NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 445 products of "NF-κB"
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Berbamine
CAS:<p>Berbamine is a natural product extracted from Phellodendron amurense.</p>Formula:C37H40N2O6Purity:98.92% - 99.67%Color and Shape:White Crystal PowderMolecular weight:608.72Dauricine
CAS:<p>1.</p>Formula:C38H44N2O6Purity:99.24% - 99.75%Color and Shape:White PowderMolecular weight:624.77Dendrophenol
CAS:<p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>Formula:C17H20O5Purity:98.2% - 99.36%Color and Shape:SolidMolecular weight:304.34SC-514
CAS:<p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>Formula:C9H8N2OS2Purity:99.88% - >99.99%Color and Shape:SolidMolecular weight:224.3yangonin
CAS:<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Formula:C15H14O4Purity:98.82% - 99.55%Color and Shape:Pale Yellow PowderMolecular weight:258.27Iron sucrose
CAS:<p>Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.</p>Formula:C18H24Fe2O24Purity:99.97%Color and Shape:SolidMolecular weight:736.1Neochlorogenic acid
CAS:<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Formula:C16H18O9Purity:99.12% - 99.54%Color and Shape:White PowderMolecular weight:354.31Triacetylresveratrol
CAS:<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formula:C20H18O6Purity:99.81%Color and Shape:Off White PowderMolecular weight:354.35Micheliolide
CAS:<p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>Formula:C15H20O3Purity:98% - 99.37%Color and Shape:SolidMolecular weight:248.32Licochalcone D
CAS:<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Formula:C21H22O5Purity:99.03% - 99.9%Color and Shape:SolidMolecular weight:354.4Nitidine chloride
CAS:<p>1.</p>Formula:C21H18ClNO4Purity:96.59% - 98.91%Color and Shape:SolidMolecular weight:383.82Rhoifolin
CAS:<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Formula:C27H30O14Purity:98.11% - 98.58%Color and Shape:SolidMolecular weight:578.52Ginsenoside Rb1
CAS:<p>Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.</p>Formula:C54H92O23Purity:99.12% - 99.76%Color and Shape:SolidMolecular weight:1109.29GSK481
CAS:<p>GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.</p>Formula:C21H19N3O4Purity:98.97%Color and Shape:SolidMolecular weight:377.39Convallatoxin
CAS:<p>Convallatoxin is a natural product.</p>Formula:C29H42O10Purity:99.27% - 99.53%Color and Shape:Prisms From Methanol + Ether SolidMolecular weight:550.64Cornuside
CAS:<p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>Formula:C24H30O14Purity:99.86% - >99.99%Color and Shape:SolidMolecular weight:542.49Bortezomib
CAS:<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Formula:C19H25BN4O4Purity:97.79% - >99.99%Color and Shape:Yellow SolidMolecular weight:384.24Benzoyloxypaeoniflorin
CAS:<p>Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.</p>Formula:C30H32O13Purity:98.52% - 99.96%Color and Shape:SolidMolecular weight:600.57Pyrrolidinedithiocarbamate ammonium
CAS:<p>Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide</p>Formula:C5H12N2S2Purity:98% - >99.99%Color and Shape:Off-White To Pale Yellow CrystalsMolecular weight:164.29Sodium Aescinate
CAS:<p>Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.</p>Formula:C54H83NaO23Purity:95.17%Color and Shape:SolidMolecular weight:1123.21Specnuezhenide
CAS:<p>Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.</p>Formula:C31H42O17Purity:98% - 99.93%Color and Shape:SolidMolecular weight:686.66γ-Tocotrienol
CAS:<p>γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.</p>Formula:C28H42O2Purity:97.27% - 98.13%Color and Shape:SolidMolecular weight:410.63Ginsenoside Rk3
CAS:<p>Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.</p>Formula:C36H60O8Purity:99.33% - 99.88%Color and Shape:SolidMolecular weight:620.86MLN120B
CAS:<p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>Formula:C19H15ClN4O2Purity:98.92%Color and Shape:SolidMolecular weight:366.8PTP1B-IN-1
CAS:<p>PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)</p>Formula:C8H8N2O3SPurity:99.27%Color and Shape:SolidMolecular weight:212.23MD2-TLR4-IN-1
