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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 9182 products of "Metabolism"

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  • HSD17B13-IN-17
    Targetmol
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    HSD17B13-IN-17

    CAS:
    HSD17B13-IN-17 (compound 9) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13). It demonstrates inhibitory efficacy with IC50 values of ＜0.1 μM for estradiol and ＜1 μM for Leukotriene B3 as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
    Formula:C20H16ClFN2O3S
    Color and Shape:Solid
    Molecular weight:418.87

    Ref: TM-T86607

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  • Dioctanoylphosphatidic acid sodium
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    Dioctanoylphosphatidic acid sodium

    CAS:
    Dioctanoylphosphatidic acid sodium serves as a modulator of phagocyte respiratory bursts, a precursor to diacylglycerol and lyso-phosphatidic acid, and influences the phosphorylation of the mammalian target of rapamycin (mTOR). Additionally, it enhances the viability of gallbladder cancer cells inhibited by histone deacetylase inhibitors (HDACI). This compound is derived from glycerophospholipids through the action of phospholipase D.
    Formula:C19H36NaO8P
    Color and Shape:Solid
    Molecular weight:446.45

    Ref: TM-T200919

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  • 7α,24(S)-Dihydroxycholesterol
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    7α,24(S)-Dihydroxycholesterol

    CAS:
    7α,24(S)-Dihydroxycholesterol ((3β,7α,24S)-Cholest-5-ene-3,7,24-triol) acts as a ligand for liver X receptors (LXR), specifically binding to the ligand-binding domains of LXRα and LXRβ. This compound is synthesized through the E-α,β-unsaturated ketone process, starting with arsindole and J-secondary-butyl dimethylsiloxy-bis-positive-5-cholestenal as the initial materials. It undergoes a series of transformations to produce 7α,24(S)-dihydroxycholesterol.
    Formula:C27H46O3
    Color and Shape:Solid
    Molecular weight:418.65

    Ref: TM-T200871

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  • DG013A
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    DG013A

    CAS:
    DG013A inhibits ERAP1 & ERAP2 (IC50: 33 nM & 11 nM) to research autoimmune diseases & cancer.
    Formula:C27H37N4O4P
    Color and Shape:Solid
    Molecular weight:512.58

    Ref: TM-T63546

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Propofol sulfate sodium
    Targetmol
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    Propofol sulfate sodium

    CAS:
    Propofolsulfate (sodium) is a metabolite of Propofol.
    Formula:C12H17NaO4S
    Color and Shape:Solid
    Molecular weight:280.316

    Ref: TM-TYD-02096

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  • BMS-185354
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    BMS-185354

    CAS:
    BMS-185354 is a selective RARγ activator with an EC50 value of 28 nM, offering potential for cancer research.
    Formula:C26H27NO3
    Color and Shape:Solid
    Molecular weight:401.497

    Ref: TM-T205728

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  • 3-Ferrocenylpropionic anhydride
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    3-Ferrocenylpropionic anhydride

    CAS:
    3-Ferrocenylpropionic anhydride is extensively used in compound synthesis, serving as an intermediary for producing various bioactive compounds. Additionally, by modulating specific enzyme activities, 3-Ferrocenylpropionic anhydride has demonstrated potential anti-tumor properties.
    Formula:C26H26Fe2O3
    Color and Shape:Solid
    Molecular weight:498.17

    Ref: TM-T201192

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  • 2,4-Dihydroxybutanoic acid
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    2,4-Dihydroxybutanoic acid

    CAS:
    2,4-Dihydroxybutanoic acid is typically not found in extracts of normal human urine and is present only in trace amounts in newborns, while cases of succinic semialdehyde dehydrogenase deficiency consistently exhibit elevated levels of this metabolite.
    Formula:C4H8O4
    Color and Shape:Solid
    Molecular weight:120.10

    Ref: TM-T201260

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  • RBM14C12
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    RBM14C12

    CAS:
    RBM14C12 is a compound known for its cell signaling activity. It plays a crucial role in researching lipid metabolism and cell membrane structure. Additionally, RBM14C12 can be utilized in the development of novel compounds aimed at modulating the biological mechanisms associated with lipid-related diseases.
    Formula:C26H39NO6
    Color and Shape:Solid
    Molecular weight:461.59

    Ref: TM-T201082

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • 4-Amino-3-hydroxyphenylalanine
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    4-Amino-3-hydroxyphenylalanine

    CAS:
    4-Amino-3-hydroxyphenylalanine (4-AHP) is a photodegradation product of eumelanin. It can be utilized in research focused on the formation of cutaneous melanoma and age-related macular degeneration.
    Formula:C9H12N2O3
    Color and Shape:Solid
    Molecular weight:196.203

    Ref: TM-TN10586

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  • Lipid 11
    Targetmol
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    Lipid 11

