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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8597 products of "Metabolism"

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  • MAGL-IN-15
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    MAGL-IN-15

    CAS:
    <p>MAGL-IN-15 (Compound 6), a MAGL inhibitor, holds potential for research into diseases and disorders associated with the regulation of endocannabinoid system signaling activities [1].</p>
    Formula:C16H16F6N4O3
    Color and Shape:Solid
    Molecular weight:426.31

    Ref: TM-T86853

  • PF-07202954
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    PF-07202954

    CAS:
    <p>PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against</p>
    Formula:C22H23FN6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.45

    Ref: TM-T79764

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    HIF-1α-IN-5

    <p>HIF-1α-IN-5 is an inhibitor of HIF-1α with an IC 50 value of 24 nM in HEK293T cells that also inhibits the activity of MAO-A.</p>
    Formula:C16H15N3O2
    Color and Shape:Solid
    Molecular weight:281.31

    Ref: TM-T60532

  • Glucosylceramide synthase-IN-4
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    Glucosylceramide synthase-IN-4

    CAS:
    <p>Glucosylceramide Synthase-IN-4 (compound 12) serves as a potent inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 of 6.8 nM. It demonstrates superior pharmacokinetic properties and robust stability in human hepatocytes. Additionally, this compound is noted for its effective CNS penetration and acceptable PXR selectivity [1].</p>
    Formula:C22H18F5N3O3
    Color and Shape:Solid
    Molecular weight:467.39

    Ref: TM-T86511

  • ABHD antagonist 1
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    ABHD antagonist 1

    CAS:
    <p>ABHD antagonist 1 is an inhibitor of ABHD6 (α/β-Hydrolase domain containing 6), involved in modulating biochemical pathways affected by ABHD6, thereby influencing cell function and inflammatory responses. This compound is applicable for research in fields such as pain, neurological disorders, inflammatory diseases, autoimmune diseases, metabolic disorders, and cancer.</p>
    Formula:C19H20BrN3O3S
    Color and Shape:Solid
    Molecular weight:450.35

    Ref: TM-T88145

  • L-739750
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    L-739750

    CAS:
    <p>L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.</p>
    Formula:C23H39N3O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:517.7

    Ref: TM-T27773

  • DC371739
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    DC371739

    CAS:
    <p>DC371739 is an effective oral PCSK9 inhibitor that decreases both PCSK9 and ANGPTL3 mRNA expression. It also reduces PCSK9 protein expression while enhancing that of LDLR. Given its properties, DC371739 has potential applications in the study of hyperlipidemia.</p>
    Formula:C29H30N2O4
    Color and Shape:Solid
    Molecular weight:470.56

    Ref: TM-T88735

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    ALOX15-IN-1

    <p>ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.</p>
    Formula:C24H31N3O5S
    Color and Shape:Solid
    Molecular weight:473.59

    Ref: TM-T63075

  • Nampt activator-4
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    Nampt activator-4

    CAS:
    <p>Nampt activator-4, a positive allosteric modulator (N-PAM) of nicotinamide phosphoribosyltransferase (NAMPT), has an EC50 of 0.058 μM and can enhance nicotinamide adenine dinucleotide (NAD+) levels in cells [1].</p>
    Formula:C26H22F3N7OS
    Color and Shape:Solid
    Molecular weight:537.56

    Ref: TM-T86957

  • RORγt inhibitor 4
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    RORγt inhibitor 4

    CAS:
    <p>RORγt inhibitor 4 (Compound 9a) is an orally active RORγt inhibitor capable of penetrating the central nervous system. It has been shown to improve experimental autoimmune encephalomyelitis.</p>
    Formula:C22H16Cl2F3NO4S
    Color and Shape:Solid
    Molecular weight:518.333

    Ref: TM-T205045

  • P053
    Targetmol
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    P053

    CAS:
    <p>P053: potent, selective CerS1 inhibitor, IC50 = 0.5µM, curbs muscle fat oxidation, affects body fat.</p>
    Formula:C18H21Cl2NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.27

    Ref: TM-T12342

  • O-Desmethyl Brinzolamide hydrochloride
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    O-Desmethyl Brinzolamide hydrochloride

    CAS:
    <p>O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].</p>
    Formula:C11H20ClN3O5S3
    Color and Shape:Solid
    Molecular weight:405.94

    Ref: TM-T87055

  • CK1δ-IN-6
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    CK1δ-IN-6

    CAS:
    <p>CK1δ-IN-6 (Compound 303) is an inhibitor of Casein kinase 1δ, with potential applications in Alzheimer's disease research.</p>
    Formula:C23H17N3O4
    Color and Shape:Solid
    Molecular weight:399.399

    Ref: TM-T205075

  • SID 24785302
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    SID 24785302

    CAS:
    <p>SID 24785302 is an inhibitor of hexokinase, which can suppress glycolysis, regulate mitochondrial function, and ultimately inhibit the replication of mutant mitochondrial DNA.</p>
    Formula:C14H12N2O3S2
    Color and Shape:Solid
    Molecular weight:320.387

    Ref: TM-T205257

  • CymitQuimica logo
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    α-Glucosidase-IN-13

    <p>α-Glucosidase-IN-13 is an inhibitor of α-glucosidase (IC50: 5.69 μM).</p>
    Formula:C25H28N4O3S2
    Color and Shape:Solid
    Molecular weight:496.64

    Ref: TM-T63361

  • CymitQuimica logo
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    HIF-1α-IN-4

    <p>HIF-1α-IN-4 is an inhibitor of HIF-1α with IC50 of 24 nM in HEK293T cells which has potential antitumor effects.</p>
    Formula:C16H12N2O3
    Color and Shape:Solid
    Molecular weight:280.28

    Ref: TM-T60524

  • DX-9065A HCl hydrate
    Targetmol
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    DX-9065A HCl hydrate

    CAS:
    <p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>
    Formula:C26H39ClN4O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:571.06

    Ref: TM-T27224

  • APOL1-IN-3
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    APOL1-IN-3

    CAS:
    <p>APOL1-IN-3 is an APOL1 inhibitor used for kidney disease research.</p>
    Formula:C16H19F3N4O2S
    Color and Shape:Solid
    Molecular weight:388.41

    Ref: TM-T207131

  • Fmoc-NH-PEG6-alcohol
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    Fmoc-NH-PEG6-alcohol

    CAS:
    <p>Fmoc-NH-PEG6-alcohol, a cleavable ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs) [1].</p>
    Formula:C27H37NO8
    Color and Shape:Solid
    Molecular weight:503.58

    Ref: TM-T86468

  • PHD2-IN-4
    Targetmol
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    PHD2-IN-4

    CAS:
    <p>PHD2-IN-4 (compound 1) is an inhibitor of PHD2, with an IC50 of 4 nM. It is utilized in research related to chronic kidney disease.</p>
    Formula:C21H19N5O3
    Color and Shape:Solid
    Molecular weight:389.407

    Ref: TM-T205562