CAS:<p>MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.</p>Formula:C22H14Cl2N4OPurity:97.74%Color and Shape:SolidMolecular weight:421.28Rubiadin-1-methyl ether
CAS:<p>Rubiadin-1-methyl ether: a natural inhibitor of bone resorption, blocking NF-κB p65 phosphorylation and IκBα degradation.</p>Formula:C16H12O4Purity:98.32%Color and Shape:SolidMolecular weight:268.26Rhynchophylline
CAS:<p>Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.</p>Formula:C22H28N2O4Purity:99.44% - 99.98%Color and Shape:Red Brown Or White Fine PowderMolecular weight:384.47ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Formula:C11H12O4Purity:97.79%Color and Shape:SolidMolecular weight:208.21GSK583
CAS:<p>GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).</p>Formula:C20H19FN4O2SPurity:98.68% - 99.81%Color and Shape:SolidMolecular weight:398.45Isovitexin
CAS:<p>1.</p>Formula:C21H20O10Purity:99.79% - 99.97%Color and Shape:SolidMolecular weight:432.38Denosumab
CAS:<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Formula:C6404H9912N1724O2004S50Purity:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Color and Shape:LiquidMolecular weight:144.71 kDaJTP 0819958 - HOIPIN-1
<p>JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.</p>Formula:C17H13NaO4Purity:99.95%Color and Shape:SolidMolecular weight:304.27Diethylmaleate
CAS:<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Formula:C8H12O4Purity:98%Color and Shape:Colourless LiquidMolecular weight:172.18Chelidonic acid
CAS:<p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>Formula:C7H4O6Purity:99.03%Color and Shape:SolidMolecular weight:184.1Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Formula:C141H210N32O44SPurity:98%Color and Shape:SolidMolecular weight:3089.43Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formula:C32H22O10Purity:98% - 99.72%Color and Shape:SolidMolecular weight:566.51AZD3264
CAS:<p>AZD3264 is a new type IKK2 inhibitor.</p>Formula:C21H23N5O4SPurity:98.98% - 99.17%Color and Shape:SolidMolecular weight:441.5Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purity:95.1% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84Rocaglamide
CAS:<p>Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.</p>Formula:C29H31NO7Purity:95.32% - 99.67%Color and Shape:SolidMolecular weight:505.56Curculigoside
CAS:<p>1.</p>Formula:C22H26O11Purity:99.85%Color and Shape:SolidMolecular weight:466.44Ethacrynic acid
CAS:<p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。</p>Formula:C13H12Cl2O4Purity:98.61% - 99.85%Color and Shape:Crystals Physical Description White Solid (Ntp 1992)Molecular weight:303.14Quinoclamine
CAS:<p>Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.</p>Formula:C10H6ClNO2Purity:99.13% - 99.28%Color and Shape:Orange PowderMolecular weight:207.617,4'-Dihydroxyflavone
CAS:<p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>Formula:C15H10O4Purity:99.39% - 99.6%Color and Shape:SolidMolecular weight:254.24Rucaparib
CAS:<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formula:C19H18FN3OPurity:98.24% - 99.80%Color and Shape:SolidMolecular weight:323.36Geranylgeraniol
CAS:<p>Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.</p>Formula:C20H34OPurity:99.17% - ≥98%Color and Shape:SolidMolecular weight:290.48Adelmidrol
CAS:<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36GSK2982772
CAS:<p>GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.</p>Formula:C20H19N5O3Purity:99.27% - 99.31%Color and Shape:SolidMolecular weight:377.4IRAK inhibitor 1
CAS:<p>IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).</p>Formula:C17H19N5Purity:97.5% - 99.89%Color and Shape:SolidMolecular weight:293.3714-Deoxy-11,12-didehydroandrographolide
CAS:<p>14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.</p>Formula:C20H28O4Purity:99.13% - 99.93%Color and Shape:SolidMolecular weight:332.43Rucaparib Phosphate
CAS:<p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>Formula:C19H18FN3O·H3PO4Purity:99.37%Color and Shape:SolidMolecular weight:421.36Damascenone
CAS:<p>Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.</p>Formula:C13H18OPurity:98.03%Color and Shape:Colorless LiquidMolecular weight:190.28IQ-1S free acid
