Membrane Transporter/Ion Channel
Membrane transporter and ion channel inhibitors are compounds that block the function of proteins responsible for the transport of ions, nutrients, and other molecules across cell membranes. These inhibitors are crucial for studying the regulation of cellular homeostasis, signal transduction, and neurotransmission. Membrane transporter and ion channel inhibitors are also important in developing treatments for disorders such as epilepsy, cardiovascular diseases, and metabolic syndromes. At CymitQuimica, we provide a diverse selection of high-quality membrane transporter and ion channel inhibitors to support your research in physiology, neuroscience, and pharmacology.
Subcategories of "Membrane Transporter/Ion Channel"
- ABC(3 products)
- ATPase(92 products)
- Adiponectin receptor(5 products)
- CFTR(66 products)
- CGRP Receptor(55 products)
- Calcium Channel(578 products)
- Chloride channel(53 products)
- GABA Receptor(367 products)
- Monoamine Transporter(30 products)
- Monocarboxylate transporter(18 products)
- NKCC(2 products)
- NPC1L1(1 products)
- Na-K-Cl cotransporter(9 products)
- OAT(31 products)
- OCT(7 products)
- P-gp(56 products)
- Potassium Channel(318 products)
- Proton pump(42 products)
- SGLT(32 products)
- Sodium Channel(273 products)
- TRP/TRPV Channel(97 products)
Show 13 more subcategories
Found 2690 products for "Membrane Transporter/Ion Channel".
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Nefiracetam
CAS:Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.Formula:C14H18N2O2Purity:97.37%Color and Shape:SolidMolecular weight:246.3DCPIB
CAS:DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFormula:C22H28Cl2O4Purity:99.79% - 99.87%Color and Shape:SolidMolecular weight:427.36Ref: TM-T10979
2mg39.00€5mg57.00€1mL*10mM (DMSO)63.00€10mg87.00€25mg177.00€50mg301.00€100mg485.00€200mg690.00€NaV1.7 inhibitor-1
CAS:NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).Formula:C23H30FNO4SPurity:99.89%Color and Shape:SolidMolecular weight:435.55Ref: TM-T12181
1mg99.00€5mg241.00€1mL*10mM (DMSO)265.00€10mg385.00€25mg663.00€50mg888.00€100mg1,305.00€3,4,5-Trimethoxycinnamic acid
CAS:3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at theFormula:C12H14O5Purity:98.91%Color and Shape:SolidMolecular weight:238.24Mephenesin
CAS:Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.Formula:C10H14O3Purity:99.49% - 99.87%Color and Shape:SolidMolecular weight:182.22Emamectin Benzoate
CAS:Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropodsFormula:C56H81NO15Purity:98.68%Color and Shape:SolidMolecular weight:1008.256Trimethadione
CAS:Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity.Formula:C6H9NO3Purity:99.67% - >99.99%Color and Shape:Yellow SolidMolecular weight:143.14IK1 inhibitor PA-6
CAS:IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouseFormula:C31H32N4O2Purity:98.9%Color and Shape:SolidMolecular weight:492.61Boc-LRR-AMC TFA
Boc-LRR-AMC TFA is a fluorogenic protease substrate for detecting trypsin-like activity in the 26S proteasome or 20S proteasome core.Formula:C35H53F3N10O9Purity:97.70%Color and Shape:SolidMolecular weight:814.85UK-124114
CAS:Selamectin, a derivative of ivermectin, is a macrocyclic lactone that enhances chloride channels in nematodes, inhibiting H. contortus larval growth.Formula:C43H63NO11Purity:99.64%Color and Shape:White SolidMolecular weight:769.961-EBIO
CAS:1-EBIO (1-EBIO) is a calium channel agonist.Formula:C9H10N2OPurity:98.75% - 99.96%Color and Shape:SolidMolecular weight:162.19QX-314 chloride
CAS:QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.Formula:C16H27ClN2OPurity:99.73%Color and Shape:SolidMolecular weight:298.85Indapamide
CAS:Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.Formula:C16H16ClN3O3SPurity:98.97% - 99.83%Color and Shape:SolidMolecular weight:365.83MRZ 2-514
