
Apoptosis
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(127 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(90 products)
- c-RET(61 products)
- p53(63 products)
Found 6170 products of "Apoptosis"
9-Methoxycamptothecin
CAS:9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.Formula:C21H18N2O5Purity:98.49% - 99.56%Color and Shape:SolidMolecular weight:378.38CBL0137
CAS:CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits NF-κB (EC50: 0.47 μM).Formula:C21H24N2O2Purity:99.57% - 99.68%Color and Shape:SolidMolecular weight:336.43VLX600
CAS:VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formula:C17H15N7Purity:98.62%Color and Shape:SolidMolecular weight:317.35NVP-CGM097
CAS:NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).Formula:C38H47ClN4O4Purity:98.77%Color and Shape:SolidMolecular weight:659.26Ref: TM-TQ0231
1mg82.00€5mg195.00€1mL*10mM (DMSO)284.00€10mg324.00€25mg492.00€50mg647.00€100mg893.00€Methyl protodioscin
CAS:Methyl protodioscin boosts HDL, lowers LDL and triglycerides, has anti-cancer effects, and promotes apoptosis via mitochondrial pathways.Formula:C52H86O22Purity:99.308% - 99.73%Color and Shape:SolidMolecular weight:1063.23Alemtuzumab
CAS:Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.
Purity:97.2% (SDS-PAGE); 96.7% (SEC-HPLC) - 98.00%Color and Shape:LiquidMolecular weight:146.04 kDa(S)-CPI203
CAS:CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formula:C19H18ClN5OSPurity:99.01% - 99.92%Color and Shape:SolidMolecular weight:399.9Ref: TM-T6026
2mg34.00€5mg55.00€1mL*10mM (DMSO)58.00€10mg89.00€25mg170.00€50mg269.00€100mg424.00€200mg593.00€Epibrassinolide
CAS:Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator withFormula:C28H48O6Purity:97.57% - 98.11%Color and Shape:SolidMolecular weight:480.68MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.38Amantadine
CAS:Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.Formula:C10H17NPurity:99.73% - 99.94%Color and Shape:Hexakistetrahedral Crystals By Sublimation SolidMolecular weight:151.25RO8994
CAS:RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).Formula:C31H31Cl2FN4O4Purity:99.31% - 99.44%Color and Shape:SolidMolecular weight:613.51Ref: TM-T3517
1mg38.00€2mg50.00€5mg82.00€1mL*10mM (DMSO)100.00€10mg120.00€25mg219.00€50mg344.00€100mg512.00€Temsirolimus
CAS:Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.Formula:C56H87NO16Purity:97.76% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:1030.29Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurity:97.71% - >99.99%Color and Shape:SolidMolecular weight:367.3TPCK
CAS:TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesisFormula:C17H18ClNO3SPurity:97.33%Color and Shape:PowderMolecular weight:351.85Chlorfenapyr
CAS:Chlorfenapyr (AC 303630) is a pyrrole insecticide and converts active substances (insecticidal activity) in insects by a multifunctional oxidaseFormula:C15H11BrClF3N2OPurity:99.33% - 99.49%Color and Shape:Off-White To Light Brown Powder With An Halide OdorMolecular weight:407.61Stattic
CAS:Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.Formula:C8H5NO4SPurity:98.32% - 99.76%Color and Shape:SolidMolecular weight:211.19Ref: TM-T6308
5mg35.00€10mg51.00€1mL*10mM (DMSO)55.00€25mg85.00€50mg124.00€100mg187.00€200mg279.00€500mg465.00€4-Methylsalicylic acid
CAS:4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Formula:C8H8O3Purity:99.64%Color and Shape:Solid Solid CrystallineMolecular weight:152.15Coniferaldehyde
