Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(18 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9195 products of "Metabolism"
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Arachidonoyl-N-methyl amide
CAS:Anandamide (AEA), an endogenous cannabinoid, interacts with both central (CB1) and peripheral (CB2) cannabinoid receptors. Its effects are concluded through the cellular uptake and enzymatic breakdown of its amide bond by fatty acid amide hydrolase. Arachidonoyl-N-methyl amide, an analog of anandamide, specifically targets the human CB1 receptor, displaying a binding affinity with a Ki of 60 nM. It completely inhibits rat glial gap junction intercellular communication at a concentration of 50 µM.Formula:C21H35NOColor and Shape:SolidMolecular weight:317.57,7-Dimethyl-(5Z,8Z)-eicosadienoic acid
CAS:7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA, 5 μM) significantly impacts the response to βA(25-35) stimulation. It reduces the formation of ROS.Formula:C22H40O2Color and Shape:SolidMolecular weight:336.55Hypogeic acid
CAS:Hypogeic acid is isolable from cultures of autotrophic bacteria linked to sulfate accumulation in biofilters [1].Formula:C16H30O2Color and Shape:SolidMolecular weight:254.41ICMT-IN-27
CAS:ICMT-IN-27, also known as compound 64, is an inhibitor of the enzyme ICMT, demonstrating potent activity with an IC50 value of 0.1 µM [1].Formula:C22H28FNO2Color and Shape:SolidMolecular weight:357.46GNE-783
CAS:GNE-783 is a selective inhibitor of CHK1.Formula:C22H20N6Purity:98%Color and Shape:SolidMolecular weight:368.43Oxalomalic acid trisodium
CAS:Oxalomalic acid (Oxalomalate) trisodium, an inhibitor of aconitase and NADP-dependent isocitrate dehydrogenase, suppresses nitrite production and inducible nitric oxide synthase (iNOS) protein expression in lipopolysaccharide-activated J774 macrophages [1].Formula:C6H3Na3O8Color and Shape:SolidMolecular weight:272.05ICMT-IN-45
CAS:ICMT-IN-45 (compound 24) serves as an ICMT inhibitor, demonstrating an IC50 value of 0.132 μM [1].Formula:C24H33NOColor and Shape:SolidMolecular weight:351.521,2,3-Tritricosanoyl Glycerol
CAS:1,2,3-Tritricosanoyl glycerol, a triacylglycerol containing tricosanoic acid at the sn-1, sn-2, and sn-3 positions, serves as an internal standard for the quantification of fatty acids within the triglyceride component of human aortic endothelial cells (HAECs) cultured in media supplemented with stearic and/or oleic acid.Formula:C72H140O6Color and Shape:SolidMolecular weight:1101.88RXPA 380
CAS:RXPA 380: C-terminal ACE inhibitor, Ki=3nM; IC50=2.5nM for C-domain ACE mutants.Formula:C33H36N3O7PColor and Shape:SolidMolecular weight:617.63ICMT-IN-20
CAS:ICMT-IN-20 (compound 54) serves as an ICMT inhibitor with an IC50 value of 0.682 μM [1].Formula:C21H26N2O3Color and Shape:SolidMolecular weight:354.44GSK2973980A
CAS:GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).Formula:C25H19F5N4O4Purity:98%Color and Shape:SolidMolecular weight:534.43AA 863
CAS:AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.Formula:C21H26O5Purity:98%Color and Shape:SolidMolecular weight:358.43GGTI-2133
CAS:GGTI-2133: potent GGTase I inhibitor, IC50=38 nM; blocks inflammatory cell invasion in mice asthma.Formula:C27H28N4O3Purity:99.75%Color and Shape:SolidMolecular weight:456.54ERX-41
CAS:ERX-41 is an orally active, stereospecific small molecule that targets lysosomal acid lipase A (LIPA).Formula:C38H48N4O9Purity:98%Color and Shape:SolidMolecular weight:704.81SHP2-IN-17
CAS:SHP2-IN-17 (compound 192) is a potent inhibitor of SHP2, exhibiting an IC50 of 2 nM and holds potential for use in glioblastoma research [1].Formula:C25H24Cl2N6Color and Shape:SolidMolecular weight:479.4ICMT-IN-32
CAS:ICMT-IN-32 (compound 70) acts as an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.777 µM [1].Formula:C20H25NO2Color and Shape:SolidMolecular weight:311.42Lipid AX4
CAS:"Lipid AX4, characterized as an ionizable cationic lipid with a pKa of 6.89, facilitates the formation of lipid nanoparticles (LNPs) for in vivo mRNA delivery [1]."Formula:C83H155N3O16Color and Shape:SolidMolecular weight:1451.13hCAIX-IN-15
CAS:hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancerFormula:C18H14FN7O2SPurity:98%Color and Shape:SolidMolecular weight:411.41α-Glucosidase-IN-28
CAS:α-Glucosidase-IN-28 (Compound 18) is an α-glucosidase inhibitor with an IC50 of 0.62 μM and Ki value of 3.93 μM.Formula:C29H22Br2O7Purity:98%Color and Shape:SolidMolecular weight:642.29hCAIX/XII-IN-8
CAS:hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.Formula:C16H13Cl2N5O3SPurity:98%Color and Shape:SolidMolecular weight:426.28