CAS:<p>IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.</p>Formula:C15H9N3OPurity:97.92% - 99.05%Color and Shape:SolidMolecular weight:247.2520(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Formula:C42H72O13Purity:98.11% - 99.93%Color and Shape:SolidMolecular weight:785.012,4-Diamino-6-hydroxypyrimidine
CAS:<p>2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis</p>Formula:C4H6N4OPurity:99.82%Color and Shape:White Solid CrystalsMolecular weight:126.12Andrographolide
CAS:<p>Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential</p>Formula:C20H30O5Purity:99.39% - 99.97%Color and Shape:PowderMolecular weight:350.458-Deoxygartanin
CAS:<p>8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has</p>Formula:C23H24O5Purity:99.04% - 99.88%Color and Shape:SolidMolecular weight:380.43TAK-243
CAS:<p>TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).</p>Formula:C19H20F3N5O5S2Purity:98.09% - 98.93%Color and Shape:SolidMolecular weight:519.52Caffeic Acid Phenethyl Ester
CAS:<p>CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.</p>Formula:C17H16O4Purity:99.18% - 99.35%Color and Shape:Less Transparent Liquid Colorless Transparent LiquidMolecular weight:284.31Betulinic acid
CAS:<p>Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.</p>Formula:C30H48O3Purity:99.12% - 99.7%Color and Shape:White Crystalline PowderMolecular weight:456.7Indacaterol
CAS:<p>Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.</p>Formula:C24H28N2O3Purity:99.96%Color and Shape:SolidMolecular weight:392.49Rucaparib monocamsylate
CAS:<p>Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor. Rucaparib Camsylate also displays binding affinity to eight other PARP domains.</p>Formula:C29H34FN3O5SPurity:99.82%Color and Shape:SolidMolecular weight:555.66Tryptanthrin
CAS:<p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>Formula:C15H8N2O2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:248.24Sauchinone
CAS:<p>Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.</p>Formula:C20H20O6Purity:>99.99%Color and Shape:SolidMolecular weight:356.37GSK547
CAS:<p>GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.</p>Formula:C20H18F2N6OPurity:99.17%Color and Shape:SolidMolecular weight:396.39Sanggenon C
CAS:<p>Sanggenon C inhibits NF-κB activity, the expression of inducible nitric oxide synthase, tumor necrosis factor-α-stimulated cell adhesion and the expression of vascular cell adhesion molecule-1 in RAW264.7 cells. Cost-effective and quality-assured.</p>Formula:C40H36O12Purity:97.76% - 99.76%Color and Shape:SolidMolecular weight:708.71HOMOPLANTAGININ
CAS:<p>Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows</p>Formula:C22H22O11Purity:97.63% - 99.66%Color and Shape:SolidMolecular weight:462.4SC75741
CAS:<p>SC75741 is a potent P65 inhibitor with IC50 of 200 nM</p>Formula:C29H23N7O2S2Purity:99.44% - 99.54%Color and Shape:SolidMolecular weight:565.67Sulforaphene
CAS:<p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>Formula:C6H9NOS2Purity:97.55% - 99.19%Color and Shape:Slightly Yellowish LiquidMolecular weight:175.27Ginsenoside Rg5
CAS:<p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>Formula:C42H70O12Purity:98% - 99.65%Color and Shape:SolidMolecular weight:767WAY-169916
CAS:<p>WAY-169916 inhibits ER by blocking NF-kB activity, lacks estrogenic effects.</p>Formula:C17H13F3N2O2Purity:98.63% - 98.64%Color and Shape:SolidMolecular weight:334.29Astilbin
CAS:<p>Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.</p>Formula:C21H22O11Purity:97% - 99.86%Color and Shape:White PowderMolecular weight:450.39Praeruptorin A
CAS:<p>Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin</p>Formula:C21H22O7Purity:99.63% - 99.65%Color and Shape:SolidMolecular weight:386.4Tenuigenin
CAS:<p>Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.</p>Formula:C30H45ClO6Purity:98.9% - 99.53%Color and Shape:SolidMolecular weight:537.13Tectochrysin
CAS:<p>Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.</p>Formula:C16H12O4Purity:99.26%Color and Shape:SolidMolecular weight:268.26INH14
CAS:<p>INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).</p>Formula:C15H16N2OPurity:95.41%Color and Shape:SolidMolecular weight:240.3Picroside II
