Metabolism

<p>Cortisol sulfate sodium, a Cortisol metabolite, binds specifically to intracellular transcortin.</p>

<p>DSPE-PEG5000-EB1 is a PEGylated compound composed of DSPE and the pH-responsive transmembrane peptide (EB1). It is useful for drug delivery applications.</p>

<p>Tanshinone IIA anhydride: irreversible inhibitor for human CE1 (Ki=1.9 nM) and hiCE (Ki=1.4 nM).</p>

<p>1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting</p>

<p>Coproporphyrin I, an endogenous metabolite found in urine and blood, is utilized in researching liver disease and porphyria [1] [2] [3] [4].</p>

<p>(24S)-24,25-Dihydroxyvitamin D3 undergoes various levels of hydroxylation to form active vitamin D3 analogs.</p>

<p>CD13-IN-1 (Compound 5f) is a CD13 inhibitor with an IC50 value of 1.71 μM. It effectively suppresses the proliferation of various tumor cells, demonstrating antitumor activity.</p>

<p>Imidazole-d4 is an isotope-labeled variant of imidazole, which is a heterocyclic aromatic compound. Imidazole molecules serve as inhibitors for acetylcholinesterase (AChEI) and xanthine oxidase (XO) and have been utilized as corrosion inhibitors. They display a range of biological activities, including antifungal, antitubercular, anti-inflammatory, antioxidant, and analgesic properties. Imidazole inhibits platelet microsomes from converting endoperoxides (PGG2 and PGH2) into thromboxane A2. Additionally, imidazole derivatives show inhibitory effects on the SARS-CoV-2 3CLpro enzyme, offering potential for research in Alzheimer’s disease, gout, COVID-19, and thrombotic disorders.</p>

<p>DSPE-PEG2000-GRGDS is a PEG-based compound formed from DSPE and the anti-adhesion peptide (GRGDS). GRGDS serves to inhibit the binding and adhesion between the extracellular matrix and cell surface integrins. This compound is applicable in drug delivery.</p>

<p>Crelosidenib is a potent and selective mutant IDH inhibitor for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases.</p>

<p>Pi-Methylimidazoleacetic acid is a potential neurotoxin.</p>

<p>Penicillinase is a β-lactamase and secretory enzyme capable of degrading and inactivating penicillin and similar compounds.</p>

<p>N-Desalkyludenafil, a metabolite of Udenafil, functions as a PDE5 inhibitor and is utilized in the study of erectile dysfunction [1].</p>

<p>Diphlorethohydroxycarmalol is a useful organic compound for research related to life sciences and the catalog number is T125953.</p>

<p>Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

<p>N-Desethyl Sunitinib hydrochloride (SU-12662 hydrochloride) has potential anticancer activity and can be used to study cancer.</p>

<p>Porfimer sodium, a sodium salt with photodynamic properties, targets tumor cells and induces cytotoxicity with 630 nm laser activation.</p>

<p>α-Glucosidase-IN-50 (compound 8) acts as an inhibitor of α-Glucosidase.</p>

<p>DMPG sodium is a phospholipid analog commonly used in the preparation of artificial lipid bilayers to mimic the structure and function of biological membranes.</p>

<p>Corynecin IV is a metabolite similar to chloramphenicol, originally isolated from corynebacteria.</p>