CAS:Coniferaldehyde (Ferulaldehyde) is a member of the class of cinnamaldehydes. Coniferaldehyde has a role as an antifungal agent and a plant metabolite.Formula:C10H10O3Purity:97.71% - 99.96%Color and Shape:SolidMolecular weight:178.18Wogonin
CAS:Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.Formula:C16H12O5Purity:98% - 99.8%Color and Shape:Yellow CrystalMolecular weight:284.26Ref: TM-T2933
5mg34.00€10mg42.00€1mL*10mM (DMSO)52.00€25mg59.00€50mg92.00€100mg131.00€200mg178.00€500mg309.00€Trametinib
CAS:Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Formula:C26H23FIN5O4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:615.39Selonsertib
CAS:Selonsertib (GS-4997), an oral ASK1 inhibitor, may have anti-inflammatory, anti-fibrotic, and anti-cancer effects.Formula:C24H24FN7OPurity:95.04% - 99.53%Color and Shape:SolidMolecular weight:445.49FR 180204
CAS:FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Formula:C18H13N7Purity:98% - 99.74%Color and Shape:SolidMolecular weight:327.34Ref: TM-T1956
1mg40.00€2mg52.00€5mg81.00€1mL*10mM (DMSO)89.00€10mg131.00€25mg210.00€50mg314.00€100mg470.00€VER-50589
CAS:VER-50589 is a potent HSP90 inhibitor.Formula:C19H17ClN2O5Purity:99.96% - >99.99%Color and Shape:SolidMolecular weight:388.8Ref: TM-T2258
1mg42.00€5mg97.00€1mL*10mM (DMSO)97.00€10mg159.00€25mg264.00€50mg404.00€100mg588.00€200mg832.00€Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39LDC000067
CAS:LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.Formula:C18H18N4O3SPurity:98.08% - 99.07%Color and Shape:SolidMolecular weight:370.43Guggulsterone
CAS:Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.Formula:C21H28O2Purity:99.4% - 99.8%Color and Shape:Light Yellow PowderMolecular weight:312.45Ref: TM-T5574
1mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg93.00€25mg152.00€50mg205.00€100mg289.00€200mg432.00€ATH686
CAS:ATH686 is an potent and selective Inhibitor of FLT3.Formula:C25H28F3N7O2Purity:98.07%Color and Shape:SolidMolecular weight:515.53Ref: TM-T7673
1mg101.00€5mg245.00€1mL*10mM (DMSO)268.00€10mg394.00€25mg670.00€50mg888.00€100mg1,224.00€Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurity:97.16% - 99.63%Color and Shape:Almost White SolidMolecular weight:383.37Cyclopiazonic acid
CAS:Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.Formula:C20H20N2O3Purity:99.27% - 99.80%Color and Shape:SolidMolecular weight:336.38Isoliensinine
CAS:Isoliensinine (Isoliensinin) is a natural product, a bisbenzylisoquinoline alkaloid. Isoliensinine has antitumor and antioxidant effects. Cost effective and quality assured.Formula:C37H42N2O6Purity:98.53% - 99.79%Color and Shape:SolidMolecular weight:610.74Ref: TM-T5S1103
1mg34.00€5mg65.00€10mg94.00€1mL*10mM (DMSO)94.00€25mg137.00€50mg193.00€100mg286.00€500mg695.00€Linderalactone
CAS:1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.Formula:C15H16O3Purity:99.79%Color and Shape:SolidMolecular weight:244.29Ref: TM-T5S1897
1mg43.00€5mg84.00€1mL*10mM (DMSO)102.00€10mg119.00€25mg197.00€50mg294.00€100mg437.00€2'-OMe-Guanosine
CAS:2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.Formula:C11H15N5O5Purity:99.93%Color and Shape:White SolidMolecular weight:297.27Capmatinib xHCl
CAS:Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50Formula:C23H18ClFN6OPurity:98.62% - 99.81%Color and Shape:SolidMolecular weight:448.89LY-294002 hydrochloride
CAS:LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.Formula:C19H17NO3·HClPurity:99.95% - 99.98%Color and Shape:SolidMolecular weight:343.81YH239-EE
CAS:YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.Formula:C25H27Cl2N3O4Purity:99.61%Color and Shape:SolidMolecular weight:504.41Stavudine sodium