CAS:<p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>Formula:C23H28O13Purity:98% - 99.83%Color and Shape:SolidMolecular weight:512.46Phorbol 12-myristate 13-acetate
CAS:<p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>Formula:C36H56O8Purity:98.55% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:616.83Handelin
CAS:<p>Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.</p>Formula:C32H40O8Purity:99.02% - 99.345%Color and Shape:SolidMolecular weight:552.66Sciadopitysin
CAS:<p>Sciadopitysin may thwart diabetic bone disease, boost mitochondria, protect osteoblasts, and hinder Aβ aggregation/neurotoxicity.</p>Formula:C33H24O10Purity:98.14% - 99.17%Color and Shape:SolidMolecular weight:580.54HS-1371
CAS:<p>HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.</p>Formula:C24H24N4OPurity:98%Color and Shape:SolidMolecular weight:384.47Okanin
CAS:<p>Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.</p>Formula:C15H12O6Purity:95.19% - 99.4%Color and Shape:SolidMolecular weight:288.25Schisantherin A
CAS:<p>Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.</p>Formula:C30H32O9Purity:98% - 99.989Color and Shape:SolidMolecular weight:536.57Necrostatin 2 racemate
CAS:<p>Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.</p>Formula:C13H12ClN3O2Purity:98% - 99.5%Color and Shape:SolidMolecular weight:277.71Esculentoside H
CAS:<p>Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.</p>Formula:C48H76O21Purity:98.04% - 99.3%Color and Shape:SolidMolecular weight:989.1Isoliquiritin apioside
CAS:<p>Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.</p>Formula:C26H30O13Purity:98.84% - 99.27%Color and Shape:SolidMolecular weight:550.51Ginsenoside Re
CAS:<p>Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.</p>Formula:C48H82O18Purity:99.12% - >99.99%Color and Shape:White PowderMolecular weight:947.15Suberosin
CAS:<p>Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.</p>Formula:C15H16O3Purity:97.08% - 99.26%Color and Shape:SolidMolecular weight:244.29NDMC101
CAS:<p>NDMC101 suppresses dipeptidyl peptidase-IV, NFATc1, and NF-κB in human T cells, modulating immunity.</p>Formula:C13H9ClFNO2Purity:99.89%Color and Shape:SolidMolecular weight:265.67IRAK4-IN-1
CAS:<p>IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.</p>Formula:C19H23N5OPurity:98.18% - 99.85%Color and Shape:SolidMolecular weight:337.42BMS-345541 hydrochloride
CAS:<p>BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).</p>Formula:C14H18ClN5Purity:99.13%Color and Shape:SolidMolecular weight:291.78IKK 16
CAS:<p>IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.</p>Formula:C28H29N5OSPurity:98.76% - 99.61%Color and Shape:SolidMolecular weight:483.63GSK2983559 active metabolite
CAS:<p>GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.</p>Formula:C21H22N4O4S2Purity:97.07% - 99.57%Color and Shape:SolidMolecular weight:458.55NF-κΒ activator 2
CAS:<p>NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM.</p>Formula:C16H11FN2O3Purity:98.12%Color and Shape:SolidMolecular weight:298.27Eurycomalactone
CAS:<p>Eurycomalactone, from Eurycoma longifolia, inhibits NF-κB (IC50 0.5 μM), stops protein synthesis and cyclin D1, spares IκBα and IKK.</p>Formula:C19H24O6Purity:99.48% - 99.87%Color and Shape:SolidMolecular weight:348.39JSH-23
CAS:<p>JSH-23 is an NF-κB inhibitor that inhibits NF-κB transcriptional activity without affecting IκB degradation. JSH-23 is an antioxidant. Cost effective and quality assured.</p>Formula:C16H20N2Purity:98.03% - 99.67%Color and Shape:SolidMolecular weight:240.34GS143
CAS:<p>GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.</p>Formula:C28H19FN2O4Purity:97.67%Color and Shape:SolidMolecular weight:466.46Isodeoxyelephantopin
CAS:<p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>Formula:C19H20O6Purity:99.88%Color and Shape:SolidMolecular weight:344.36IKKγ NBD Inhibitory Peptide acetate
<p>IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.</p>Purity:99.15%Color and Shape:SolidMolecular weight:N/AVamorolone
CAS:<p>Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.</p>Formula:C22H28O4Purity:99.54%Color and Shape:SolidMolecular weight:356.46Robinin
