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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8597 products of "Metabolism"

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  • PDE4-IN-14

    CAS:
    <p>PDE4-IN-14 (Compound 1) serves as an inhibitor of phosphodiesterase 4 (PDE4), applicable in research concerning diseases associated with PDE4, including</p>
    Formula:C19H20F2N4O3S
    Color and Shape:Solid
    Molecular weight:422.45
  • Morocromen

    CAS:
    <p>Morocromen is a 2-benzamidobenzoic acid derivative characterized by its ability to enhance coronary activity.</p>
    Formula:C21H27N3O5
    Color and Shape:Solid
    Molecular weight:401.46
  • α-Amylase-IN-12

    CAS:
    <p>α-Amylase-IN-12 (Compound 5e) is an α-amylase inhibitor with an IC50 of 0.15 mM, functioning through a mixed inhibition mode. It exhibits an IC50 of 9.40 mM against α-glucosidase. This compound enhances glucose uptake in yeast cells and demonstrates significant anti-glycation activity at high concentrations. α-Amylase-IN-12 is applicable for diabetes research.</p>
    Formula:C16H11NO4
    Color and Shape:Solid
    Molecular weight:281.263
  • PDHK-IN-5


    <p>PDHK-IN-5, potent PDHK2 (0.006 μM IC50) &amp; PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.</p>
    Formula:C30H31N5O2
    Color and Shape:Solid
    Molecular weight:493.6
  • α-Glucosidase-IN-63

    CAS:
    <p>α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]</p>
    Formula:C16H12FN3O3S2
    Color and Shape:Solid
    Molecular weight:377.41
  • CYP121A1-IN-1


    <p>CYP121A1-IN-1: Strong inhibitor for CYP121A1, hinders Mycobacterium tuberculosis growth (MIC 90 ~6.25 μM), reduces mycocyclosin synthesis.</p>
    Formula:C22H20N4O
    Color and Shape:Solid
    Molecular weight:356.42
  • PTP1B-IN-21


    <p>PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.</p>
    Formula:C22H22O11
    Color and Shape:Solid
    Molecular weight:462.4
  • ABCB1-IN-4

    CAS:
    <p>ABCB1-IN-4 (Compound C6z) is an orally active inhibitor of α-amylase and α-glucosidase, with IC50 values of 1.63 μM and 0.14 μM, respectively. It holds potential for diabetes research.</p>
    Formula:C16H14N4S
    Color and Shape:Solid
    Molecular weight:294.374
  • Glucokinase activator 8

    CAS:
    <p>Glucokinase activator8 is an activator of glucose kinase (glucokinase).</p>
    Formula:C14H13N3O2S
    Color and Shape:Solid
    Molecular weight:287.337
  • E234G HYPE-IN-1

    CAS:
    <p>Compound I2.10 (E234G HYPE-IN-1) functions as an AMPylase inhibitor and exhibits low cytotoxicity toward human cell lines [1].</p>
    Formula:C14H9N5O2
    Color and Shape:Solid
    Molecular weight:279.25
  • VHR-IN-1

    CAS:
    <p>VHR-IN-1 (Compound SA1) is an effective and selective VHR phosphatase inhibitor with an IC50 of 18 nM. It hinders the proliferation of cervical cancer cells, demonstrating antitumor activity.</p>
    Formula:C28H22ClN3O5S3
    Color and Shape:Solid
    Molecular weight:612.139
  • ZSH-2208

    CAS:
    <p>ZSH-2208 is a retinoic acid A analogue that inhibits tumour cell proliferation and survival through RARγ-TNFAIP3 and retinoid receptors.</p>
    Formula:C20H18O3S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:338.42
  • PRL3-CNNM4 interaction-IN-1

    CAS:
    <p>PRL3-CNNM4 interaction-IN-1 (Compound C28d52) is an inhibitor of the PRL3-CNNM4 interaction that also suppresses CNNM inhibition mediated by PRL. This compound exhibits favorable pharmacokinetic and drug metabolism properties.</p>
    Formula:C8H8O2S
    Color and Shape:Solid
    Molecular weight:168.21
  • Sulclamide

    CAS:
    <p>Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].</p>
    Formula:C7H7ClN2O3S
    Color and Shape:Solid
    Molecular weight:234.66
  • Salacinol

    CAS:
    <p>Salacinol is a naturally occurring alpha-glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata.</p>
    Formula:C9H18O9S2
    Color and Shape:Solid
    Molecular weight:334.37
  • PPI-2458

    CAS:
    <p>PPI-2458, a fumagillin derivative, irreversibly blocks MetAP2, hindering abnormal cell growth and angiogenesis with improved toxicity.</p>
    Formula:C22H36N2O6
    Color and Shape:Solid
    Molecular weight:424.53
  • WAY-606344

    CAS:
    <p>WAY-606344 (Compound 97) is an inhibitor of Casein kinase 1δ and shows potential for Alzheimer's disease research.</p>
    Formula:C14H8ClN3O2
    Color and Shape:Solid
    Molecular weight:285.685
  • DDO-3055

    CAS:
    <p>DDO-3055 is an orally active PHD2 inhibitor utilized in studies related to anemia associated with chronic kidney disease.</p>
    Formula:C17H13ClN2O5
    Color and Shape:Solid
    Molecular weight:360.749
  • Carbonic anhydrase inhibitor 8


    <p>R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).</p>
    Formula:C20H25N3O4S
    Color and Shape:Solid
    Molecular weight:403.5
  • CK1δ-IN-7

    CAS:
    <p>CK1δ-IN-7 (Compound 488) is an inhibitor of casein kinase 1δ (CK1δ).</p>
    Formula:C23H23N5O
    Color and Shape:Solid
    Molecular weight:385.462