Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(138 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(66 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(4 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(8 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(134 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(84 products)
- ROR(47 products)
- Retinoid Receptor(26 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(45 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9245 products of "Metabolism"
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Monohydroxy Melphalan hydrochloride
CAS:Monohydroxy melphalan, a degradation product and DNA alkylating agent derived from melphalan, results from melphalan hydrolysis in aqueous solutions such as cell culture medium and human plasma. It enhances DNA adducts in ML-1 myeloblastic leukemia cells based on concentration and induces cytotoxicity with an IC50 value of 28.1 μg/ml.Formula:C13H19ClN2O3HClColor and Shape:SolidMolecular weight:359.68A 62198
CAS:A 62198 is a potent and selective renin inhibitor with potential as a hypotensive agent.Formula:C30H44N8O5Purity:98%Color and Shape:SolidMolecular weight:596.72C82
CAS:C82 acts as an inhibitor of Mycobacterium tuberculosis (Mtb) cyclic dinucleotide phosphodiesterase (CdnP), with an IC50 value of 17.5 µM. This particular enzyme is responsible for breaking down cyclic di-AMP (c-di-AMP) into adenosine 5'-monophosphate (AMP). Notably, C82 demonstrates selectivity for Mtb CdnP over other bacterial cyclic dinucleotide phosphodiesterases (CDN PDEs) such as Yybt, RocR, and Group B Streptococcus (GBS) CdnP, as well as the mammalian CDN PDE ENPP1, and the viral CDN PDE poxin, showing effectiveness at a concentration of 200 µM.Formula:C17H17N3O3SColor and Shape:SolidMolecular weight:343.4Tetramyristoylcardiolipin
CAS:Tetramyristoylcardiolipin (TMCL), an anionic lipid, plays a crucial role in studying cell membrane function and drug delivery mechanisms [1].Formula:C65H132N2O17P2Color and Shape:SolidMolecular weight:1275.69NTE-122
CAS:NTE-122 is a competitive Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor.Formula:C38H59ClN6O2Purity:98%Color and Shape:SolidMolecular weight:667.38CKD-519
CAS:CKD-519: A CETP inhibitor with an IC50 of 2.3 nM, blocking cholesteryl ester transfer in serum.Formula:C31H34F7NO3Color and Shape:SolidMolecular weight:601.6C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0)
CAS:C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is a lipid molecule that can be used in life science related research. The CAS number of C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is 34249-41-7.Formula:C36H71NO4Color and Shape:SolidMolecular weight:581.9671-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-PC
CAS:1-O-Hexadecyl-2-arachidonoyl-sn-glycero-3-PC undergoes acylation through the action of CoA-independent transacylase, transforming lyso-PAF C-16 into this compound. It serves as the predominant precursor in the biosynthesis of PAF C-16 via the remodeling pathway.Formula:C44H83NO7PColor and Shape:SolidMolecular weight:769.121Cintirorgon sodium
CAS:Cintirorgon (LYC-55716) is an oral RORgamma agonist with immunomodulatory and anticancer effects.Formula:C27H23F6NNaO6SPurity:98%Color and Shape:SolidMolecular weight:626.52NOX2-IN-1
CAS:NOX2-IN-1 (compound 10) serves as an inhibitor of the enzyme nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2).Formula:C22H22N4O3Color and Shape:SolidMolecular weight:390.44Sezolamide hydrochloride
CAS:Sezolamide hydrochloride is a potent topical carbonic anhydrase inhibitor.Formula:C11H19ClN2O4S3Color and Shape:SolidMolecular weight:374.93Eucalyptacid A
CAS:Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)Formula:C17H32O5Color and Shape:SolidMolecular weight:316.43TAS2R14 agonist-1
CAS:TAS2R14 agonist is a potent partial agonist of TAS2R14, displaying an EC50 value of 116.6 ± 23.6 nM [1].Formula:C15H9F6N5Color and Shape:SolidMolecular weight:373.2618-carboxy dinor Leukotriene B4
CAS:18-Carboxy dinor Leukotriene B4 (18-carboxy dinor LTB4) represents a β-oxidation metabolite of Leukotriene B4 (LTB4). Initially, LTB4 is metabolized in the liver to 20-carboxy LTB4, which subsequently undergoes β-oxidation to form 18-carboxy dinor LTB4.Formula:C18H26O6Color and Shape:SolidMolecular weight:338.4N-Stearoyl Taurine
CAS:N-Arachidonoyl dopamine (NADA) and N-Arachidonoyl serine (ARA-S), among various arachidonoyl amino acids, have been extracted from bovine brain, while a novel series of fatty acyl amides of taurine were unearthed in rat brain through mass spectral lipidomic analysis, indicating the discovery of a new class of compounds also located in the kidney. These compounds are known to activate members of the transient receptor potential (TRP) family of calcium channels. Notably, N-Stearoyl taurine emerges as a significant amino-acyl endocannabinoid identified in rat brain lipidomics profiling.Formula:C20H41NO4SColor and Shape:SolidMolecular weight:391.6113,14-dihydro-16,16-difluoro Prostaglandin E1
CAS:Prostaglandin E1 (PGE1), synthesized through cyclooxygenase-mediated metabolism of dihomo-γ-linolenic acid (DGLA), functions by inhibiting platelet aggregation (IC50= 40 nM) and enhancing vasodilation. Its analog, 13,14-dihydro-16,16-difluoro PGE1, and the metabolite, 13,14-dihydro PGE1, both retain similar anti-aggregatory properties to the original compound. The inclusion of two electron-withdrawing fluorine atoms in 13,14-dihydro-16,16-difluoro PGE1 is believed to increase molecular stability and potentially extend bioavailability by resisting hydrolytic degradation.Formula:C20H34F2O5Color and Shape:SolidMolecular weight:392.484Lp-PLA2-IN-2
CAS:Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.Formula:C19H23FN2O4SPurity:98%Color and Shape:SolidMolecular weight:394.46PDE1-IN-2
CAS:PDE1-IN-2 is an PDE1 inhibitor(PDE1C, PDE1B and PDE1A with IC50 values of 6, 140 and 164 nM, respectvely).Formula:C16H21BrN4O2Purity:98%Color and Shape:SolidMolecular weight:381.27(+)-Carbovir
CAS:(+)-Carbovir is a nucleoside analog with increased chemical stability and increased metabolic stability.Formula:C11H13N5O2Color and Shape:SolidMolecular weight:247.254-Hydroxyphenylglyoxylic Acid
CAS:4-Hydroxyphenylglyoxylic acid, an active metabolite of the prodrug oxfenicine, functions as an inhibitor of carnitine palmitoyltransferase 1 (CPT1).Formula:C8H6O4Color and Shape:SolidMolecular weight:166.13