CAS:Stavudine sodium, an oral HIV-1/2 inhibitor, also hinders mtDNA replication, NLRP3 inflammasome, and Amyloid-β autophagy, prompting apoptosis.Formula:C10H11N2NaO4Color and Shape:SolidMolecular weight:246.198AZD-8055
CAS:AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.Formula:C25H31N5O4Purity:98% - 99.69%Color and Shape:SolidMolecular weight:465.54L67
CAS:L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
Formula:C16H14Br2N4O4Purity:98.34% - 99.56%Color and Shape:SolidMolecular weight:486.11TT-232 TFA(147159-51-1 free base)
CAS:TT2-32 TFA induces a biphasic activation of phosphotyrosine phosphatase activity in human colon tumor cell line, SW620Formula:C47H59F3N10O11S2Purity:99.27% - 99.8%Color and Shape:SolidMolecular weight:1061.16Ref: TM-T23479L
1mg81.00€2mg105.00€5mg168.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€Pyraclostrobin
CAS:Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.Formula:C19H18ClN3O4Purity:99.89%Color and Shape:SolidMolecular weight:387.82Didymin
CAS:Didymin, an antioxidant, may treat neuroblastoma and neurodegeneration by blocking N-Myc and boosting RKIP.Formula:C28H34O14Purity:99.12% - 99.87%Color and Shape:Faintly Beige PowderMolecular weight:594.56UAMC-3203 hydrochloride
CAS:UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.Formula:C25H38ClN5O2SPurity:99.62%Color and Shape:SolidMolecular weight:508.12Ref: TM-T8662
1mgTo inquire2mg49.00€5mg80.00€1mL*10mM (DMSO)89.00€10mg111.00€25mg160.00€50mg202.00€100mg283.00€200mg419.00€GSK2256098
CAS:GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.Formula:C20H23ClN6O2Purity:99.46% - 99.74%Color and Shape:SolidMolecular weight:414.89Ref: TM-T2281
1mg44.00€2mg57.00€5mg84.00€1mL*10mM (DMSO)84.00€10mg130.00€25mg249.00€50mg424.00€100mg625.00€500mg1,314.00€Bomedemstat
CAS:Bomedemstat (IMG-7289),Irreversible LSD1 inhibitor. Active in MPN models. Antineoplastic effects. Used in AML and myelofibrosis research.Formula:C28H34FN7O2Purity:98.23% - 99.00%Color and Shape:SolidMolecular weight:519.61Penicillic acid
CAS:Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.Formula:C8H10O4Purity:98%Color and Shape:Needles From Petroleum Ether Slight Yellow PowderMolecular weight:170.16Capmatinib
CAS:Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.Formula:C23H17FN6OPurity:99.24%Color and Shape:SolidMolecular weight:412.42Ref: TM-T1963
5mg48.00€1mL*10mM (DMSO)50.00€10mg63.00€25mg78.00€50mg90.00€100mg124.00€200mg158.00€500mg255.00€Cytochalasin H
CAS:Cytochalasin H ((16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate) is a potent
Formula:C30H39NO5Purity:98.04%Color and Shape:SolidMolecular weight:493.63Ref: TM-T21513
1mg97.00€2mg142.00€5mg226.00€10mg340.00€25mg553.00€50mg735.00€100mg1,008.00€200mg1,359.00€2,4,6-Triiodophenol
CAS:2,4,6-Triiodophenol: iodinated byproduct from sewage chlorination, disrupts thyroid function, used to study deiodinase.Formula:C6H3I3OPurity:98.11%Color and Shape:Grey To Tan To Brown PowderMolecular weight:471.82-Methoxyestradiol
CAS:2-ME2, an estradiol derivative, hinders angiogenesis and tumor growth, causes cell apoptosis, and stops mitosis.Formula:C19H26O3Purity:98% - 99.95%Color and Shape:Off-White SolidMolecular weight:302.41Buprofezin
CAS:Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.Formula:C16H23N3OSPurity:99.02% - 99.73%Color and Shape:White To Pale Yellow Crystalline PowderMolecular weight:305.44BML-277
CAS:BML-277 (C 3742) is a selective checkpoint kinase 2 (Chk2) inhibitor.Formula:C20H14ClN3O2Purity:98.03% - ≥95%Color and Shape:Tan SolidMolecular weight:363.8Ref: TM-T2033