CAS:<p>Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.</p>Formula:C33H40O19Purity:98.78% - 99.13%Color and Shape:SolidMolecular weight:740.66Engeletin
CAS:<p>1.</p>Formula:C21H22O10Purity:99.72% - 99.99%Color and Shape:SolidMolecular weight:434.39Polygalasaponin F
CAS:<p>Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.</p>Formula:C53H86O23Purity:98% - 99.83%Color and Shape:SolidMolecular weight:1091.24Embelin
CAS:<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39Triptolide
CAS:<p>Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation.</p>Formula:C20H24O6Purity:97.19% - 99.97%Color and Shape:White To Off-White SolidMolecular weight:360.4Barlerin
CAS:<p>Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and protective effect on oxygen-glucose deprivation-induced injury</p>Formula:C19H28O12Purity:99.83% - ≥95%Color and Shape:SolidMolecular weight:448.42TBK1/IKKε-IN-5
CAS:<p>TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).</p>Formula:C28H31N7O3Purity:98.77%Color and Shape:SolidMolecular weight:513.59Mollugin
CAS:<p>Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.</p>Formula:C17H16O4Purity:99.87% - ≥95%Color and Shape:SolidMolecular weight:284.31Tyrosol
CAS:<p>Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present most</p>Formula:C8H10O2Purity:99.24% - 99.86%Color and Shape:SolidMolecular weight:138.16PI-1840
CAS:<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47SM-7368
CAS:<p>The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.</p>Formula:C10H5ClN4O5SPurity:99.64%Color and Shape:SolidMolecular weight:328.69IRAK-1-4 Inhibitor I
CAS:<p>IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.</p>Formula:C20H21N5O4Purity:98% - 99.89%Color and Shape:SolidMolecular weight:395.41Tomatidine
CAS:<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>Formula:C27H45NO2Purity:99.94% - 99.98%Color and Shape:SolidMolecular weight:415.6511-Keto-β-boswellic acid
CAS:<p>11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.</p>Formula:C30H46O4Purity:99.68%Color and Shape:SolidMolecular weight:470.68RIPA-56
CAS:<p>RIPA-56 is an inhibitor of RIP1</p>Formula:C13H19NO2Purity:99.53% - 99.93%Color and Shape:SolidMolecular weight:221.3Zimlovisertib
CAS:<p>Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4).</p>Formula:C18H20FN3O4Purity:98.21%Color and Shape:SolidMolecular weight:361.37Malachite green oxalate
CAS:<p>Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.</p>Formula:C23H25N2·C2HO4C2H2O4Color and Shape:Dark Green Crystals With A Metallic LusterMolecular weight:463.51Sarsasapogenin
CAS:<p>Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin.</p>Formula:C27H44O3Purity:90% - 99.73%Color and Shape:White Or Off-Withe PowderMolecular weight:416.64Obtusifolin
CAS:<p>Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.</p>Formula:C16H12O5Purity:99.78% - 99.99%Color and Shape:SolidMolecular weight:284.26Neferine
CAS:<p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>Formula:C38H44N2O6Purity:98.81% - 99.65%Color and Shape:SolidMolecular weight:624.77Gossypin
CAS:<p>Gossypin exhibits multiple medicinal properties and inhibits NF-kappaB, reducing inflammation, cancer growth, and angiogenesis.</p>Formula:C21H20O13Purity:97.57% - 98.97%Color and Shape:SolidMolecular weight:480.38Aconine
CAS:<p>1. Aconine (Jesaconine) is the febrifuge. 2. Aconine possesses gastric anaesthetic props.</p>Formula:C25H41NO9Purity:99.61% - 99.93%Color and Shape:SolidMolecular weight:499.59Madecassic acid
CAS:<p>Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.</p>Formula:C30H48O6Purity:98.80% - 99.69%Color and Shape:SolidMolecular weight:504.7Delanzomib
CAS:<p>Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.</p>Formula:C21H28BN3O5Purity:95.52% - 99.46%Color and Shape:SolidMolecular weight:413.28Deoxyelephantopin
CAS:<p>Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.</p>Formula:C19H20O6Purity:99.6% - 99.71%Color and Shape:SolidMolecular weight:344.36JH-X-119-01
CAS:<p>JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.</p>Formula:C25H20N6O3Purity:98.42%Color and Shape:SolidMolecular weight:452.46Aristolochic acid A
