Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(139 products)
- DHFR(30 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(227 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(56 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(62 products)
- Lipoxygenase(133 products)
- MAO(85 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(170 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(85 products)
- ROR(47 products)
- Retinoid Receptor(18 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(30 products)
- Transporter(43 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9195 products of "Metabolism"
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RWJ-445167
CAS:RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Formula:C18H24N6O5SPurity:98%Color and Shape:SolidMolecular weight:436.49SHP2 IN-1
CAS:SHP2 IN-1 is an allergic SHP2 (PTPN11) inhibitor(IC50 : 3 nM).Formula:C18H22Cl2N6OSPurity:98%Color and Shape:SolidMolecular weight:441.38β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Formula:C31H23NO8Color and Shape:SolidMolecular weight:537.52CYP2C1/CYP2C19-IN-2
CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.Formula:C27H28N2O6SColor and Shape:SolidMolecular weight:508.59PKM2-IN-9
CAS:PKM2-IN-9 (compound C1) is a potent inhibitor of PKM2, demonstrating a 75% inhibition rate at 50 μM. It plays a significant role in cancer research.Formula:C24H22N4O2Color and Shape:SolidMolecular weight:398.4579(S)-HEPE
CAS:9(S)-HEPE is a monohydroxy fatty acid derived from EPA. The biological activity of 9(S)-HEPE has not been documented.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45HSD17B13-IN-17
CAS:HSD17B13-IN-17 (compound 9) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13). It demonstrates inhibitory efficacy with IC50 values of ＜0.1 μM for estradiol and ＜1 μM for Leukotriene B3 as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].Formula:C20H16ClFN2O3SColor and Shape:SolidMolecular weight:418.87L 668411
CAS:L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.Formula:C19H30O5Purity:98%Color and Shape:SolidMolecular weight:338.44PD-224378
CAS:PD-224378 is the lactam form of glycamine (β-isomer), produced through a Maillard reaction between pregabalin and lactose.Formula:C20H35NO11Color and Shape:SolidMolecular weight:465.492Mitapivat hydrochloride
CAS:Mitapivat (AG-348) hydrochloride is an orally active and selective allosteric activator of pyruvate kinase R (PK-R). It enhances the PK-R-catalyzed conversion of phosphoenolpyruvate to pyruvate, thereby promoting the glycolysis pathway, increasing ATP production in red blood cells, and decreasing 2,3-diphosphoglycerate (2,3-DPG) levels. Mitapivat hydrochloride is being investigated for potential use in the study of pyruvate kinase deficiency and other anemia-related disorders.Formula:C24H27ClN4O3SColor and Shape:SolidMolecular weight:487.014COTC
CAS:COTC is an anticancer bacterial metabolite; inhibits glyoxalase with GSH, halts HeLa cell growth, and fights tumor in Ehrlich murine model.Formula:C11H14O6Color and Shape:SolidMolecular weight:242.23hCA VB-IN-1
hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].Formula:C9H13N3O4SColor and Shape:SolidMolecular weight:259.28NADH-IN-2
CAS:NADH-IN-2 (compound 8) is a Type II NADH dehydrogenase inhibitor.Formula:C16H16N2Color and Shape:SolidMolecular weight:236.31Aripiprazole N,N-Dioxide
CAS:AripiprazoleN,N-Dioxide is a metabolite of the atypical antipsychotic drug aripiprazole, formed through its oxidation.Formula:C23H27Cl2N3O4Molecular weight:480.38Rostratin B
CAS:Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.Formula:C18H20N2O6S2Color and Shape:SolidMolecular weight:424.49Canosimibe
CAS:Canosimibe is a cholesterol absorption inhibitorFormula:C44H60FN3O10Color and Shape:SolidMolecular weight:809.96Mucidin
CAS:Mucidin is an antifungal antibiotic that inhibits electron transfer reactions within the mitochondrial respiratory chain's cytochrome bc1 complex.Formula:C16H18O3Molecular weight:258.31Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Color and Shape:SolidMolecular weight:454.56Anticancer agent 142
CAS:Compound 142 (also known as Compound 235) is a PTPN inhibitor with potential applications in cancer research [1].Formula:C13H14BrF2N2O7PS2Purity:98%Color and Shape:SolidMolecular weight:523.26PAT-347
CAS:PAT-347 is a potent inhibitor of Autotaxin, an enzyme linked to cell survival and diseases like cancer and fibrosis.Formula:C28H21ClF2N2O3SColor and Shape:SolidMolecular weight:538.99
