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Metabolism

Metabolism

Metabolism inhibitors are compounds that interfere with metabolic pathways, altering the production and utilization of energy within cells. These inhibitors are used to study the regulation of metabolism, the role of metabolic pathways in diseases like cancer and diabetes, and to develop new therapeutic strategies. Metabolism inhibitors can target various enzymes and processes involved in glycolysis, fatty acid oxidation, and other metabolic functions. At CymitQuimica, we offer a wide range of high-quality metabolism inhibitors to support your research in biochemistry, metabolic disorders, and drug development.

Subcategories of "Metabolism"

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Found 8595 products of "Metabolism"

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  • 9AzNue5Ac
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    9AzNue5Ac

    CAS:
    <p>9AzNue5Ac is a Neu5Ac analog that is metabolized in vivo in living cells and in mice.9AzNue5Ac binds to sialoglycans.</p>
    Formula:C11H18N4O8
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:334.28

    Ref: TM-T74989

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    PDE11A4-IN-1

    <p>PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2,</p>
    Color and Shape:Odour Solid

    Ref: TM-T81534

  • GS-704277
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    GS-704277

    CAS:
    <p>GS-704277, a Remdesivir metabolite, shows potent in vitro effects against COVID-19.</p>
    Formula:C15H19N6O8P
    Color and Shape:Solid
    Molecular weight:442.325

    Ref: TM-T37959

  • Acetoacetyl coenzyme A sodium
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    Acetoacetyl coenzyme A sodium

    CAS:
    <p>Acetoacetyl-CoA sodium is a key metabolite, with a Km of 1.10 mM at pH 7.5, used in PTB and PHB synthesis.</p>
    Formula:C25H37N7Na3O18P3S
    Color and Shape:Solid
    Molecular weight:917.55

    Ref: TM-T74172

  • TEI-9648
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    TEI-9648

    CAS:
    <p>TEI-9648: Potent, specific VDR antagonist, blocks 1α,25(OH)2D3 effects, may aid bone metabolism study.</p>
    Formula:C27H38O4
    Color and Shape:Solid
    Molecular weight:426.597

    Ref: TM-T36593

  • IGUANA-1 free base
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    IGUANA-1 free base

    CAS:
    <p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>
    Formula:C26H24ClN3O2
    Color and Shape:Solid
    Molecular weight:445.94

    Ref: TM-T72548

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    TDO-IN-2

    <p>TDO-IN-2 is an orally active TDO inhibitor with an IC50 of 1.25 μM. It exhibits antitumor activity in a Hepa1-6 liver cancer allograft mouse model. Additionally, TDO-IN-2 works synergistically with PD-1/PD-L1 inhibitor BMS-202, making it useful for studying tumor immune tolerance.</p>
    Formula:C20H15N3O3
    Color and Shape:Solid
    Molecular weight:345.11134

    Ref: TM-T207173

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    BDM_92499

    <p>BDM_92499 is a nanomolar, selective IRAP inhibitor with an IC50 of 3.4 nM. It also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively.</p>
    Color and Shape:Odour Solid

    Ref: TM-T206956

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    Antiproliferative agent-12

    <p>Antiproliferative agent-10, a ruthenium(II) complex, inhibits cancer by blocking mitochondrial calcium uptake.</p>
    Formula:C46H40Cl2N6P2Ru
    Color and Shape:Solid
    Molecular weight:910.79

    Ref: TM-T74921

  • Pi-Methylimidazoleacetic acid
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    Pi-Methylimidazoleacetic acid

    CAS:
    <p>Pi-Methylimidazoleacetic acid is a potential neurotoxin.</p>
    Formula:C6H8N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:140.14

    Ref: TM-T13820

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    DSPE-PEG1000-THRPPMWSPVWP

    <p>DSPE-PEG1000-THRPPMWSPVWP is a PEG compound composed of DSPE and the transferrin receptor (TfR) peptide. The THRPPMWSPVWP peptide binds to TfR and is subsequently internalized into cells expressing TfR.</p>
    Color and Shape:Odour Solid

    Ref: TM-TCL-01156

  • Angiotensinogen (1-14), human
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    Angiotensinogen (1-14), human

    CAS:
    <p>Angiotensinogen (1-14), human,Liver-synthesized globulin. Precursor to angiotensin I.</p>
    Formula:C83H122N24O19
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1760.01

    Ref: TM-TP1842

  • 10 FTHF disodium
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    10 FTHF disodium

    CAS:
    <p>10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate that is involved in the synthesis of purine compounds.</p>
    Formula:C20H21N7Na2O7
    Color and Shape:Solid
    Molecular weight:517.4

    Ref: TM-T73731

  • Penicitide A
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    Penicitide A

    CAS:
    <p>Penicitide A: marine metabolite, moderately cytotoxic to A. brassicae, HepG2 cells.</p>
    Formula:C18H34O4
    Color and Shape:Solid
    Molecular weight:314.46

    Ref: TM-T75454

  • Toddacoumalone
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    Toddacoumalone

    CAS:
    <p>Toddacoumalone, a natural PDE4 inhibitor, shows promise for inflammatory disease research.</p>
    Formula:C31H31NO6
    Color and Shape:Solid
    Molecular weight:513.58

    Ref: TM-T75486

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    PPARγ-IN-3

    <p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>
    Formula:C23H28FN7O3
    Color and Shape:Solid
    Molecular weight:469.51

    Ref: TM-T89904

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    Monoglyceride lipase

    CAS:
    <p>Monoglyceridelipase is a crucial enzyme involved in lipid metabolism, catalyzing the hydrolysis of monoglycerides (especially 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, this enzyme impacts neural signaling, pain perception, inflammatory responses, and metabolic processes.</p>
    Color and Shape:Solid

    Ref: TM-T200072

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    α-Glucosidase-IN-72

    <p>α-Glucosidase-IN-72 (compound 5i), a 2,4-dichloro-N-phenylacetamide derivative, functions as an α-glucosidase inhibitor with an inhibitory concentration (IC 50) of 6 μM. Notably, it does not adhere to Lipinski's "rule of five" and is not a cancer inducer.</p>
    Formula:C37H26Cl2N4O9
    Color and Shape:Solid
    Molecular weight:741.53

    Ref: TM-T200200

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    PP5-IN-2

    <p>PP5-IN-2, a selective and orally active inhibitor of protein phosphatase 5 (PP5), exhibits an IC 50 of 0.9 μM. This compound activates p53 and leads to the downregulation of cyclin D1 and MGMT, thereby inducing cell cycle arrest and reversing Temozolomide (TMZ) resistance in the U87 MG cell line. Additionally, PP5-IN-2 has demonstrated effective inhibition of tumor growth in the xenograft mouse model.</p>
    Formula:C16H15NO4
    Color and Shape:Solid
    Molecular weight:285.29

    Ref: TM-T89967

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    Penicillinase

    CAS:
    <p>Penicillinase is a β-lactamase and secretory enzyme capable of degrading and inactivating penicillin and similar compounds.</p>
    Color and Shape:Solid

    Ref: TM-T75391