CAS:<p>Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort family of plants.</p>Formula:C17H11NO7Purity:99.85% - 99.97%Color and Shape:Yellow PowderMolecular weight:341.27Indole-3-carbinol
CAS:<p>Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase</p>Formula:C9H9NOPurity:98.59% - >99.99%Color and Shape:SolidMolecular weight:147.17GSK-872
CAS:<p>GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity and inhibits kinase activity.</p>Formula:C19H17N3O2S2Purity:99.87% - 99.94%Color and Shape:SolidMolecular weight:383.493'-Sialyllactose sodium
CAS:<p>3'-Sialyllactose sodium is a prebiotic with anti-inflammatory activity that maintains immune homeostasis and can be used to study inflammation.</p>Formula:C23H38NNaO19Purity:>99.99%Color and Shape:SolidMolecular weight:655.53(S)-(+)-Ibuprofen
CAS:<p>(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).</p>Formula:C13H18O2Purity:99.51% - 99.86%Color and Shape:Colourless Crystalline SolidMolecular weight:206.281,3-Dibenzyl-5-fluorouracil
CAS:<p>1,3-Dibenzyl-5-fluorouracil is a chemical inhibitor that suppresses the formation of osteoclasts, functioning by downregulating the signaling pathways of nuclear factor κB ligand receptor activator (Receptor activator of NF-κB ligand, RANKL) and macrophage colony-stimulating factor (M-CSF). This compound is used in the research of metabolic bone diseases.</p>Formula:C18H15FN2O2Color and Shape:SolidMolecular weight:310.32Gatralimab
CAS:<p>Gatralimab (anti-CD52 mAb) shows successful lymphocyte depletion & repopulation in Phase 1, supporting its study for relapsing MS.</p>Purity:95%Color and Shape:LiquidKamebakaurin
CAS:<p>Kamebakaurin combats liver toxicity, cancer, inflammation, and neuroinflammation by blocking NF-κB, HIF-1α, and key signaling pathways.</p>Formula:C20H30O5Purity:98.05%Color and Shape:SolidMolecular weight:350.45E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formula:C21H30O6Purity:99.52%Color and Shape:SolidMolecular weight:378.46BAY32-5915
CAS:<p>BAY32-5915 is a selective inhibitor of IKKalpha.</p>Formula:C10H7NO3Purity:96.48% - 97%Color and Shape:Yellow Crystalline PowderMolecular weight:189.17IMD-biphenylB
CAS:<p>IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67SZM679
<p>SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.</p>Formula:C27H18F5N3O5SPurity:98%Color and Shape:SolidMolecular weight:591.51NF-κB-IN-3
CAS:<p>NF-κB-IN-3 (Compound 2) is an NF-κB inhibitor (IC50: 0.70 μM) and can be used as an anti-tumour agent.</p>Formula:C24H18ClF3N2O2Color and Shape:SolidMolecular weight:458.861-Dehydro-[10]-gingerdione
CAS:<p>1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.</p>Formula:C21H30O4Color and Shape:SolidMolecular weight:346.46ABD-350
CAS:<p>ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.</p>Formula:C19H22F2O2Color and Shape:SolidMolecular weight:320.37MHY884
CAS:<p>MHY884 inhibits tyrosinase and UVB-triggered NF-κB activation by reducing oxidative stress.</p>Formula:C15H14ClNO3SPurity:98%Color and Shape:SolidMolecular weight:323.79IT-901
CAS:<p>IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.</p>Formula:C17H14N2O4SPurity:98.06%Color and Shape:SolidMolecular weight:342.37IKK2-IN-4
CAS:<p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>Formula:C12H11N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:261.3CID-2858522
CAS:<p>CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).</p>Formula:C28H39N3O3Purity:96.12%Color and Shape:SolidMolecular weight:465.63DHMEQ racemate
CAS:<p>DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ.</p>Formula:C13H11NO5Purity:98%Color and Shape:SolidMolecular weight:261.23AP-1/NF-κB activation inhibitor 1
CAS:<p>AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal</p>Formula:C13H11F3N4O4Purity:99.52% - 99.91%Color and Shape:SolidMolecular weight:344.25APC-0576
CAS:<p>APC-0576, an (S,S)-isomer, blocks NF-kappaB gene activation and may reduce inflammation in human cells.</p>Formula:C23H27N3O3Color and Shape:SolidMolecular weight:393.48Avenanthramide-C methyl ester
