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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8626 products of "Metabolism"

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  • PR280


    <p>PR280 is a potent inhibitor of dihydroceramide desaturase 1 (Des1) with an IC50 of 700 nM. It forms hydrogen bonds with amino acid residues of Des1, while its cyclopropenone group may coordinate with the iron center, stabilizing its binding at Des1's active site. This inhibits the ceramide biosynthesis pathway, preventing dihydroceramide (dhCer) from converting into ceramide. PR280 can be used in research related to sphingolipid metabolism disorders, including cancer and metabolic diseases.</p>
    Formula:C27H49NO4
    Molecular weight:451.36616
  • WWL123

    CAS:
    <p>WWL123 is a potent and selective ABHD6 inhibitor (IC50=430 nM).</p>
    Formula:C28H24N2O3
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:436.5
  • hCAIX/XII-IN-7


    <p>Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM for</p>
    Formula:C17H14N6O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:382.4
  • HIF-1α-IN-2 hydrochloride


    <p>HIF-1α-IN-2 hydrochloride is a potent HIF-1α inhibitor exhibiting anticancer activity, demonstrated by IC50 values of 28 nM in MDA-MB-231 cells and 15 nM in</p>
    Formula:C21H20ClN3OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:397.92
  • α-Glucosidase-IN-32


    <p>α-Glucosidase-IN-32 (compound f26) is a reversible, noncompetitive inhibitor of α-glucosidase that is orally active and exhibits an IC50 of 3.07 μM.</p>
    Formula:C32H22N4OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:510.61
  • HIF-1 α (556-574) (TFA)


    <p>HIF-1 alpha (556-574) TFA is a 19-residue fragment of hypoxia-inducible factor-1 (HIF-1), which serves as the master regulator of oxygen homeostasis [1].</p>
    Purity:98%
    Color and Shape:Odour Solid
  • Microginin 527

    CAS:
    <p>Microginin 527, a compound found in Microcystis, is an inhibitor of protein phosphatase, ACE, and leucine aminopeptidase.</p>
    Formula:C25H41N3O7S
    Color and Shape:Solid
    Molecular weight:527.67
  • (25R)-12α-Hydroxyspirost-4-en-3-one

    CAS:
    <p>'(25R)-12α-Hydroxyspirost-4-en-3-one is a minor metabolite resulting from Nocardia globerula's metabolization of Hecogenin [1].'</p>
    Formula:C27H40O4
    Color and Shape:Solid
    Molecular weight:428.6
  • Nampt degrader-2


    <p>Nampt degrader-2: a fluorescent PROTAC that degrades NAMPT at IC50 41.9 nM, reducing NAD+ and having anti-tumor effects.</p>
    Formula:C59H73N9O7S
    Color and Shape:Solid
    Molecular weight:1052.33
  • cis-5-Tetradecenoic acid

    CAS:
    <p>cis-5-Tetradecenoic acid, found in blood, helps study Long Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency.</p>
    Formula:C14H26O2
    Color and Shape:Solid
    Molecular weight:226.36
  • Acrihellin

    CAS:
    <p>Acrihellin is a cardioactive steroid, a cardiotonic drug.</p>
    Formula:C29H38O7
    Color and Shape:Solid
    Molecular weight:498.61
  • Aspergillomarasmine A

    CAS:
    <p>Aspergillomarasmine A is a polyamine acid naturally produced by the mold Aspergillus Versicolor.</p>
    Formula:C10H17N3O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:307.26
  • N-Trifluoroacetyladriamycin

    CAS:
    <p>N-Trifluoroacetyladriamycin, Valrubicin's metabolite, treats bladder cancer; it's an analog of doxorubicin, infused into the bladder.</p>
    Formula:C29H28F3NO12
    Color and Shape:Solid
    Molecular weight:639.533
  • PDK-IN-2


    <p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>
    Formula:C17H23AsCl2N2O2S2
    Color and Shape:Solid
    Molecular weight:497.33
  • A32390A

    CAS:
    <p>A32390A, an antibiotic inhibitor, shows antimicrobial activity against gram-positive bacteria and fungi.</p>
    Formula:C18H24N2O8
    Color and Shape:Solid
    Molecular weight:396.39
  • Rennin

    CAS:
    <p>Rennin or Chymosin, a stomach enzyme in some animals, curdles milk by cleaving K-casein; key in cheese making.</p>
    Color and Shape:Solid
  • α-1,3-N-Acetylgalactosaminyltransferase (Pm1138)

    CAS:
    <p>Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also known as the ABO system transferase, exhibits glycosyl transferase activity [1</p>
    Color and Shape:Solid
  • LYP-IN-3


    <p>LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway</p>
    Formula:C35H27NO6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:589.66
  • Nattokinase

    CAS:
    <p>Nattokinase is a serine protease derived from nattō, oral, fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.</p>
    Color and Shape:Solid
  • ω-Conotoxin CVIF


    <p>ω-Conotoxin CVIF is a selective inhibitor of Ca v 2.2 channels, demonstrating an IC50 value of 34.3 nM in isolated rat DRG neurons.</p>
    Formula:C101H170N40O33S6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2665.07