Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(196 products)
- Casein Kinase(138 products)
- DHFR(32 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(64 products)
- FXR(62 products)
- Factor Xa(85 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(3 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(34 products)
- Hydroxylase(36 products)
- IDO(84 products)
- LDL(7 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(134 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(169 products)
- PED(1 products)
- PKM(17 products)
- PPAR(170 products)
- Phospholipase(86 products)
- ROR(47 products)
- Retinoid Receptor(22 products)
- SGK(10 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(45 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9185 products of "Metabolism"
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Complex III-IN-2
Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.Formula:C15H21ClN2O2SColor and Shape:SolidMolecular weight:328.86AZD 4407
CAS:AZD 4407 is a potent inhibitor of 5-lipoxygenase.Formula:C19H21NO3S2Purity:98%Color and Shape:SolidMolecular weight:375.5β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Formula:C31H23NO8Color and Shape:SolidMolecular weight:537.52Irafamdastat
CAS:Irafamdastat (BMS-986368) [Example 74] is an inhibitor of FAAH and MAGL, with IC50 values of ≤ 100 nM for human FAAH and 100 nM-1 μM for human MAGL. It exhibits anticonvulsant properties.Formula:C20H21F3N4O4Color and Shape:SolidMolecular weight:438.40SHP2-IN-43
CAS:SHP2-IN-43 (Compound 5) is an SHP2 inhibitor with an IC50 of 98.7 nM. It can be used as a PROTAC target protein ligand in the synthesis of SHP2-D26.Formula:C18H23ClN6OSColor and Shape:SolidMolecular weight:406.93D-2-Phosphoglyceric acid
CAS:D-2-Phosphoglyceric acid is a crucial metabolic intermediate known for its role in enhancing cellular energy metabolism and regulating biosynthesis. It plays a key role in both glycolysis and photosynthesis, which are essential for cellular energy supply. Additionally, D-2-Phosphoglyceric acid serves as a biomarker for monitoring metabolic states in various organisms.Formula:C3H7O7PColor and Shape:SolidMolecular weight:186.06Pyrocatechol sulfate
CAS:Pyrocatechol sulfate, a phenolic metabolite found in human plasma, is associated with the intake of specific foods such as berries and the state of the gut microbiome. It serves as a potential urinary biomarker for kidney function, dialysis clearance rates, whole grain consumption, and regular coffee intake. Additionally, in conjunction with other phenolic sulfates, pyrocatechol sulfate plays a role in regulating various biological functions, including those related to brain health and the rhythmic beating of cardiac cells.Formula:C6H6O5SColor and Shape:SolidMolecular weight:190.17HSD17B13-IN-30
CAS:HSD17B13-IN-30 (compound 64) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 value of less than 0.1 μM? with estradiol? as substrates. This compound is significantly implicated in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].Formula:C24H16Cl2F3N3O4Color and Shape:SolidMolecular weight:538.3EGFR/VEGFR2-IN-2
EGFR/VEGFR2-IN-2 (compound 4b) serves as a dual inhibitor of VEGFR-2 and EGFR.Formula:C24H15FO3Color and Shape:SolidMolecular weight:370.37CIT-ALD
CAS:CIT-ALD is an aldehyde intermediate formed during the metabolism of Citalopram. It has potential applications in the research of neurological disorders.Formula:C18H14FNO2Molecular weight:295.31Pefcalcitol
CAS:Pefcalcitol is a novel antipsoriatic prodrug candidate containing a 16-en-22-oxa-vitamin D3 structure.Formula:C26H34F5NO4Color and Shape:SolidMolecular weight:519.54Epoxykynin
CAS:Epoxykynin is a potent soluble epoxide hydrolase (sEH) inhibitor [1].Formula:C19H20BrF3N2O2Color and Shape:SolidMolecular weight:445.27TAK-915
CAS:TAK-915: potent, brain-ready PDE2A inhibitor, 0.61 nM IC50, 4100x selectivity over PDE1A.Formula:C19H18F4N4O5Purity:98%Color and Shape:SolidMolecular weight:458.36(+)-Potassium Ds-threo-isocitrate monobasic
CAS:(+)-Potassium Ds-threo-isocitrate monobasic is a bioactive compound known for its role in enhancing cellular metabolism and regulating energy production. This substance is also utilized in researching metabolic pathways and the regulation of enzyme activities. Widely applied in biochemical research, (+)-Potassium Ds-threo-isocitrate monobasic is studied for its potential functions in cellular processes and disease mechanisms.Formula:C6H7KO7Color and Shape:SolidMolecular weight:230.217(Z),11(Z)-Nonacosadiene
CAS:7(Z),11(Z)-Nonacosadiene, a female fly pheromone, spurs male courtship; it's a C29 diene made by a female-specific elongase.Formula:C29H56Color and Shape:SolidMolecular weight:404.757-hydroxychlorpromazine
CAS:7-Hydroxychlorpromazine, an active metabolite of Chlorpromazine, can reversibly counteract the suppression of regionally dense dopaminergic neurons induced by Amphetamine.Formula:C17H19ClN2OSColor and Shape:SolidMolecular weight:334.86Dopaminechrome
CAS:Dopaminechrome (DACHR) is an oxidation product of dopamine that promotes the generation of H2O2 at mitochondrial complex I in the brain in a concentration- and respiration-dependent manner. It possesses neurotoxic properties and can be utilized in Parkinson's disease research.
Formula:C8H7NO2Color and Shape:SolidMolecular weight:149.147L 731735
CAS:L 731735 is a farnesyltransferase inhibitor.Formula:C19H40N4O4SPurity:98%Color and Shape:SolidMolecular weight:420.61Vimirogant
CAS:Vimirogant is a RORγ inhibitor (Ki: <100 nM).Formula:C27H35F3N4O3SPurity:98%Color and Shape:SolidMolecular weight:552.65PHD2-IN-4
CAS:PHD2-IN-4 (compound 1) is an inhibitor of PHD2, with an IC50 of 4 nM. It is utilized in research related to chronic kidney disease.Formula:C21H19N5O3Color and Shape:SolidMolecular weight:389.407