CAS:<p>Avenanthramide-C methyl ester blocks IKK/IκB phosphorylation, inhibits NF-κB, and reduces IL-6, IL-8, MCP-1 in endothelial cells (IC50 ~40 μM).</p>Formula:C17H15NO6Color and Shape:SolidMolecular weight:329.3Edasalonexent
CAS:<p>Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.</p>Formula:C31H42N2O3Purity:99.13% - >99.99%Color and Shape:SolidMolecular weight:490.68IMD-ferulic
<p>IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators.</p>Formula:C36H41N7O4Color and Shape:SolidMolecular weight:635.76Ro 106-9920
CAS:<p>Inhibitor of NF-κB activation</p>Formula:C10H7N5OSPurity:98%Color and Shape:SolidMolecular weight:245.26Bay 65-1942 hydrochloride
CAS:<p>Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.</p>Formula:C22H26ClN3O4Color and Shape:SolidMolecular weight:431.91HPN-01
CAS:<p>HPN-01 (IKK inhibitor XII) is an IKK inhibitor that inhibits IKK-α and IKK-ε, prolongs the lifespan of mice, and can be used to study immune disorders.</p>Formula:C19H16ClN3O3SPurity:98.07% - 98.17%Color and Shape:SolidMolecular weight:401.87RIP2 Kinase Inhibitor 3
CAS:<p>RIP2 Kinase Inhibitor 3 is a potent and selective inhibitor of RIP2 with an IC50 of 1 nM.</p>Formula:C19H24N4O3SPurity:99.32% - 99.52%Color and Shape:SolidMolecular weight:388.48NF-κB-IN-2
CAS:<p>NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.</p>Formula:C15H18O3Color and Shape:SolidMolecular weight:246.3Gue1654
CAS:<p>Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.</p>Formula:C23H17N3OS3Purity:98.02% - 98.04%Color and Shape:SolidMolecular weight:447.6GSK319347A
CAS:<p>GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.</p>Formula:C22H19N3O5S2Purity:98.42%Color and Shape:SolidMolecular weight:469.53IKKβ-IN-1
CAS:<p>IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).</p>Formula:C31H30N4O4SColor and Shape:SolidMolecular weight:554.66DMX-129
CAS:<p>DMX-129 is a chemical compound acting as an inhibitor for both ΙΚΚε and TBK-1, demonstrating efficacy with IC50 values of below 30 nM for each [1].</p>Formula:C19H17FN8Color and Shape:SolidMolecular weight:376.39TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Formula:C16H7ClF2O4Purity:99.77%Color and Shape:SolidMolecular weight:336.67Anti-inflammatory agent 21
CAS:<p>Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.</p>Formula:C24H21FO6Color and Shape:SolidMolecular weight:424.42HSR1304
CAS:<p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>Formula:C24H21ClN2O3Color and Shape:SolidMolecular weight:420.89Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Formula:C29H34N2O15Color and Shape:SolidMolecular weight:650.58NF-κB/PON1-IN-1
CAS:<p>NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.</p>Formula:C20H16N6O4S2Color and Shape:SolidMolecular weight:468.51RI-962
CAS:<p>RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.</p>Formula:C28H28N6O2Purity:99.39%Color and Shape:SoildMolecular weight:480.56TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formula:C17H17NOPurity:99.76%Color and Shape:SolidMolecular weight:251.32Bay 65-1942 free base
CAS:<p>Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.</p>Formula:C22H25N3O4Purity:98%Color and Shape:SolidMolecular weight:395.45Asperbisabolane L
<p>Asperbisabolane L, a sesquiterpenoid, combats inflammation by blocking NF-κB signaling and NO in BV-2 cells.</p>Formula:C12H14O3Color and Shape:SolidMolecular weight:206.24TBK1/IKKε-IN-4
CAS:<p>TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM</p>Formula:C28H35N7O4Color and Shape:SolidMolecular weight:533.62PHA-408
CAS:<p>PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2.</p>Formula:C29H27ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:560.02IMD-catechol
CAS:<p>IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.</p>Formula:C31H34N6O3Purity:98%Color and Shape:SolidMolecular weight:538.64NF-κB-IN-8
CAS:<p>NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2.</p>Formula:C24H21N3O3Purity:98%Color and Shape:SolidMolecular weight:399.44CAY10575
CAS:<p>CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.</p>Formula:C22H21N3O6S2Color and Shape:SolidMolecular weight:487.55IMD-biphenylA