CAS:MRZ 2-514 (8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one) is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with KiFormula:C11H6BrN3O3Purity:98.45%Color and Shape:SolidMolecular weight:308.09Ref: TM-T12110
1mg92.00€5mg192.00€1mL*10mM (DMSO)212.00€10mg313.00€25mg620.00€50mg1,044.00€100mg1,404.00€Vocacapsaicin hydrochloride
CAS:Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.Formula:C26H42ClN3O4Purity:99.66% - 99.80%Color and Shape:SolidMolecular weight:496.08Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Formula:C11H12N2O2Purity:99.67%Color and Shape:White SolidMolecular weight:204.23Synta66
CAS:Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease.Formula:C20H17FN2O3Purity:99.57% - 99.84%Color and Shape:SolidMolecular weight:352.36Ref: TM-T13047
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg80.00€25mg147.00€50mg227.00€100mg339.00€200mg482.00€Caldaret HCl
CAS:Caldaret HCl is an intracellular Ca2+ modulator that regulates calcium homeostasis at the sarcoplasmic reticulum and cell membrane, and can be used to study acute myocardial infarction and heart failure.Formula:C11H17ClN2O3SPurity:99.16%Color and Shape:Yellow SolidMolecular weight:292.78Z433927330
CAS:Z433927330 is a potent and selective Aquaporin-7 (AQP7) inhibitor(IC50s of 0.2).Formula:C20H20N4O3Purity:99.64%Color and Shape:SolidMolecular weight:364.4Bemegride
CAS:Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.Formula:C8H13NO2Purity:99.89%Color and Shape:SolidMolecular weight:155.19Fluxametamide
CAS:Fluxametamide, an isoxazoline insecticide, targets insect chloride channels with IC50s of 1.95 nM (GABA) and 225 nM (glutamate).Formula:C20H16Cl2F3N3O3Purity:99.49%Color and Shape:SolidMolecular weight:474.26Tetracaine hydrochloride
CAS:Tetracaine HCl (Pontocaine), a potent local anesthetic and antipruritic, is used in eye care and for surface/spinal anesthesia.Formula:C15H25ClN2O2Purity:99.72% - 99.94%Color and Shape:White SolidMolecular weight:300.82Acetohexamide
CAS:Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity.Formula:C15H20N2O4SPurity:99.01% - 99.19%Color and Shape:White SolidMolecular weight:324.40Ropivacaine
CAS:Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Formula:C17H26N2OPurity:97.75% - >99.99%Color and Shape:SolidMolecular weight:274.40Amlodipine Besylate
CAS:Amlodipine Besylate(Amlodipine benzenesulfonate) is a long-lasting calcium channel blocker.Formula:C26H31ClN2O8SPurity:96.67% - 99.92%Color and Shape:SolidMolecular weight:567.05(E/Z)-Sivopixant
CAS:(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.Formula:C25H22ClN5O5Purity:99.82%Color and Shape:SolidMolecular weight:507.93Ref: TM-T9653
1mg92.00€5mg200.00€1mL*10mM (DMSO)225.00€10mg299.00€25mg484.00€50mg658.00€100mg892.00€500mg1,773.00€Dofequidar fumarate
CAS:Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through theFormula:C34H35N3O7Purity:99.93%Color and Shape:SolidMolecular weight:597.66Ref: TM-T11071
1mg37.00€2mg52.00€5mg80.00€1mL*10mM (DMSO)90.00€10mg118.00€25mg233.00€50mg447.00€100mg650.00€500mg1,369.00€Dooku1
CAS:Dooku1, Yoda1 analog, blocks Piezo1 channels, halting Ca2+ entry. IC50: 1.3μM in HEK 293, 1.5μM in HUVEC, stops Yoda1's aortic relaxation.Formula:C13H9Cl2N3OSPurity:98.87% - 99.74%Color and Shape:SolidMolecular weight:326.2Ref: TM-T11076
1mg43.00€2mg56.00€1mL*10mM (DMSO)90.00€5mg93.00€10mg133.00€25mg259.00€50mg482.00€100mg695.00€Furosemide sodium
CAS:Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formula:C12H10ClN2NaO5SPurity:99.52% - >99.99%Color and Shape:SolidMolecular weight:352.73Otilonium bromide
CAS:Otilonium bromide (SP63) , an antimuscarinic, is utilized as a spasmolytic agent.Formula:C29H43BrN2O4Purity:99.78% - 99.88%Color and Shape:SolidMolecular weight:563.57Carboxyamidotriazole Orotate
CAS:Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signalingFormula:C22H16Cl3N7O6Purity:99.37%Color and Shape:SolidMolecular weight:580.76Ethaverine hydrochloride
