Metabolism
Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.
Subcategories of "Metabolism"
- AhR(42 products)
- Aminopeptidase(76 products)
- CETP(20 products)
- Carbonic Anhydrase(195 products)
- Casein Kinase(137 products)
- DHFR(34 products)
- Decarboxylase(4 products)
- Dehydrogenase(302 products)
- FAAH(66 products)
- FXR(62 products)
- Factor Xa(87 products)
- Fatty Acid Synthase(37 products)
- Ferroptosis(226 products)
- GR(3 products)
- GSNOR(4 products)
- Glucokinase(57 products)
- HIF/HIF Prolyl-Hydroxylase(146 products)
- HMG-CoA Reductase(33 products)
- Hydroxylase(35 products)
- IDO(84 products)
- LDL(8 products)
- Lipase(107 products)
- Lipid(61 products)
- Lipoxygenase(134 products)
- MAO(87 products)
- MPO(2 products)
- NAMPT(40 products)
- P450(6 products)
- PAI-1(26 products)
- PDE(167 products)
- PED(1 products)
- PKM(17 products)
- PPAR(169 products)
- Phospholipase(83 products)
- ROR(47 products)
- Retinoid Receptor(28 products)
- SGK(11 products)
- Thioredoxin(12 products)
- Transferase(29 products)
- Transporter(46 products)
- UGT(4 products)
- Xanthine Oxidase (XO) Inhibitors(9 products)
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Found 9275 products of "Metabolism"
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DSM705 hydrochloride
DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.Formula:C19H20ClF3N6OColor and Shape:SolidMolecular weight:440.85(3S,17S)-FD-895
CAS:(3S,17S)-FD-895 is an analogue of FD-895. It inhibits the growth of HCT116 cells and shows splicing-modulating activity. This compound can be utilized in cancer research.Formula:C31H50O9Color and Shape:SolidMolecular weight:566.723Casein kinase 1δ-IN-30
CAS:Casein kinase1δ-IN-30 (Compound 581) is an inhibitor of casein kinase 1δ (CK1δ). It can be utilized in research related to neurodegenerative diseases.Formula:C18H15BrN6O2SColor and Shape:SolidMolecular weight:459.32BT-114143
CAS:BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.Formula:C8H11N2O3PColor and Shape:SolidMolecular weight:214.158DPM-1003
CAS:DPM-1003 is an allosteric inhibitor of PTP1B, targeting the non-catalytic, disordered C-terminal segment of the PTP1B protein, and has shown beneficial effects in reducing pulmonary inflammation in mice.Formula:C35H57N3O3Color and Shape:SolidMolecular weight:567.845FXR agonist 12
CAS:<p>FXR agonist12 (Compound C7) is an orally active FXR agonist. It downregulates bile acid synthesis-related genes and upregulates bile acid transport-related genes in HepG2 cells. FXR agonist12 alleviates ANIT-induced cholestasis and reduces liver damage and fibrosis in a mouse model of NASH.</p>Formula:C26H44O3Color and Shape:SolidMolecular weight:404.626GK420
CAS:GK420 (AVX420) is a potent inhibitor of cytoplasmic phospholipase A2α (cPLA2α), with an XI(50) value of 0.0016. It effectively inhibits the release of arachidonic acid, with an EC50 of 0.09 μM. GK420 plays a significant role in cancer research.Formula:C20H25NO5SColor and Shape:SolidMolecular weight:391.481Enpp-1-IN-12
ENPP1-IN-12 is a potent, oral ENPP1 inhibitor with a Ki of 41 nM and anti-tumor properties.Formula:C17H19N5O3SColor and Shape:SolidMolecular weight:373.432R,4R-Sacubitril
CAS:2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.Formula:C24H29NO5Purity:98%Color and Shape:SolidMolecular weight:411.49HIF-2α-IN-7
CAS:HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor.Formula:C18H9F6NO2Color and Shape:SolidMolecular weight:385.26BAY 3389934
CAS:BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.Formula:C26H30ClN5O7S2Color and Shape:SolidMolecular weight:624.129AD015
CAS:AD015 is a dual inhibitor of angiotensin-converting enzyme (ACE) and neprilysin (NEP), effectively inhibiting NEP, nACE, and cACE with IC50 values of 0.009, 0.019, and 0.0008 μM, respectively.Formula:C23H26N2O4SColor and Shape:SolidMolecular weight:426.53IDO2-IN-1
CAS:IDO2-IN-1: potent oral IDO2 inhibitor, IC50 = 112 nM, for inflammatory autoimmunity research.Formula:C21H21BrN10O3Color and Shape:SolidMolecular weight:541.36Lipid 11
CAS:Lipid 11 (Compound Lipid 1) is a cationic lipid designed for nucleic acid delivery. It forms lipid nanoparticles (LNPs) through electrostatic interactions with nucleic acids, such as ceDNA. By using its cationic amine groups, Lipid 11 complexes with negatively charged nucleic acids, enabling cellular uptake and release of the nucleic acid cargo. Lipid 11 shows potential for use in the development of gene therapy drug delivery systems.Formula:C43H85NO4Color and Shape:SolidMolecular weight:680.14(rel)-Mirogabalin
CAS:(rel)-Mirogabalin ((rel)-DS5565) is an inhibitor of voltage-dependent calcium channels, specifically targeting the α2δ-1 subunit.Formula:C12H19NO2Color and Shape:SolidMolecular weight:209.28QGC583
CAS:QGC583 is an effective and selective AminopeptidaseA (APA) inhibitor, demonstrating an IC50 of 4 nM. It inhibits APA activity in the brain, kidneys, and heart of rats.Formula:C13H20NO5PColor and Shape:SolidMolecular weight:301.28Valerate sodium
CAS:<p>Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.</p>Formula:C5H9NaO2Purity:99.84%Color and Shape:SolidMolecular weight:124.11BI-4916
CAS:BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.Formula:C23H24Cl2N2O6SPurity:98.55%Color and Shape:SolidMolecular weight:527.42(R,R)-BMS-986397
CAS:(R,R)-BMS-986397 is a CK1α degrader with a DC50 ranging from 0.1 to 0.5 pM. This compound is applicable in leukemia research.Formula:C21H16ClF3N4O4Color and Shape:SolidMolecular weight:480.82Diacylglycerol acyltransferase inhibitor-2
CAS:Diacylglycerolacyltransferaseinhibitor-2 (Example 8) acts as an inhibitor for diacylglycerol acyltransferase 2 (DGAT2), exhibiting an IC50 value of 3.7 nM.Formula:C21H20FN5O4Color and Shape:SolidMolecular weight:425.41