CAS:<p>IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties of small molecule immune</p>Formula:C35H33N5O2Purity:98%Color and Shape:SolidMolecular weight:555.67NF-κB-IN-11
CAS:<p>NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.</p>Formula:C19H18O5Purity:98%Color and Shape:SolidMolecular weight:326.34HE 3286
CAS:<p>Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.</p>Formula:C21H30O3Color and Shape:SolidMolecular weight:330.46SP-100030
CAS:<p>SP-100030: Strong NF-κB/AP-1 inhibitor, IC50=50 nM. Reduces IL-2, IL-8, TNF-alpha, and murine CIA.</p>Formula:C14H5ClF9N3OPurity:99.79%Color and Shape:SolidMolecular weight:437.65Zabedosertib
CAS:<p>Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential.</p>Formula:C20H21F3N4O4SPurity:98.54%Color and Shape:SolidMolecular weight:470.47GSK2983559 free acid
CAS:<p>GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.</p>Formula:C21H23N4O7PS2Purity:97.8700% - 98.61%Color and Shape:SolidMolecular weight:538.53B022
CAS:<p>B022 is an NF-κB-induced kinase (NIK) inhibitor that protects the liver from inflammation and injury caused by oxidative stress and toxins.</p>Formula:C19H16ClN5OSPurity:99.74%Color and Shape:SolidMolecular weight:397.88NFATc1-IN-1
CAS:<p>NFATc1-IN-1 (A04) inhibits RANKL-induced osteoclast formation with 1.57 μM IC50, blocking NFATc1 translocation.</p>Formula:C13H8F2INO2Purity:99.64%Color and Shape:SolidMolecular weight:375.11Zharp2-1
CAS:<p>Zharp2-1 is a RIPK2 inhibitor that alleviates MDP-induced peritonitis symptoms in mice and can be used to study inflammatory bowel disease (IBD).</p>Formula:C19H18N3O2PSPurity:99.41%Color and Shape:SolidMolecular weight:383.4RIPK1-IN-9
CAS:<p>RIPK1-IN-9, a potent dihydronaphthone, selectively inhibits RIPK1 with IC50 of 2 nM (U937) and 1.3 nM (L929).</p>Formula:C26H25FN6O2Purity:99.85%Color and Shape:SolidMolecular weight:472.51HS271
CAS:<p>HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM).</p>Formula:C21H24F3N5O2Purity:98.79%Color and Shape:SolidMolecular weight:435.44IRAK4-IN-20
CAS:<p>IRAK4-IN-20 is a potent and orally active IRAK4 inhibitor (IC50:3.55 nM).</p>Formula:C22H25F3N4O3Purity:98.09%Color and Shape:SolidMolecular weight:450.45GSK840
CAS:<p>GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase</p>Formula:C21H23N3O3Purity:99.7%Color and Shape:SolidMolecular weight:365.43PF-184
<p>PF-184: potent IKK-2 inhibitor, selective over 30+ kinases; useful for asthma & COPD research. IC50: 37 nM.</p>Formula:C32H32ClFN6O4Color and Shape:SolidMolecular weight:619.09WEHI-345
CAS:<p>WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.</p>Formula:C22H23N7OPurity:>99.99%Color and Shape:SolidMolecular weight:401.46RIPK1-IN-16
CAS:<p>RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.</p>Formula:C20H19N5O2SPurity:98%Color and Shape:SolidMolecular weight:393.46Ginsenoside Rk1
CAS:<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Formula:C42H70O12Purity:98.46% - 99.13%Color and Shape:SolidMolecular weight:767PF 184
CAS:<p>IKKβ inhibitor</p>Formula:C32H32ClFN6O4Purity:98%Color and Shape:SolidMolecular weight:619.09RIP1 kinase inhibitor 4
CAS:<p>RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].</p>Formula:C23H23N5Purity:98%Color and Shape:SolidMolecular weight:369.46IMD-biphenylC
CAS:<p>IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.</p>Formula:C35H33N5O3Purity:98%Color and Shape:SolidMolecular weight:571.67CGA-JK3
CAS:<p>CGA-JK3 is an IkappaB kinase inhibitor in innate immune process.</p>Formula:C15H19NO3Purity:98%Color and Shape:SolidMolecular weight:261.32PK68
CAS:<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Formula:C22H24N4O3SPurity:98.09% - 99.64%Color and Shape:SolidMolecular weight:424.52IRAK inhibitor 3
CAS:<p>IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.</p>Formula:C21H21N5O4SPurity:98.86%Color and Shape:SolidMolecular weight:439.49IMD-vanillin
CAS:<p>IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.</p>Formula:C37H45N7O4Purity:98%Color and Shape:SolidMolecular weight:651.8TBK1-IN-1
CAS:<p>TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.</p>Formula:C27H37N7O2Purity:>99.99%Color and Shape:SolidMolecular weight:491.63
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