CAS:Ethaverine hydrochloride is a homologue of papaverine and is used as a vasodilator and antispasmodic.Cost-effective and quality-assured.Formula:C24H30ClNO4Purity:99.66% - 99.73%Color and Shape:SolidMolecular weight:431.96NS13001
CAS:NS13001, an oral SK channel modulator, shows promise for SCA2 therapy; EC50: 1.8 µM (SK2), 0.14 µM (SK3).Formula:C17H16ClN7Purity:99.55%Color and Shape:White SolidMolecular weight:353.81Torsemide
CAS:Torsemide (AC-4464), a sulfonylurea loop diuretic, has a long action duration, high plasma protein binding, and a long half-life.Formula:C16H20N4O3SPurity:99.81%Color and Shape:SolidMolecular weight:348.42Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formula:C11H15NO5Purity:99.96%Color and Shape:White SolidMolecular weight:241.24ML418
CAS:ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.Formula:C19H24ClN3O3Purity:99.3%Color and Shape:SolidMolecular weight:377.87Ref: TM-T16110
1mg37.00€5mg79.00€1mL*10mM (DMSO)84.00€10mg111.00€25mg178.00€50mg288.00€100mg414.00€200mg583.00€γ-Aminobutyric acid
CAS:γ-Aminobutyric acid (4-Aminobutyric acid) is the most common inhibitory neurotransmitter in the central nervous system.Formula:C4H9NO2Purity:99.95%Color and Shape:White SolidMolecular weight:103.12Baclofen
CAS:Baclofen (Lioresal), a chlorophenyl-butanoic acid derivative, treats spasms from spinal cord injury and MS by mimicking GABA at GABA-B receptors.Formula:C10H12ClNO2Purity:98% - 99.94%Color and Shape:White SolidMolecular weight:213.66NBQX disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Formula:C12H6N4Na2O6SPurity:97.32% - 97.6%Color and Shape:Brown SolidMolecular weight:380.2415Prilocaine hydrochloride
CAS:Prilocaine HCl: local amino amide anesthetic, blocks voltage-gated sodium channels in neurons, inhibits Na+ permeability.Formula:C13H21ClN2OPurity:99.97%Color and Shape:SolidMolecular weight:256.77Suloctidil
CAS:Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders.Formula:C20H35NOSPurity:99.75% - >99.99%Color and Shape:White SolidMolecular weight:337.56VU6036720
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuitFormula:C20H22ClFN4O2SPurity:98.1%Color and Shape:SolidMolecular weight:436.93PSB-12062
CAS:PSB-12062 (N-(p-Methylphenylsulfonyl)phenoxazine) is a potent and selective antagonist of P2X4(IC50 of 1.38 μM for human P2X4).Formula:C19H15NO3SPurity:99.43% - 99.84%Color and Shape:SolidMolecular weight:337.39TRPV4 agonist-1 free base
CAS:TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).Formula:C25H22F2N4O2Purity:99.79%Color and Shape:SolidMolecular weight:448.46IA-Alkyne
CAS:IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Formula:C8H12INOPurity:99.76%Color and Shape:White SolidMolecular weight:265.09Ref: TM-T15543
1mg56.00€1mL*10mM (DMSO)114.00€5mg119.00€10mg177.00€25mg250.00€50mg313.00€100mg432.00€BMS-394136
CAS:BMS-394136 (BMS 394136) is a KV1.5 antagonist for the treatment of cardiovascular diseases such as arrhythmias and atrial fibrillation.Formula:C24H21Cl2FN4OPurity:98.59% - 99.95%Color and Shape:White SolidMolecular weight:471.35NS3623
CAS:NS3623 is an activator of human ether-a-go-go-related gene potassium channels.Formula:C15H10BrF3N6OPurity:97.06%Color and Shape:SolidMolecular weight:427.18ATP synthase inhibitor 1
CAS:ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex.Formula:C17H18ClN3O3S2Purity:99.83%Color and Shape:SolidMolecular weight:411.934-Aminopyridine
CAS:4-Aminopyridine (Dalfampridine) is a nonselective potassium (K+) channel blocker that binds to the cytoplasmic side of the cell membrane.Formula:C5H6N2Purity:91.61%Color and Shape:SolidMolecular weight:94.11JNJ-61432059
CAS:JNJ-61432059 is an oral active and selective negative modulator of TARP γ‑8 Selective AMPAR(pIC50: 9.7).Formula:C25H22FN5O2Purity:99.65%Color and Shape:SolidMolecular weight:443.47Ref: TM-T15623
1mg94.00€5mg222.00€1mL*10mM (DMSO)245.00€10mg318.00€25mg532.00€50mg708.00€100mg945.00€200mg1,279.00€