2mg34.00€5mg49.00€1mL*10mM (DMSO)54.00€10mg80.00€25mg148.00€50mg250.00€100mg356.00€200mg522.00€Pyrazoloadenine
CAS:Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) is the inhibitor of human xanthine oxidase.Formula:C5H5N5Purity:99.02%Color and Shape:Beige PowderMolecular weight:135.13MK-4101
CAS:MK-4101 inhibits Hedgehog pathway, causing apoptosis and reduced proliferation in cancer cells.Formula:C24H24F5N5OPurity:98.2% - 99.13%Color and Shape:SolidMolecular weight:493.47RRX-001
CAS:RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activityFormula:C5H6BrN3O5Purity:99.91% - ≥95%Color and Shape:SolidMolecular weight:268.02Ref: TM-T7400
1mg50.00€2mg73.00€5mg109.00€1mL*10mM (DMSO)120.00€10mg144.00€25mg264.00€50mg462.00€100mg673.00€500mg1,404.00€AMG-337
CAS:AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 inhibits MET kinase activity (IC50: < 5 nM).Formula:C23H22FN7O3Purity:99.26% - 99.9%Color and Shape:SolidMolecular weight:463.46Ref: TM-T3209
1mg38.00€2mg50.00€5mg80.00€1mL*10mM (DMSO)81.00€10mg117.00€25mg187.00€50mg333.00€100mg495.00€200mg710.00€Ac-DEVD-pNA
CAS:Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.Formula:C26H34N6O13Purity:>99.99%Color and Shape:WhiteMolecular weight:638.58Ref: TM-T7816
2mg34.00€5mg57.00€10mg75.00€1mL*10mM (DMSO)79.00€25mg160.00€50mg231.00€100mg335.00€200mg477.00€Dracorhodin perchlorate
CAS:Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer.
Formula:C17H15ClO7Purity:98.31% - ≥95%Color and Shape:SolidMolecular weight:366.75PFK-158
CAS:PFK-158 is an effective and specific inhibitor PFKFB3.Formula:C18H11F3N2OPurity:95.49% - 99.16%Color and Shape:SolidMolecular weight:328.29Ref: TM-T3105
1mg34.00€2mg46.00€5mg66.00€1mL*10mM (DMSO)73.00€10mg90.00€25mg170.00€50mg259.00€100mg409.00€Mivebresib
CAS:Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.Formula:C22H19F2N3O4SPurity:98.74% - 99.32%Color and Shape:SolidMolecular weight:459.47Ref: TM-T3712
1mg55.00€2mg78.00€5mg92.00€1mL*10mM (DMSO)94.00€10mg150.00€25mg244.00€50mg437.00€100mg625.00€Prexasertib Mesylate Hydrate
CAS:Prexasertib Mesylate Hydrate is a potent CHK1 inhibitor (IC50<1nM), also inhibits CHK2, RSK1, induces DNA breaks, apoptosis, and has anti-tumor effects.Formula:C19H25N7O6SColor and Shape:SolidMolecular weight:479.51Karanjin
CAS:Karanjin, a flavonoid from karanja seeds, boosts GLUT4, AMPK in muscles, and triggers cancer cell apoptosis.Formula:C18H12O4Purity:99.01%Color and Shape:SolidMolecular weight:292.29Ref: TM-T2S0820
1mg46.00€1mL*10mM (DMSO)94.00€5mg96.00€10mg145.00€25mg259.00€50mg385.00€100mg557.00€200mg790.00€Nimustine Hydrochloride
CAS:Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.Formula:C9H14Cl2N6O2Purity:98.80%Color and Shape:SolidMolecular weight:309.15Ref: TM-T5017
2mg34.00€5mg49.00€1mL*10mM (DMSO)50.00€10mg71.00€25mg92.00€50mg152.00€100mg268.00€200mg398.00€Aristolactam I
CAS:Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Formula:C17H11NO4Purity:98.98% - 99.96%Color and Shape:SolidMolecular weight:293.27Ref: TM-T3S1227
1mg57.00€5mg133.00€1mL*10mM (DMSO)172.00€10mg205.00€25mg350.00€50mg515.00€100mg735.00€Vistusertib
CAS:Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formula:C25H30N6O3Purity:97.08% - 99.06%Color and Shape:SolidMolecular weight:462.54Ref: TM-T1961
1mg34.00€5mg71.00€1mL*10mM (DMSO)79.00€10mg111.00€25mg170.00€50mg225.00€100mg358.00€200mg530.00€C188-9
CAS:C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.Formula:C27H21NO5SPurity:98.07% - >99.99%Color and Shape:SolidMolecular weight:471.52Ref: TM-T4650