    CAS:
    Lipid 11 (Compound Lipid 1) is a cationic lipid designed for nucleic acid delivery. It forms lipid nanoparticles (LNPs) through electrostatic interactions with nucleic acids, such as ceDNA. By using its cationic amine groups, Lipid 11 complexes with negatively charged nucleic acids, enabling cellular uptake and release of the nucleic acid cargo. Lipid 11 shows potential for use in the development of gene therapy drug delivery systems.
    Formula:C43H85NO4
    Color and Shape:Solid
    Molecular weight:680.14

    Ref: TM-TCL-01218

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  • 9-cis-β-Carotene
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    9-cis-β-Carotene

    CAS:
    9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal.
    Formula:C40H56
    Purity:98%
    Color and Shape:Solid
    Molecular weight:536.87

    Ref: TM-T13524

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  • HSD17B13-IN-19
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    HSD17B13-IN-19

    CAS:
    HSD17B13-IN-19 (compound 16) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC50 values under 0.1 μM and under 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is crucial in the treatment of nonalcoholic fatty liver diseases (NAFLDs), such as nonalcoholic steatohepatitis (NASH) [1].
    Formula:C23H23FN2O4S
    Color and Shape:Solid
    Molecular weight:442.5

    Ref: TM-T86609

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  • DRX-065
    Targetmol
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    DRX-065

    CAS:
    DRX-065, a deuterated R-enantiomer of pioglitazone, treats NASH without PPARγ weight gain issues.
    Formula:C19H20N2O3S
    Color and Shape:Solid
    Molecular weight:357.45

    Ref: TM-T27210

    1mg
    628.00€
    5mg
    1,324.00€
    10mg
    1,791.00€
    25mg
    2,655.00€
    50mg
    3,582.00€
    100mg
    4,840.00€
  • ABT-046
    Targetmol
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    ABT-046

    CAS:
    ABT-046 is an orally active, selective, and highly efficient Diacylglycerol Acyltransferase 1 (DGAT-1) inhibitor that can be used in metabolic disease research.
    Formula:C20H22N4O2
    Purity:98.13%
    Color and Shape:Solid
    Molecular weight:350.41

    Ref: TM-T14085

    2mg
    139.00€
  • Nsp12-IN-2
    Targetmol
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    Nsp12-IN-2

    CAS:
    Nsp12-IN-2 (Compound 8), a triphosphate metabolite of 4'-thiouridine, functions as an inhibitor of SARS-CoV-2 Nsp12. It effectively suppresses the RNA-dependent RNA polymerase (RdRp) activity of the SARS-CoV-2 Nsp12-Nsp7-Nsp8 complex, halting RNA synthesis and blocking the RNA capping and NMP capping of Nsp9. Nsp12-IN-2 shows potential for research into infections caused by SARS-CoV-2, other coronaviruses, and additional RNA viruses.
    Formula:C9H12N2Na3O14P3S
    Color and Shape:Solid
    Molecular weight:566.15

    Ref: TM-T211588

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  • FXR agonist 12
    Targetmol
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    FXR agonist 12

    CAS:

    FXR agonist12 (Compound C7) is an orally active FXR agonist. It downregulates bile acid synthesis-related genes and upregulates bile acid transport-related genes in HepG2 cells. FXR agonist12 alleviates ANIT-induced cholestasis and reduces liver damage and fibrosis in a mouse model of NASH.

    Formula:C26H44O3
    Color and Shape:Solid
    Molecular weight:404.626

    Ref: TM-T205709

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  • MAFP
    Targetmol
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    MAFP

    CAS:
    MAFP (Methyl Arachidonyl Fluorophosphonate) is an effective irreversible inhibitor of anandamide amidase.
    Formula:C21H36FO2P
    Color and Shape:Solid
    Molecular weight:370.48

    Ref: TM-T15948

    1mg
    71.00€
    5mg
    216.00€
    10mg
    324.00€
    25mg
    535.00€
  • DLCI-1
    Targetmol
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    DLCI-1

    CAS:
    DLCI-1 is a potent and selective oral inhibitor of cytochrome P450 2A6 (CYP2A6), significantly reducing self-administered nicotine doses in both male and female mice.
    Formula:C12H14N2S
    Color and Shape:Solid
    Molecular weight:218.32

    Ref: TM-T201239

    25mg
    1,459.00€
    50mg
    1,963.00€
    100mg
    2,430.00€
  • (S)-CPP sodium
    Targetmol
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    (S)-CPP sodium

    CAS:
    (S)-CPP sodium serves as an inhibitor of the branched-chain α-keto acid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, (S)-CPP (IC50 of 6.3 μM) inhibits BDK, which activates the complex, leading to a significant reduction in the levels of leucine/isoleucine and valine in the plasma of wild-type mice.
    Formula:C9H8ClNaO2
    Color and Shape:Solid
    Molecular weight:206.60

    Ref: TM-T201099

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