8
    Purity:99.52% - ≥95%
    Color and Shape:Solid
    Molecular weight:604.81
  • TrxR1-IN-B19

    CAS:
    <p>TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress</p>
    Formula:C21H22O5
    Purity:98.6%
    Color and Shape:Solid
    Molecular weight:354.4
  • UAMC-3203 hydrochloride

    CAS:
    <p>UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.</p>
    Formula:C25H38ClN5O2S
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:508.12
  • C25-140

    CAS:
    <p>C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.</p>
    Formula:C26H31N7O
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:457.57
  • AT9283

    CAS:
    <p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>
    Formula:C19H23N7O2
    Purity:99.83% - 99.98%
    Color and Shape:Solid
    Molecular weight:381.43
  • ABT-737

    CAS:
    <p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>
    Formula:C42H45ClN6O5S2
    Purity:98.15% - >99.99%
    Color and Shape:Solid
    Molecular weight:813.43
  • IMM-01

    CAS:
    <p>IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin</p>
    Formula:C12H17N3O2S
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:267.35
  • Lupiwighteone

    CAS:
    <p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>
    Formula:C20H18O5
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:338.35
  • tubuloside B

    CAS:
    <p>Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.</p>
    Formula:C31H38O16
    Purity:97.59% - 99.72%
    Color and Shape:Solid
    Molecular weight:666.62
  • Piperazine Erastin

    CAS:
    <p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>
    Formula:C35H41ClN6O4
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:645.19
  • CP-31398 dihydrochloride

    CAS:
    <p>CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines.</p>
    Formula:C22H28Cl2N4O
    Purity:98.23%
    Color and Shape:Solid
    Molecular weight:435.4
  • Domatinostat

    CAS:
    <p>Domatinostat (4SC202) is a selective class I HDAC inhibitor. Domatinostat also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).</p>
    Formula:C23H21N5O3S
    Purity:99.57% - 99.74%
    Color and Shape:Solid
    Molecular weight:447.51
  • Vandetanib

    CAS:
    <p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>
    Formula:C22H24BrFN4O2
    Purity:99.7% - >99.99%
    Color and Shape:White Solid
    Molecular weight:475.35
  • XL019

    CAS:
    <p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>
    Formula:C25H28N6O2
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:444.53
  • NQDI-1

    CAS:
    <p>NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).</p>
    Formula:C19H13NO4
    Purity:97.1% - 98.10%
    Color and Shape:Solid
    Molecular weight:319.31
  • ML385

    CAS:
    <p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>
    Formula:C29H25N3O4S
    Purity:98.08% - >99.99%
    Color and Shape:Solid
    Molecular weight:511.59
  • TCPOBOP

    CAS:
    <p>TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.</p>
    Formula:C16H8Cl4N2O2
    Purity:99.7%
    Color and Shape:Solid
    Molecular weight:402.06
  • Actein

    CAS:
    <p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>
    Formula:C37H56O11
    Purity:≥98%
    Color and Shape:Brown Powder
    Molecular weight:676.83
  • OUL35

    CAS:
    <p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>
    Formula:C14H12N2O3
    Purity:99.2%
    Color and Shape:Solid
    Molecular weight:256.26
  • GS-444217

    CAS:
    <p>GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).</p>
    Formula:C23H21N7O
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:411.46
  • β-Ionone

    CAS:
    <p>β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastatic</p>
    Formula:C13H20O
    Purity:98.52%
    Color and Shape:Colourless Liquid Oily
    Molecular weight:192.3
  • UCF 101

    CAS:
    <p>UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.</p>
    Formula:C27H17N3O5S
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:495.51
  • Thalidomide-O-amido-C3-NH2 TFA

    CAS:
    <p>Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.</p>
    Formula:C20H21F3N4O8
    Purity:98.47%
    Color and Shape:Solid
    Molecular weight:502.4
  • L-BUTHIONINE-(S,R)-SULFOXIMINE

    CAS:
    <p>L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.</p>
    Formula:C8H18N2O3S
    Purity:97.07% - ≥98%
    Color and Shape:White Fine Powder
    Molecular weight:222.31
  • Gomisin N

    CAS:
    <p>Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.</p>
    Formula:C23H28O6
    Purity:99.97% - >99.99%
    Color and Shape:Solid
    Molecular weight:400.46
  • OSI-930

    CAS:
    <p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>
    Formula:C22H16F3N3O2S
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:443.44
  • Wogonin

    CAS:
    <p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>
    Formula:C16H12O5
    Purity:98% - 99.8%
    Color and Shape:Yellow Crystal
    Molecular weight:284.26