1mg43.00€2mg56.00€1mL*10mM (DMSO)90.00€5mg93.00€10mg116.00€25mg236.00€50mg376.00€100mg562.00€500mg1,198.00€1g1,839.00€KRAS inhibitor-9
CAS:KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formula:C13H9ClN2S2Purity:99.66%Color and Shape:SolidMolecular weight:292.81Ref: TM-T8756
1mg57.00€2mg81.00€5mg113.00€1mL*10mM (DMSO)136.00€10mg178.00€25mg334.00€50mg485.00€100mg622.00€GSK2656157
CAS:GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.Formula:C23H21FN6OPurity:98.59% - >99.99%Color and Shape:SolidMolecular weight:416.45Ref: TM-T2654
2mg34.00€5mg52.00€1mL*10mM (DMSO)52.00€10mg77.00€25mg135.00€50mg245.00€100mg442.00€200mg598.00€2-Chloroadenosine
CAS:2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectivelyFormula:C10H12ClN5O4Purity:99.23%Color and Shape:White PowderMolecular weight:301.69L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Formula:C8H18N2O3SPurity:97.07% - ≥98%Color and Shape:White Fine PowderMolecular weight:222.31PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purity:99.22%Color and Shape:SolidMolecular weight:185.22Ref: TM-T6954
5mg49.00€1mL*10mM (DMSO)54.00€10mg70.00€25mg133.00€50mg195.00€100mg349.00€200mg518.00€500mg830.00€XL019
CAS:XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formula:C25H28N6O2Purity:99.19%Color and Shape:SolidMolecular weight:444.53Ref: TM-T3072
2mg43.00€5mg63.00€1mL*10mM (DMSO)78.00€10mg92.00€25mg150.00€50mg215.00€100mg321.00€200mg477.00€3,4-Dicaffeoylquinic acid
CAS:3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.Formula:C25H24O12Purity:96.33% - 98.82%Color and Shape:SolidMolecular weight:516.45Ref: TM-T6S1525
1mg40.00€5mg80.00€10mg101.00€1mL*10mM (DMSO)103.00€25mg167.00€50mg240.00€100mg355.00€500mg845.00€Importazole
CAS:Importazole is an inhibitor of the nuclear transport receptor importin-β.Formula:C20H22N4Purity:99.6% - >99.99%Color and Shape:SolidMolecular weight:318.42Ref: TM-T3445
5mg49.00€1mL*10mM (DMSO)54.00€10mg69.00€25mg144.00€50mg215.00€100mg356.00€200mg532.00€500mg852.00€tubuloside B
CAS:Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.
Formula:C31H38O16Purity:97.59% - 99.72%Color and Shape:SolidMolecular weight:666.62Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Formula:C28H24FN3O5Purity:99.68% - 99.88%Color and Shape:SolidMolecular weight:501.51C25-140
CAS:C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.Formula:C26H31N7OPurity:98.81%Color and Shape:SolidMolecular weight:457.57Ziyuglycoside II
CAS:1.Formula:C35H56O8Purity:99.52% - ≥95%Color and Shape:SolidMolecular weight:604.81MK-2206 dihydrochloride
CAS:MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent andFormula:C25H23Cl2N5OPurity:99.228% - 99.94%Color and Shape:SolidMolecular weight:480.39Ref: TM-T1952
2mg34.00€5mg49.00€1mL*10mM (DMSO)52.00€10mg66.00€25mg90.00€50mg137.00€100mg205.00€200mg334.00€500mg552.00€XI-006
CAS:NSC-207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and regulates MDM2, an E3 ligase.Formula:C11H13N5O4Purity:99.51%Color and Shape:SolidMolecular weight:279.25Ref: TM-T6610
1mg52.00€2mg77.00€1mL*10mM (DMSO)108.00€5mg113.00€10mg177.00€25mg409.00€50mg605.00€100mg860.00€500mg1,728.00€Tauroursodeoxycholate dihydrate
CAS:Tauroursodeoxycholate (TUDCA ,Taurolite) dihydrate is a bile acid that reduces Caspase-3, Caspase-12, ERK, reducing endoplasmic reticulum stress mediated death.Formula:C26H49NO8SPurity:99.82%Color and Shape:SolidMolecular weight:535.73Eribulin mesylate
CAS:Eribulin mesylate (E7389), a microtubule inhibitor, treats metastatic breast cancer by halting cell division.Formula:C41H63NO14SPurity:97.02% - >99.99%Color and Shape:SolidMolecular weight:826Ruxolitinib
