Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(138 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(85 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(134 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(169 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(86 products)
- ROR(47 products)
- Retinoid Receptor(22 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(45 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9185 products of "Metabolism"
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ATX inhibitor 21
CAS:ATX inhibitor 21 is a potent inhibitor of ATX (IC50: 3490 nM).Formula:C26H25F2N5O2SColor and Shape:SolidMolecular weight:509.572-Myristyldistearin
CAS:2-Myristyldistearin (SMS), a triacylglycerol comprising myristic acid and stearic acid [1], showcases its intricate structural composition.Formula:C53H102O6Color and Shape:SolidMolecular weight:835.37sEH/AChE-IN-4
CAS:sEH/AChE-IN-4-15 is a dual sEH and AChE inhibitor crossing the BBB, with IC50s: 3.1 nM (hsEH), 1660 nM (hAChE), 179 nM (hBChE), 14.5 nM (msEH), 102 nM (mAChE).Formula:C35H39ClF3N5O3Color and Shape:SolidMolecular weight:670.16Me-Indoxam
CAS:Me-Indoxam is an inhibitor of sPLA2. It has no effect on arachidonic acid release and platelet activating factor synthesis.Formula:C26H22N2O5Purity:98%Color and Shape:SolidMolecular weight:442.46CAY10502
CAS:CAY10502 inhibits cPLA2α (85 kDa), crucial in inflammation/arachidonic cascade, with 4.3 nM IC50, reducing arachidonic acid in human platelets.Formula:C30H37NO7Color and Shape:SolidMolecular weight:523.621a,1b-dihomo Prostaglandin F2α
CAS:1a,1b-Dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α), a hypothetical product of adrenic acid in the COX pathway, is predominantly synthesized in the renal medulla, reflecting the selective distribution of adrenic acid in this region.Formula:C22H38O5Color and Shape:SolidMolecular weight:382.5419-OxoODE
CAS:9-OxoODE, formed through the oxidation of the allylic hydroxyl group in both 9(S)-HODE and 9(R)-HODE, is present in rabbit reticulocyte plasma and mitochondrial membranes as both 9- and 13-oxoODEs, constituting approximately 2% of the total linoleate residues. The majority of these oxidized linoleate residues are esterified to membrane lipids.Formula:C18H30O3Color and Shape:SolidMolecular weight:294.4SHP2-IN-17
CAS:SHP2-IN-17 (compound 192) is a potent inhibitor of SHP2, exhibiting an IC50 of 2 nM and holds potential for use in glioblastoma research [1].Formula:C25H24Cl2N6Color and Shape:SolidMolecular weight:479.4Autotaxin-IN-4
CAS:Autotaxin-IN-4 is an Autotaxin inhibitor. It has the potential to treat idiopathic pulmonary fibrosis.Formula:C22H21N9O2Purity:98%Color and Shape:SolidMolecular weight:443.46II-B08
CAS:II-B08 is a cell-permeable SHP2 inhibitor (IC50 = 5.5 µM). II-B08 blocks growth factor stimulated ERK1/2 activation and hematopoietic progenitor proliferation.Formula:C33H27N5O4Color and Shape:SolidMolecular weight:557.6S-Benzylglutathione
CAS:S-Benzylglutathione acts as a competitive inhibitor of glutathionase and undergoes conversion by rat kidney microsomes into its cysteine derivatives.Formula:C17H23N3O6SColor and Shape:SolidMolecular weight:397.45ICMT-IN-21
CAS:ICMT-IN-21 (compound 6ag) is an ICMT inhibitor with an IC50 value of 8.8 µM, featuring sulfonamide-modified farnesyl cysteine (SMFC).Formula:C22H33NO4S3Color and Shape:SolidMolecular weight:471.7ICMT-IN-41
CAS:ICMT-IN-41 (compound 20) serves as a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.069 μM [1].Formula:C23H31NOColor and Shape:SolidMolecular weight:337.5Biliverdin
CAS:Biliverdin, produced through the oxidation of bilirubin, can also be synthesized through a non-protoporphyrin pathway in Corynebacterium glutamicum [1].Formula:C33H34N4O6Color and Shape:SolidMolecular weight:582.65Prostaglandin F2α-1-glyceryl ester
CAS:Prostaglandin F2α-1-glyceryl ester undergoes oxidation via 15-hydroxyprostaglandin dehydrogenase (15-HPGDH) [1].Formula:C23H40O7Color and Shape:SolidMolecular weight:428.5665-PAHSA
CAS:5-PAHSA, a FAHFA formed through the formal condensation of the carboxy group of palmitic acid with the hydroxy group of 5-hydroxystearic acid, serves as a human metabolite, possesses anti-inflammatory and hypoglycemic properties, and is categorized as a long-chain fatty acid. This compound, deriving from hexadecanoic acid and octadecanoic acid, is the conjugate acid of a 5-PAHSA(1-).Formula:C34H66O4Color and Shape:SolidMolecular weight:538.898BMS-186511
CAS:BMS-186511: An FT inhibitor targeting malignant cells in NF1, halting growth and spread without affecting related enzymes.Formula:C34H60N3O7PSColor and Shape:SolidMolecular weight:685.89cis-Clopidogrel-MP derivative
CAS:cis-Clopidogrel-MP derivative, also Clopidogrel-MP-AM, is a 3'-methoxyacetophenone Clopidogrel metabolite and oral P2Y12 receptor platelet inhibitor.Formula:C25H26ClNO6SColor and Shape:SolidMolecular weight:503.99FTI 276
CAS:FTI-276 is an inhibitor of protein farnesyltransferase (PFT) (IC50s: 0.9 and 0.5 nM for Plasmodium falciparum and human).Formula:C21H27N3O3S2Purity:98%Color and Shape:SolidMolecular weight:433.59BMS-654457
CAS:BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).Formula:C36H37N5O4Purity:98%Color and Shape:SolidMolecular weight:603.71