CAS:Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formula:C17H18N6Purity:99.4% - >99.99%Color and Shape:SolidMolecular weight:306.36Ref: TM-T1829
5mg55.00€1mL*10mM (DMSO)62.00€10mg71.00€25mg96.00€50mg110.00€100mg146.00€200mg231.00€500mg393.00€Isosilybin A
CAS:Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (Formula:C25H22O10Purity:98.79%Color and Shape:SolidMolecular weight:482.44SR-318
CAS:SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).Formula:C27H33N5O2Purity:99.74%Color and Shape:SolidMolecular weight:459.58Ref: TM-T12997
2mg35.00€5mg55.00€1mL*10mM (DMSO)55.00€10mg92.00€25mg166.00€50mg259.00€100mg371.00€200mg533.00€Lumichrome
CAS:Lumichrome, a riboflavin metabolite, influences plant growth, ascidian metamorphosis, bacterial communication, and blocks riboflavin uptake.Formula:C12H10N4O2Purity:99.69% - 99.93%Color and Shape:SolidMolecular weight:242.23Tauroursodeoxycholate sodium
CAS:Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.Formula:C26H44NNaO6SPurity:97.90%Color and Shape:SolidMolecular weight:521.69Tetramethylcurcumin
CAS:Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it alsoFormula:C25H28O6Purity:97.69% - 99.94%Color and Shape:SolidMolecular weight:424.49Nutlin-3b
CAS:Nutlin-3b, a less potent (+)-enantiomer of Nutlin-3, inhibits p53/MDM2 at IC50: 13.6 μM, 150x weaker than Nutlin-3a.Formula:C30H30Cl2N4O4Purity:98.83%Color and Shape:SolidMolecular weight:581.49Trigonelline
CAS:Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.Formula:C7H7NO2Purity:97.585% - 99.49%Color and Shape:Prisms Aqueous From Alcohol + Water SolidMolecular weight:137.14SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Formula:C26H32N4O2Purity:97.73%Color and Shape:SolidMolecular weight:432.56Ref: TM-T9073
1mg34.00€2mg49.00€5mg73.00€1mL*10mM (DMSO)89.00€10mg108.00€25mg203.00€50mg306.00€100mg459.00€Anagrelide hydrochloride
CAS:Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.
Formula:C10H7Cl2N3O·HClPurity:99.58%Color and Shape:Off-White PowderMolecular weight:292.55Lanperisone
CAS:Lanperisone is a muscle relaxant.Formula:C15H18F3NOColor and Shape:SolidMolecular weight:285.3AT7519 Hydrochloride
CAS:AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.Formula:C16H18Cl3N5O2Purity:99.66% - 99.9%Color and Shape:SolidMolecular weight:418.71INH6
CAS:INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment.Formula:C19H18N2OSPurity:98.81%Color and Shape:SolidMolecular weight:322.42PHA-793887
CAS:PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.Formula:C19H31N5O2Purity:98.02% - >99.99%Color and Shape:SolidMolecular weight:361.48Ref: TM-T2113
2mg34.00€5mg49.00€1mL*10mM (DMSO)50.00€10mg75.00€25mg114.00€50mg185.00€100mg298.00€200mg444.00€Oxibendazole
CAS:Oxibendazole: a benzimidazole antiparasitic for horses and pets against various worms.Formula:C12H15N3O3Purity:99.3% - 99.88%Color and Shape:Crystalline SolidMolecular weight:249.27T0901317
CAS:T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).Formula:C17H12F9NO3SPurity:98% - 99.64%Color and Shape:SolidMolecular weight:481.33Benzyl isothiocyanate
CAS:BITC, found in cruciferous veggies, exhibits anticancer, antimicrobial, and immunomodulatory effects.Formula:C8H7NSPurity:99.25% - 99.83%Color and Shape:Clear Yellow LiquidMolecular weight:149.21Melatonin
CAS:Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.Formula:C13H16N2O2Purity:98% - 99.89%Color and Shape:Pale Yellow Leaflets From Benzene SolidMolecular weight:232.28

